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The map label for this gene is exuT [H]

Identifier: 66045369

GI number: 66045369

Start: 2487543

End: 2488871

Strand: Reverse

Name: exuT [H]

Synonym: Psyr_2129

Alternate gene names: 66045369

Gene position: 2488871-2487543 (Counterclockwise)

Preceding gene: 66045372

Following gene: 66045367

Centisome position: 40.84

GC content: 61.25

Gene sequence:

>1329_bases
ATGCTTAACACCCAGACCAACCCTGTCGCCCAGGCCGCCCGTGCCGGGATGGGCGAAAAGATCCGCGGCGCACTCGCCGT
CGGCAAGACTCGCTGGGGCATGCTCGCCCTGGTGTTCTTCGCCACTACGCTGAACTACATCGACCGTGCCGCGCTCGGCG
TCATGCAGCCCATCCTAGCCAAGGAAATGAGCTGGACGGCGATGGACTACGCCAACATCAACTTCTGGTTTCAGGTGGGT
TACGCGGTCGGCTTTGTGCTGCAGGGCCGCTTCATCGACAAGGTCGGCGTGAAGCGTGCATTCTTCCTCGCGGTGCTGCT
GTGGAGCCTGGCGACCGGTGCTCACGGCCTGGCCACTTCCGCCGTCGGCTTCATGGTCTGCCGCTTCATTCTGGGCCTGA
CCGAAGCCGCCAATTACCCGGCCTGTGTGAAGACCACGCGGCTGTGGTTCCCTGCCGGTGAGCGTGCAGTGGCCACCGGT
ATCTTCAACGCCGGCACCAACGTTGGTGCCATGCTGACCCCGGCCCTGCTGCCGGTGATCCTCACGGTCTGGGGCTGGCA
GGCCGCCTTCGTGGCGATGGGTTCGCTGGGGCTGCTCTGGGCTATCACCTGGCGCCTGAAGTACTACAACCCCGAAGAGC
ATCCGACCGTCAGCAAGACCGAGCTGGATTACATCAATCAGGAAGTCGAACCGGCTCCGGTCAAGGTGCCATTCACCGGC
ATTCTGAAGATGCGTGGCACATGGGCGTTCGCGCTGGCGTATGCGATCACTGCTCCGGTGTTCTGGTTTTACCTGTACTG
GCTGCCGCCGTTCCTCAATCAGCAATACAACCTGGGGATCAGCGTGACGCAGATGGGTGTTCCGCTGATTCTGATCTGGC
TGACGGCCGATTTCGGCAGTGTCGGTGGCGGTATCCTGTCGTCCTGGCTGATTGGTCGTGGCATGCGTGCGACGACTGCG
CGGCTGTTGTCGATGCTGATCTTTGCCATCACGATCTGCAGCGTGGTGTTCGCCGCCAATGCCAGCGGGCTGTGGGTAGC
GGTACTGGCCATTTCGCTTGCCGTGGGTGCGCATCAGGCCTGGACGGCGAATATCTGGAGCCTGGTGATGGACTACACCC
CCAAGCACATGATGAGTACCGTGTTCGGCTTCGGCGGCATGTGTGCGGCCATCGGCGGTATGTTCATGACGCAGATCGTG
GGTGCGGTGCTGACCGCCACCAATAACAACTACAACGTGTTGTTCACGATGATCCCGGCGATGTATTTCATTGCCCTGAT
CTGGATGTACTTCATGGCCCCTCGCAAGGTTCCGACGCTCAGCGAGTAA

Upstream 100 bases:

>100_bases
TTCTACGACTTCACTTTACCTGCACAACGCCTGCATCGAGTGGACTTCTCAGTCCGACTGTTGCCAGCAGCACAGTCCTG
GAACGGATGGTTAGAACATC

Downstream 100 bases:

>100_bases
TCGTCTGACGCAGCCCGAAAACCCAGAGTGGCTATCGTCCCCACGCTCCGTGTGGGGATGCAGTTCGTTACGCTCTGCGT
CACACAGCGGGTTTTCTTTG

Product: major facilitator transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLNTQTNPVAQAARAGMGEKIRGALAVGKTRWGMLALVFFATTLNYIDRAALGVMQPILAKEMSWTAMDYANINFWFQVG
YAVGFVLQGRFIDKVGVKRAFFLAVLLWSLATGAHGLATSAVGFMVCRFILGLTEAANYPACVKTTRLWFPAGERAVATG
IFNAGTNVGAMLTPALLPVILTVWGWQAAFVAMGSLGLLWAITWRLKYYNPEEHPTVSKTELDYINQEVEPAPVKVPFTG
ILKMRGTWAFALAYAITAPVFWFYLYWLPPFLNQQYNLGISVTQMGVPLILIWLTADFGSVGGGILSSWLIGRGMRATTA
RLLSMLIFAITICSVVFAANASGLWVAVLAISLAVGAHQAWTANIWSLVMDYTPKHMMSTVFGFGGMCAAIGGMFMTQIV
GAVLTATNNNYNVLFTMIPAMYFIALIWMYFMAPRKVPTLSE

Sequences:

>Translated_442_residues
MLNTQTNPVAQAARAGMGEKIRGALAVGKTRWGMLALVFFATTLNYIDRAALGVMQPILAKEMSWTAMDYANINFWFQVG
YAVGFVLQGRFIDKVGVKRAFFLAVLLWSLATGAHGLATSAVGFMVCRFILGLTEAANYPACVKTTRLWFPAGERAVATG
IFNAGTNVGAMLTPALLPVILTVWGWQAAFVAMGSLGLLWAITWRLKYYNPEEHPTVSKTELDYINQEVEPAPVKVPFTG
ILKMRGTWAFALAYAITAPVFWFYLYWLPPFLNQQYNLGISVTQMGVPLILIWLTADFGSVGGGILSSWLIGRGMRATTA
RLLSMLIFAITICSVVFAANASGLWVAVLAISLAVGAHQAWTANIWSLVMDYTPKHMMSTVFGFGGMCAAIGGMFMTQIV
GAVLTATNNNYNVLFTMIPAMYFIALIWMYFMAPRKVPTLSE
>Mature_442_residues
MLNTQTNPVAQAARAGMGEKIRGALAVGKTRWGMLALVFFATTLNYIDRAALGVMQPILAKEMSWTAMDYANINFWFQVG
YAVGFVLQGRFIDKVGVKRAFFLAVLLWSLATGAHGLATSAVGFMVCRFILGLTEAANYPACVKTTRLWFPAGERAVATG
IFNAGTNVGAMLTPALLPVILTVWGWQAAFVAMGSLGLLWAITWRLKYYNPEEHPTVSKTELDYINQEVEPAPVKVPFTG
ILKMRGTWAFALAYAITAPVFWFYLYWLPPFLNQQYNLGISVTQMGVPLILIWLTADFGSVGGGILSSWLIGRGMRATTA
RLLSMLIFAITICSVVFAANASGLWVAVLAISLAVGAHQAWTANIWSLVMDYTPKHMMSTVFGFGGMCAAIGGMFMTQIV
GAVLTATNNNYNVLFTMIPAMYFIALIWMYFMAPRKVPTLSE

Specific function: Aldohexuronate transport system [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=380, Percent_Identity=23.9473684210526, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI9966811, Length=385, Percent_Identity=22.8571428571429, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI9945322, Length=397, Percent_Identity=25.6926952141058, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI21322234, Length=372, Percent_Identity=25.2688172043011, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI2367193, Length=392, Percent_Identity=29.3367346938776, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789515, Length=440, Percent_Identity=26.1363636363636, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI2367379, Length=417, Percent_Identity=26.6187050359712, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789152, Length=405, Percent_Identity=26.6666666666667, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082320, Length=387, Percent_Identity=27.906976744186, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17535049, Length=408, Percent_Identity=24.5098039215686, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115533556, Length=459, Percent_Identity=24.8366013071895, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI115533554, Length=399, Percent_Identity=25.5639097744361, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554148, Length=397, Percent_Identity=24.1813602015113, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17552542, Length=308, Percent_Identity=25.974025974026, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=359, Percent_Identity=23.9554317548747, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=359, Percent_Identity=23.9554317548747, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920686, Length=379, Percent_Identity=23.2189973614776, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24583789, Length=308, Percent_Identity=26.2987012987013, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI20129235, Length=368, Percent_Identity=27.1739130434783, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648416, Length=318, Percent_Identity=26.7295597484277, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356189, Length=318, Percent_Identity=26.7295597484277, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI62484226, Length=313, Percent_Identity=25.5591054313099, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641682, Length=270, Percent_Identity=25.1851851851852, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573708, Length=393, Percent_Identity=23.4096692111959, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573707, Length=393, Percent_Identity=23.4096692111959, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584153, Length=357, Percent_Identity=22.96918767507, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281361682, Length=235, Percent_Identity=25.1063829787234, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48361; Mature: 48361

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTQTNPVAQAARAGMGEKIRGALAVGKTRWGMLALVFFATTLNYIDRAALGVMQPILA
CCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEMSWTAMDYANINFWFQVGYAVGFVLQGRFIDKVGVKRAFFLAVLLWSLATGAHGLATS
HHCCCCEECCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AVGFMVCRFILGLTEAANYPACVKTTRLWFPAGERAVATGIFNAGTNVGAMLTPALLPVI
HHHHHHHHHHHHHHHCCCCCHHHHEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
LTVWGWQAAFVAMGSLGLLWAITWRLKYYNPEEHPTVSKTELDYINQEVEPAPVKVPFTG
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHCCCCCCCCEECCHHH
ILKMRGTWAFALAYAITAPVFWFYLYWLPPFLNQQYNLGISVTQMGVPLILIWLTADFGS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCEEEEHHCCCEEEEEEECCCCC
VGGGILSSWLIGRGMRATTARLLSMLIFAITICSVVFAANASGLWVAVLAISLAVGAHQA
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHH
WTANIWSLVMDYTPKHMMSTVFGFGGMCAAIGGMFMTQIVGAVLTATNNNYNVLFTMIPA
HHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHH
MYFIALIWMYFMAPRKVPTLSE
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLNTQTNPVAQAARAGMGEKIRGALAVGKTRWGMLALVFFATTLNYIDRAALGVMQPILA
CCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEMSWTAMDYANINFWFQVGYAVGFVLQGRFIDKVGVKRAFFLAVLLWSLATGAHGLATS
HHCCCCEECCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AVGFMVCRFILGLTEAANYPACVKTTRLWFPAGERAVATGIFNAGTNVGAMLTPALLPVI
HHHHHHHHHHHHHHHCCCCCHHHHEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
LTVWGWQAAFVAMGSLGLLWAITWRLKYYNPEEHPTVSKTELDYINQEVEPAPVKVPFTG
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHCCCCCCCCEECCHHH
ILKMRGTWAFALAYAITAPVFWFYLYWLPPFLNQQYNLGISVTQMGVPLILIWLTADFGS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCEEEEHHCCCEEEEEEECCCCC
VGGGILSSWLIGRGMRATTARLLSMLIFAITICSVVFAANASGLWVAVLAISLAVGAHQA
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHH
WTANIWSLVMDYTPKHMMSTVFGFGGMCAAIGGMFMTQIVGAVLTATNNNYNVLFTMIPA
HHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHH
MYFIALIWMYFMAPRKVPTLSE
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]