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The map label for this gene is sohB [H]

Identifier: 66045696

GI number: 66045696

Start: 2847916

End: 2848938

Strand: Direct

Name: sohB [H]

Synonym: Psyr_2460

Alternate gene names: 66045696

Gene position: 2847916-2848938 (Clockwise)

Preceding gene: 66045689

Following gene: 66045699

Centisome position: 46.74

GC content: 58.65

Gene sequence:

>1023_bases
GTGGATTTCGTTGTCGATTACGCAAGTTTTCTGGCCAAGACCGTGACGCTGGTGATCGCCATCGTTGTGGTACTGGTTGC
CATTGCGTCCATGCGTGGCAAGGGCCGTCGCAAGTCGTCCGGACAATTGCAGGTCACCCGGCTCAATGATTTCTATAAGG
GCCTGCGCGAACGGCTTGAGCAGTCATTGCTCGACAAGGAGCACCTCAAGACGCTGCGCAAAGAGCAGGGCAAGGCACTG
AAGAAAGAGAAAAAGCACGCCGAGCCCAAGGCTCGTGTCTACGTGCTGGATTTCGACGGGGACATCAAGGCCTCGGCCAC
TGAAAGCATGCGCCATGAAATCACCGCGCTGCTGACCCTGGCCACCGACAAGGATGAAGTGGTGCTGCGTCTGGAAAGCG
GCGGCGGCATGGTTCACAGCTACGGCCTGGCGTCTTCGCAACTGGCGCGTATTCGTCAGGCGGGTATCCCGCTGACCGTA
TGCATCGACAAGGTCGCTGCCAGTGGTGGTTACATGATGGCGTGCATCGGCAACAAGATCATCAGCGCACCGTTCGCCAT
CCTCGGATCCATTGGCGTGGTGGCACAGCTGCCCAACGTCAATCGCCTGTTGAAAAAGCACGACATCGATTTCGAAGTGC
TGACCGCAGGTGAATACAAGCGCACCCTGACCGTGTTTGGCGAAAACACCGAAAAGGGCCGCGAGAAATTCCAGCAGGAC
CTGGACATCACTCACGACCTGTTCAAGAACTTCGTTGCCAGCTACCGCCCGCAATTGTCCATCGACGAAGTGGCGACGGG
TGAGGTATGGCTGGGCATGGCGGCGGTCGACAAGCTGCTGGTCGATGAACTCAAGACCAGTGACGAGTACCTGGCCGAGC
GGGCCAGGAATGCAGACGTGTTCCACCTGCACTACGTGCAGCGCAAGAGCCTGCAAGAGCGCATGGGCATGGCGGCTGCC
ACCTCAGCGGATCAACTGGCCACCAAGTGGTGGGGACGTTTGACCCAGCAGCGGTTCTGGTAG

Upstream 100 bases:

>100_bases
TTGTAACGGGTCATTGACTGGTGCGCGGCAAAGGGCGTCGGTATGCTGCATTCAGCACAGCCCTTGATTGGTAAGGGCCT
GACACTCATGAGGGATATTC

Downstream 100 bases:

>100_bases
TAGGTGTAGGTGAAAAGCTGACTTGAGTCGAACCCCAAGTCAGCTGAGTGTTACGGAACCGCCGCGTGACGCAGAGCGTC
ACAAACTGCATTCCCGCGCG

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDFVVDYASFLAKTVTLVIAIVVVLVAIASMRGKGRRKSSGQLQVTRLNDFYKGLRERLEQSLLDKEHLKTLRKEQGKAL
KKEKKHAEPKARVYVLDFDGDIKASATESMRHEITALLTLATDKDEVVLRLESGGGMVHSYGLASSQLARIRQAGIPLTV
CIDKVAASGGYMMACIGNKIISAPFAILGSIGVVAQLPNVNRLLKKHDIDFEVLTAGEYKRTLTVFGENTEKGREKFQQD
LDITHDLFKNFVASYRPQLSIDEVATGEVWLGMAAVDKLLVDELKTSDEYLAERARNADVFHLHYVQRKSLQERMGMAAA
TSADQLATKWWGRLTQQRFW

Sequences:

>Translated_340_residues
MDFVVDYASFLAKTVTLVIAIVVVLVAIASMRGKGRRKSSGQLQVTRLNDFYKGLRERLEQSLLDKEHLKTLRKEQGKAL
KKEKKHAEPKARVYVLDFDGDIKASATESMRHEITALLTLATDKDEVVLRLESGGGMVHSYGLASSQLARIRQAGIPLTV
CIDKVAASGGYMMACIGNKIISAPFAILGSIGVVAQLPNVNRLLKKHDIDFEVLTAGEYKRTLTVFGENTEKGREKFQQD
LDITHDLFKNFVASYRPQLSIDEVATGEVWLGMAAVDKLLVDELKTSDEYLAERARNADVFHLHYVQRKSLQERMGMAAA
TSADQLATKWWGRLTQQRFW
>Mature_340_residues
MDFVVDYASFLAKTVTLVIAIVVVLVAIASMRGKGRRKSSGQLQVTRLNDFYKGLRERLEQSLLDKEHLKTLRKEQGKAL
KKEKKHAEPKARVYVLDFDGDIKASATESMRHEITALLTLATDKDEVVLRLESGGGMVHSYGLASSQLARIRQAGIPLTV
CIDKVAASGGYMMACIGNKIISAPFAILGSIGVVAQLPNVNRLLKKHDIDFEVLTAGEYKRTLTVFGENTEKGREKFQQD
LDITHDLFKNFVASYRPQLSIDEVATGEVWLGMAAVDKLLVDELKTSDEYLAERARNADVFHLHYVQRKSLQERMGMAAA
TSADQLATKWWGRLTQQRFW

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=344, Percent_Identity=51.453488372093, Blast_Score=321, Evalue=4e-89,
Organism=Escherichia coli, GI1788064, Length=184, Percent_Identity=29.8913043478261, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 38017; Mature: 38017

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFVVDYASFLAKTVTLVIAIVVVLVAIASMRGKGRRKSSGQLQVTRLNDFYKGLRERLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
QSLLDKEHLKTLRKEQGKALKKEKKHAEPKARVYVLDFDGDIKASATESMRHEITALLTL
HHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEE
ATDKDEVVLRLESGGGMVHSYGLASSQLARIRQAGIPLTVCIDKVAASGGYMMACIGNKI
ECCCCEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCHH
ISAPFAILGSIGVVAQLPNVNRLLKKHDIDFEVLTAGEYKRTLTVFGENTEKGREKFQQD
HHHHHHHHHCHHHHHCCCCHHHHHHHCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHH
LDITHDLFKNFVASYRPQLSIDEVATGEVWLGMAAVDKLLVDELKTSDEYLAERARNADV
HCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCE
FHLHYVQRKSLQERMGMAAATSADQLATKWWGRLTQQRFW
EEEHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFVVDYASFLAKTVTLVIAIVVVLVAIASMRGKGRRKSSGQLQVTRLNDFYKGLRERLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
QSLLDKEHLKTLRKEQGKALKKEKKHAEPKARVYVLDFDGDIKASATESMRHEITALLTL
HHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEE
ATDKDEVVLRLESGGGMVHSYGLASSQLARIRQAGIPLTVCIDKVAASGGYMMACIGNKI
ECCCCEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCHH
ISAPFAILGSIGVVAQLPNVNRLLKKHDIDFEVLTAGEYKRTLTVFGENTEKGREKFQQD
HHHHHHHHHCHHHHHCCCCHHHHHHHCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHH
LDITHDLFKNFVASYRPQLSIDEVATGEVWLGMAAVDKLLVDELKTSDEYLAERARNADV
HCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCE
FHLHYVQRKSLQERMGMAAATSADQLATKWWGRLTQQRFW
EEEHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]