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The map label for this gene is aroF [H]

Identifier: 66046131

GI number: 66046131

Start: 3478563

End: 3479645

Strand: Direct

Name: aroF [H]

Synonym: Psyr_2900

Alternate gene names: 66046131

Gene position: 3478563-3479645 (Clockwise)

Preceding gene: 66046130

Following gene: 66046132

Centisome position: 57.08

GC content: 63.16

Gene sequence:

>1083_bases
ATGAATTCGCCCGTTGCCGTAACCCCGTCCGACCTGTCCAGCCACGCCGTCAAGCTGGCAGACAACAGCCCCGTCTCGAA
ACGCCTGCCAGGTACTCTGGAATTGAAGATGCGTCTGCCCCTCGACGCAGCGCTCACCGAACAGGTTGCCAGCCATCGCC
GCGCCGTACGTGCCATCCTTGAAGGTCAGGACTCGCGACTGCTGGTCATCGTCGGCCCCTGCTCGATCCACGACCCTCGA
TCCGCCCTTGAATACGCTGAGCGACTGGCCGACCTTGCCGCGCAAGTCAGTGATCAGATGCTGCTGGTGATGCGCGCCTA
CGTCGAAAAACCGCGCACAACGGTGGGCTGGAAAGGTCTGGCTTACGATCCGCGCCTTGACGGCAGTGACGACATGGCCG
AGGGCCTGACGCTGTCGCGGCAATTGATGCTGGAGGTGCTGGGCCTGGGCCTGCCGATCGCCACCGAGATACTGCAACCG
ATGGCGGCCGGCTACTTCGACGACCTGCTCAGTTGGGTCGCGATTGGCGCTCGGACCACCGAATCGCAGATCCATCGGGA
AATGGCCAGCGGCCTGCCCATGGCCGTCGGTTTCAAGAACGGTACTGACGGCGGCGTGACGGTGGCCAGCGACGCGATGC
GCTCGGCTGCGCATCCGCATCGCCACTTTGGCATGGACGGTCATGGCCACCCGGCGATTATCGAGACGCAAGGCAATCCG
GATACGCACATCGTGCTACGCGGCGGCCACGGCGGGCCCAATTACGATCGCCAGAGTGTGGCCAAGGTGCAGGCGAGCCT
GAGCAAGAATAATGTCGCGTCGCGAATCATGGTCGATTGCAGCCACGCCAACAGTGGCAAGGACCCGCTGCGTCAGCCAG
GGGTGTTCGAGGACGTTCTGGAACAGCGCTTGTCAGGCAACACCTCGCTGATCGGCATGATGATCGAGAGCCACCTGTTC
GACGGCTGCCAGGCATTGGGCGGGACGCTGCAGTACGGCGTTTCGATCACCGACGGCTGCCTTGGCTGGGAAGGCACCGA
ACAACTGCTGCGTCGCGCGGTTGACCGTCTGCGTTACAGATAA

Upstream 100 bases:

>100_bases
TGCCAGGTGGCAAGCACATACCCCCGGTTCTAGAAGCCCTTTGTCGAACACCCCAGTAGGGTCTGCGCGGGAGCGTCCCG
CCAGCCCAGGAAGCCAGAAC

Downstream 100 bases:

>100_bases
ACAGAGCGACGGAACTTTGTCGGGAAATACCGCACTGAATCCGGTAGGCTGTTTCTTTTTTTTCACAGGAGATTATTCCC
CATGGCTAAAGCCACTGCCC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MNSPVAVTPSDLSSHAVKLADNSPVSKRLPGTLELKMRLPLDAALTEQVASHRRAVRAILEGQDSRLLVIVGPCSIHDPR
SALEYAERLADLAAQVSDQMLLVMRAYVEKPRTTVGWKGLAYDPRLDGSDDMAEGLTLSRQLMLEVLGLGLPIATEILQP
MAAGYFDDLLSWVAIGARTTESQIHREMASGLPMAVGFKNGTDGGVTVASDAMRSAAHPHRHFGMDGHGHPAIIETQGNP
DTHIVLRGGHGGPNYDRQSVAKVQASLSKNNVASRIMVDCSHANSGKDPLRQPGVFEDVLEQRLSGNTSLIGMMIESHLF
DGCQALGGTLQYGVSITDGCLGWEGTEQLLRRAVDRLRYR

Sequences:

>Translated_360_residues
MNSPVAVTPSDLSSHAVKLADNSPVSKRLPGTLELKMRLPLDAALTEQVASHRRAVRAILEGQDSRLLVIVGPCSIHDPR
SALEYAERLADLAAQVSDQMLLVMRAYVEKPRTTVGWKGLAYDPRLDGSDDMAEGLTLSRQLMLEVLGLGLPIATEILQP
MAAGYFDDLLSWVAIGARTTESQIHREMASGLPMAVGFKNGTDGGVTVASDAMRSAAHPHRHFGMDGHGHPAIIETQGNP
DTHIVLRGGHGGPNYDRQSVAKVQASLSKNNVASRIMVDCSHANSGKDPLRQPGVFEDVLEQRLSGNTSLIGMMIESHLF
DGCQALGGTLQYGVSITDGCLGWEGTEQLLRRAVDRLRYR
>Mature_360_residues
MNSPVAVTPSDLSSHAVKLADNSPVSKRLPGTLELKMRLPLDAALTEQVASHRRAVRAILEGQDSRLLVIVGPCSIHDPR
SALEYAERLADLAAQVSDQMLLVMRAYVEKPRTTVGWKGLAYDPRLDGSDDMAEGLTLSRQLMLEVLGLGLPIATEILQP
MAAGYFDDLLSWVAIGARTTESQIHREMASGLPMAVGFKNGTDGGVTVASDAMRSAAHPHRHFGMDGHGHPAIIETQGNP
DTHIVLRGGHGGPNYDRQSVAKVQASLSKNNVASRIMVDCSHANSGKDPLRQPGVFEDVLEQRLSGNTSLIGMMIESHLF
DGCQALGGTLQYGVSITDGCLGWEGTEQLLRRAVDRLRYR

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=321, Percent_Identity=53.8940809968847, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1786969, Length=336, Percent_Identity=48.8095238095238, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1787996, Length=327, Percent_Identity=48.6238532110092, Blast_Score=300, Evalue=9e-83,
Organism=Saccharomyces cerevisiae, GI6320240, Length=335, Percent_Identity=46.5671641791045, Blast_Score=317, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6319726, Length=330, Percent_Identity=46.969696969697, Blast_Score=304, Evalue=1e-83,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38841; Mature: 38841

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPVAVTPSDLSSHAVKLADNSPVSKRLPGTLELKMRLPLDAALTEQVASHRRAVRAIL
CCCCCCCCCCCCCHHEEEECCCCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
EGQDSRLLVIVGPCSIHDPRSALEYAERLADLAAQVSDQMLLVMRAYVEKPRTTVGWKGL
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AYDPRLDGSDDMAEGLTLSRQLMLEVLGLGLPIATEILQPMAAGYFDDLLSWVAIGARTT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ESQIHREMASGLPMAVGFKNGTDGGVTVASDAMRSAAHPHRHFGMDGHGHPAIIETQGNP
HHHHHHHHHCCCCEEEECCCCCCCCEEEHHHHHHHHCCCHHHCCCCCCCCCEEEEECCCC
DTHIVLRGGHGGPNYDRQSVAKVQASLSKNNVASRIMVDCSHANSGKDPLRQPGVFEDVL
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHH
EQRLSGNTSLIGMMIESHLFDGCQALGGTLQYGVSITDGCLGWEGTEQLLRRAVDRLRYR
HHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSPVAVTPSDLSSHAVKLADNSPVSKRLPGTLELKMRLPLDAALTEQVASHRRAVRAIL
CCCCCCCCCCCCCHHEEEECCCCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
EGQDSRLLVIVGPCSIHDPRSALEYAERLADLAAQVSDQMLLVMRAYVEKPRTTVGWKGL
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AYDPRLDGSDDMAEGLTLSRQLMLEVLGLGLPIATEILQPMAAGYFDDLLSWVAIGARTT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ESQIHREMASGLPMAVGFKNGTDGGVTVASDAMRSAAHPHRHFGMDGHGHPAIIETQGNP
HHHHHHHHHCCCCEEEECCCCCCCCEEEHHHHHHHHCCCHHHCCCCCCCCCEEEEECCCC
DTHIVLRGGHGGPNYDRQSVAKVQASLSKNNVASRIMVDCSHANSGKDPLRQPGVFEDVL
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHH
EQRLSGNTSLIGMMIESHLFDGCQALGGTLQYGVSITDGCLGWEGTEQLLRRAVDRLRYR
HHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]