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The map label for this gene is ppiC [H]

Identifier: 66046132

GI number: 66046132

Start: 3479727

End: 3480008

Strand: Direct

Name: ppiC [H]

Synonym: Psyr_2901

Alternate gene names: 66046132

Gene position: 3479727-3480008 (Clockwise)

Preceding gene: 66046131

Following gene: 66046133

Centisome position: 57.1

GC content: 56.03

Gene sequence:

>282_bases
ATGGCTAAAGCCACTGCCCGCCACATCCTTGTTTCGAGCGAAGAAAAATGCAACGAACTCAAGGCTCAGATCGAAGGCGG
CGCTGATTTCGCAGAAATCGCCAAGGCCAATTCCAGCTGCCCGTCGAGCCGTCAAGGCGGTGACCTGGGTTCGTTCGGTC
CAGGCCAGATGGTCAAGGAATTCGACACTGTCGTATTCAGCGCTCCGGTGAACACCGTTCAGGGTCCGGTAAAAACCCAA
TTCGGCTATCACCTGCTGGAAGTGACCAGCCGTCAGGACTGA

Upstream 100 bases:

>100_bases
CCGTCTGCGTTACAGATAAACAGAGCGACGGAACTTTGTCGGGAAATACCGCACTGAATCCGGTAGGCTGTTTCTTTTTT
TTCACAGGAGATTATTCCCC

Downstream 100 bases:

>100_bases
TCCTGCCGCGCCGGGTGCCAGACGGCTCATCTTCGGATGGGCCGTTTTTGTATGTGGTCGTTTTCAACAACACAGTGACC
CGGCATGCGCGCCGTGGCTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase C; Parvulin; Rotamase C [H]

Number of amino acids: Translated: 93; Mature: 92

Protein sequence:

>93_residues
MAKATARHILVSSEEKCNELKAQIEGGADFAEIAKANSSCPSSRQGGDLGSFGPGQMVKEFDTVVFSAPVNTVQGPVKTQ
FGYHLLEVTSRQD

Sequences:

>Translated_93_residues
MAKATARHILVSSEEKCNELKAQIEGGADFAEIAKANSSCPSSRQGGDLGSFGPGQMVKEFDTVVFSAPVNTVQGPVKTQ
FGYHLLEVTSRQD
>Mature_92_residues
AKATARHILVSSEEKCNELKAQIEGGADFAEIAKANSSCPSSRQGGDLGSFGPGQMVKEFDTVVFSAPVNTVQGPVKTQF
GYHLLEVTSRQD

Specific function: PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=92, Percent_Identity=55.4347826086957, Blast_Score=101, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21356303, Length=92, Percent_Identity=39.1304347826087, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 9902; Mature: 9771

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKATARHILVSSEEKCNELKAQIEGGADFAEIAKANSSCPSSRQGGDLGSFGPGQMVKE
CCCCCCHHEEECCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
FDTVVFSAPVNTVQGPVKTQFGYHLLEVTSRQD
HHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCCC
>Mature Secondary Structure 
AKATARHILVSSEEKCNELKAQIEGGADFAEIAKANSSCPSSRQGGDLGSFGPGQMVKE
CCCCCHHEEECCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
FDTVVFSAPVNTVQGPVKTQFGYHLLEVTSRQD
HHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]