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The map label for this gene is uvrC [H]

Identifier: 66046127

GI number: 66046127

Start: 3474485

End: 3476308

Strand: Reverse

Name: uvrC [H]

Synonym: Psyr_2896

Alternate gene names: 66046127

Gene position: 3476308-3474485 (Counterclockwise)

Preceding gene: 66046128

Following gene: 66046126

Centisome position: 57.05

GC content: 61.4

Gene sequence:

>1824_bases
ATGACCCAGACATTTGATCCAGGTGCATTTCTCGCGACCTGTAGCGGTCGCCCCGGCGTCTACCGTATGTTCGACGCCGA
AGCCACACTGCTTTACGTCGGCAAGGCCAAGAACCTCAAGAAGCGTCTTGCCAGCTACTTCCGCAAGACCGGACACGCGC
CCAAGACCGGAGCGCTGGTGTCGCGTATCGCCCAGATCGAAACCACCATCACGGGCAACGAAACCGAAGCGCTGTTGCTG
GAGCAGACCCTCATCAAGGAGTGGCGGCCCCCGTACAACATTCTCCTGCGTGACGATAAATCCTATCCCTATGTGTTTCT
GTCCGACAACGCCTTTCCGCGGCTGAGCATTCATCGTGGCACCAAGAAGGCCAAGGGTCGCTATTTCGGGCCTTACCCGA
GTGCGGGCGCGATTCGCGAGAGCCTCAGCCTGCTGCAGAAGACTTTCCAGGTACGGCAGTGCGAGGACAGCTACTTCAAG
AACCGCACCCGTCCTTGCCTGCAATATCAGATCAAACGCTGCAAAGGGCCGTGTGTCGGGCTGGTCGAGCCTGAGGTGTA
TGCCGAGGACGTACGTCACTCGGTAATGTTCCTCGAAGGGCGCAGCAATGCCTTGAGCGACGAGCTGAACGCGTCGATGG
AAAAAGCCGCGATGGCGCTCGATTTCGAACGCGCAGCCGAGTTGCGTGATCAGGTGGCCTTGTTGCGCCGCGTCCAGGAT
CAGCAAAGCATGGATGGCGGCACCGGCGATGTCGATGTGGTCGCCGCGTTCGTCAACCCTGGCGGTGCCTGCGTGCACTT
GATCAGCGTGCGGGGCGGGCGGGTGCTGGGCAGCAAGAACTTCTTCCCGCAGGTGGGCATAGAAGAGGAGGTCGGCGAAG
TGATGTCGGCATTCCTGGCTCAGTATTTCCTCGGCGGCATCGACCGTGAGCTGCCCGGCGAAGTCATCGTCAATGTCATC
AACGACGATTTCCCTGCGTTCGTCGACGCCGTCGAAGAGCTGCGCGGCGTCGAGATGGTCATCAGTCATCGCGTGCGCGG
CACTCGGGCGCGCTGGCAGCAAATGGCGGTCACCAATGCCGAGCAGGCGCTGACCGCGCGGCTGGCCAACCGTCAGCATG
TGGCGTCGCGGTTCGAAGCGCTGGCCAAGGTGCTGGGTCTCGAAGACCCGCCAATGCGCCTGGAATGCTACGACATCAGC
CACTCCAGCGGTGAGGCGACCGTAGCGTCGTGCGTGGTGTTCGGCCCCGAAGGCCCGATCAAGTCCGATTACCGGCGTTT
CAATATCGAAGGCGTGACGGCGGGCGACGACTACGCCGCCATGCACCAGGCGTTGACCCGACGTTACAGCCGCATCAAGG
CCGGGGAGGGCAAGTTGCCTGACGTGCTGCTGGTGGACGGCGGCAAGGGGCAGATGTCCATGGCGCGCGACGTGCTCAAT
GAATTACAGGTTCCTGAGCTCATCCTGCTCGGTGTTGCCAAGGGCACCACGCGCAAGGCCGGTTTCGAAACCCTGTACCT
GAACGACTCAGCACATGAATTCACGCTGCCCGGCGACTCTCCGGCCCTGCACCTTATCCAGCAGATTCGCGACGAAGCAC
ACCGTTTCGCAATCACCGGCCACCGTGCCCGTCGGGGCAAGACCCGGCGCACATCGACCCTTGAGGGCGTGGCGGGTGTC
GGGCCGACCCGGCGTCGAGACCTGCTCAAACATTTCGGCGGATTGCAGGAATTGTCCCGTGCCAGCATCGATGAAATAGC
AAAAGCACCCGGAATCAGCAAAAAGCTGGCAGAGTCGATTTATGCAAACCTGCACAGCGAGTAG

Upstream 100 bases:

>100_bases
CCTACCGATACCGTATCTTTGAAAAGCTCTCGATCAGCAGTGATGTTGAACTGGCTTTGCTCGCTGTACGTCACGGCATG
GTTGATGCCAGCGCCTGAAC

Downstream 100 bases:

>100_bases
AATGCTCGTTCACCTCGTAGCCAGTTGTGCCGATGAATATCCCTAATCTGATCACCGTACTACGCGTTTTACTGATTCCG
ATCTTCATTTTGTTGTTCTA

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MTQTFDPGAFLATCSGRPGVYRMFDAEATLLYVGKAKNLKKRLASYFRKTGHAPKTGALVSRIAQIETTITGNETEALLL
EQTLIKEWRPPYNILLRDDKSYPYVFLSDNAFPRLSIHRGTKKAKGRYFGPYPSAGAIRESLSLLQKTFQVRQCEDSYFK
NRTRPCLQYQIKRCKGPCVGLVEPEVYAEDVRHSVMFLEGRSNALSDELNASMEKAAMALDFERAAELRDQVALLRRVQD
QQSMDGGTGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVGEVMSAFLAQYFLGGIDRELPGEVIVNVI
NDDFPAFVDAVEELRGVEMVISHRVRGTRARWQQMAVTNAEQALTARLANRQHVASRFEALAKVLGLEDPPMRLECYDIS
HSSGEATVASCVVFGPEGPIKSDYRRFNIEGVTAGDDYAAMHQALTRRYSRIKAGEGKLPDVLLVDGGKGQMSMARDVLN
ELQVPELILLGVAKGTTRKAGFETLYLNDSAHEFTLPGDSPALHLIQQIRDEAHRFAITGHRARRGKTRRTSTLEGVAGV
GPTRRRDLLKHFGGLQELSRASIDEIAKAPGISKKLAESIYANLHSE

Sequences:

>Translated_607_residues
MTQTFDPGAFLATCSGRPGVYRMFDAEATLLYVGKAKNLKKRLASYFRKTGHAPKTGALVSRIAQIETTITGNETEALLL
EQTLIKEWRPPYNILLRDDKSYPYVFLSDNAFPRLSIHRGTKKAKGRYFGPYPSAGAIRESLSLLQKTFQVRQCEDSYFK
NRTRPCLQYQIKRCKGPCVGLVEPEVYAEDVRHSVMFLEGRSNALSDELNASMEKAAMALDFERAAELRDQVALLRRVQD
QQSMDGGTGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVGEVMSAFLAQYFLGGIDRELPGEVIVNVI
NDDFPAFVDAVEELRGVEMVISHRVRGTRARWQQMAVTNAEQALTARLANRQHVASRFEALAKVLGLEDPPMRLECYDIS
HSSGEATVASCVVFGPEGPIKSDYRRFNIEGVTAGDDYAAMHQALTRRYSRIKAGEGKLPDVLLVDGGKGQMSMARDVLN
ELQVPELILLGVAKGTTRKAGFETLYLNDSAHEFTLPGDSPALHLIQQIRDEAHRFAITGHRARRGKTRRTSTLEGVAGV
GPTRRRDLLKHFGGLQELSRASIDEIAKAPGISKKLAESIYANLHSE
>Mature_606_residues
TQTFDPGAFLATCSGRPGVYRMFDAEATLLYVGKAKNLKKRLASYFRKTGHAPKTGALVSRIAQIETTITGNETEALLLE
QTLIKEWRPPYNILLRDDKSYPYVFLSDNAFPRLSIHRGTKKAKGRYFGPYPSAGAIRESLSLLQKTFQVRQCEDSYFKN
RTRPCLQYQIKRCKGPCVGLVEPEVYAEDVRHSVMFLEGRSNALSDELNASMEKAAMALDFERAAELRDQVALLRRVQDQ
QSMDGGTGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVGEVMSAFLAQYFLGGIDRELPGEVIVNVIN
DDFPAFVDAVEELRGVEMVISHRVRGTRARWQQMAVTNAEQALTARLANRQHVASRFEALAKVLGLEDPPMRLECYDISH
SSGEATVASCVVFGPEGPIKSDYRRFNIEGVTAGDDYAAMHQALTRRYSRIKAGEGKLPDVLLVDGGKGQMSMARDVLNE
LQVPELILLGVAKGTTRKAGFETLYLNDSAHEFTLPGDSPALHLIQQIRDEAHRFAITGHRARRGKTRRTSTLEGVAGVG
PTRRRDLLKHFGGLQELSRASIDEIAKAPGISKKLAESIYANLHSE

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=51.8032786885246, Blast_Score=640, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 67093; Mature: 66962

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTFDPGAFLATCSGRPGVYRMFDAEATLLYVGKAKNLKKRLASYFRKTGHAPKTGALV
CCCCCCCCCEEEEECCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHH
SRIAQIETTITGNETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDNAFPRLSIHRG
HHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCCEEEEECC
TKKAKGRYFGPYPSAGAIRESLSLLQKTFQVRQCEDSYFKNRTRPCLQYQIKRCKGPCVG
CHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEE
LVEPEVYAEDVRHSVMFLEGRSNALSDELNASMEKAAMALDFERAAELRDQVALLRRVQD
CCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQSMDGGTGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVGEVMSAFLA
HHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHH
QYFLGGIDRELPGEVIVNVINDDFPAFVDAVEELRGVEMVISHRVRGTRARWQQMAVTNA
HHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCH
EQALTARLANRQHVASRFEALAKVLGLEDPPMRLECYDISHSSGEATVASCVVFGPEGPI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCC
KSDYRRFNIEGVTAGDDYAAMHQALTRRYSRIKAGEGKLPDVLLVDGGKGQMSMARDVLN
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHH
ELQVPELILLGVAKGTTRKAGFETLYLNDSAHEFTLPGDSPALHLIQQIRDEAHRFAITG
HCCCCCEEEEECCCCCCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHEEEEC
HRARRGKTRRTSTLEGVAGVGPTRRRDLLKHFGGLQELSRASIDEIAKAPGISKKLAESI
CHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHH
YANLHSE
HHHCCCC
>Mature Secondary Structure 
TQTFDPGAFLATCSGRPGVYRMFDAEATLLYVGKAKNLKKRLASYFRKTGHAPKTGALV
CCCCCCCCEEEEECCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHH
SRIAQIETTITGNETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDNAFPRLSIHRG
HHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCCEEEEECC
TKKAKGRYFGPYPSAGAIRESLSLLQKTFQVRQCEDSYFKNRTRPCLQYQIKRCKGPCVG
CHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEE
LVEPEVYAEDVRHSVMFLEGRSNALSDELNASMEKAAMALDFERAAELRDQVALLRRVQD
CCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQSMDGGTGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVGEVMSAFLA
HHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHH
QYFLGGIDRELPGEVIVNVINDDFPAFVDAVEELRGVEMVISHRVRGTRARWQQMAVTNA
HHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCH
EQALTARLANRQHVASRFEALAKVLGLEDPPMRLECYDISHSSGEATVASCVVFGPEGPI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCC
KSDYRRFNIEGVTAGDDYAAMHQALTRRYSRIKAGEGKLPDVLLVDGGKGQMSMARDVLN
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHH
ELQVPELILLGVAKGTTRKAGFETLYLNDSAHEFTLPGDSPALHLIQQIRDEAHRFAITG
HCCCCCEEEEECCCCCCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHEEEEC
HRARRGKTRRTSTLEGVAGVGPTRRRDLLKHFGGLQELSRASIDEIAKAPGISKKLAESI
CHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHH
YANLHSE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA