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The map label for this gene is nahR [H]

Identifier: 66045709

GI number: 66045709

Start: 2866699

End: 2867628

Strand: Reverse

Name: nahR [H]

Synonym: Psyr_2473

Alternate gene names: 66045709

Gene position: 2867628-2866699 (Counterclockwise)

Preceding gene: 66045711

Following gene: 66045708

Centisome position: 47.06

GC content: 60.22

Gene sequence:

>930_bases
ATGAACCTGAACAAGGTCGATCTCAACCTTTTCATTGTCTTCGACGCCATCTACACCGAAGCCAACCTGACCCGCGCCGG
ACAGATTGTCGGCATTACCCAGCCTGCAGTCTCCAACGCACTGGCGCGGCTGCGCGAGACCTTCAACGACCCGCTGTTCG
TGCGCACGGCACAAGGCATGGTGCCGACACCGATGGCGCAGAACATCATCGGCCCGGTGCGCAACGCCCTTTCGTTGCTC
AGGGTATCGGTGCAGGAAAGTCGCATCTTCAACCCGTTGCAGGCCAACAAGAATTACCGCATCAGCATGACCGACCTGAC
CGAGGCAGTGATCCTGCCAGCGCTGTTCCAGCGACTGCGACGCCTGGCGCCTGCGGTGACCATCGAAAGCTTTCTTTCCA
AGCGCCGGGAAACCACCAAGGAACTGGCCGCCGGACGCCTCGACTTCGCTGTGGACGCGCCGCTCAACACTGACCCGCAG
GTGCGCCATGTGAAGCTGATGGAGGACCGCTATGTGTGTGGCATGCGCAAGGGGCATCCATTGGCAAACAAGGCCACGCT
GACCCTCGACGATTACCTGAGCCAGTCTCATATCCATATCTCCAGCCGCCGCAGCGGGTTGGGCCATGTGGATCTGGCGC
TCGGCAAGATGGGCATCCAGCGCAGGATAGCGTTGCGCTCGCAGCACTACATGATGGCAACCCAGGTGCTGCAGCAGACC
GACATGGTCATGACTGTGCCCGAGCGCTTCGCCCGACGTAACGACTTGCACTATGTCTACCTGCCAGTCAGCGACGTTCC
CTCGGTCGAGACCCACCTGTACTGGCATGAAAGCACCGACCAGGATCCGGCCAATCGCTGGATGCGCGAGCAGATCATCG
AACTTTCACAGCGGGTGGTGGCGCAGGAACACAATCTCGAAAAGGCATGA

Upstream 100 bases:

>100_bases
CGTGTATAAACATTCATAACCGATATATGATCCGTCACCATCGCGGCATTACCACCCCTCTAAACAATCAATCACAATAA
CGGCACGAGGCGCCCCATCA

Downstream 100 bases:

>100_bases
AATATTTAACTTAAGTTATTGATTATAAAAACTTAAATAACATAACTTAATGTCGTTTCTAGGTAGCGGGGTGCGACCGC
TCAAGCTCTGGTATCGCCAC

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNLNKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALSLL
RVSVQESRIFNPLQANKNYRISMTDLTEAVILPALFQRLRRLAPAVTIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQ
VRHVKLMEDRYVCGMRKGHPLANKATLTLDDYLSQSHIHISSRRSGLGHVDLALGKMGIQRRIALRSQHYMMATQVLQQT
DMVMTVPERFARRNDLHYVYLPVSDVPSVETHLYWHESTDQDPANRWMREQIIELSQRVVAQEHNLEKA

Sequences:

>Translated_309_residues
MNLNKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALSLL
RVSVQESRIFNPLQANKNYRISMTDLTEAVILPALFQRLRRLAPAVTIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQ
VRHVKLMEDRYVCGMRKGHPLANKATLTLDDYLSQSHIHISSRRSGLGHVDLALGKMGIQRRIALRSQHYMMATQVLQQT
DMVMTVPERFARRNDLHYVYLPVSDVPSVETHLYWHESTDQDPANRWMREQIIELSQRVVAQEHNLEKA
>Mature_309_residues
MNLNKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALSLL
RVSVQESRIFNPLQANKNYRISMTDLTEAVILPALFQRLRRLAPAVTIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQ
VRHVKLMEDRYVCGMRKGHPLANKATLTLDDYLSQSHIHISSRRSGLGHVDLALGKMGIQRRIALRSQHYMMATQVLQQT
DMVMTVPERFARRNDLHYVYLPVSDVPSVETHLYWHESTDQDPANRWMREQIIELSQRVVAQEHNLEKA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=300, Percent_Identity=30.6666666666667, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87081766, Length=289, Percent_Identity=22.1453287197232, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786820, Length=288, Percent_Identity=25.3472222222222, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790147, Length=301, Percent_Identity=24.5847176079734, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789204, Length=231, Percent_Identity=24.6753246753247, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35161; Mature: 35161

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGM
CCCCEEEEEEEEEEEHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCC
VPTPMAQNIIGPVRNALSLLRVSVQESRIFNPLQANKNYRISMTDLTEAVILPALFQRLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHH
RLAPAVTIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQVRHVKLMEDRYVCGMRKGHP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEHHCHHHHCCCCCCC
LANKATLTLDDYLSQSHIHISSRRSGLGHVDLALGKMGIQRRIALRSQHYMMATQVLQQT
CCCCEEEEHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DMVMTVPERFARRNDLHYVYLPVSDVPSVETHLYWHESTDQDPANRWMREQIIELSQRVV
CCEEECHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
AQEHNLEKA
HHHCCCCCC
>Mature Secondary Structure
MNLNKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGM
CCCCEEEEEEEEEEEHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCC
VPTPMAQNIIGPVRNALSLLRVSVQESRIFNPLQANKNYRISMTDLTEAVILPALFQRLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHH
RLAPAVTIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQVRHVKLMEDRYVCGMRKGHP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEHHCHHHHCCCCCCC
LANKATLTLDDYLSQSHIHISSRRSGLGHVDLALGKMGIQRRIALRSQHYMMATQVLQQT
CCCCEEEEHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DMVMTVPERFARRNDLHYVYLPVSDVPSVETHLYWHESTDQDPANRWMREQIIELSQRVV
CCEEECHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
AQEHNLEKA
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]