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The map label for this gene is cbrC [H]

Identifier: 66045828

GI number: 66045828

Start: 3038676

End: 3039707

Strand: Direct

Name: cbrC [H]

Synonym: Psyr_2592

Alternate gene names: 66045828

Gene position: 3038676-3039707 (Clockwise)

Preceding gene: 66045827

Following gene: 66045829

Centisome position: 49.87

GC content: 63.76

Gene sequence:

>1032_bases
ATGGATAAGCATTTCACCGTGCGCTACCGGAGCTTTTCCCGGCAGTTCAGCCTGACCGCATTGACGCGCTTGCTTTCGGG
CCTGGCGCTGACGCTGCTGGTCGTACTGAGCTCGTTGGCCGTGGGCAAGATCAATCTGTCGCCCGCGACCCTGCTGAGTG
TTTTTACCGGTCAGGCAGATGCCAGCCTGGTCTTCATCGTCGAACAGCTGCGCATGCCCCGGCTGGCCCTGGCCGCCCTG
GTCGGCGCAGCACTGGCAGTGTCCGGGCTGATCCTGCAAAGCATCATTCGCAACCCGCTGGCCTCACCTGATCTGTTAGG
CATCACCAGCGGTGCCAGCGCCGCCGCCGTGTTGTACCTGTCATTCTTCTCGGCTGCACTGGGCGCGCAGTTTCTACCCC
TGGCGGCGATCTCCGGCGCAGGCCTCGCGGCACTGGTCATTTATCTGCTGGCCTGGAATCAGGGCGCTTCACCCTTGCGC
ATGGTGTTGATCGGGGTAGGGGTGTCGGCTCTGCTGGCTGCGGTGACCACGTTCATTCTGGTGTTCAGCCCGTTGACCAC
CACCTTGTCGGCTTATGTCTGGCTGACCGGGAGCGTGTATGGTGCCAGTTGGCCAGAGCCCCGCGCGCTGGCCGGCTGGC
TGCTTATGACATTGCCGCTGCTGGCACTGCTCGCCCGTCAGGTGCGCATGCAGCAACTGGATGACGCGCTGGCCCAGGGA
ATCGGCGTGCGCGTGCAATGGCTGCGCGCCGGTTTGCTGTTGGTGAGCGTCGCGCTGGCCGGGCTGGCGGTCGCGTGGGG
CGGGGCGATTGCCTTTGTCGGGCTGATCGCGCCTCATATCGCCAAACGCCTGATGCCGCCGGGGTTCGTGGGGCAAGCGC
TGATGGCGGCGTTGATCGGTGCCAATCTGGTGATGCTTGCCGATCTGGCCGGACGCACGCTGTTCCTGCCGCTGGATCTG
CCCGCAGGGATTTTTGTCGCGGTGCTGGGCACACCGTTTTTTCTGTACCTATTGATCAACCAGCGGCATTAA

Upstream 100 bases:

>100_bases
GCGCGAGTCGTGATCGTCCCTCAGGAAGTCCCGGTGGGTGTGATGACGGCTCTGTTTGGTGCGCCGTTCTTCATTGCACT
GGTTCGGCGGGGCACGCGCT

Downstream 100 bases:

>100_bases
GGAATTACGGATGGCGTCAATCGCAACCCACGACCTGACCCTGAGTTACCAGCGGCAGGTGATCATCGACAGCCTTGATC
TGCAGTTACCCGCAGGCCAG

Product: transport system permease protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDKHFTVRYRSFSRQFSLTALTRLLSGLALTLLVVLSSLAVGKINLSPATLLSVFTGQADASLVFIVEQLRMPRLALAAL
VGAALAVSGLILQSIIRNPLASPDLLGITSGASAAAVLYLSFFSAALGAQFLPLAAISGAGLAALVIYLLAWNQGASPLR
MVLIGVGVSALLAAVTTFILVFSPLTTTLSAYVWLTGSVYGASWPEPRALAGWLLMTLPLLALLARQVRMQQLDDALAQG
IGVRVQWLRAGLLLVSVALAGLAVAWGGAIAFVGLIAPHIAKRLMPPGFVGQALMAALIGANLVMLADLAGRTLFLPLDL
PAGIFVAVLGTPFFLYLLINQRH

Sequences:

>Translated_343_residues
MDKHFTVRYRSFSRQFSLTALTRLLSGLALTLLVVLSSLAVGKINLSPATLLSVFTGQADASLVFIVEQLRMPRLALAAL
VGAALAVSGLILQSIIRNPLASPDLLGITSGASAAAVLYLSFFSAALGAQFLPLAAISGAGLAALVIYLLAWNQGASPLR
MVLIGVGVSALLAAVTTFILVFSPLTTTLSAYVWLTGSVYGASWPEPRALAGWLLMTLPLLALLARQVRMQQLDDALAQG
IGVRVQWLRAGLLLVSVALAGLAVAWGGAIAFVGLIAPHIAKRLMPPGFVGQALMAALIGANLVMLADLAGRTLFLPLDL
PAGIFVAVLGTPFFLYLLINQRH
>Mature_343_residues
MDKHFTVRYRSFSRQFSLTALTRLLSGLALTLLVVLSSLAVGKINLSPATLLSVFTGQADASLVFIVEQLRMPRLALAAL
VGAALAVSGLILQSIIRNPLASPDLLGITSGASAAAVLYLSFFSAALGAQFLPLAAISGAGLAALVIYLLAWNQGASPLR
MVLIGVGVSALLAAVTTFILVFSPLTTTLSAYVWLTGSVYGASWPEPRALAGWLLMTLPLLALLARQVRMQQLDDALAQG
IGVRVQWLRAGLLLVSVALAGLAVAWGGAIAFVGLIAPHIAKRLMPPGFVGQALMAALIGANLVMLADLAGRTLFLPLDL
PAGIFVAVLGTPFFLYLLINQRH

Specific function: Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=302, Percent_Identity=37.0860927152318, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790740, Length=313, Percent_Identity=36.1022364217252, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1790741, Length=277, Percent_Identity=32.8519855595668, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786347, Length=280, Percent_Identity=33.5714285714286, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=32.6315789473684, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=30.9904153354633, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35886; Mature: 35886

Theoretical pI: Translated: 11.33; Mature: 11.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKHFTVRYRSFSRQFSLTALTRLLSGLALTLLVVLSSLAVGKINLSPATLLSVFTGQAD
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
ASLVFIVEQLRMPRLALAALVGAALAVSGLILQSIIRNPLASPDLLGITSGASAAAVLYL
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHH
SFFSAALGAQFLPLAAISGAGLAALVIYLLAWNQGASPLRMVLIGVGVSALLAAVTTFIL
HHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHH
VFSPLTTTLSAYVWLTGSVYGASWPEPRALAGWLLMTLPLLALLARQVRMQQLDDALAQG
HHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGVRVQWLRAGLLLVSVALAGLAVAWGGAIAFVGLIAPHIAKRLMPPGFVGQALMAALIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ANLVMLADLAGRTLFLPLDLPAGIFVAVLGTPFFLYLLINQRH
CHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKHFTVRYRSFSRQFSLTALTRLLSGLALTLLVVLSSLAVGKINLSPATLLSVFTGQAD
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
ASLVFIVEQLRMPRLALAALVGAALAVSGLILQSIIRNPLASPDLLGITSGASAAAVLYL
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHH
SFFSAALGAQFLPLAAISGAGLAALVIYLLAWNQGASPLRMVLIGVGVSALLAAVTTFIL
HHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHH
VFSPLTTTLSAYVWLTGSVYGASWPEPRALAGWLLMTLPLLALLARQVRMQQLDDALAQG
HHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGVRVQWLRAGLLLVSVALAGLAVAWGGAIAFVGLIAPHIAKRLMPPGFVGQALMAALIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ANLVMLADLAGRTLFLPLDLPAGIFVAVLGTPFFLYLLINQRH
CHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8596459 [H]