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The map label for this gene is syrD [H]

Identifier: 66045203

GI number: 66045203

Start: 2273616

End: 2275292

Strand: Reverse

Name: syrD [H]

Synonym: Psyr_1963

Alternate gene names: 66045203

Gene position: 2275292-2273616 (Counterclockwise)

Preceding gene: 66045204

Following gene: 66045202

Centisome position: 37.34

GC content: 62.67

Gene sequence:

>1677_bases
ATGACCCGCACAACTGAAAGCCTCGCCCGGGAAACCCTGAGAATCCTCAAGCCGTTCTGGTGGCTGGTGGCGCTGTCGAC
CTTGCTGGGGATTGTCAGCGGCCTGAGCGTCACCGGCCTGCTGGCCACCATCAACAACGCGATGAACAGGCCAGGCGGGC
CGGACACGCAGACCGCGCTGCTGTTCGCCGGCCTGTGTGTGCTGACCCTGGCGTGTTCGACCCTGTCCAACCTGTCGACC
AATTACGTCGGCCAGCGAGTCGTCGCCAACCTGCGCCGCGAGCTGGCGGCCAAGGTGCTGGTCGCGCCCATCGAGCAGCT
GGAACGCTATCGCGCGCACCGCCTGATCCCGGTGCTGCTCAACGACGTCAACACCATCAGCACCTTTGCCCTGTCGGTCG
CGCCGATGGTGATCTCGTTTACCGTCACCCTCGGCTGTCTGGCCTATCTGGCCGTGCTGTCCTGGCAGATTCTGGCACTG
ACAGTGCTCACCGTGGTGCTCGGCACCGGCGCACAATACCTGGCGCATGCATTCGGCATGCGCAGCATTCTGGCGGCGCG
CAACAGCGAAGACGAATTGCAGAAGCACTACCAGGCGCTGTCCGCAGGCGCCAAGGAGCTGCGCATTCAGCGCAAACGTC
GTCAGCACATGCTCGACGAAAAGATTCACGGGGCCACTGAACACATCTGCCGCTCGAACATTCGCGCTGCCAACATCTTC
GTCAGCGCGGAAACCTTCGGCTCGATGCTGTTCTTTGCGGTGATCGGCATGGCCATCGCCTTCCAGGCCATGTGGCCGAC
CACCGAGAAAACCGTGCTGGGCGGCTTCGTGCTGGTGATGCTGTACATGAAAGGCCCGCTGGAACGCCTGATGACTGCCC
TGCCCGGCATCAGCCGCGCGCAGATCGCCATGCGCCGCATCGCCGAGCTGTCGTGGAAATTCTCCAGCCCCGAACCGCAC
CTGCTGGTCAGTGACCGCCCGACGTCGCTGGCCAGCATGCACACGCTGGAACTGCACAACCTGCGCTATGACTACCCGCC
GGTCGAGGGCAGCGACGCCTTTCACCTCGGCCCGGTCGACCTGAGCATCAAACAGGGCGACATCGTGTTCATCGTCGGCG
AGAACGGCTGTGGCAAGACTACGCTGATCAAGCTGCTGCTGGGCCTGTACACCCCGCAACAGGGTGAGATCCGCCTGAAT
GGCCAGGCCGTTACCGCGGAAAACCTGGATGACTACCGCCAGCTGTTCACCACGATTTTCGCCGACTACTACCTGTTCGA
CGAGCCGTTGCAGGGCCAGGCCGCGCTGCCGCAGGACGCGGGCAAGTACCTGGAGCGCCTGGACATCGCGCACAAGGTCA
GCATCGAGAACGGTGTCTTCACCACCACCGATCTGTCGACCGGTCAGCGCAAGCGTCTGGCACTGATCAATGCGTGGCTG
GACGAGCGTCAGGTGCTGGTCTTCGACGAGTGGGCCGCCGATCAGGACCCGGCGTTCCGTCGCGTGTTCTACGCCGAGCT
GCTGCCGGAATTGAAGCAACAGGGCAAGACCATCATCGTGATCTCCCATGACGACCGCTATTTCTACGTTGCCGATCAGT
TGGTGCGGATGCAGACCGGGCAGATTCAGGTCGAACAGGTTCGCAACGAAACCCGCGATAAAACCATTACGGCGTGA

Upstream 100 bases:

>100_bases
CTGGCTGGGTTTCCGGGTCGCCCGCGACCTCTGACGGACTTTATGCACTCCCGGCCTGAACCAGCCCAAGCCGCACTCAC
GGACACTGACGAGACACACC

Downstream 100 bases:

>100_bases
TTCACTCGCACCTGAAACGCCCTGCCCGGCCCGTCCGCGAGCGGGGCTTTTTTTGCCTGGCCGCTCCGCGCCACCCTCAA
TTGCTAGCCAAGCGCCATCT

Product: cyclic peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MTRTTESLARETLRILKPFWWLVALSTLLGIVSGLSVTGLLATINNAMNRPGGPDTQTALLFAGLCVLTLACSTLSNLST
NYVGQRVVANLRRELAAKVLVAPIEQLERYRAHRLIPVLLNDVNTISTFALSVAPMVISFTVTLGCLAYLAVLSWQILAL
TVLTVVLGTGAQYLAHAFGMRSILAARNSEDELQKHYQALSAGAKELRIQRKRRQHMLDEKIHGATEHICRSNIRAANIF
VSAETFGSMLFFAVIGMAIAFQAMWPTTEKTVLGGFVLVMLYMKGPLERLMTALPGISRAQIAMRRIAELSWKFSSPEPH
LLVSDRPTSLASMHTLELHNLRYDYPPVEGSDAFHLGPVDLSIKQGDIVFIVGENGCGKTTLIKLLLGLYTPQQGEIRLN
GQAVTAENLDDYRQLFTTIFADYYLFDEPLQGQAALPQDAGKYLERLDIAHKVSIENGVFTTTDLSTGQRKRLALINAWL
DERQVLVFDEWAADQDPAFRRVFYAELLPELKQQGKTIIVISHDDRYFYVADQLVRMQTGQIQVEQVRNETRDKTITA

Sequences:

>Translated_558_residues
MTRTTESLARETLRILKPFWWLVALSTLLGIVSGLSVTGLLATINNAMNRPGGPDTQTALLFAGLCVLTLACSTLSNLST
NYVGQRVVANLRRELAAKVLVAPIEQLERYRAHRLIPVLLNDVNTISTFALSVAPMVISFTVTLGCLAYLAVLSWQILAL
TVLTVVLGTGAQYLAHAFGMRSILAARNSEDELQKHYQALSAGAKELRIQRKRRQHMLDEKIHGATEHICRSNIRAANIF
VSAETFGSMLFFAVIGMAIAFQAMWPTTEKTVLGGFVLVMLYMKGPLERLMTALPGISRAQIAMRRIAELSWKFSSPEPH
LLVSDRPTSLASMHTLELHNLRYDYPPVEGSDAFHLGPVDLSIKQGDIVFIVGENGCGKTTLIKLLLGLYTPQQGEIRLN
GQAVTAENLDDYRQLFTTIFADYYLFDEPLQGQAALPQDAGKYLERLDIAHKVSIENGVFTTTDLSTGQRKRLALINAWL
DERQVLVFDEWAADQDPAFRRVFYAELLPELKQQGKTIIVISHDDRYFYVADQLVRMQTGQIQVEQVRNETRDKTITA
>Mature_557_residues
TRTTESLARETLRILKPFWWLVALSTLLGIVSGLSVTGLLATINNAMNRPGGPDTQTALLFAGLCVLTLACSTLSNLSTN
YVGQRVVANLRRELAAKVLVAPIEQLERYRAHRLIPVLLNDVNTISTFALSVAPMVISFTVTLGCLAYLAVLSWQILALT
VLTVVLGTGAQYLAHAFGMRSILAARNSEDELQKHYQALSAGAKELRIQRKRRQHMLDEKIHGATEHICRSNIRAANIFV
SAETFGSMLFFAVIGMAIAFQAMWPTTEKTVLGGFVLVMLYMKGPLERLMTALPGISRAQIAMRRIAELSWKFSSPEPHL
LVSDRPTSLASMHTLELHNLRYDYPPVEGSDAFHLGPVDLSIKQGDIVFIVGENGCGKTTLIKLLLGLYTPQQGEIRLNG
QAVTAENLDDYRQLFTTIFADYYLFDEPLQGQAALPQDAGKYLERLDIAHKVSIENGVFTTTDLSTGQRKRLALINAWLD
ERQVLVFDEWAADQDPAFRRVFYAELLPELKQQGKTIIVISHDDRYFYVADQLVRMQTGQIQVEQVRNETRDKTITA

Specific function: ATP-driven efflux pump necessary for the secretion of syringomycin. May specifically bind syringomycin and translocate it to the periplasmic space. SyrD is also required for full expression of the syrB gene [H]

COG id: COG4615

COG function: function code QP; ABC-type siderophore export system, fused ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=496, Percent_Identity=22.9838709677419, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI255708477, Length=580, Percent_Identity=23.1034482758621, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI148612844, Length=580, Percent_Identity=23.1034482758621, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI9961252, Length=231, Percent_Identity=27.7056277056277, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4505771, Length=231, Percent_Identity=27.7056277056277, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI9961250, Length=234, Percent_Identity=25.6410256410256, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI171184400, Length=222, Percent_Identity=27.9279279279279, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI42741659, Length=219, Percent_Identity=25.1141552511416, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI150417984, Length=238, Percent_Identity=26.890756302521, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI42490749, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788540, Length=541, Percent_Identity=34.1959334565619, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI1787143, Length=526, Percent_Identity=22.8136882129278, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786654, Length=506, Percent_Identity=23.9130434782609, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787112, Length=565, Percent_Identity=24.9557522123894, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787029, Length=207, Percent_Identity=28.0193236714976, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081709, Length=198, Percent_Identity=29.2929292929293, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787105, Length=232, Percent_Identity=28.8793103448276, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786253, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081791, Length=218, Percent_Identity=28.8990825688073, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789032, Length=195, Percent_Identity=29.2307692307692, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI48994943, Length=212, Percent_Identity=28.3018867924528, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786698, Length=225, Percent_Identity=24, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789891, Length=212, Percent_Identity=27.8301886792453, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786563, Length=215, Percent_Identity=30.2325581395349, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787758, Length=201, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786653, Length=477, Percent_Identity=22.8511530398323, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787370, Length=197, Percent_Identity=27.9187817258883, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=230, Percent_Identity=26.5217391304348, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788761, Length=207, Percent_Identity=29.951690821256, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=198, Percent_Identity=26.7676767676768, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787547, Length=200, Percent_Identity=25.5, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=591, Percent_Identity=24.7038917089679, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193209708, Length=578, Percent_Identity=21.6262975778547, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71984940, Length=520, Percent_Identity=21.5384615384615, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=210, Percent_Identity=27.6190476190476, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17569145, Length=500, Percent_Identity=22, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193202349, Length=449, Percent_Identity=22.4944320712695, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71996809, Length=284, Percent_Identity=25.3521126760563, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=376, Percent_Identity=21.5425531914894, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=267, Percent_Identity=24.3445692883895, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=220, Percent_Identity=26.3636363636364, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558664, Length=219, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=219, Percent_Identity=24.6575342465753, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=220, Percent_Identity=26.8181818181818, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17567269, Length=222, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534520, Length=340, Percent_Identity=22.0588235294118, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=262, Percent_Identity=25.1908396946565, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=438, Percent_Identity=22.3744292237443, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=226, Percent_Identity=24.3362831858407, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=224, Percent_Identity=23.6607142857143, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71996550, Length=222, Percent_Identity=26.1261261261261, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=472, Percent_Identity=24.5762711864407, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323959, Length=294, Percent_Identity=21.4285714285714, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322640, Length=221, Percent_Identity=24.8868778280543, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363262, Length=256, Percent_Identity=25.78125, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653245, Length=256, Percent_Identity=25.78125, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24659289, Length=231, Percent_Identity=28.1385281385281, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643674, Length=202, Percent_Identity=24.7524752475248, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85726357, Length=510, Percent_Identity=22.156862745098, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR005898 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 62181; Mature: 62050

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTTESLARETLRILKPFWWLVALSTLLGIVSGLSVTGLLATINNAMNRPGGPDTQTAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LFAGLCVLTLACSTLSNLSTNYVGQRVVANLRRELAAKVLVAPIEQLERYRAHRLIPVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDVNTISTFALSVAPMVISFTVTLGCLAYLAVLSWQILALTVLTVVLGTGAQYLAHAFGM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RSILAARNSEDELQKHYQALSAGAKELRIQRKRRQHMLDEKIHGATEHICRSNIRAANIF
HHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VSAETFGSMLFFAVIGMAIAFQAMWPTTEKTVLGGFVLVMLYMKGPLERLMTALPGISRA
EEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHH
QIAMRRIAELSWKFSSPEPHLLVSDRPTSLASMHTLELHNLRYDYPPVEGSDAFHLGPVD
HHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCEE
LSIKQGDIVFIVGENGCGKTTLIKLLLGLYTPQQGEIRLNGQAVTAENLDDYRQLFTTIF
EEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCEEEECCCHHHHHHHHHHHH
ADYYLFDEPLQGQAALPQDAGKYLERLDIAHKVSIENGVFTTTDLSTGQRKRLALINAWL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCHHHHHHHHHHH
DERQVLVFDEWAADQDPAFRRVFYAELLPELKQQGKTIIVISHDDRYFYVADQLVRMQTG
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHCC
QIQVEQVRNETRDKTITA
CCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRTTESLARETLRILKPFWWLVALSTLLGIVSGLSVTGLLATINNAMNRPGGPDTQTAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LFAGLCVLTLACSTLSNLSTNYVGQRVVANLRRELAAKVLVAPIEQLERYRAHRLIPVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDVNTISTFALSVAPMVISFTVTLGCLAYLAVLSWQILALTVLTVVLGTGAQYLAHAFGM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RSILAARNSEDELQKHYQALSAGAKELRIQRKRRQHMLDEKIHGATEHICRSNIRAANIF
HHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VSAETFGSMLFFAVIGMAIAFQAMWPTTEKTVLGGFVLVMLYMKGPLERLMTALPGISRA
EEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHH
QIAMRRIAELSWKFSSPEPHLLVSDRPTSLASMHTLELHNLRYDYPPVEGSDAFHLGPVD
HHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCEE
LSIKQGDIVFIVGENGCGKTTLIKLLLGLYTPQQGEIRLNGQAVTAENLDDYRQLFTTIF
EEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCEEEECCCHHHHHHHHHHHH
ADYYLFDEPLQGQAALPQDAGKYLERLDIAHKVSIENGVFTTTDLSTGQRKRLALINAWL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCHHHHHHHHHHH
DERQVLVFDEWAADQDPAFRRVFYAELLPELKQQGKTIIVISHDDRYFYVADQLVRMQTG
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHCC
QIQVEQVRNETRDKTITA
CCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8231810 [H]