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The map label for this gene is dhaR [H]

Identifier: 66045990

GI number: 66045990

Start: 3342197

End: 3342856

Strand: Reverse

Name: dhaR [H]

Synonym: Psyr_2754

Alternate gene names: 66045990

Gene position: 3342856-3342197 (Counterclockwise)

Preceding gene: 66045997

Following gene: 66045989

Centisome position: 54.86

GC content: 61.06

Gene sequence:

>660_bases
ATGACTCAGCCAACCACCTCGCTACCCACTCCCTCACTCGCCAGGCCCCGGCGTCCCGGCCGGCCGCCAAAGGTTGATCG
CGATAATCTCGAGACCCGCGAGGCGCTGCTGCGCCGCGGTCTGGAAGTGCTCACCGAACAGAGTTTTTCGGCCACAGGGC
TTGATTACATCCTCAAGGAAGTCGGCATTCCCAAAGGGTCGTTCTATCACTACTTCCCCAGCAAGGAAGCCTTTGGCCGG
GCGGTGCTGGATGAGTACGCGCGCTATTTTGCGCAGCGGCTGGACCGCTGGCTGCTGGATGAAGCGCTTTCGCCACTGGA
GCGACTGGTCGGCTTTGTGCAGAGCGCCAAGGGCGGTATGGCGCGACACGACTATCGACGCGGTTGCATGGTCGGCAATC
TGGGCCAGGAAATCAGTCTGTTACCGGACGGATTTCGCGAGGCACTGGAACAGACGCTGCTGGACTGGCAGTCGAAACTG
GCGGGTTGTCTGAGGGCTGCGCAATCAATGGGCGAGTTGGCTGCAGACGCTGATTGCGATGAGCTGGCCGCGTTTTTCTG
GATCGGCTGGGAGGGCGCAGTGCTGCGTGCCCGGCTGGTTAAAAGCGCTACACCATTGAACACGTTCATTGCCGGCTACC
TTCGCGGTTTGCCGCAATGA

Upstream 100 bases:

>100_bases
GAGCGCGCGAATGGCGGGAATGGCAAACGCCACGTCGAGCGTCGACAAGCCGGCAGGGCCACTCGGTTGACATAAAAAAC
GATCGGTCTACTATTCGGGT

Downstream 100 bases:

>100_bases
TTTCTCTTCAGAACTATTTAAAGACGATCAGTCTAAATTGGAGGCGCATATGTTCAAGGGCATCTTGATCGACAAGGATG
AGGCGGGCTACCACGTCAAT

Product: regulatory protein, TetR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTQPTTSLPTPSLARPRRPGRPPKVDRDNLETREALLRRGLEVLTEQSFSATGLDYILKEVGIPKGSFYHYFPSKEAFGR
AVLDEYARYFAQRLDRWLLDEALSPLERLVGFVQSAKGGMARHDYRRGCMVGNLGQEISLLPDGFREALEQTLLDWQSKL
AGCLRAAQSMGELAADADCDELAAFFWIGWEGAVLRARLVKSATPLNTFIAGYLRGLPQ

Sequences:

>Translated_219_residues
MTQPTTSLPTPSLARPRRPGRPPKVDRDNLETREALLRRGLEVLTEQSFSATGLDYILKEVGIPKGSFYHYFPSKEAFGR
AVLDEYARYFAQRLDRWLLDEALSPLERLVGFVQSAKGGMARHDYRRGCMVGNLGQEISLLPDGFREALEQTLLDWQSKL
AGCLRAAQSMGELAADADCDELAAFFWIGWEGAVLRARLVKSATPLNTFIAGYLRGLPQ
>Mature_218_residues
TQPTTSLPTPSLARPRRPGRPPKVDRDNLETREALLRRGLEVLTEQSFSATGLDYILKEVGIPKGSFYHYFPSKEAFGRA
VLDEYARYFAQRLDRWLLDEALSPLERLVGFVQSAKGGMARHDYRRGCMVGNLGQEISLLPDGFREALEQTLLDWQSKLA
GCLRAAQSMGELAADADCDELAAFFWIGWEGAVLRARLVKSATPLNTFIAGYLRGLPQ

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=181, Percent_Identity=30.3867403314917, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24479; Mature: 24348

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPTTSLPTPSLARPRRPGRPPKVDRDNLETREALLRRGLEVLTEQSFSATGLDYILKE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VGIPKGSFYHYFPSKEAFGRAVLDEYARYFAQRLDRWLLDEALSPLERLVGFVQSAKGGM
HCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ARHDYRRGCMVGNLGQEISLLPDGFREALEQTLLDWQSKLAGCLRAAQSMGELAADADCD
HHHHHHCCCHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELAAFFWIGWEGAVLRARLVKSATPLNTFIAGYLRGLPQ
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQPTTSLPTPSLARPRRPGRPPKVDRDNLETREALLRRGLEVLTEQSFSATGLDYILKE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VGIPKGSFYHYFPSKEAFGRAVLDEYARYFAQRLDRWLLDEALSPLERLVGFVQSAKGGM
HCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ARHDYRRGCMVGNLGQEISLLPDGFREALEQTLLDWQSKLAGCLRAAQSMGELAADADCD
HHHHHHCCCHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELAAFFWIGWEGAVLRARLVKSATPLNTFIAGYLRGLPQ
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]