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The map label for this gene is pabB [H]

Identifier: 66045320

GI number: 66045320

Start: 2424907

End: 2426250

Strand: Reverse

Name: pabB [H]

Synonym: Psyr_2080

Alternate gene names: 66045320

Gene position: 2426250-2424907 (Counterclockwise)

Preceding gene: 66045321

Following gene: 66045318

Centisome position: 39.82

GC content: 63.69

Gene sequence:

>1344_bases
ATGCCGATCTGCTCGATACACCCCCTGCCCTACAGCGCCGACCCGATCGCGTTCTTCGCGCGAATCCGCGAAGCGCCGGG
TGCGGTGCTGCTCGATAGCGGCAGGCCGGCAGCCGTGCGGGGCCGACATGACCTGCTCAGTGCATGGCCGTTGCAGGAAC
TGACCGTCGCCGATGGTGAGAACGGAGCGACCTATCTCCAGCGCTTGCGCGACAGTCTCAAGGCCCTCGGCCCAGCACAG
CTACCTGACGGGTGCGAGCTGCCCTTCGCTGGCGGCCTGATCGGTTATCTGAGCTATGAGTTTGGTCGACGCCTGGAGCC
TTTGCCGGATCAGGCCATTGATGACCTGCAACTGCCCGAGGCCCGTCTGGGGCTCTACGCCTGGGCGCTGATCAGTGATC
ATCAGGAGCAGACCAGCCAGCTGATTTTTCATCCGTCCCTGGCCGTAAGCGAACGCGAACGGCTGATTGAGCTGTTCTCT
GTCGATATCCCTGAGCCGCGCACGGAGTTCCGTCTCAGCCAGCCGTTTCAGGCCAGTATCAGCGCGGATAACTATCGCCA
GGCGTTCGAACGAATTCAGGCCTACATCCAGGCCGGTGACTGCTACCAGGTCAACTTTGCACAACGCTTTCAGGCGCAGT
GCGTCGGTGACCCATGGGCCGCCTATCGTGCGCTGCGAGCGGCTTGTCCGACGCCATTCGCCGGCTACCTGAGCCTGCCG
GGGGCCGATGCAATGCTGAGTCTTTCTCCCGAGCGCTTTGTGCGGGTCAGCACCCGGCAGGTCGAAACCCGCCCGATCAA
AGGCACACGGCCGCGTAGCGCGGACCCGGCGCAGGATGCCGCCTTGGCCGCCGAACTGCTGGCCAGCGAGAAGGACCGCG
CAGAAAACCTGATGATCGTCGACCTGCTGCGCAACGACCTGGGCCGCAGCTGCCGCATCGGCTCGGTGAAAGTCCCAGAG
CTGTTCAGCCTGGAAAGCTACCCCAACGTGCACCATCTGGTGAGCAGCGTGACCGGGGAGCTGGCCGCCGGCAACGATGC
ACTGGACCTGATCGGCGGCAGCTTTCCTGGCGGATCCATCACGGGCGCGCCGAAGATCCGCGCCATGCAGATCATCGACG
AGCTGGAGCCGACCCGCCGCAGCCTGTATTGCGGTTCGTTGATGTACCTGGACGTGCGTGGCGAAATGGACAGCTCGATC
GCCATCCGCAGCCTGCTGGTCAAGGACGGACAGATTTCCTGCTGGGGCGGTGGCGGCATCGTCGCCGACTCGGACTGCGA
GGCGGAATATCAGGAAACCTTCACCAAAGTCCGTGTACTGCTGGAGACGCTTGAAGCACTGTGA

Upstream 100 bases:

>100_bases
GTTCGGTCATGTGCCCGGCGTCTGAACCGACATACCGCTAGGACTGCCGCATCGGCAAGGCTACAATCGCCAGCCGCGTT
TCCAAGGCCGATATTCGACG

Downstream 100 bases:

>100_bases
ACCGCTCTGCGTTGCAAAGAGGACGCAGAGCGTCCAGAACGGCATACCGACGCAGAGCGTCGGCACGATAGCCAGATCAT
TTCGTGACGCTCTGCGTCAC

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPICSIHPLPYSADPIAFFARIREAPGAVLLDSGRPAAVRGRHDLLSAWPLQELTVADGENGATYLQRLRDSLKALGPAQ
LPDGCELPFAGGLIGYLSYEFGRRLEPLPDQAIDDLQLPEARLGLYAWALISDHQEQTSQLIFHPSLAVSERERLIELFS
VDIPEPRTEFRLSQPFQASISADNYRQAFERIQAYIQAGDCYQVNFAQRFQAQCVGDPWAAYRALRAACPTPFAGYLSLP
GADAMLSLSPERFVRVSTRQVETRPIKGTRPRSADPAQDAALAAELLASEKDRAENLMIVDLLRNDLGRSCRIGSVKVPE
LFSLESYPNVHHLVSSVTGELAAGNDALDLIGGSFPGGSITGAPKIRAMQIIDELEPTRRSLYCGSLMYLDVRGEMDSSI
AIRSLLVKDGQISCWGGGGIVADSDCEAEYQETFTKVRVLLETLEAL

Sequences:

>Translated_447_residues
MPICSIHPLPYSADPIAFFARIREAPGAVLLDSGRPAAVRGRHDLLSAWPLQELTVADGENGATYLQRLRDSLKALGPAQ
LPDGCELPFAGGLIGYLSYEFGRRLEPLPDQAIDDLQLPEARLGLYAWALISDHQEQTSQLIFHPSLAVSERERLIELFS
VDIPEPRTEFRLSQPFQASISADNYRQAFERIQAYIQAGDCYQVNFAQRFQAQCVGDPWAAYRALRAACPTPFAGYLSLP
GADAMLSLSPERFVRVSTRQVETRPIKGTRPRSADPAQDAALAAELLASEKDRAENLMIVDLLRNDLGRSCRIGSVKVPE
LFSLESYPNVHHLVSSVTGELAAGNDALDLIGGSFPGGSITGAPKIRAMQIIDELEPTRRSLYCGSLMYLDVRGEMDSSI
AIRSLLVKDGQISCWGGGGIVADSDCEAEYQETFTKVRVLLETLEAL
>Mature_446_residues
PICSIHPLPYSADPIAFFARIREAPGAVLLDSGRPAAVRGRHDLLSAWPLQELTVADGENGATYLQRLRDSLKALGPAQL
PDGCELPFAGGLIGYLSYEFGRRLEPLPDQAIDDLQLPEARLGLYAWALISDHQEQTSQLIFHPSLAVSERERLIELFSV
DIPEPRTEFRLSQPFQASISADNYRQAFERIQAYIQAGDCYQVNFAQRFQAQCVGDPWAAYRALRAACPTPFAGYLSLPG
ADAMLSLSPERFVRVSTRQVETRPIKGTRPRSADPAQDAALAAELLASEKDRAENLMIVDLLRNDLGRSCRIGSVKVPEL
FSLESYPNVHHLVSSVTGELAAGNDALDLIGGSFPGGSITGAPKIRAMQIIDELEPTRRSLYCGSLMYLDVRGEMDSSIA
IRSLLVKDGQISCWGGGGIVADSDCEAEYQETFTKVRVLLETLEAL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=441, Percent_Identity=46.9387755102041, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI1787518, Length=383, Percent_Identity=33.1592689295039, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1786809, Length=220, Percent_Identity=28.6363636363636, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082077, Length=223, Percent_Identity=28.6995515695067, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320935, Length=430, Percent_Identity=32.7906976744186, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=402, Percent_Identity=28.6069651741293, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 48966; Mature: 48835

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPICSIHPLPYSADPIAFFARIREAPGAVLLDSGRPAAVRGRHDLLSAWPLQELTVADGE
CCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEECCCHHHHHHCCCCCEEECCCC
NGATYLQRLRDSLKALGPAQLPDGCELPFAGGLIGYLSYEFGRRLEPLPDQAIDDLQLPE
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCH
ARLGLYAWALISDHQEQTSQLIFHPSLAVSERERLIELFSVDIPEPRTEFRLSQPFQASI
HHHHHHHHHHHHCHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCC
SADNYRQAFERIQAYIQAGDCYQVNFAQRFQAQCVGDPWAAYRALRAACPTPFAGYLSLP
CCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
GADAMLSLSPERFVRVSTRQVETRPIKGTRPRSADPAQDAALAAELLASEKDRAENLMIV
CCCCEEECCHHHHEEEHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCEEHH
DLLRNDLGRSCRIGSVKVPELFSLESYPNVHHLVSSVTGELAAGNDALDLIGGSFPGGSI
HHHHHHCCCCEECCCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCC
TGAPKIRAMQIIDELEPTRRSLYCGSLMYLDVRGEMDSSIAIRSLLVKDGQISCWGGGGI
CCCCCHHHHHHHHHCCHHHHHEEECEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCE
VADSDCEAEYQETFTKVRVLLETLEAL
EECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PICSIHPLPYSADPIAFFARIREAPGAVLLDSGRPAAVRGRHDLLSAWPLQELTVADGE
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEECCCHHHHHHCCCCCEEECCCC
NGATYLQRLRDSLKALGPAQLPDGCELPFAGGLIGYLSYEFGRRLEPLPDQAIDDLQLPE
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCH
ARLGLYAWALISDHQEQTSQLIFHPSLAVSERERLIELFSVDIPEPRTEFRLSQPFQASI
HHHHHHHHHHHHCHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCC
SADNYRQAFERIQAYIQAGDCYQVNFAQRFQAQCVGDPWAAYRALRAACPTPFAGYLSLP
CCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
GADAMLSLSPERFVRVSTRQVETRPIKGTRPRSADPAQDAALAAELLASEKDRAENLMIV
CCCCEEECCHHHHEEEHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCEEHH
DLLRNDLGRSCRIGSVKVPELFSLESYPNVHHLVSSVTGELAAGNDALDLIGGSFPGGSI
HHHHHHCCCCEECCCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCC
TGAPKIRAMQIIDELEPTRRSLYCGSLMYLDVRGEMDSSIAIRSLLVKDGQISCWGGGGI
CCCCCHHHHHHHHHCCHHHHHEEECEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCE
VADSDCEAEYQETFTKVRVLLETLEAL
EECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]