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The map label for this gene is nahR [H]

Identifier: 66046144

GI number: 66046144

Start: 3496639

End: 3497553

Strand: Direct

Name: nahR [H]

Synonym: Psyr_2913

Alternate gene names: 66046144

Gene position: 3496639-3497553 (Clockwise)

Preceding gene: 66046138

Following gene: 66046147

Centisome position: 57.38

GC content: 63.93

Gene sequence:

>915_bases
ATGAATCGCAACGACCTGCGTCGCGTCGACCTCAATTTGCTCATCGTTTTCGAGACTCTGATGCATGAGCGCAGTGTCAC
GCGTGCGGCGGAAAAGCTGTTTCTCGGTCAGCCGGCAATCAGCGCTGCGCTGTCGCGGCTACGCGGCCTGTTCGATGATC
CACTGTTCGTGCGCACCGGGCGCAGCATGGAGCCCACCGCCCGAGCGACGGAAATCTTCGCCCTGCTCTCCCCCGCACTC
GACTCCATCTCGACAGCGGTCAGCCGCGCCTCGGAGTTCGACCCGGCGACCAGCACCTCGGTCTTCCGCATCGGCCTGTC
CGATGACGTCGAGTTCGCACTGTTGCCCACCCTGCTCAAGCGTCTGCGCTCCGAAGCGCCGGGCATTGTGCTGGTGGTCA
GACGGGTCAACTACATCCTCATGCCCCCCCTGCTCGCCTCCGGGGAGATATCGGTCGGCGTCAGCTACACACAAGACCTG
CCCGCCAACGCCAAGCGCAAGGTCCTGCGCAGGAGCAAGCCGCAATTGCTGCGCGCCGACTCGATACCCGGCCCGTTGAG
CCTCGACGACTTCTGCGCCCGCCCCCACGCACTGGTCTCCTTCGCCGGCGACCTGAGCGGGTTCATCGACGAACACCTGG
AAAAACTCGACCGCAAACGCCACGTCGTCCTCGCCGTGCCCCAGTTCAACGGCCTGGCCACACTACTCACCGGCACCGAC
ATCATCGCCACCGTGCCGGACTATGCGGCGCAGGTCCTGACTGCCGCGGGAGGCGTTCGCTCTGAAGACCTGCCGATTGA
AACCCGAACGTTCGAACTGCACATGGCCTGGCGCGGCGCGCAGGATAATGACCCCGGGGAGCGTTGGTTGAGGTCGCGGA
TTCAGATGTTTTTTGGGGATCCGGATAGTCTTTAG

Upstream 100 bases:

>100_bases
GTAACCCCCACAGTAATTTTCGCTGCGCCCGACCCGCATTTGCTCGTACTATCGCACCCTGCTCACGTCCTCAACCGACA
AATGGCCCGAGATATTCCGC

Downstream 100 bases:

>100_bases
GGGGCGTTGGGCAGGCTGTTTAGCTGGTTATTTCTGGCTTTTCATAGGTCATGGAGATGCAGTACTGCGCACGACAACTG
GTATCAAAAATACGACAGCT

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTGRSMEPTARATEIFALLSPAL
DSISTAVSRASEFDPATSTSVFRIGLSDDVEFALLPTLLKRLRSEAPGIVLVVRRVNYILMPPLLASGEISVGVSYTQDL
PANAKRKVLRRSKPQLLRADSIPGPLSLDDFCARPHALVSFAGDLSGFIDEHLEKLDRKRHVVLAVPQFNGLATLLTGTD
IIATVPDYAAQVLTAAGGVRSEDLPIETRTFELHMAWRGAQDNDPGERWLRSRIQMFFGDPDSL

Sequences:

>Translated_304_residues
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTGRSMEPTARATEIFALLSPAL
DSISTAVSRASEFDPATSTSVFRIGLSDDVEFALLPTLLKRLRSEAPGIVLVVRRVNYILMPPLLASGEISVGVSYTQDL
PANAKRKVLRRSKPQLLRADSIPGPLSLDDFCARPHALVSFAGDLSGFIDEHLEKLDRKRHVVLAVPQFNGLATLLTGTD
IIATVPDYAAQVLTAAGGVRSEDLPIETRTFELHMAWRGAQDNDPGERWLRSRIQMFFGDPDSL
>Mature_304_residues
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTGRSMEPTARATEIFALLSPAL
DSISTAVSRASEFDPATSTSVFRIGLSDDVEFALLPTLLKRLRSEAPGIVLVVRRVNYILMPPLLASGEISVGVSYTQDL
PANAKRKVLRRSKPQLLRADSIPGPLSLDDFCARPHALVSFAGDLSGFIDEHLEKLDRKRHVVLAVPQFNGLATLLTGTD
IIATVPDYAAQVLTAAGGVRSEDLPIETRTFELHMAWRGAQDNDPGERWLRSRIQMFFGDPDSL

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=27.2425249169435, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790147, Length=308, Percent_Identity=24.3506493506494, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081766, Length=126, Percent_Identity=32.5396825396825, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786820, Length=87, Percent_Identity=36.7816091954023, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33543; Mature: 33543

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECC
RSMEPTARATEIFALLSPALDSISTAVSRASEFDPATSTSVFRIGLSDDVEFALLPTLLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHH
RLRSEAPGIVLVVRRVNYILMPPLLASGEISVGVSYTQDLPANAKRKVLRRSKPQLLRAD
HHHHCCCCEEEEEECCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEECC
SIPGPLSLDDFCARPHALVSFAGDLSGFIDEHLEKLDRKRHVVLAVPQFNGLATLLTGTD
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCC
IIATVPDYAAQVLTAAGGVRSEDLPIETRTFELHMAWRGAQDNDPGERWLRSRIQMFFGD
CEEECHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
PDSL
CCCC
>Mature Secondary Structure
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECC
RSMEPTARATEIFALLSPALDSISTAVSRASEFDPATSTSVFRIGLSDDVEFALLPTLLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHH
RLRSEAPGIVLVVRRVNYILMPPLLASGEISVGVSYTQDLPANAKRKVLRRSKPQLLRAD
HHHHCCCCEEEEEECCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEECC
SIPGPLSLDDFCARPHALVSFAGDLSGFIDEHLEKLDRKRHVVLAVPQFNGLATLLTGTD
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCC
IIATVPDYAAQVLTAAGGVRSEDLPIETRTFELHMAWRGAQDNDPGERWLRSRIQMFFGD
CEEECHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
PDSL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]