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The map label for this gene is glnS [H]

Identifier: 66044979

GI number: 66044979

Start: 1968763

End: 1970457

Strand: Direct

Name: glnS [H]

Synonym: Psyr_1734

Alternate gene names: 66044979

Gene position: 1968763-1970457 (Clockwise)

Preceding gene: 66044976

Following gene: 66044980

Centisome position: 32.31

GC content: 60.12

Gene sequence:

>1695_bases
ATGAGCAAGCCCACTCCAGAACCCGCTGCCCATTCAAAGGCAGGTCCAGCCGTACCGACCAATTTCCTGCGTCCTATCGT
GCAGGCAGACCTGGACTCGGGCAAGCACAGCAAAATCGTGACCCGCTTTCCGCCGGAGCCCAACGGCTACCTGCACATCG
GTCACGCCAAGTCGATCTGCGTGAACTTCGGTCTGGCCCAGGAGTTCGGTGGCGATACGCACCTGCGTTTCGATGACACC
AACCCGGCCAAGGAAGACCAGGAATACATCGACGCCATCATGAGTGACGTCAAGTGGCTGGGCTTCGAGTGGGCGGGCGA
AGTGCGCTACGCCTCGCAGTATTTCGACCAGTTGCACGACTGGGCGGTCGAGCTGATCAAGGCAGGCAAGGCCTATGTGG
ACGATCTGACCCCCGAGCAGGCGCGCGAATATCGCGGCACCCTGACCGAGCCGGGCAAGAACAGTCCGTTCCGCGAGCGT
AGCGTCGAGGAAAACCTCGACCTGTTCGCGCGCATGAAAGCCGGTGAGTTCGAGGATGGCGCTCGCGTACTGCGCGCCAA
AATCGACATGGCCTCGCCGAACATGAACCTGCGTGACCCGATCATCTACCGCATTCGCCATGCGCATCACCATCAGACCG
GCGACAAGTGGTGCATCTATCCGATCTATGACTTCACCCACGGTCAGTCGGATGCCCTCGAAGGCATCACCCACTCGATC
TGCACCCTGGAGTTCGAAAGCCATCGTCCGCTGTACGACTGGTTTCTCGACAACCTGCCGGTGCCGTGCAAGCCGCGTCA
GTATGAGTTCTCGCGCCTGAACCTGAACTACACCATCACCAGCAAGCGCAAGCTCAAGCAACTGGTTGACGAGAAACACG
TCAATGGCTGGGATGACCCACGCATGTCGACGCTGTCGGGCTTCCGTCGCCGTGGCTACACGCCCAAATCGATTCGCAAT
TTCTGCGAAATGATCGGCACCAACCGCTCTGATGGCGTGGTCGATTTCGGCATGCTCGAATTCAGCATCCGCGACGACCT
GGACCACAGCGCGCCGCGCGCCATGTGCGTGCTGCGCCCGCTGAAAGTGGTCATCACCAACTACCCGGAAGGCCAGGTCG
AGAAGCTGGAACTGCCGCGCCACCCGAAAGAAGATCTGGGCATGCGCGAGCTGCCGTTCTCGCGGGAGCTGTACATCGAT
CGCGACGATTACATGGAAGAGCCGCCGAAGGGCTACAAGCGTCTTGAGCCCAACGGCGAAGTGCGTTTGCGTGGCAGCTA
TGTGATCCGTGCCGATGAAGCGATCAAGGATGCCGACGGCAACATCGTCGAGCTGCGTTGCTCCTACGACCCGGAAACGT
TGGGCAAGAACCCTGAAGGCCGCAAGGTCAAGGGCGTCGTGCACTGGGTGCCGGCAGCCGAGAGCGTAGAGTGCGAAGTG
CGTCTGTACGATCGTCTGTTCCGTTCGCCGAACCCTGAAAAAGCCGAAGAGGGCGCAAGCTTTCTGGACAACATCAACCC
GGACTCCCTGCAAGTACTGACCGGTTGTCGCGCCGAGCCTTCATTGGCGCAAGCGCAACCGGAAGACCGTTTCCAGTTCG
AACGCGAAGGTTATTTCTGCGCGGACATCAAGGACTCCAGACCCGGTCGACCTGTCTTCAACCGCACCGTGACGTTGCGG
GATTCCTGGACCTGA

Upstream 100 bases:

>100_bases
AAATACGCAGTCTGTTGTCAGGGACTTGACAGCTTCGGCTATGATAAGCGCTTTGATTTAGTCGGCCTACCCTGGCCGCG
CACGTATGTCCAAGGATCCT

Downstream 100 bases:

>100_bases
TGCTGTACGTTTGAGGGGGAGCACGTGCTTTCTATCTACAACACGCTCACCAAGAGCAAAGAAGTTTTCAAGCCGCTGGA
TGGCAACAAGGTGCGCATGT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MSKPTPEPAAHSKAGPAVPTNFLRPIVQADLDSGKHSKIVTRFPPEPNGYLHIGHAKSICVNFGLAQEFGGDTHLRFDDT
NPAKEDQEYIDAIMSDVKWLGFEWAGEVRYASQYFDQLHDWAVELIKAGKAYVDDLTPEQAREYRGTLTEPGKNSPFRER
SVEENLDLFARMKAGEFEDGARVLRAKIDMASPNMNLRDPIIYRIRHAHHHQTGDKWCIYPIYDFTHGQSDALEGITHSI
CTLEFESHRPLYDWFLDNLPVPCKPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDPRMSTLSGFRRRGYTPKSIRN
FCEMIGTNRSDGVVDFGMLEFSIRDDLDHSAPRAMCVLRPLKVVITNYPEGQVEKLELPRHPKEDLGMRELPFSRELYID
RDDYMEEPPKGYKRLEPNGEVRLRGSYVIRADEAIKDADGNIVELRCSYDPETLGKNPEGRKVKGVVHWVPAAESVECEV
RLYDRLFRSPNPEKAEEGASFLDNINPDSLQVLTGCRAEPSLAQAQPEDRFQFEREGYFCADIKDSRPGRPVFNRTVTLR
DSWT

Sequences:

>Translated_564_residues
MSKPTPEPAAHSKAGPAVPTNFLRPIVQADLDSGKHSKIVTRFPPEPNGYLHIGHAKSICVNFGLAQEFGGDTHLRFDDT
NPAKEDQEYIDAIMSDVKWLGFEWAGEVRYASQYFDQLHDWAVELIKAGKAYVDDLTPEQAREYRGTLTEPGKNSPFRER
SVEENLDLFARMKAGEFEDGARVLRAKIDMASPNMNLRDPIIYRIRHAHHHQTGDKWCIYPIYDFTHGQSDALEGITHSI
CTLEFESHRPLYDWFLDNLPVPCKPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDPRMSTLSGFRRRGYTPKSIRN
FCEMIGTNRSDGVVDFGMLEFSIRDDLDHSAPRAMCVLRPLKVVITNYPEGQVEKLELPRHPKEDLGMRELPFSRELYID
RDDYMEEPPKGYKRLEPNGEVRLRGSYVIRADEAIKDADGNIVELRCSYDPETLGKNPEGRKVKGVVHWVPAAESVECEV
RLYDRLFRSPNPEKAEEGASFLDNINPDSLQVLTGCRAEPSLAQAQPEDRFQFEREGYFCADIKDSRPGRPVFNRTVTLR
DSWT
>Mature_563_residues
SKPTPEPAAHSKAGPAVPTNFLRPIVQADLDSGKHSKIVTRFPPEPNGYLHIGHAKSICVNFGLAQEFGGDTHLRFDDTN
PAKEDQEYIDAIMSDVKWLGFEWAGEVRYASQYFDQLHDWAVELIKAGKAYVDDLTPEQAREYRGTLTEPGKNSPFRERS
VEENLDLFARMKAGEFEDGARVLRAKIDMASPNMNLRDPIIYRIRHAHHHQTGDKWCIYPIYDFTHGQSDALEGITHSIC
TLEFESHRPLYDWFLDNLPVPCKPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDPRMSTLSGFRRRGYTPKSIRNF
CEMIGTNRSDGVVDFGMLEFSIRDDLDHSAPRAMCVLRPLKVVITNYPEGQVEKLELPRHPKEDLGMRELPFSRELYIDR
DDYMEEPPKGYKRLEPNGEVRLRGSYVIRADEAIKDADGNIVELRCSYDPETLGKNPEGRKVKGVVHWVPAAESVECEVR
LYDRLFRSPNPEKAEEGASFLDNINPDSLQVLTGCRAEPSLAQAQPEDRFQFEREGYFCADIKDSRPGRPVFNRTVTLRD
SWT

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=527, Percent_Identity=45.73055028463, Blast_Score=447, Evalue=1e-125,
Organism=Homo sapiens, GI62241042, Length=527, Percent_Identity=32.8273244781784, Blast_Score=263, Evalue=3e-70,
Organism=Escherichia coli, GI1786895, Length=550, Percent_Identity=62.3636363636364, Blast_Score=718, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=311, Percent_Identity=26.3665594855305, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=530, Percent_Identity=44.7169811320755, Blast_Score=439, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17511007, Length=525, Percent_Identity=31.2380952380952, Blast_Score=228, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6324742, Length=564, Percent_Identity=39.8936170212766, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321192, Length=558, Percent_Identity=35.3046594982079, Blast_Score=304, Evalue=2e-83,
Organism=Drosophila melanogaster, GI17864488, Length=528, Percent_Identity=44.5075757575758, Blast_Score=439, Evalue=1e-123,
Organism=Drosophila melanogaster, GI24649466, Length=525, Percent_Identity=34.8571428571429, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24665321, Length=316, Percent_Identity=25.3164556962025, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64713; Mature: 64582

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPTPEPAAHSKAGPAVPTNFLRPIVQADLDSGKHSKIVTRFPPEPNGYLHIGHAKSIC
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEECCHHEEH
VNFGLAQEFGGDTHLRFDDTNPAKEDQEYIDAIMSDVKWLGFEWAGEVRYASQYFDQLHD
EECCHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHH
WAVELIKAGKAYVDDLTPEQAREYRGTLTEPGKNSPFRERSVEENLDLFARMKAGEFEDG
HHHHHHHHCCHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
ARVLRAKIDMASPNMNLRDPIIYRIRHAHHHQTGDKWCIYPIYDFTHGQSDALEGITHSI
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHE
CTLEFESHRPLYDWFLDNLPVPCKPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDP
EEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHCCCCCCCC
RMSTLSGFRRRGYTPKSIRNFCEMIGTNRSDGVVDFGMLEFSIRDDLDHSAPRAMCVLRP
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHH
LKVVITNYPEGQVEKLELPRHPKEDLGMRELPFSRELYIDRDDYMEEPPKGYKRLEPNGE
HHHEEECCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEECCHHHCCCCCCCHHCCCCCCC
VRLRGSYVIRADEAIKDADGNIVELRCSYDPETLGKNPEGRKVKGVVHWVPAAESVECEV
EEEECEEEEEECHHHHCCCCCEEEEEECCCHHHCCCCCCCCEEEEEEEEECCCCCCEEHH
RLYDRLFRSPNPEKAEEGASFLDNINPDSLQVLTGCRAEPSLAQAQPEDRFQFEREGYFC
HHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHCCCHHHCCHHCCCEEE
ADIKDSRPGRPVFNRTVTLRDSWT
EECCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SKPTPEPAAHSKAGPAVPTNFLRPIVQADLDSGKHSKIVTRFPPEPNGYLHIGHAKSIC
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEECCHHEEH
VNFGLAQEFGGDTHLRFDDTNPAKEDQEYIDAIMSDVKWLGFEWAGEVRYASQYFDQLHD
EECCHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHH
WAVELIKAGKAYVDDLTPEQAREYRGTLTEPGKNSPFRERSVEENLDLFARMKAGEFEDG
HHHHHHHHCCHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
ARVLRAKIDMASPNMNLRDPIIYRIRHAHHHQTGDKWCIYPIYDFTHGQSDALEGITHSI
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHE
CTLEFESHRPLYDWFLDNLPVPCKPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDP
EEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHCCCCCCCC
RMSTLSGFRRRGYTPKSIRNFCEMIGTNRSDGVVDFGMLEFSIRDDLDHSAPRAMCVLRP
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHH
LKVVITNYPEGQVEKLELPRHPKEDLGMRELPFSRELYIDRDDYMEEPPKGYKRLEPNGE
HHHEEECCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEECCHHHCCCCCCCHHCCCCCCC
VRLRGSYVIRADEAIKDADGNIVELRCSYDPETLGKNPEGRKVKGVVHWVPAAESVECEV
EEEECEEEEEECHHHHCCCCCEEEEEECCCHHHCCCCCCCCEEEEEEEEECCCCCCEEHH
RLYDRLFRSPNPEKAEEGASFLDNINPDSLQVLTGCRAEPSLAQAQPEDRFQFEREGYFC
HHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHCCCHHHCCHHCCCEEE
ADIKDSRPGRPVFNRTVTLRDSWT
EECCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]