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The map label for this gene is hcaT [H]

Identifier: 66045098

GI number: 66045098

Start: 2132101

End: 2133264

Strand: Direct

Name: hcaT [H]

Synonym: Psyr_1854

Alternate gene names: 66045098

Gene position: 2132101-2133264 (Clockwise)

Preceding gene: 66045097

Following gene: 66045099

Centisome position: 34.99

GC content: 61.68

Gene sequence:

>1164_bases
GTGGCGCAACCTGGCGGCGGACAGCTGCCTTACTGGCGGCTGTCCGGGTTCTACGTATGCTATTTCGCCTTGCTGGGCCT
GTCGGCGCCGTTCATGGCCCTTTACCTGCATCATCTGGGTTTTTCCAGCGCACGGATCGGCGAGCTGGTCGCCATTCCCA
TGCTGATGCGCTGCGTCGCGCCCAATCTCTGGGGGTGGCTGGGTGATCACACCGGTTGGCGTCTGACCATTGTGCGGTCT
GGCGCCATCTGCACGTTGCTGGCGTTTTCGCTGATTCTGGTCGAAAAAAGCTATGCCTGGCTGGCGATGGTCATGGCGCT
CTATGCGTTCTTCTGGCACGCCATCCTGCCGCAGTTCGAAGTCATCACCCTCGCGCACCTGCAAGGCCAGGCCTCGCGTT
ACAGCCAGGTTCGGCTGTGGGGTTCGATCGGTTTCATTCTGGCCGTCGTGGTGCTGGGGCGGGTGTTTGAATGGTTCAGC
CTGGACCTGTTCCCCTACATCGCGCTGACGATCATGTCCGGTATCGTTATCAGCAGCTGGTGGGTGCCGAATGCGCAACC
CTCACCGTCGAGCCGCGAAACCGGGTCGGGCGGCTTTCTCAGGCAACTGGCGCGCCCCGGTGTATGGGCGTTCTACCTCA
GTGTTGCGCTGATGGTGCTCAGCCATGGGCCGTATTACACCTTTTTGACCCTGCACCTCGAAGCGCTCGGTTACAGCCGC
GGCCTGATCGGCCTGCTATGGGCGGTCGGCGTGGTGGCTGAAGTGCTGATGTTCATGGTCATGAGCCGGATTCTGCAGCG
CTTCACCGTGCGCCAGGTACTGTTCGCCAGTTTTCTGCTGGCCGCACTGCGCTGGCTGCTGCTGGGGCTGTTTGCCGATC
ACCTCACCGCGCTGCTGATTGCCCAGGTGATGCACGCCGCCACGTTCGGCAGCTTTCACGCCGCTGCCATTCATTTCGTG
CAAAGTAGCTTCGGTCCGCGTCAGCAAGGTCAGGGGCAAGCGCTTTATGCTGCCTTGTCCGGGGTCGGCGGGGCGTTGGG
CGCTCTGTATTCCGGTTACAGCTGGAACGCGCTGGGGCCGACCTGGACCTTTGCCATCGCCAGCCTTGCAGCCTTTGCCG
CTGCCGTCATGATTGTCACACCCAAGAAAGAGGAAGGTGTATGA

Upstream 100 bases:

>100_bases
TCACCTGCTGCGCCATCGCGGTCAGAACGCCGACGTCAGCGTCAACACACCTGTGCTGGGGCAGGTGTAATGCACGCCGT
CACGGTTGCGGATTGCTAGC

Downstream 100 bases:

>100_bases
GCCGCGAACAATTGAGCCTGGAAATCATTGAGGCCGGGCGTTTTCTGTACGGCCGTGGCTGGTCGCCTGCCACCAGCAGC
AATTATTCTGCGCGCCTTTC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAQPGGGQLPYWRLSGFYVCYFALLGLSAPFMALYLHHLGFSSARIGELVAIPMLMRCVAPNLWGWLGDHTGWRLTIVRS
GAICTLLAFSLILVEKSYAWLAMVMALYAFFWHAILPQFEVITLAHLQGQASRYSQVRLWGSIGFILAVVVLGRVFEWFS
LDLFPYIALTIMSGIVISSWWVPNAQPSPSSRETGSGGFLRQLARPGVWAFYLSVALMVLSHGPYYTFLTLHLEALGYSR
GLIGLLWAVGVVAEVLMFMVMSRILQRFTVRQVLFASFLLAALRWLLLGLFADHLTALLIAQVMHAATFGSFHAAAIHFV
QSSFGPRQQGQGQALYAALSGVGGALGALYSGYSWNALGPTWTFAIASLAAFAAAVMIVTPKKEEGV

Sequences:

>Translated_387_residues
MAQPGGGQLPYWRLSGFYVCYFALLGLSAPFMALYLHHLGFSSARIGELVAIPMLMRCVAPNLWGWLGDHTGWRLTIVRS
GAICTLLAFSLILVEKSYAWLAMVMALYAFFWHAILPQFEVITLAHLQGQASRYSQVRLWGSIGFILAVVVLGRVFEWFS
LDLFPYIALTIMSGIVISSWWVPNAQPSPSSRETGSGGFLRQLARPGVWAFYLSVALMVLSHGPYYTFLTLHLEALGYSR
GLIGLLWAVGVVAEVLMFMVMSRILQRFTVRQVLFASFLLAALRWLLLGLFADHLTALLIAQVMHAATFGSFHAAAIHFV
QSSFGPRQQGQGQALYAALSGVGGALGALYSGYSWNALGPTWTFAIASLAAFAAAVMIVTPKKEEGV
>Mature_386_residues
AQPGGGQLPYWRLSGFYVCYFALLGLSAPFMALYLHHLGFSSARIGELVAIPMLMRCVAPNLWGWLGDHTGWRLTIVRSG
AICTLLAFSLILVEKSYAWLAMVMALYAFFWHAILPQFEVITLAHLQGQASRYSQVRLWGSIGFILAVVVLGRVFEWFSL
DLFPYIALTIMSGIVISSWWVPNAQPSPSSRETGSGGFLRQLARPGVWAFYLSVALMVLSHGPYYTFLTLHLEALGYSRG
LIGLLWAVGVVAEVLMFMVMSRILQRFTVRQVLFASFLLAALRWLLLGLFADHLTALLIAQVMHAATFGSFHAAAIHFVQ
SSFGPRQQGQGQALYAALSGVGGALGALYSGYSWNALGPTWTFAIASLAAFAAAVMIVTPKKEEGV

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=381, Percent_Identity=27.5590551181102, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 42428; Mature: 42296

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPGGGQLPYWRLSGFYVCYFALLGLSAPFMALYLHHLGFSSARIGELVAIPMLMRCVA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
PNLWGWLGDHTGWRLTIVRSGAICTLLAFSLILVEKSYAWLAMVMALYAFFWHAILPQFE
CHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VITLAHLQGQASRYSQVRLWGSIGFILAVVVLGRVFEWFSLDLFPYIALTIMSGIVISSW
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WVPNAQPSPSSRETGSGGFLRQLARPGVWAFYLSVALMVLSHGPYYTFLTLHLEALGYSR
CCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
GLIGLLWAVGVVAEVLMFMVMSRILQRFTVRQVLFASFLLAALRWLLLGLFADHLTALLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQVMHAATFGSFHAAAIHFVQSSFGPRQQGQGQALYAALSGVGGALGALYSGYSWNALGP
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCH
TWTFAIASLAAFAAAVMIVTPKKEEGV
HHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure 
AQPGGGQLPYWRLSGFYVCYFALLGLSAPFMALYLHHLGFSSARIGELVAIPMLMRCVA
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
PNLWGWLGDHTGWRLTIVRSGAICTLLAFSLILVEKSYAWLAMVMALYAFFWHAILPQFE
CHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VITLAHLQGQASRYSQVRLWGSIGFILAVVVLGRVFEWFSLDLFPYIALTIMSGIVISSW
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WVPNAQPSPSSRETGSGGFLRQLARPGVWAFYLSVALMVLSHGPYYTFLTLHLEALGYSR
CCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
GLIGLLWAVGVVAEVLMFMVMSRILQRFTVRQVLFASFLLAALRWLLLGLFADHLTALLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQVMHAATFGSFHAAAIHFVQSSFGPRQQGQGQALYAALSGVGGALGALYSGYSWNALGP
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCH
TWTFAIASLAAFAAAVMIVTPKKEEGV
HHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]