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The map label for this gene is yybE [H]

Identifier: 66045959

GI number: 66045959

Start: 3305185

End: 3306102

Strand: Direct

Name: yybE [H]

Synonym: Psyr_2723

Alternate gene names: 66045959

Gene position: 3305185-3306102 (Clockwise)

Preceding gene: 66045955

Following gene: 66045965

Centisome position: 54.24

GC content: 60.89

Gene sequence:

>918_bases
ATGTCCCTGACCCTGCGCCAGGTCCGTTATTTCGTGGCAACTGCCGAGATCGGGCAGATCTCGCAGGCCGCCATTCACCT
GAACATCTCCCAGTCGGCGGTCACCACGGCGATCAAGGAACTGGAGGGTATGCTCGGCACCCTGCTGTTTCAACGCTCGG
CGCAAGGCATGAGCCTGACTGAAGCAGGCCGTCATTTTCTCAACAGGGCTTACGTCATTCTGCGCAGCGTCGATGATGCG
CTGAACAGTCCGCTGCCCGATATCCGTGCCAGCGGCGTATTGCGCCTGGCCGCCAGCTACACGGTCATCGGCTACTTTCT
GCCGCATCATTTGCAGCGCCTGGAACACTGGCACCCGGACGTGGCCATCGAAGTGCATGAGCAGGAACGACACGCCATCG
AACAAGGCCTGCTGCAAGGTCGCTTCGACATGGCGGTGGTGCTGACAGCAAACATCACTCACCCGGATATTATCTCGGAA
ACGTTGTTCAACTCCGAGCGCCGCCTATGGCTGTCCAGCCATCACCCACTGTGCCAACGCGCTTCTGTCAGCCTCGCCGA
TGTCGCGCAGGAGCCCTATATCCTGTTGACCGTCGACGAAGCCGAACAAAGCGCCATGCGCTATTGGGAGCTGGCCGAAC
AGCAGCCCAACGTCAGAATCCGCACCAGCTCGGTGGAAGCCGTGCGCAGCATGGTCGCCAACGGCAGCGGCGTGGCAATC
CTTTCCGATCTGGTGCATCGCCCCTGGTCGCTGGAAGGCAAGCGTATCGAAACGATCACCGTCACCGACACGGTAACGCC
CATGAGCGTCGGCCTGGCCTGGCACCGCGAACGAGAACTGAGCCCGGCGATGCAGGCATTCCGCAACTATTTCCACGATG
CATTTCTGGCCCCGCAGCAACTGTCGGCACGGCGTTGA

Upstream 100 bases:

>100_bases
CGTTAAATTCAGTCGCACCCCTTGGGTAGATCTATTAACAGATACGCTATCTTCTGAAAAACAGATACCCCGCCCAGTGG
AACGTCTGTCTGGAGTGCTT

Downstream 100 bases:

>100_bases
ACCCGCGACACGCTATTGCGGATGGCGTGCCGGTGGCCGAGTGACCTGGCTGTATGGCTTTGATTTCGAGATCAAGGTCA
TCGCCAGGTTGCCGGAAGCC

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSLTLRQVRYFVATAEIGQISQAAIHLNISQSAVTTAIKELEGMLGTLLFQRSAQGMSLTEAGRHFLNRAYVILRSVDDA
LNSPLPDIRASGVLRLAASYTVIGYFLPHHLQRLEHWHPDVAIEVHEQERHAIEQGLLQGRFDMAVVLTANITHPDIISE
TLFNSERRLWLSSHHPLCQRASVSLADVAQEPYILLTVDEAEQSAMRYWELAEQQPNVRIRTSSVEAVRSMVANGSGVAI
LSDLVHRPWSLEGKRIETITVTDTVTPMSVGLAWHRERELSPAMQAFRNYFHDAFLAPQQLSARR

Sequences:

>Translated_305_residues
MSLTLRQVRYFVATAEIGQISQAAIHLNISQSAVTTAIKELEGMLGTLLFQRSAQGMSLTEAGRHFLNRAYVILRSVDDA
LNSPLPDIRASGVLRLAASYTVIGYFLPHHLQRLEHWHPDVAIEVHEQERHAIEQGLLQGRFDMAVVLTANITHPDIISE
TLFNSERRLWLSSHHPLCQRASVSLADVAQEPYILLTVDEAEQSAMRYWELAEQQPNVRIRTSSVEAVRSMVANGSGVAI
LSDLVHRPWSLEGKRIETITVTDTVTPMSVGLAWHRERELSPAMQAFRNYFHDAFLAPQQLSARR
>Mature_304_residues
SLTLRQVRYFVATAEIGQISQAAIHLNISQSAVTTAIKELEGMLGTLLFQRSAQGMSLTEAGRHFLNRAYVILRSVDDAL
NSPLPDIRASGVLRLAASYTVIGYFLPHHLQRLEHWHPDVAIEVHEQERHAIEQGLLQGRFDMAVVLTANITHPDIISET
LFNSERRLWLSSHHPLCQRASVSLADVAQEPYILLTVDEAEQSAMRYWELAEQQPNVRIRTSSVEAVRSMVANGSGVAIL
SDLVHRPWSLEGKRIETITVTDTVTPMSVGLAWHRERELSPAMQAFRNYFHDAFLAPQQLSARR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=300, Percent_Identity=27.6666666666667, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=28.4172661870504, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI157672245, Length=231, Percent_Identity=29.4372294372294, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787879, Length=310, Percent_Identity=28.7096774193548, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI145693105, Length=299, Percent_Identity=26.7558528428094, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786401, Length=302, Percent_Identity=25.1655629139073, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787530, Length=254, Percent_Identity=23.6220472440945, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081904, Length=200, Percent_Identity=30, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=23.5690235690236, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082132, Length=310, Percent_Identity=22.258064516129, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788748, Length=310, Percent_Identity=26.1290322580645, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790208, Length=298, Percent_Identity=25.503355704698, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=266, Percent_Identity=25.9398496240602, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=30.2013422818792, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789204, Length=300, Percent_Identity=25.3333333333333, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=272, Percent_Identity=25, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1788626, Length=274, Percent_Identity=25.9124087591241, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34289; Mature: 34157

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTLRQVRYFVATAEIGQISQAAIHLNISQSAVTTAIKELEGMLGTLLFQRSAQGMSLT
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EAGRHFLNRAYVILRSVDDALNSPLPDIRASGVLRLAASYTVIGYFLPHHLQRLEHWHPD
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VAIEVHEQERHAIEQGLLQGRFDMAVVLTANITHPDIISETLFNSERRLWLSSHHPLCQR
EEEEECHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEECCCCCHHHH
ASVSLADVAQEPYILLTVDEAEQSAMRYWELAEQQPNVRIRTSSVEAVRSMVANGSGVAI
HCCCHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCHHH
LSDLVHRPWSLEGKRIETITVTDTVTPMSVGLAWHRERELSPAMQAFRNYFHDAFLAPQQ
HHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHH
LSARR
HCCCC
>Mature Secondary Structure 
SLTLRQVRYFVATAEIGQISQAAIHLNISQSAVTTAIKELEGMLGTLLFQRSAQGMSLT
CCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EAGRHFLNRAYVILRSVDDALNSPLPDIRASGVLRLAASYTVIGYFLPHHLQRLEHWHPD
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VAIEVHEQERHAIEQGLLQGRFDMAVVLTANITHPDIISETLFNSERRLWLSSHHPLCQR
EEEEECHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEECCCCCHHHH
ASVSLADVAQEPYILLTVDEAEQSAMRYWELAEQQPNVRIRTSSVEAVRSMVANGSGVAI
HCCCHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCHHH
LSDLVHRPWSLEGKRIETITVTDTVTPMSVGLAWHRERELSPAMQAFRNYFHDAFLAPQQ
HHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHH
LSARR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]