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The map label for this gene is pkn1 [H]

Identifier: 66045204

GI number: 66045204

Start: 2275359

End: 2276225

Strand: Reverse

Name: pkn1 [H]

Synonym: Psyr_1964

Alternate gene names: 66045204

Gene position: 2276225-2275359 (Counterclockwise)

Preceding gene: 66045205

Following gene: 66045203

Centisome position: 37.35

GC content: 63.44

Gene sequence:

>867_bases
ATGAAAAAAACATTGCTGCCCCTGTCCGCCCTGCTCGGCCTGTTGCTATGCGGCACCACCCTCGCCGCCACGCCCGCAGC
GGTGCCCGCGCCCGGAAAAGTGTTCAAGGACTGCAAGGACTGCCCGGAAATGGTCGTGCTGCCTGCGGGCACTTTCACCA
TGGGTGCGCCCGAAGAGGAACTGGGTCGTCAGCCGGACGAAGGCCCGCTGCATGACGTGACCTTCGCCAAACCGTTCGCC
ATCAGCCGCTTTCAGGTACTGGCTGGCGAATGGGCCGCCTATATCAAAAGCTCCGGTTACAAAATGCCGGATGGCGATAC
CCGGCCGGGCCGCGAGTGCAAGGCCGGCAAGCCGCGCTACCCGCTGAGCCCGCGTCAGCCTGCGGTGTGCATGGACTGGA
ACGAAGCCAAGGCGTATGTCGAATGGCTGTCGAAAAAAACCGGCAAGTCCTACCACATGGTCAGCGAAGCCCAGCGTGAA
TACGCGGCACGCGGCGGCAGCAAGGGCTCGTTCCCGTTTCCGATGGACGAAGGCAAGCCCTACAGCATTGCCAAACACGC
CAACACCTACGGCCCGGAAGACGGTTTCAGCTACACAGCGCCTGCCGGCAGCTACAGCCCCAACGATTTCGGCATCTACG
ACGCCCACGGCAACGTCTACGAGTGGACCGCCGATTGCGAGACCAGCAACTACAACGGCGCGCCCACCGATGGCAGCGCG
TGGCTGGCCGGTGATTGCACCTGGAAGATGATTCGCGGCAATGACTGGACCGAAGCGCCGATCTTCTCGCGCTCTGGCAA
CCGCAACAGCCGCCAGCCGGATGTACGGGGTGACTGGCTGGGTTTCCGGGTCGCCCGCGACCTCTGA

Upstream 100 bases:

>100_bases
ACAGCGAAGCCGAAATCGATCGTTTCATGACGCTGCTCGCCCGGCGCGCCTGACACAAACTCACCGATTACCTGTTTTCC
GTTTTCCATCGAGACCCGTC

Downstream 100 bases:

>100_bases
CGGACTTTATGCACTCCCGGCCTGAACCAGCCCAAGCCGCACTCACGGACACTGACGAGACACACCATGACCCGCACAAC
TGAAAGCCTCGCCCGGGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKKTLLPLSALLGLLLCGTTLAATPAAVPAPGKVFKDCKDCPEMVVLPAGTFTMGAPEEELGRQPDEGPLHDVTFAKPFA
ISRFQVLAGEWAAYIKSSGYKMPDGDTRPGRECKAGKPRYPLSPRQPAVCMDWNEAKAYVEWLSKKTGKSYHMVSEAQRE
YAARGGSKGSFPFPMDEGKPYSIAKHANTYGPEDGFSYTAPAGSYSPNDFGIYDAHGNVYEWTADCETSNYNGAPTDGSA
WLAGDCTWKMIRGNDWTEAPIFSRSGNRNSRQPDVRGDWLGFRVARDL

Sequences:

>Translated_288_residues
MKKTLLPLSALLGLLLCGTTLAATPAAVPAPGKVFKDCKDCPEMVVLPAGTFTMGAPEEELGRQPDEGPLHDVTFAKPFA
ISRFQVLAGEWAAYIKSSGYKMPDGDTRPGRECKAGKPRYPLSPRQPAVCMDWNEAKAYVEWLSKKTGKSYHMVSEAQRE
YAARGGSKGSFPFPMDEGKPYSIAKHANTYGPEDGFSYTAPAGSYSPNDFGIYDAHGNVYEWTADCETSNYNGAPTDGSA
WLAGDCTWKMIRGNDWTEAPIFSRSGNRNSRQPDVRGDWLGFRVARDL
>Mature_288_residues
MKKTLLPLSALLGLLLCGTTLAATPAAVPAPGKVFKDCKDCPEMVVLPAGTFTMGAPEEELGRQPDEGPLHDVTFAKPFA
ISRFQVLAGEWAAYIKSSGYKMPDGDTRPGRECKAGKPRYPLSPRQPAVCMDWNEAKAYVEWLSKKTGKSYHMVSEAQRE
YAARGGSKGSFPFPMDEGKPYSIAKHANTYGPEDGFSYTAPAGSYSPNDFGIYDAHGNVYEWTADCETSNYNGAPTDGSA
WLAGDCTWKMIRGNDWTEAPIFSRSGNRNSRQPDVRGDWLGFRVARDL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=272, Percent_Identity=28.3088235294118, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI194248087, Length=275, Percent_Identity=29.4545454545455, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI257470977, Length=289, Percent_Identity=27.3356401384083, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI38202250, Length=297, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI194248088, Length=290, Percent_Identity=28.2758620689655, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31487; Mature: 31487

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLLPLSALLGLLLCGTTLAATPAAVPAPGKVFKDCKDCPEMVVLPAGTFTMGAPEEE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCHHH
LGRQPDEGPLHDVTFAKPFAISRFQVLAGEWAAYIKSSGYKMPDGDTRPGRECKAGKPRY
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PLSPRQPAVCMDWNEAKAYVEWLSKKTGKSYHMVSEAQREYAARGGSKGSFPFPMDEGKP
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
YSIAKHANTYGPEDGFSYTAPAGSYSPNDFGIYDAHGNVYEWTADCETSNYNGAPTDGSA
EEEHHCCCCCCCCCCCEECCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCE
WLAGDCTWKMIRGNDWTEAPIFSRSGNRNSRQPDVRGDWLGFRVARDL
EEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MKKTLLPLSALLGLLLCGTTLAATPAAVPAPGKVFKDCKDCPEMVVLPAGTFTMGAPEEE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCHHH
LGRQPDEGPLHDVTFAKPFAISRFQVLAGEWAAYIKSSGYKMPDGDTRPGRECKAGKPRY
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PLSPRQPAVCMDWNEAKAYVEWLSKKTGKSYHMVSEAQREYAARGGSKGSFPFPMDEGKP
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
YSIAKHANTYGPEDGFSYTAPAGSYSPNDFGIYDAHGNVYEWTADCETSNYNGAPTDGSA
EEEHHCCCCCCCCCCCEECCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCE
WLAGDCTWKMIRGNDWTEAPIFSRSGNRNSRQPDVRGDWLGFRVARDL
EEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]