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The map label for this gene is htpG [H]

Identifier: 66045257

GI number: 66045257

Start: 2340585

End: 2342498

Strand: Direct

Name: htpG [H]

Synonym: Psyr_2017

Alternate gene names: 66045257

Gene position: 2340585-2342498 (Clockwise)

Preceding gene: 66045255

Following gene: 66045258

Centisome position: 38.41

GC content: 57.58

Gene sequence:

>1914_bases
ATGATTATGAGTGTGGAAACTCAAAAGGAAACCCTGGGCTTCCAGACCGAGGTAAAGCAACTGCTGCACCTCATGATCCA
TTCGCTGTATTCCAACAAGGAAATTTTCCTTCGCGAATTGATCTCGAACGCGTCTGACGCGGTCGACAAATTGCGTTTTG
AAGCGTTGTCCAAGCCCGAGTTGCTGGAAGGCGGCGCGGAGCTGAAAATTCGTGTGAGCTTCGACAAGGACGCGAAGACC
GTTACGCTTGAAGACAACGGCATCGGTATGAGCCGTGAAGACGTGATCACCCACCTGGGCACGATCGCCAAGTCCGGCAC
CGCCGATTTCATGAAAAACCTGTCGGGCGACCAGAAGAAGGACTCGCACCTGATCGGTCAGTTCGGTGTCGGCTTCTACT
CGGCGTTCATCGTTGCCGATCAGGTCGAAGTGTTCAGCCGTCGTGCCGGCACGCCAGCGAGCGAAGGTGTGCACTGGTCT
TCCAAGGGCGAAGGCGAGTTCGAAGTCGCCACCGTCGACAAGGCTGATCGTGGCACCCGTATTGTTCTGCACCTGAAAAA
CGGTGAAGAGGAATTCGCTGACGGCTACCGCCTGCGCAACATCATCAAGAAATACTCCGACCATATCGCCTTGCCGATCG
AGCTGCCCAAAGAGCAGGCTCCGGCAGCCGAAGGCGAGGAGCCTGCGGCGCTGGAATGGGAAACCGTCAACCGCGCCAGC
GCGCTCTGGACCCGTCCGCGCACCGAGGTGAAGGACGAGGAGTACCAGGAGTTCTACAAGCACGTCGCGCACGACTACGA
GAACCCGCTGAGCTGGAGCCATAACAAGGTCGAAGGCAAGCTGGAATACACCTCGCTGCTGTACGTGCCTGCGCGTGCGC
CGTTTGATCTGTATCAGCGCGAAGCACCGCGTGGTCTCAAGCTCTACGTGCAGCGCGTGTTCGTGATGGATCAGGCCGAG
TCGTTCCTGCCGCTGTACATGCGCTTCGTCAAGGGCGTGGTCGACTCCAATGACCTGTCGCTGAACGTTTCCCGCGAAAT
CCTGCAGAAAGACCCGATCATCGACTCGATGAAGTCGGCGCTGACCAAGCGCGTGCTGGACATGCTGGAGAAGCTGGCGA
AAAACGAGCCCGAGAAGTACAAGGGCTTCTGGAAAAACTTCGGTCAGGTCCTCAAGGAAGGTCCGGCAGAAGACTTCGCC
AACAAGGAAAAAATCGCCGGTCTGCTGCGTTTCGCGTCGACGTCCGACGACAGCGGCGAACAGAGCGTTTCCCTGGCCGA
GTACCTGGCGCGCGCCAAGGAAGGTCAGGACAAGATTTACTACCTCACTGGCGAATCCTACGCACAGGTCAAGAACAGCC
CGCACCTTGAGGTCTTCCGCAAGAAAGGCATTGAAGTGCTGTTGCTCACCGATCGTATCGACGAGTGGCTGATGAGCTAC
CTGAGCGATTTCGATGGCAAGGGCTTTGTGGATGTGGCGCGTGGTGACCTGGACCTGGGCAATCTCGACTCCGAAGAGGA
CAAGAAGGCTCAGGAAGAGATCGCCAAGGACAAGGAAGGCCTGATCGAGCGTCTGAAAGCCGCCTTGGGTGAGTCGGTAA
GCGAAGTGCGGGTTTCCCATCGCCTGACCGATTCGCCTGCAATTCTGGCCATTGGCGAGCAGGATATGGGTCTGCAGATG
CGTCAGATTCTGGAAGCCAGCGGGCAAAAGGTGCCGGATTCCAAGCCTATCTTCGAATTCAACCCTGCCCACCCGTTGAT
CGGCAAGCTCGATGCCGAACAGAGCGAAGACCGCTTCGGCGATCTGTCGCACATTCTGTTCGATCAGGCTGCGCTGGCCG
CTGGTGACAGCCTCAAGGATCCGGCCGCTTACGTGCGTCGTCTGAACAAGTTGCTGGTAGAACTGTCGGTTTGA

Upstream 100 bases:

>100_bases
CTCTTGAAATCCCCGACCCAGCCCCCACCTTGATGACTACCCGCTGTCACACAGGCTGCTGCCTGACCGTGACGGCTTAT
ACCATCCAGATCGGAGTTTG

Downstream 100 bases:

>100_bases
TAGCCGGTTGACAAGAAACCCGCCTCGGCGGGTTTTTTGTTTCAGTTCCCGCGACACGTCTTTCATTTCTCCAACGATCA
GGAGTCAGTAATGAGCAGCA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MIMSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALSKPELLEGGAELKIRVSFDKDAKT
VTLEDNGIGMSREDVITHLGTIAKSGTADFMKNLSGDQKKDSHLIGQFGVGFYSAFIVADQVEVFSRRAGTPASEGVHWS
SKGEGEFEVATVDKADRGTRIVLHLKNGEEEFADGYRLRNIIKKYSDHIALPIELPKEQAPAAEGEEPAALEWETVNRAS
ALWTRPRTEVKDEEYQEFYKHVAHDYENPLSWSHNKVEGKLEYTSLLYVPARAPFDLYQREAPRGLKLYVQRVFVMDQAE
SFLPLYMRFVKGVVDSNDLSLNVSREILQKDPIIDSMKSALTKRVLDMLEKLAKNEPEKYKGFWKNFGQVLKEGPAEDFA
NKEKIAGLLRFASTSDDSGEQSVSLAEYLARAKEGQDKIYYLTGESYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSY
LSDFDGKGFVDVARGDLDLGNLDSEEDKKAQEEIAKDKEGLIERLKAALGESVSEVRVSHRLTDSPAILAIGEQDMGLQM
RQILEASGQKVPDSKPIFEFNPAHPLIGKLDAEQSEDRFGDLSHILFDQAALAAGDSLKDPAAYVRRLNKLLVELSV

Sequences:

>Translated_637_residues
MIMSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALSKPELLEGGAELKIRVSFDKDAKT
VTLEDNGIGMSREDVITHLGTIAKSGTADFMKNLSGDQKKDSHLIGQFGVGFYSAFIVADQVEVFSRRAGTPASEGVHWS
SKGEGEFEVATVDKADRGTRIVLHLKNGEEEFADGYRLRNIIKKYSDHIALPIELPKEQAPAAEGEEPAALEWETVNRAS
ALWTRPRTEVKDEEYQEFYKHVAHDYENPLSWSHNKVEGKLEYTSLLYVPARAPFDLYQREAPRGLKLYVQRVFVMDQAE
SFLPLYMRFVKGVVDSNDLSLNVSREILQKDPIIDSMKSALTKRVLDMLEKLAKNEPEKYKGFWKNFGQVLKEGPAEDFA
NKEKIAGLLRFASTSDDSGEQSVSLAEYLARAKEGQDKIYYLTGESYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSY
LSDFDGKGFVDVARGDLDLGNLDSEEDKKAQEEIAKDKEGLIERLKAALGESVSEVRVSHRLTDSPAILAIGEQDMGLQM
RQILEASGQKVPDSKPIFEFNPAHPLIGKLDAEQSEDRFGDLSHILFDQAALAAGDSLKDPAAYVRRLNKLLVELSV
>Mature_637_residues
MIMSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALSKPELLEGGAELKIRVSFDKDAKT
VTLEDNGIGMSREDVITHLGTIAKSGTADFMKNLSGDQKKDSHLIGQFGVGFYSAFIVADQVEVFSRRAGTPASEGVHWS
SKGEGEFEVATVDKADRGTRIVLHLKNGEEEFADGYRLRNIIKKYSDHIALPIELPKEQAPAAEGEEPAALEWETVNRAS
ALWTRPRTEVKDEEYQEFYKHVAHDYENPLSWSHNKVEGKLEYTSLLYVPARAPFDLYQREAPRGLKLYVQRVFVMDQAE
SFLPLYMRFVKGVVDSNDLSLNVSREILQKDPIIDSMKSALTKRVLDMLEKLAKNEPEKYKGFWKNFGQVLKEGPAEDFA
NKEKIAGLLRFASTSDDSGEQSVSLAEYLARAKEGQDKIYYLTGESYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSY
LSDFDGKGFVDVARGDLDLGNLDSEEDKKAQEEIAKDKEGLIERLKAALGESVSEVRVSHRLTDSPAILAIGEQDMGLQM
RQILEASGQKVPDSKPIFEFNPAHPLIGKLDAEQSEDRFGDLSHILFDQAALAAGDSLKDPAAYVRRLNKLLVELSV

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=685, Percent_Identity=37.5182481751825, Blast_Score=429, Evalue=1e-120,
Organism=Homo sapiens, GI4507677, Length=689, Percent_Identity=36.2844702467344, Blast_Score=414, Evalue=1e-115,
Organism=Homo sapiens, GI155722983, Length=635, Percent_Identity=36.5354330708661, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI154146191, Length=413, Percent_Identity=38.0145278450363, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI153792590, Length=413, Percent_Identity=38.0145278450363, Blast_Score=268, Evalue=1e-71,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=60.48, Blast_Score=792, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=670, Percent_Identity=37.7611940298507, Blast_Score=444, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=680, Percent_Identity=36.3235294117647, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=659, Percent_Identity=34.9013657056146, Blast_Score=356, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI115535167, Length=444, Percent_Identity=37.1621621621622, Blast_Score=285, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6323840, Length=677, Percent_Identity=38.4047267355982, Blast_Score=447, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6325016, Length=681, Percent_Identity=37.8854625550661, Blast_Score=442, Evalue=1e-125,
Organism=Drosophila melanogaster, GI17647529, Length=690, Percent_Identity=37.6811594202899, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI21357739, Length=676, Percent_Identity=37.4260355029586, Blast_Score=410, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24586016, Length=649, Percent_Identity=35.1309707241911, Blast_Score=375, Evalue=1e-104,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71577; Mature: 71577

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00018 EF_HAND_1 ; PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALSKPE
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LLEGGAELKIRVSFDKDAKTVTLEDNGIGMSREDVITHLGTIAKSGTADFMKNLSGDQKK
HHCCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCH
DSHLIGQFGVGFYSAFIVADQVEVFSRRAGTPASEGVHWSSKGEGEFEVATVDKADRGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCE
IVLHLKNGEEEFADGYRLRNIIKKYSDHIALPIELPKEQAPAAEGEEPAALEWETVNRAS
EEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHH
ALWTRPRTEVKDEEYQEFYKHVAHDYENPLSWSHNKVEGKLEYTSLLYVPARAPFDLYQR
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHH
EAPRGLKLYVQRVFVMDQAESFLPLYMRFVKGVVDSNDLSLNVSREILQKDPIIDSMKSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCHHHHHHH
LTKRVLDMLEKLAKNEPEKYKGFWKNFGQVLKEGPAEDFANKEKIAGLLRFASTSDDSGE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCCH
QSVSLAEYLARAKEGQDKIYYLTGESYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSY
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCHHHHHHCCCEEEEEHHHHHHHHHHH
LSDFDGKGFVDVARGDLDLGNLDSEEDKKAQEEIAKDKEGLIERLKAALGESVSEVRVSH
HHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RLTDSPAILAIGEQDMGLQMRQILEASGQKVPDSKPIFEFNPAHPLIGKLDAEQSEDRFG
HCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHH
DLSHILFDQAALAAGDSLKDPAAYVRRLNKLLVELSV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIMSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALSKPE
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LLEGGAELKIRVSFDKDAKTVTLEDNGIGMSREDVITHLGTIAKSGTADFMKNLSGDQKK
HHCCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCH
DSHLIGQFGVGFYSAFIVADQVEVFSRRAGTPASEGVHWSSKGEGEFEVATVDKADRGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCE
IVLHLKNGEEEFADGYRLRNIIKKYSDHIALPIELPKEQAPAAEGEEPAALEWETVNRAS
EEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHH
ALWTRPRTEVKDEEYQEFYKHVAHDYENPLSWSHNKVEGKLEYTSLLYVPARAPFDLYQR
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHH
EAPRGLKLYVQRVFVMDQAESFLPLYMRFVKGVVDSNDLSLNVSREILQKDPIIDSMKSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCHHHHHHH
LTKRVLDMLEKLAKNEPEKYKGFWKNFGQVLKEGPAEDFANKEKIAGLLRFASTSDDSGE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCCH
QSVSLAEYLARAKEGQDKIYYLTGESYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSY
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCHHHHHHCCCEEEEEHHHHHHHHHHH
LSDFDGKGFVDVARGDLDLGNLDSEEDKKAQEEIAKDKEGLIERLKAALGESVSEVRVSH
HHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RLTDSPAILAIGEQDMGLQMRQILEASGQKVPDSKPIFEFNPAHPLIGKLDAEQSEDRFG
HCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHH
DLSHILFDQAALAAGDSLKDPAAYVRRLNKLLVELSV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA