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The map label for this gene is degU [H]

Identifier: 66045180

GI number: 66045180

Start: 2213419

End: 2214087

Strand: Reverse

Name: degU [H]

Synonym: Psyr_1940

Alternate gene names: 66045180

Gene position: 2214087-2213419 (Counterclockwise)

Preceding gene: 66045181

Following gene: 66045179

Centisome position: 36.33

GC content: 64.13

Gene sequence:

>669_bases
ATGACTGACACTGTGCGACTGGTTTTGGCAGACGATCATGAAGTGACGCGTACCGGGTTCGTCTCGCTATTGGCGGGGCA
TCCGGAGTTCGAAGTGGTCGGTCAGGCAGCCGACGGCCAGCAAGCCATCGATCTGTGCCAGGAACTGCAACCGGACATCG
CCATCCTCGACATTCGCATGCCGGTGCTCAACGGACTGGGCGCTGCACGAATTCTCCAGCAGCGCATGCCGGGGCTGAAA
GTGGTGATTTTCACCATGGACGACAGCACCGATCACCTGGAGGCCGCCATGAGCGCCGGTGCGGTGGGCTACCTGCTCAA
GGATGCCAGCCGCGACGAAGTGATCGACGGCCTGCAACGCGTGGCGCGTGGTGAAGAAGCACTGAACAGCGCCGTCAGCG
CGCGCCTGCTGCGGCGCATGACCGAACGCAACACCAGTGGTGCCGCCCTGCCGGAAACCCTAACCCCGCGCGAACGCCAG
GTACTCGGGCTGGTGGCGGGCGGCTTCAGCAACCGGGAAATCGGCGAAAAACTCGGCATCACCACCGGCACGGCCAAGGC
CCACGTGGAAAAGGTCATCGGCAAGCTCGGCGCCTCGGACCGCACTCAGGCGGCGGTACGCGGTGTGGCACTGGGGCTGG
TGAGTCAATCGACGAGCGACTGGCAATGA

Upstream 100 bases:

>100_bases
GCGCCAGCCTGCTCGGCGGGCGCCTGACCTGCGTCAGTCGGCCCGGGCACGGCACCCGACTGCGCGCCATCGTTCCTTTT
ACCGCAGACAAGGCAATGAC

Downstream 100 bases:

>100_bases
CGGCACACGCCAGCAGTCGCTGGGAAGGCCTACCGCTACGCGGCAAGGCACTGGTGGCCATTTCGCTGCCACTGGCGATT
CTGATGTTCTCGCTGGTGCT

Product: LuxR response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTDTVRLVLADDHEVTRTGFVSLLAGHPEFEVVGQAADGQQAIDLCQELQPDIAILDIRMPVLNGLGAARILQQRMPGLK
VVIFTMDDSTDHLEAAMSAGAVGYLLKDASRDEVIDGLQRVARGEEALNSAVSARLLRRMTERNTSGAALPETLTPRERQ
VLGLVAGGFSNREIGEKLGITTGTAKAHVEKVIGKLGASDRTQAAVRGVALGLVSQSTSDWQ

Sequences:

>Translated_222_residues
MTDTVRLVLADDHEVTRTGFVSLLAGHPEFEVVGQAADGQQAIDLCQELQPDIAILDIRMPVLNGLGAARILQQRMPGLK
VVIFTMDDSTDHLEAAMSAGAVGYLLKDASRDEVIDGLQRVARGEEALNSAVSARLLRRMTERNTSGAALPETLTPRERQ
VLGLVAGGFSNREIGEKLGITTGTAKAHVEKVIGKLGASDRTQAAVRGVALGLVSQSTSDWQ
>Mature_221_residues
TDTVRLVLADDHEVTRTGFVSLLAGHPEFEVVGQAADGQQAIDLCQELQPDIAILDIRMPVLNGLGAARILQQRMPGLKV
VIFTMDDSTDHLEAAMSAGAVGYLLKDASRDEVIDGLQRVARGEEALNSAVSARLLRRMTERNTSGAALPETLTPRERQV
LGLVAGGFSNREIGEKLGITTGTAKAHVEKVIGKLGASDRTQAAVRGVALGLVSQSTSDWQ

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=206, Percent_Identity=36.4077669902913, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788521, Length=203, Percent_Identity=33.0049261083744, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=33.0049261083744, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=27.1844660194175, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786747, Length=191, Percent_Identity=25.130890052356, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1788546, Length=201, Percent_Identity=24.8756218905473, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788712, Length=189, Percent_Identity=22.7513227513227, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23651; Mature: 23520

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTVRLVLADDHEVTRTGFVSLLAGHPEFEVVGQAADGQQAIDLCQELQPDIAILDIRM
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEHH
PVLNGLGAARILQQRMPGLKVVIFTMDDSTDHLEAAMSAGAVGYLLKDASRDEVIDGLQR
HHHHCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
VARGEEALNSAVSARLLRRMTERNTSGAALPETLTPRERQVLGLVAGGFSNREIGEKLGI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCC
TTGTAKAHVEKVIGKLGASDRTQAAVRGVALGLVSQSTSDWQ
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDTVRLVLADDHEVTRTGFVSLLAGHPEFEVVGQAADGQQAIDLCQELQPDIAILDIRM
CCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEHH
PVLNGLGAARILQQRMPGLKVVIFTMDDSTDHLEAAMSAGAVGYLLKDASRDEVIDGLQR
HHHHCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
VARGEEALNSAVSARLLRRMTERNTSGAALPETLTPRERQVLGLVAGGFSNREIGEKLGI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCC
TTGTAKAHVEKVIGKLGASDRTQAAVRGVALGLVSQSTSDWQ
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]