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The map label for this gene is acoR [H]

Identifier: 66044981

GI number: 66044981

Start: 1971971

End: 1973824

Strand: Reverse

Name: acoR [H]

Synonym: Psyr_1736

Alternate gene names: 66044981

Gene position: 1973824-1971971 (Counterclockwise)

Preceding gene: 66044988

Following gene: 66044978

Centisome position: 32.39

GC content: 59.98

Gene sequence:

>1854_bases
ATGTCTCAAACCAGCGCTTCGCTTGCTCACGACATCATCATTCAGGATTCATGGACCCGCTGCCGGGACTTCGGCCTCAG
TCATCAGACGCGTCCCTCATTCGGCCAATTGCCGGGGACGGAGGTTTCCAGGCTGCTGGAGCGCCATCACGGACTGGTAC
AGACCACCCATCAGGAGGTCCTGCCGGTCTACGAAAACATTCTCAGCAACTCCAGCTGTCTGATTCTGCTGGCCGACCGT
CAAGGTCAGTTGCTCAAGTCATGGGGTGCACAACGCTTCGTCGAATCGTCCCAGGCTCAAGGCTTCATGCCAGGTGCCAG
CTGGAACGAACGCGGCACGGGCACCAACGCCATCGGCACGGCGCTGGCCTGCGAAGAGGCCATCCATATTGAACCGGACG
AGCATTTCCTCAAGGCCAACCGTTTCATGACCGGTTCGGCCTCACCGATCTTCGACGCAGACAGGCGCATCATCGCCGTG
CTGGATGTGTCCAGCGACAGCTTCCTGCCACCCTCGCACACGCTGGGCATGGTCAAAATGATGAGCCAGTCGGTGGAAAA
CCGCCTGATCCTCGACCAGTTTCGCGACTCCCATTTCCAGCTGATCTTCAATACCGGCCTGAACAACCTCGACAGCCAAT
GGGCTGGCCTGCTGATTTTTGACGAAAGTGGCCAGATCCTGTGCGCCAATCGGCGCGCCGACACCTTGCTGGGGACGGCT
CCGGCCGGTGCCAGCATCGAGACGCTGTTCAAATGTCCGATCCTGCAATTGCTCAGCGAAACCGAAGCGCGTCCGTTTGC
GCTGCATGCATTTGGCAACAATCGCTTTCAATGCCTGCTCAAGCGTCCGACTCGCAAACCATTGAAGCTGCATTGCGTCC
AGGCTGCGCAGGTGCCTGCTGCACCACGAAACCTTGATCTGCAGGCGATCAGCTTGGGCGATGCGAAGGTCGAGAAGGCT
GTGCGTCAGGCGCAGCGGCTGCTGGAAAAAGACATCCCACTGCTCATTCATGGTGAAACCGGGGTTGGCAAGGAAGTCTT
TGTCAAAGCCCTGCATCAGGCCAGTGCGCGCGCCAGCCAGCCGCTGATCGCGGTCAACTGTGCAGCGATCCCGGCCGATC
TGGTCGAGGCCGAGCTGTTTGGCTATGAAAGAGGCGCCTTCACCGGGGCCAACCAGAAAGGCAGCATCGGCCTGATCCGC
AAGGCCGACAAAGGCACGCTGTTTCTGGATGAGGTGGGCGACATGCCGATGCCGGTACAGGCGCGATTGCTGCGTGTGCT
GCAAGAGCGCTGCGTTCAGCCATTGGGCAGCAGCGAGCTGTATCCGGTCGATATACGGCTGATTTCAGCCACCAACCGGG
GTCTGCGCGATCAGGTCCAGGCGGGGCTTTTTCGCCAGGATCTTTATTATCGGATCAGCGGCCTGAGCATCGAACTCCCG
CCCCTCCGCGAGCGGACTGACAAACATGCGCTGATCCAGCGAATCTGGGAGCGGCACCGTGATGCTCACCAGCGCGCGGG
CTTTTCCAGAGAAGTGCTTGAATTATTCGAGCATCACCCCTGGCCGGGCAACCTGCGCCAGCTCAACAGCGTGATTCAGG
TAGCGCTGGCACTGGCCGACGAACAGCCGATCGGCACCGACCATCTGCCCGAGGACTTTCTGCTCGACGCTCACGCGGAT
GAGGAATGCCGTGTCCCGCTCAGGACTCAGGAGTCGGCCACTCGCTTTCACTCGAGCGAAGACCTCGGCCAACTGTTTCA
AGCGGCAGGCGGGAATGTTTCACAGTTGGCCAAACGTCTGGGCGTCAGCCGCAACACACTGTACAAGCGGTTGCGGGAAC
AGCGGATCGTTTAG

Upstream 100 bases:

>100_bases
GAACACAACTGAACGACACTGGACTGACGTTGCGGGCAAGGATGGTCACGCCGACGGGACCTAAAAACAAAAACAATACG
TCACATTCGCAGGCATCCTC

Downstream 100 bases:

>100_bases
TGTTTGACGCTCGGCAGGCTGCACATCGAGGACAGGACGCGGAGCGTCCAGAACAGCATGCCCATGCGGAGCACGGGCAC
GATAGTATTTCAGGGATAGT

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MSQTSASLAHDIIIQDSWTRCRDFGLSHQTRPSFGQLPGTEVSRLLERHHGLVQTTHQEVLPVYENILSNSSCLILLADR
QGQLLKSWGAQRFVESSQAQGFMPGASWNERGTGTNAIGTALACEEAIHIEPDEHFLKANRFMTGSASPIFDADRRIIAV
LDVSSDSFLPPSHTLGMVKMMSQSVENRLILDQFRDSHFQLIFNTGLNNLDSQWAGLLIFDESGQILCANRRADTLLGTA
PAGASIETLFKCPILQLLSETEARPFALHAFGNNRFQCLLKRPTRKPLKLHCVQAAQVPAAPRNLDLQAISLGDAKVEKA
VRQAQRLLEKDIPLLIHGETGVGKEVFVKALHQASARASQPLIAVNCAAIPADLVEAELFGYERGAFTGANQKGSIGLIR
KADKGTLFLDEVGDMPMPVQARLLRVLQERCVQPLGSSELYPVDIRLISATNRGLRDQVQAGLFRQDLYYRISGLSIELP
PLRERTDKHALIQRIWERHRDAHQRAGFSREVLELFEHHPWPGNLRQLNSVIQVALALADEQPIGTDHLPEDFLLDAHAD
EECRVPLRTQESATRFHSSEDLGQLFQAAGGNVSQLAKRLGVSRNTLYKRLREQRIV

Sequences:

>Translated_617_residues
MSQTSASLAHDIIIQDSWTRCRDFGLSHQTRPSFGQLPGTEVSRLLERHHGLVQTTHQEVLPVYENILSNSSCLILLADR
QGQLLKSWGAQRFVESSQAQGFMPGASWNERGTGTNAIGTALACEEAIHIEPDEHFLKANRFMTGSASPIFDADRRIIAV
LDVSSDSFLPPSHTLGMVKMMSQSVENRLILDQFRDSHFQLIFNTGLNNLDSQWAGLLIFDESGQILCANRRADTLLGTA
PAGASIETLFKCPILQLLSETEARPFALHAFGNNRFQCLLKRPTRKPLKLHCVQAAQVPAAPRNLDLQAISLGDAKVEKA
VRQAQRLLEKDIPLLIHGETGVGKEVFVKALHQASARASQPLIAVNCAAIPADLVEAELFGYERGAFTGANQKGSIGLIR
KADKGTLFLDEVGDMPMPVQARLLRVLQERCVQPLGSSELYPVDIRLISATNRGLRDQVQAGLFRQDLYYRISGLSIELP
PLRERTDKHALIQRIWERHRDAHQRAGFSREVLELFEHHPWPGNLRQLNSVIQVALALADEQPIGTDHLPEDFLLDAHAD
EECRVPLRTQESATRFHSSEDLGQLFQAAGGNVSQLAKRLGVSRNTLYKRLREQRIV
>Mature_616_residues
SQTSASLAHDIIIQDSWTRCRDFGLSHQTRPSFGQLPGTEVSRLLERHHGLVQTTHQEVLPVYENILSNSSCLILLADRQ
GQLLKSWGAQRFVESSQAQGFMPGASWNERGTGTNAIGTALACEEAIHIEPDEHFLKANRFMTGSASPIFDADRRIIAVL
DVSSDSFLPPSHTLGMVKMMSQSVENRLILDQFRDSHFQLIFNTGLNNLDSQWAGLLIFDESGQILCANRRADTLLGTAP
AGASIETLFKCPILQLLSETEARPFALHAFGNNRFQCLLKRPTRKPLKLHCVQAAQVPAAPRNLDLQAISLGDAKVEKAV
RQAQRLLEKDIPLLIHGETGVGKEVFVKALHQASARASQPLIAVNCAAIPADLVEAELFGYERGAFTGANQKGSIGLIRK
ADKGTLFLDEVGDMPMPVQARLLRVLQERCVQPLGSSELYPVDIRLISATNRGLRDQVQAGLFRQDLYYRISGLSIELPP
LRERTDKHALIQRIWERHRDAHQRAGFSREVLELFEHHPWPGNLRQLNSVIQVALALADEQPIGTDHLPEDFLLDAHADE
ECRVPLRTQESATRFHSSEDLGQLFQAAGGNVSQLAKRLGVSRNTLYKRLREQRIV

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=474, Percent_Identity=32.4894514767932, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1788905, Length=298, Percent_Identity=41.9463087248322, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1790437, Length=285, Percent_Identity=41.4035087719298, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1788550, Length=289, Percent_Identity=38.4083044982699, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=39.6875, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=38.5093167701863, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789087, Length=299, Percent_Identity=38.1270903010033, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082152, Length=343, Percent_Identity=38.1924198250729, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1790299, Length=348, Percent_Identity=36.2068965517241, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1787583, Length=306, Percent_Identity=38.2352941176471, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87081858, Length=630, Percent_Identity=24.7619047619048, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87081872, Length=219, Percent_Identity=40.6392694063927, Blast_Score=155, Evalue=9e-39,
Organism=Escherichia coli, GI1789828, Length=251, Percent_Identity=35.0597609561753, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68627; Mature: 68496

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTSASLAHDIIIQDSWTRCRDFGLSHQTRPSFGQLPGTEVSRLLERHHGLVQTTHQEV
CCCCHHHHHHHEEEECCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
LPVYENILSNSSCLILLADRQGQLLKSWGAQRFVESSQAQGFMPGASWNERGTGTNAIGT
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
ALACEEAIHIEPDEHFLKANRFMTGSASPIFDADRRIIAVLDVSSDSFLPPSHTLGMVKM
HHHHCCCEECCCHHHHHHHCCEECCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHH
MSQSVENRLILDQFRDSHFQLIFNTGLNNLDSQWAGLLIFDESGQILCANRRADTLLGTA
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEECCCCCHHEECC
PAGASIETLFKCPILQLLSETEARPFALHAFGNNRFQCLLKRPTRKPLKLHCVQAAQVPA
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCCC
APRNLDLQAISLGDAKVEKAVRQAQRLLEKDIPLLIHGETGVGKEVFVKALHQASARASQ
CCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCC
PLIAVNCAAIPADLVEAELFGYERGAFTGANQKGSIGLIRKADKGTLFLDEVGDMPMPVQ
CEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHCCCCCCCHH
ARLLRVLQERCVQPLGSSELYPVDIRLISATNRGLRDQVQAGLFRQDLYYRISGLSIELP
HHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEECCEEECC
PLRERTDKHALIQRIWERHRDAHQRAGFSREVLELFEHHPWPGNLRQLNSVIQVALALAD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
EQPIGTDHLPEDFLLDAHADEECRVPLRTQESATRFHSSEDLGQLFQAAGGNVSQLAKRL
CCCCCCCCCCHHHEEECCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHH
GVSRNTLYKRLREQRIV
CCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQTSASLAHDIIIQDSWTRCRDFGLSHQTRPSFGQLPGTEVSRLLERHHGLVQTTHQEV
CCCHHHHHHHEEEECCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
LPVYENILSNSSCLILLADRQGQLLKSWGAQRFVESSQAQGFMPGASWNERGTGTNAIGT
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
ALACEEAIHIEPDEHFLKANRFMTGSASPIFDADRRIIAVLDVSSDSFLPPSHTLGMVKM
HHHHCCCEECCCHHHHHHHCCEECCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHH
MSQSVENRLILDQFRDSHFQLIFNTGLNNLDSQWAGLLIFDESGQILCANRRADTLLGTA
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEECCCCCHHEECC
PAGASIETLFKCPILQLLSETEARPFALHAFGNNRFQCLLKRPTRKPLKLHCVQAAQVPA
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCCC
APRNLDLQAISLGDAKVEKAVRQAQRLLEKDIPLLIHGETGVGKEVFVKALHQASARASQ
CCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCC
PLIAVNCAAIPADLVEAELFGYERGAFTGANQKGSIGLIRKADKGTLFLDEVGDMPMPVQ
CEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHCCCCCCCHH
ARLLRVLQERCVQPLGSSELYPVDIRLISATNRGLRDQVQAGLFRQDLYYRISGLSIELP
HHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEECCEEECC
PLRERTDKHALIQRIWERHRDAHQRAGFSREVLELFEHHPWPGNLRQLNSVIQVALALAD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
EQPIGTDHLPEDFLLDAHADEECRVPLRTQESATRFHSSEDLGQLFQAAGGNVSQLAKRL
CCCCCCCCCCHHHEEECCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHH
GVSRNTLYKRLREQRIV
CCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]