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The map label for this gene is cysS [H]

Identifier: 66044980

GI number: 66044980

Start: 1970482

End: 1971864

Strand: Direct

Name: cysS [H]

Synonym: Psyr_1735

Alternate gene names: 66044980

Gene position: 1970482-1971864 (Clockwise)

Preceding gene: 66044979

Following gene: 66044982

Centisome position: 32.34

GC content: 61.03

Gene sequence:

>1383_bases
GTGCTTTCTATCTACAACACGCTCACCAAGAGCAAAGAAGTTTTCAAGCCGCTGGATGGCAACAAGGTGCGCATGTACGT
CTGCGGGATGACCGTGTACGACTACTGCCACCTGGGCCATGGCCGCAGTATGGTCGCGTTCGATCTGGTGACGCGCTGGC
TGCGCTTCAGCGGTTATGAACTGACCTATGTGCGCAACATTACCGATATCGACGACAAGATCATCAACCGGGCGCGGGAA
AACGGTGAGTCGTTCGACGCACTGACCGCGCGCATGATCGAGGCCATGCACGAGGACGAGGCGCGCCTCAACATCCTCAA
GCCGGACATGGAGCCGCGTGCCACCGACCATATCCCTGGCATGCACGCCATGATCCAGACCCTGATCGACAAGGGCTATG
CCTACGCGCCGGGTAACGGCGATGTGTATTACCGGGTCGGCAAGTTTCAGGGTTACGGCAAGCTGTCGCGCAAGAAGATC
GAAGACCTGCGCATCGGCGCACGTATCGAAGTGGACGAGTCCAAGGAAGATCCGCTGGACTTCGTCCTCTGGAAAGGCGT
CAAGCCGGGCGAGCCGAGCTGGGAATCGCCGTGGGGGGCAGGGCGTCCAGGCTGGCATATCGAGTGCTCGGTGATGTCGA
CCTGCTGCCTGGGCGAGACTTTCGATATTCATGGGGGCGGCAGCGATCTGGAGTTTCCGCACCATGAAAACGAAATCGCC
CAGAGCGAAGCGGCCACCGGCAAGACCTACGCCAATGCCTGGTTGCACTGCGGCATGATTCGTATCAATGGCGAGAAGAT
GTCCAAGTCCCTGAACAACTTCTTCACTATTCGCGACGTGCTGGAGAAATACCACCCTGAAGTGGTGCGTTACCTGCTGG
TGTCGAGCCACTACCGCAGCGCGATCAACTATTCCGAAGACAGCCTGCGTGAGTCGAAGGCGGCACTGGAGCGGTTCTAT
CACGCGCTCAAGGGCCTGCCGGTCGCCGAACCTGCGGGTGGCGAGGCGTTCGTCGAGCGTTTCAGCACGGCGATGAACGA
TGACTTCGGTACGCCTGAAGCCTGTGCGGTGCTGTTCGAGATGGTCCGCGAGATCAATCGTCTGCGCGAATCCGATATCG
CAGCAGCGGCGTGTCTGGCGGCGCGCTTGAAGCAACTGGCCAGCGTGCTGGGTGTCCTGCAACTCGAGGCCGACGACTTT
TTGCGCGCTGGCGCGGAAGGACGGGTCGATGCGGCTGAAGTGGAGGCGCTGATTCAGGCGCGTCTGGCTGCGCGTGCCGC
GAAAGACTGGGCCGAGTCCGACCGTATCCGCGACCGGATCACCGCCATGGGCGTGCTGCTGGAAGACGGCAAGGGCGGCA
CCACCTGGCGTCTGGCGGACTGA

Upstream 100 bases:

>100_bases
CGCGGACATCAAGGACTCCAGACCCGGTCGACCTGTCTTCAACCGCACCGTGACGTTGCGGGATTCCTGGACCTGATGCT
GTACGTTTGAGGGGGAGCAC

Downstream 100 bases:

>100_bases
TCAAGGACTATCCCTGAAATACTATCGTGCCCGTGCTCCGCATGGGCATGCTGTTCTGGACGCTCCGCGTCCTGTCCTCG
ATGTGCAGCCTGCCGAGCGT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLSIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYELTYVRNITDIDDKIINRARE
NGESFDALTARMIEAMHEDEARLNILKPDMEPRATDHIPGMHAMIQTLIDKGYAYAPGNGDVYYRVGKFQGYGKLSRKKI
EDLRIGARIEVDESKEDPLDFVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
QSEAATGKTYANAWLHCGMIRINGEKMSKSLNNFFTIRDVLEKYHPEVVRYLLVSSHYRSAINYSEDSLRESKAALERFY
HALKGLPVAEPAGGEAFVERFSTAMNDDFGTPEACAVLFEMVREINRLRESDIAAAACLAARLKQLASVLGVLQLEADDF
LRAGAEGRVDAAEVEALIQARLAARAAKDWAESDRIRDRITAMGVLLEDGKGGTTWRLAD

Sequences:

>Translated_460_residues
MLSIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYELTYVRNITDIDDKIINRARE
NGESFDALTARMIEAMHEDEARLNILKPDMEPRATDHIPGMHAMIQTLIDKGYAYAPGNGDVYYRVGKFQGYGKLSRKKI
EDLRIGARIEVDESKEDPLDFVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
QSEAATGKTYANAWLHCGMIRINGEKMSKSLNNFFTIRDVLEKYHPEVVRYLLVSSHYRSAINYSEDSLRESKAALERFY
HALKGLPVAEPAGGEAFVERFSTAMNDDFGTPEACAVLFEMVREINRLRESDIAAAACLAARLKQLASVLGVLQLEADDF
LRAGAEGRVDAAEVEALIQARLAARAAKDWAESDRIRDRITAMGVLLEDGKGGTTWRLAD
>Mature_460_residues
MLSIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYELTYVRNITDIDDKIINRARE
NGESFDALTARMIEAMHEDEARLNILKPDMEPRATDHIPGMHAMIQTLIDKGYAYAPGNGDVYYRVGKFQGYGKLSRKKI
EDLRIGARIEVDESKEDPLDFVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
QSEAATGKTYANAWLHCGMIRINGEKMSKSLNNFFTIRDVLEKYHPEVVRYLLVSSHYRSAINYSEDSLRESKAALERFY
HALKGLPVAEPAGGEAFVERFSTAMNDDFGTPEACAVLFEMVREINRLRESDIAAAACLAARLKQLASVLGVLQLEADDF
LRAGAEGRVDAAEVEALIQARLAARAAKDWAESDRIRDRITAMGVLLEDGKGGTTWRLAD

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=390, Percent_Identity=38.4615384615385, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI62240992, Length=238, Percent_Identity=42.8571428571429, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI10835051, Length=238, Percent_Identity=42.8571428571429, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI303304987, Length=238, Percent_Identity=42.8571428571429, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI21269877, Length=238, Percent_Identity=42.8571428571429, Blast_Score=197, Evalue=2e-50,
Organism=Escherichia coli, GI1786737, Length=459, Percent_Identity=60.3485838779956, Blast_Score=554, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17509797, Length=446, Percent_Identity=32.0627802690583, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17509795, Length=446, Percent_Identity=32.0627802690583, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324082, Length=327, Percent_Identity=36.3914373088685, Blast_Score=213, Evalue=7e-56,
Organism=Drosophila melanogaster, GI19922218, Length=504, Percent_Identity=33.531746031746, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI19922364, Length=277, Percent_Identity=40.072202166065, Blast_Score=192, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51565; Mature: 51565

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYE
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCE
LTYVRNITDIDDKIINRARENGESFDALTARMIEAMHEDEARLNILKPDMEPRATDHIPG
EEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCH
MHAMIQTLIDKGYAYAPGNGDVYYRVGKFQGYGKLSRKKIEDLRIGARIEVDESKEDPLD
HHHHHHHHHHCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCC
FVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
EEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCEEECCCCCCCCCCCCHHHHH
QSEAATGKTYANAWLHCGMIRINGEKMSKSLNNFFTIRDVLEKYHPEVVRYLLVSSHYRS
HHHHCCCCHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AINYSEDSLRESKAALERFYHALKGLPVAEPAGGEAFVERFSTAMNDDFGTPEACAVLFE
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
MVREINRLRESDIAAAACLAARLKQLASVLGVLQLEADDFLRAGAEGRVDAAEVEALIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHH
RLAARAAKDWAESDRIRDRITAMGVLLEDGKGGTTWRLAD
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECC
>Mature Secondary Structure
MLSIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYE
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCE
LTYVRNITDIDDKIINRARENGESFDALTARMIEAMHEDEARLNILKPDMEPRATDHIPG
EEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCH
MHAMIQTLIDKGYAYAPGNGDVYYRVGKFQGYGKLSRKKIEDLRIGARIEVDESKEDPLD
HHHHHHHHHHCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCC
FVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
EEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCEEECCCCCCCCCCCCHHHHH
QSEAATGKTYANAWLHCGMIRINGEKMSKSLNNFFTIRDVLEKYHPEVVRYLLVSSHYRS
HHHHCCCCHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AINYSEDSLRESKAALERFYHALKGLPVAEPAGGEAFVERFSTAMNDDFGTPEACAVLFE
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
MVREINRLRESDIAAAACLAARLKQLASVLGVLQLEADDFLRAGAEGRVDAAEVEALIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHH
RLAARAAKDWAESDRIRDRITAMGVLLEDGKGGTTWRLAD
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA