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The map label for this gene is mtnD [H]

Identifier: 66045100

GI number: 66045100

Start: 2133956

End: 2134501

Strand: Direct

Name: mtnD [H]

Synonym: Psyr_1856

Alternate gene names: 66045100

Gene position: 2133956-2134501 (Clockwise)

Preceding gene: 66045099

Following gene: 66045101

Centisome position: 35.02

GC content: 58.24

Gene sequence:

>546_bases
ATGAGCAGCCTGTCCGTTTATCACGTTTCAAGCCCTGATATGCCCAACAAGGTGCTGACCCATCTGGAAGACATCGCGTC
GACACTGGCCGAGCACGGCGTGGCGTTCGACCGTTGGGAAGCCGCGACGCCGATCACTCCCGGTGCCAGTCAGGAAGAGG
TGATCAGCGCCTATCGCACGCAGATCGACACGCTGATGACCGAACGCGGTTATGTCACCGTGGACGTCATCAGTCTCAAC
AGCGATCACCCGCAAAAAGCCGAATTGCGCGCCAGGTTTCTTGAAGAGCACCGCCACGGCGAAGACGAGGTACGCTTTTT
CGTCGCCGGGCGGGGCTTGTTCACCTTGCACATCGACGACTATGTGTATGCCGTGCTGTGCGAAAAGAACGACCTGATTT
CCGTACCGGCCGGCACGCGGCACTGGTTCGATATGGGCGAGAACCCGCACTTCGTTGCCATCCGCCTGTTCAATAATCCG
GAAGGCTGGGTAGCAAACTTTACCGGTGAAGACATTGCCGGCCGTTTTCCACGGCTGGAAGACTGA

Upstream 100 bases:

>100_bases
GCGCGGTAATGAACCGCTGACAACGTCTTGCCAAACCAGTCTGTAAGCCTGACCGGCCTGTAAAAGCCGGAAGGCGTTGC
ACCAAACCGAGGATTCACGC

Downstream 100 bases:

>100_bases
CAGGAGCCCCATTCTGATGCCCATCAAAGCTATCCTCACGGATATCGAAGGCACCACCAGTGCAGTGAGTTTCGTTTTCG
ACGTGCTGTTTCCGTTCGCC

Product: acireductone dioxygenase, ARD

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSSLSVYHVSSPDMPNKVLTHLEDIASTLAEHGVAFDRWEAATPITPGASQEEVISAYRTQIDTLMTERGYVTVDVISLN
SDHPQKAELRARFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTRHWFDMGENPHFVAIRLFNNP
EGWVANFTGEDIAGRFPRLED

Sequences:

>Translated_181_residues
MSSLSVYHVSSPDMPNKVLTHLEDIASTLAEHGVAFDRWEAATPITPGASQEEVISAYRTQIDTLMTERGYVTVDVISLN
SDHPQKAELRARFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTRHWFDMGENPHFVAIRLFNNP
EGWVANFTGEDIAGRFPRLED
>Mature_180_residues
SSLSVYHVSSPDMPNKVLTHLEDIASTLAEHGVAFDRWEAATPITPGASQEEVISAYRTQIDTLMTERGYVTVDVISLNS
DHPQKAELRARFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTRHWFDMGENPHFVAIRLFNNPE
GWVANFTGEDIAGRFPRLED

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family [H]

Homologues:

Organism=Homo sapiens, GI171460928, Length=107, Percent_Identity=32.7102803738318, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710 [H]

Pfam domain/function: PF03079 ARD [H]

EC number: =1.13.11.54; =1.13.11.53 [H]

Molecular weight: Translated: 20458; Mature: 20327

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLSVYHVSSPDMPNKVLTHLEDIASTLAEHGVAFDRWEAATPITPGASQEEVISAYRT
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QIDTLMTERGYVTVDVISLNSDHPQKAELRARFLEEHRHGEDEVRFFVAGRGLFTLHIDD
HHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
YVYAVLCEKNDLISVPAGTRHWFDMGENPHFVAIRLFNNPEGWVANFTGEDIAGRFPRLE
EEEEEEECCCCEEECCCCCCHHHCCCCCCCEEEEEEEECCCCEEEECCCCCHHCCCCCCC
D
C
>Mature Secondary Structure 
SSLSVYHVSSPDMPNKVLTHLEDIASTLAEHGVAFDRWEAATPITPGASQEEVISAYRT
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QIDTLMTERGYVTVDVISLNSDHPQKAELRARFLEEHRHGEDEVRFFVAGRGLFTLHIDD
HHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
YVYAVLCEKNDLISVPAGTRHWFDMGENPHFVAIRLFNNPEGWVANFTGEDIAGRFPRLE
EEEEEEECCCCEEECCCCCCHHHCCCCCCCEEEEEEEECCCCEEEECCCCCHHCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA