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The map label for this gene is cbrB [H]

Identifier: 66045827

GI number: 66045827

Start: 3037694

End: 3038683

Strand: Direct

Name: cbrB [H]

Synonym: Psyr_2591

Alternate gene names: 66045827

Gene position: 3037694-3038683 (Clockwise)

Preceding gene: 66045826

Following gene: 66045828

Centisome position: 49.85

GC content: 64.34

Gene sequence:

>990_bases
ATGACGGCTGCGGCAAAACTGGGCCTGGGGCTGTTGATACTGGTAGCGTGCATGGGATTGAGTCTGGCCACTGGGGCCAC
CTGGATATCGCCCGCTGACATCGTGCGGAGTGTCTGGCAGCCGGATGCGCTGAGCGCTATCGAGCACGTGCTGCTCGACA
CACGGCTGACACGTACCCTGATGGCCGTCGCAGTAGGCTCGAGTCTGGCGGTTGCCGGGGCACTGATGCAGGCGCTGACG
CGCAATCCGCTGGCGTCGCCTGGCCTGTTTGGCATCAATGCCGGCGCGACGTTTGCCATCATCGCCTGTTCGTCGCTGCT
TACACTGTCGTCCATGAGTCAGTGGCTGTGGTGCGCGTTCATCGGCGCTGCGGTGGCGGGCACGATTGTCTGGGTCATCG
GCAACCGGGGGCAGGGCAGCCTCAATCCATTGCGCATCGTATTGGCCGGCGCAGCGATCACCGCCTTGTTCACCGCGTTC
AGCCAGGCCTTGCTGGTGGTCAATCAGGACGGTCTGGACACTGTGCTGTTCTGGCTGGCCGGTTCCTTGTCGGAGCGCGA
ACTGAGCACCGCTGCGCCGTTGCTCGTCTGCGTGGTCATGGGGCTTGCCGGCGCGCTGGTGCTGGCGGGGCAAGTCAACG
TGCTCAACACCGGGGAAGCCATCGCGACGGCGCTGGGCCAGCGTACGGGGCTGATTCGCCTGATGATGAGCGTGGTAATC
ATTGCCCTGGCAGGCAGCGCCGTGGCGCTGGCGGGCAGTATCGGCTTCATAGGTCTGCTGGTGCCACATATGGTGCGCAA
GACGCTGTCCATCGACCATCGCTGGCTGCTGCCTGGCTGCGCAGTGCTGGGCGCGACGCTGTTGTTGCTGGCCGACACGC
TGGCGCGAGTCGTGATCGTCCCTCAGGAAGTCCCGGTGGGTGTGATGACGGCTCTGTTTGGTGCGCCGTTCTTCATTGCA
CTGGTTCGGCGGGGCACGCGCTATGGATAA

Upstream 100 bases:

>100_bases
GGCGCGTCGATGCCATCGCCTGGAGCCTGTCCGGCGGCATTCTGGGCGCCAACCGCATGCTCGATGAGGTCGCTCGCGTG
GCCCTGGCGGATAGCGCCTC

Downstream 100 bases:

>100_bases
GCATTTCACCGTGCGCTACCGGAGCTTTTCCCGGCAGTTCAGCCTGACCGCATTGACGCGCTTGCTTTCGGGCCTGGCGC
TGACGCTGCTGGTCGTACTG

Product: transport system permease protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTAAAKLGLGLLILVACMGLSLATGATWISPADIVRSVWQPDALSAIEHVLLDTRLTRTLMAVAVGSSLAVAGALMQALT
RNPLASPGLFGINAGATFAIIACSSLLTLSSMSQWLWCAFIGAAVAGTIVWVIGNRGQGSLNPLRIVLAGAAITALFTAF
SQALLVVNQDGLDTVLFWLAGSLSERELSTAAPLLVCVVMGLAGALVLAGQVNVLNTGEAIATALGQRTGLIRLMMSVVI
IALAGSAVALAGSIGFIGLLVPHMVRKTLSIDHRWLLPGCAVLGATLLLLADTLARVVIVPQEVPVGVMTALFGAPFFIA
LVRRGTRYG

Sequences:

>Translated_329_residues
MTAAAKLGLGLLILVACMGLSLATGATWISPADIVRSVWQPDALSAIEHVLLDTRLTRTLMAVAVGSSLAVAGALMQALT
RNPLASPGLFGINAGATFAIIACSSLLTLSSMSQWLWCAFIGAAVAGTIVWVIGNRGQGSLNPLRIVLAGAAITALFTAF
SQALLVVNQDGLDTVLFWLAGSLSERELSTAAPLLVCVVMGLAGALVLAGQVNVLNTGEAIATALGQRTGLIRLMMSVVI
IALAGSAVALAGSIGFIGLLVPHMVRKTLSIDHRWLLPGCAVLGATLLLLADTLARVVIVPQEVPVGVMTALFGAPFFIA
LVRRGTRYG
>Mature_328_residues
TAAAKLGLGLLILVACMGLSLATGATWISPADIVRSVWQPDALSAIEHVLLDTRLTRTLMAVAVGSSLAVAGALMQALTR
NPLASPGLFGINAGATFAIIACSSLLTLSSMSQWLWCAFIGAAVAGTIVWVIGNRGQGSLNPLRIVLAGAAITALFTAFS
QALLVVNQDGLDTVLFWLAGSLSERELSTAAPLLVCVVMGLAGALVLAGQVNVLNTGEAIATALGQRTGLIRLMMSVVII
ALAGSAVALAGSIGFIGLLVPHMVRKTLSIDHRWLLPGCAVLGATLLLLADTLARVVIVPQEVPVGVMTALFGAPFFIAL
VRRGTRYG

Specific function: Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=299, Percent_Identity=45.4849498327759, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1790741, Length=302, Percent_Identity=38.0794701986755, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1790740, Length=317, Percent_Identity=35.6466876971609, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788004, Length=306, Percent_Identity=36.2745098039216, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786804, Length=293, Percent_Identity=34.4709897610922, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786347, Length=285, Percent_Identity=30.1754385964912, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33812; Mature: 33681

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAAKLGLGLLILVACMGLSLATGATWISPADIVRSVWQPDALSAIEHVLLDTRLTRTL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MAVAVGSSLAVAGALMQALTRNPLASPGLFGINAGATFAIIACSSLLTLSSMSQWLWCAF
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGAAVAGTIVWVIGNRGQGSLNPLRIVLAGAAITALFTAFSQALLVVNQDGLDTVLFWLA
HHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHH
GSLSERELSTAAPLLVCVVMGLAGALVLAGQVNVLNTGEAIATALGQRTGLIRLMMSVVI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
IALAGSAVALAGSIGFIGLLVPHMVRKTLSIDHRWLLPGCAVLGATLLLLADTLARVVIV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEC
PQEVPVGVMTALFGAPFFIALVRRGTRYG
CCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TAAAKLGLGLLILVACMGLSLATGATWISPADIVRSVWQPDALSAIEHVLLDTRLTRTL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MAVAVGSSLAVAGALMQALTRNPLASPGLFGINAGATFAIIACSSLLTLSSMSQWLWCAF
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGAAVAGTIVWVIGNRGQGSLNPLRIVLAGAAITALFTAFSQALLVVNQDGLDTVLFWLA
HHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHH
GSLSERELSTAAPLLVCVVMGLAGALVLAGQVNVLNTGEAIATALGQRTGLIRLMMSVVI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
IALAGSAVALAGSIGFIGLLVPHMVRKTLSIDHRWLLPGCAVLGATLLLLADTLARVVIV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEC
PQEVPVGVMTALFGAPFFIALVRRGTRYG
CCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8596459 [H]