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The map label for this gene is mtnB [H]

Identifier: 66045099

GI number: 66045099

Start: 2133261

End: 2133875

Strand: Direct

Name: mtnB [H]

Synonym: Psyr_1855

Alternate gene names: 66045099

Gene position: 2133261-2133875 (Clockwise)

Preceding gene: 66045098

Following gene: 66045100

Centisome position: 35.01

GC content: 59.67

Gene sequence:

>615_bases
ATGAGCCGCGAACAATTGAGCCTGGAAATCATTGAGGCCGGGCGTTTTCTGTACGGCCGTGGCTGGTCGCCTGCCACCAG
CAGCAATTATTCTGCGCGCCTTTCTGCCAGTGAGGCGTTGTTGACCGTATCCGGCAAGCACAAGGGCCAGTTGGGCCCTG
ACGATGTGCTGGCCACCGATCTGGCTGGCAACAGCCTGGAGCCCGGTAAAAAGCCGTCTGCCGAAACCTTGCTGCATACC
CAGTTGTACAGCTGCAGGCCGCAAGTCGGCGCGGTGCTGCACACCCATTCGGTGAACGCGACCGTGTTGTCGAGGCTGAC
CACGGCCGATCATCTGGTGTTCGAGGATTACGAACTGCAGAAGGCCTTTAGCGGCGTGGTCACTCACGAGTCGCAGGTCG
TGGTACCGATTTTCGACAACGATCAGGACATTGCCCGTCTCGCGGCAAAGGTGCAGCCTTGGCTGGACACCCATCCCGAG
TGCGCCGGCTACCTGATCCGCGGTCATGGCCTCTACACCTGGGGGGCTAAAATGAGCGACGCCTTGCGCCAGATCGAAGC
GTTCGAGTTCCTGTTCGAATGCGAACTGAAAATGCGCGCGGTAATGAACCGCTGA

Upstream 100 bases:

>100_bases
GCTGGAACGCGCTGGGGCCGACCTGGACCTTTGCCATCGCCAGCCTTGCAGCCTTTGCCGCTGCCGTCATGATTGTCACA
CCCAAGAAAGAGGAAGGTGT

Downstream 100 bases:

>100_bases
CAACGTCTTGCCAAACCAGTCTGTAAGCCTGACCGGCCTGTAAAAGCCGGAAGGCGTTGCACCAAACCGAGGATTCACGC
ATGAGCAGCCTGTCCGTTTA

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSREQLSLEIIEAGRFLYGRGWSPATSSNYSARLSASEALLTVSGKHKGQLGPDDVLATDLAGNSLEPGKKPSAETLLHT
QLYSCRPQVGAVLHTHSVNATVLSRLTTADHLVFEDYELQKAFSGVVTHESQVVVPIFDNDQDIARLAAKVQPWLDTHPE
CAGYLIRGHGLYTWGAKMSDALRQIEAFEFLFECELKMRAVMNR

Sequences:

>Translated_204_residues
MSREQLSLEIIEAGRFLYGRGWSPATSSNYSARLSASEALLTVSGKHKGQLGPDDVLATDLAGNSLEPGKKPSAETLLHT
QLYSCRPQVGAVLHTHSVNATVLSRLTTADHLVFEDYELQKAFSGVVTHESQVVVPIFDNDQDIARLAAKVQPWLDTHPE
CAGYLIRGHGLYTWGAKMSDALRQIEAFEFLFECELKMRAVMNR
>Mature_203_residues
SREQLSLEIIEAGRFLYGRGWSPATSSNYSARLSASEALLTVSGKHKGQLGPDDVLATDLAGNSLEPGKKPSAETLLHTQ
LYSCRPQVGAVLHTHSVNATVLSRLTTADHLVFEDYELQKAFSGVVTHESQVVVPIFDNDQDIARLAAKVQPWLDTHPEC
AGYLIRGHGLYTWGAKMSDALRQIEAFEFLFECELKMRAVMNR

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily [H]

Homologues:

Organism=Homo sapiens, GI166235186, Length=209, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18859685, Length=195, Percent_Identity=28.7179487179487, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR017714 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.2.1.109 [H]

Molecular weight: Translated: 22530; Mature: 22399

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSREQLSLEIIEAGRFLYGRGWSPATSSNYSARLSASEALLTVSGKHKGQLGPDDVLATD
CCCHHHHHEEEECCCEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHEEEC
LAGNSLEPGKKPSAETLLHTQLYSCRPQVGAVLHTHSVNATVLSRLTTADHLVFEDYELQ
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHEEECCHHHH
KAFSGVVTHESQVVVPIFDNDQDIARLAAKVQPWLDTHPECAGYLIRGHGLYTWGAKMSD
HHHHHHEECCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEECCHHHH
ALRQIEAFEFLFECELKMRAVMNR
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SREQLSLEIIEAGRFLYGRGWSPATSSNYSARLSASEALLTVSGKHKGQLGPDDVLATD
CCHHHHHEEEECCCEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHEEEC
LAGNSLEPGKKPSAETLLHTQLYSCRPQVGAVLHTHSVNATVLSRLTTADHLVFEDYELQ
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHEEECCHHHH
KAFSGVVTHESQVVVPIFDNDQDIARLAAKVQPWLDTHPECAGYLIRGHGLYTWGAKMSD
HHHHHHEECCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEECCHHHH
ALRQIEAFEFLFECELKMRAVMNR
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA