Click here to switch to the map view.

The map label for this gene is mtnC [H]

Identifier: 66045101

GI number: 66045101

Start: 2134518

End: 2135201

Strand: Direct

Name: mtnC [H]

Synonym: Psyr_1857

Alternate gene names: 66045101

Gene position: 2134518-2135201 (Clockwise)

Preceding gene: 66045100

Following gene: 66045102

Centisome position: 35.03

GC content: 60.09

Gene sequence:

>684_bases
ATGCCCATCAAAGCTATCCTCACGGATATCGAAGGCACCACCAGTGCAGTGAGTTTCGTTTTCGACGTGCTGTTTCCGTT
CGCCAGAAAGCACCTGCCCGCATTCGTTCGCGAACATGCCGAGCAACCGGCCGTGGCGCAGCAGTTGCAGGCGGTGCGCG
ACCTGGCCGGTGAGCCGGACGCCGATGTCGAGCGCGTCATTGCACTCCTGCTGGAATGGATCGCCGAGGACCGCAAAGCC
ACACCTCTCAAGGCCCTGCAGGGGATGGTCTGGGAGCAGGGTTACAACGCCGGACAGCTAAAGGGGCATGTTTATCCGGA
TGCTGTCGATGCCTTGAAACACTGGCATCAACAGGGCTACCGGCTTTACGTTTATTCCTCGGGCTCTATTCAGGCTCAGC
AATTGATTTTCGGCTGTTCCGAGGCGGGCGATCTGTCCGGCCTGTTCAGCGGTTACTTCGATACGACCTCCGGCCCCAAG
CGCGAAGCGCAGTCCTACCGGACGATTGCCCAGGCAATGGACTGTCCTGCCGGGGACATTCTGTTCCTGTCGGATATCGT
CGAAGAACTCGATGCCGCACAGGCCGCCGGCATGGCCACCTGCGGTCTTGCGCGTGATGGCGGGGCACTTGCCGGGCACC
GGTATGTGACCAGTTTTGCGCTTATCGACCCAGCCTCTTTCTAG

Upstream 100 bases:

>100_bases
CGCCTGTTCAATAATCCGGAAGGCTGGGTAGCAAACTTTACCGGTGAAGACATTGCCGGCCGTTTTCCACGGCTGGAAGA
CTGACAGGAGCCCCATTCTG

Downstream 100 bases:

>100_bases
AAGACTCCCGCCTGCTGTGCGCGGCATCGTCCTGATGCCGCTGCATTGAAAACTGCCTGCCGCAAGGCTCACGCACTACG
TCTGTAGGGCTTTTCCTGCT

Product: HAD family 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MPIKAILTDIEGTTSAVSFVFDVLFPFARKHLPAFVREHAEQPAVAQQLQAVRDLAGEPDADVERVIALLLEWIAEDRKA
TPLKALQGMVWEQGYNAGQLKGHVYPDAVDALKHWHQQGYRLYVYSSGSIQAQQLIFGCSEAGDLSGLFSGYFDTTSGPK
REAQSYRTIAQAMDCPAGDILFLSDIVEELDAAQAAGMATCGLARDGGALAGHRYVTSFALIDPASF

Sequences:

>Translated_227_residues
MPIKAILTDIEGTTSAVSFVFDVLFPFARKHLPAFVREHAEQPAVAQQLQAVRDLAGEPDADVERVIALLLEWIAEDRKA
TPLKALQGMVWEQGYNAGQLKGHVYPDAVDALKHWHQQGYRLYVYSSGSIQAQQLIFGCSEAGDLSGLFSGYFDTTSGPK
REAQSYRTIAQAMDCPAGDILFLSDIVEELDAAQAAGMATCGLARDGGALAGHRYVTSFALIDPASF
>Mature_226_residues
PIKAILTDIEGTTSAVSFVFDVLFPFARKHLPAFVREHAEQPAVAQQLQAVRDLAGEPDADVERVIALLLEWIAEDRKAT
PLKALQGMVWEQGYNAGQLKGHVYPDAVDALKHWHQQGYRLYVYSSGSIQAQQLIFGCSEAGDLSGLFSGYFDTTSGPKR
EAQSYRTIAQAMDCPAGDILFLSDIVEELDAAQAAGMATCGLARDGGALAGHRYVTSFALIDPASF

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family [H]

Homologues:

Organism=Homo sapiens, GI10864017, Length=240, Percent_Identity=35.8333333333333, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI115533232, Length=234, Percent_Identity=38.4615384615385, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6320797, Length=220, Percent_Identity=39.0909090909091, Blast_Score=138, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281360080, Length=230, Percent_Identity=43.9130434782609, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24644163, Length=230, Percent_Identity=43.9130434782609, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.77 [H]

Molecular weight: Translated: 24609; Mature: 24478

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKAILTDIEGTTSAVSFVFDVLFPFARKHLPAFVREHAEQPAVAQQLQAVRDLAGEPD
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
ADVERVIALLLEWIAEDRKATPLKALQGMVWEQGYNAGQLKGHVYPDAVDALKHWHQQGY
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
RLYVYSSGSIQAQQLIFGCSEAGDLSGLFSGYFDTTSGPKREAQSYRTIAQAMDCPAGDI
EEEEEECCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCH
LFLSDIVEELDAAQAAGMATCGLARDGGALAGHRYVTSFALIDPASF
HHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PIKAILTDIEGTTSAVSFVFDVLFPFARKHLPAFVREHAEQPAVAQQLQAVRDLAGEPD
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
ADVERVIALLLEWIAEDRKATPLKALQGMVWEQGYNAGQLKGHVYPDAVDALKHWHQQGY
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
RLYVYSSGSIQAQQLIFGCSEAGDLSGLFSGYFDTTSGPKREAQSYRTIAQAMDCPAGDI
EEEEEECCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCH
LFLSDIVEELDAAQAAGMATCGLARDGGALAGHRYVTSFALIDPASF
HHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA