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The map label for this gene is 66044939

Identifier: 66044939

GI number: 66044939

Start: 1902263

End: 1902817

Strand: Direct

Name: 66044939

Synonym: Psyr_1694

Alternate gene names: NA

Gene position: 1902263-1902817 (Clockwise)

Preceding gene: 66044938

Following gene: 66044940

Centisome position: 31.22

GC content: 59.1

Gene sequence:

>555_bases
ATGGCGTTTTCCCGACGACTCAAGGTCATCCTCGTCCTGTCGGCCGTGTTGATTGCGGTACAGGCATTCAACTCGATGAC
CAGCAACAGTCTGCTGCAGTTCGGTATCATGCCGCGCAGCCTCACCGGGTTGCGCGGCATTGTGTTTGCCCCCTTTTTGC
ACGGGTCGATTCAGCACTTGCTCAGCAATCTGTTGCCGTTCATTGTGCTGAGCTGGCTGGTGGCGACCGAGGGTGTCAGG
CGTTATGCATGGGTCGCCGGGCTGGTTTGCCTGCTGGGCGGACTGCTGGTCTGGAGCTTCGGTCGCAGCAATATTCATGT
CGGCGCAAGTGGTCTGATTTTTGGTTTGTGGGCTTATCTGCTGGCGCGGGCGTGGTATCAGCGCAGTATCGCCAGTGTGC
TGATCGCGCTGCTGGTGCTGGCCGCTTACAGCGGGCTGGTGTTCGGCTTCGTTCCGGTGGCCGGTGTGTCGTTCGAATCA
CATATCGCGGGTGCACTTGCAGGCGTTTGTGTGGCCTGGCTGATGCATTCCAGGGCATTGCTGGCGCAGAAATGA

Upstream 100 bases:

>100_bases
TGCTAAAAGCGGCGGTGCGCAAGATGTACTGGCGCGCCTGAAAGCCAAAAGTCAGACGCCGGCTCAGTAAGCGCTGCAAC
AAGGCAGGCGAGGGTGGTGC

Downstream 100 bases:

>100_bases
GTCAGTCTCGCGCTTGCAGGCAGTGCGCCTGTTGCGCTTGAAGAGCGTTATATATCGTCACCCGTCACTGCAAGGAAACG
GATTATGAGTTGGTTCAAAC

Product: rhomboid-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MAFSRRLKVILVLSAVLIAVQAFNSMTSNSLLQFGIMPRSLTGLRGIVFAPFLHGSIQHLLSNLLPFIVLSWLVATEGVR
RYAWVAGLVCLLGGLLVWSFGRSNIHVGASGLIFGLWAYLLARAWYQRSIASVLIALLVLAAYSGLVFGFVPVAGVSFES
HIAGALAGVCVAWLMHSRALLAQK

Sequences:

>Translated_184_residues
MAFSRRLKVILVLSAVLIAVQAFNSMTSNSLLQFGIMPRSLTGLRGIVFAPFLHGSIQHLLSNLLPFIVLSWLVATEGVR
RYAWVAGLVCLLGGLLVWSFGRSNIHVGASGLIFGLWAYLLARAWYQRSIASVLIALLVLAAYSGLVFGFVPVAGVSFES
HIAGALAGVCVAWLMHSRALLAQK
>Mature_183_residues
AFSRRLKVILVLSAVLIAVQAFNSMTSNSLLQFGIMPRSLTGLRGIVFAPFLHGSIQHLLSNLLPFIVLSWLVATEGVRR
YAWVAGLVCLLGGLLVWSFGRSNIHVGASGLIFGLWAYLLARAWYQRSIASVLIALLVLAAYSGLVFGFVPVAGVSFESH
IAGALAGVCVAWLMHSRALLAQK

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 19823; Mature: 19692

Theoretical pI: Translated: 11.69; Mature: 11.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSRRLKVILVLSAVLIAVQAFNSMTSNSLLQFGIMPRSLTGLRGIVFAPFLHGSIQHL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSNLLPFIVLSWLVATEGVRRYAWVAGLVCLLGGLLVWSFGRSNIHVGASGLIFGLWAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHH
LARAWYQRSIASVLIALLVLAAYSGLVFGFVPVAGVSFESHIAGALAGVCVAWLMHSRAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQK
HHCC
>Mature Secondary Structure 
AFSRRLKVILVLSAVLIAVQAFNSMTSNSLLQFGIMPRSLTGLRGIVFAPFLHGSIQHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSNLLPFIVLSWLVATEGVRRYAWVAGLVCLLGGLLVWSFGRSNIHVGASGLIFGLWAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHH
LARAWYQRSIASVLIALLVLAAYSGLVFGFVPVAGVSFESHIAGALAGVCVAWLMHSRAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]