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The map label for this gene is umuD [H]

Identifier: 66045157

GI number: 66045157

Start: 2190664

End: 2191107

Strand: Direct

Name: umuD [H]

Synonym: Psyr_1916

Alternate gene names: 66045157

Gene position: 2190664-2191107 (Clockwise)

Preceding gene: 66045156

Following gene: 66045158

Centisome position: 35.95

GC content: 58.78

Gene sequence:

>444_bases
ATGAGTGTTACCTTCCTTGGCCCGTTGTCGGCAGGGGGCATCAAACTCCCGTTCATATCGCTGTCGTCCGTTGGCTCCAG
ATCGCCAGTGGTCGAGAAGCATGTTTCCATCGCCGAGCTTTGTGAGGTCCGTGAGCCACACGCCTACCTGGCCAGGATCG
AAGACCAAGGTATGCAGGGGAGCGGCATGTGCAGCGGGGATATGCTGGTGGTCGACCGCAGCCAGTACGCCGAGCACGGT
GACATCGTCGTTGCCTCGCTCAATGCACGGCAGATCTGCCGACGTTTGCACATGCGCGGCGATGTGGTGATTCTGGAATC
GCAAAACCCGGATTACCCACCACTGCATGTCACCGACAACGATGACCTGATCATCCTGGGCGTGGTGACCTACAGCCTGA
AAAACCTGCTGGAGGGCCGCGCTGCATCATCAGCTCATCGATGA

Upstream 100 bases:

>100_bases
GTCCGCGCCATCTGTCGAGGTATCTGGCATTGCGATTGACCTGAGCGCCGATAAACGATTAACTGTATATGTATACAGTT
AATCAGAAAAGGCTCGCCTC

Downstream 100 bases:

>100_bases
ACAGACGCATGTTCTTGCATTGCACGCCGCTGCATGATCTGCTGCCCACTCTTTGGCTTTTAGCGGAATACCGAGCGCAT
GCAAGAACGACTTGACCAGT

Product: peptidase S24, S26A and S26B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSVTFLGPLSAGGIKLPFISLSSVGSRSPVVEKHVSIAELCEVREPHAYLARIEDQGMQGSGMCSGDMLVVDRSQYAEHG
DIVVASLNARQICRRLHMRGDVVILESQNPDYPPLHVTDNDDLIILGVVTYSLKNLLEGRAASSAHR

Sequences:

>Translated_147_residues
MSVTFLGPLSAGGIKLPFISLSSVGSRSPVVEKHVSIAELCEVREPHAYLARIEDQGMQGSGMCSGDMLVVDRSQYAEHG
DIVVASLNARQICRRLHMRGDVVILESQNPDYPPLHVTDNDDLIILGVVTYSLKNLLEGRAASSAHR
>Mature_146_residues
SVTFLGPLSAGGIKLPFISLSSVGSRSPVVEKHVSIAELCEVREPHAYLARIEDQGMQGSGMCSGDMLVVDRSQYAEHGD
IVVASLNARQICRRLHMRGDVVILESQNPDYPPLHVTDNDDLIILGVVTYSLKNLLEGRAASSAHR

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=123, Percent_Identity=30.0813008130081, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 15954; Mature: 15822

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTFLGPLSAGGIKLPFISLSSVGSRSPVVEKHVSIAELCEVREPHAYLARIEDQGMQG
CCEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHCCHHHHHHCCCCHHHEEEHHCCCCCC
SGMCSGDMLVVDRSQYAEHGDIVVASLNARQICRRLHMRGDVVILESQNPDYPPLHVTDN
CCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCEEEECC
DDLIILGVVTYSLKNLLEGRAASSAHR
CCEEEEHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SVTFLGPLSAGGIKLPFISLSSVGSRSPVVEKHVSIAELCEVREPHAYLARIEDQGMQG
CEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHCCHHHHHHCCCCHHHEEEHHCCCCCC
SGMCSGDMLVVDRSQYAEHGDIVVASLNARQICRRLHMRGDVVILESQNPDYPPLHVTDN
CCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCEEEECC
DDLIILGVVTYSLKNLLEGRAASSAHR
CCEEEEHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609; 1910151 [H]