| Definition | Pseudomonas syringae pv. syringae B728a, complete genome. |
|---|---|
| Accession | NC_007005 |
| Length | 6,093,698 |
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The map label for this gene is fabG [C]
Identifier: 66044915
GI number: 66044915
Start: 1875192
End: 1876010
Strand: Direct
Name: fabG [C]
Synonym: Psyr_1670
Alternate gene names: 66044915
Gene position: 1875192-1876010 (Clockwise)
Preceding gene: 66044914
Following gene: 66044916
Centisome position: 30.77
GC content: 64.1
Gene sequence:
>819_bases GTGAGTAGCGAGGCCAGCAATCCGGCCAGTGGCAAGCCGGGCGAGGAGTGGGCGTTGAAATTTGCCAGTGTCCACAACGG TCGTGTCGCTCTGGTGACCGGTGCCGCTCGCGGTATCGGGCTCGGCATTGCAGCGTGGCTGATTGCCGAAGGCTGGCAAG TGGTGCTGACCGATCTGGATCGTGCGCGTGGCTCGAAAGTGGCTGGTGCGCTGGGTGAAAATGCCCTGTTCATTGCCATG GACGTTGCCAGTGAAGAGCAGGTCGCAGCGGGCGTGGCCGAGGTGCTTCGGCAGTTCGGTCGTCTCGATGCGCTGGTGTG CAACGCTGCGATCGCCGACCCGCACAACACGACGCTGGAAAGCCTTGAGCTGTCGCACTGGAACCGTGTGCTGGCAGTCA ACCTCGGCGGTCCGATGCTGCTGGCCAAGCATTGTGCGCCATACCTGCGTGCGCATTGCGGCAGCATCGTCAACCTGACC TCCACACGCTCTCGCCAGTCGGAGGCCGATACCGAAGCTTATGCAGCCAGCAAGGGCGGTCTTATGGCGCTGACACATGC GCTGGCGATCAGCCTGGGGCCGGAGATTCGCGTCAACGCTGTCAGCCCTGGCTGGATCGACGCGCGTGACCCCTCGTTGC GCAGAGCCGAGCCGTTGTCCGAGACCGATCATGCCCAGCACCCGGCCGGCAGGGTAGGGACGGTGGAGGATGTTGCGGCG ATGGTTGCCTGGCTGTTGTCCAGAAACGCCGGTTTCGTCACCGGGCAGGAGTTCGTGGTCGACGGCGGCATGACGCGCAA GATGGTGTACGCCGAGTAG
Upstream 100 bases:
>100_bases GTGAAGCCGCAGGTATTCGCGACAGCCTGATTCGGGTTGCAGTGGGGCTGGAAGACCTGGCTGACCTGCAGGCTGACCTG GCTCGTGGTCTGGCGGCGTT
Downstream 100 bases:
>100_bases TTTGCGCGGGCGAGCTTCGATTGAGCTATTGCTTGTGCTTTTGGTGTGTGGTGAGGGTTTTGTGATTGAGGCGGTTTTTA AAAAAACTTCAATCAGGCTA
Product: oxidoreductase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 272; Mature: 271
Protein sequence:
>272_residues MSSEASNPASGKPGEEWALKFASVHNGRVALVTGAARGIGLGIAAWLIAEGWQVVLTDLDRARGSKVAGALGENALFIAM DVASEEQVAAGVAEVLRQFGRLDALVCNAAIADPHNTTLESLELSHWNRVLAVNLGGPMLLAKHCAPYLRAHCGSIVNLT STRSRQSEADTEAYAASKGGLMALTHALAISLGPEIRVNAVSPGWIDARDPSLRRAEPLSETDHAQHPAGRVGTVEDVAA MVAWLLSRNAGFVTGQEFVVDGGMTRKMVYAE
Sequences:
>Translated_272_residues MSSEASNPASGKPGEEWALKFASVHNGRVALVTGAARGIGLGIAAWLIAEGWQVVLTDLDRARGSKVAGALGENALFIAM DVASEEQVAAGVAEVLRQFGRLDALVCNAAIADPHNTTLESLELSHWNRVLAVNLGGPMLLAKHCAPYLRAHCGSIVNLT STRSRQSEADTEAYAASKGGLMALTHALAISLGPEIRVNAVSPGWIDARDPSLRRAEPLSETDHAQHPAGRVGTVEDVAA MVAWLLSRNAGFVTGQEFVVDGGMTRKMVYAE >Mature_271_residues SSEASNPASGKPGEEWALKFASVHNGRVALVTGAARGIGLGIAAWLIAEGWQVVLTDLDRARGSKVAGALGENALFIAMD VASEEQVAAGVAEVLRQFGRLDALVCNAAIADPHNTTLESLELSHWNRVLAVNLGGPMLLAKHCAPYLRAHCGSIVNLTS TRSRQSEADTEAYAASKGGLMALTHALAISLGPEIRVNAVSPGWIDARDPSLRRAEPLSETDHAQHPAGRVGTVEDVAAM VAWLLSRNAGFVTGQEFVVDGGMTRKMVYAE
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=33.739837398374, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=35.3982300884956, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=34, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI10190704, Length=244, Percent_Identity=31.1475409836066, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=29.8804780876494, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI31542939, Length=228, Percent_Identity=30.7017543859649, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=32.3651452282158, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=30.6772908366534, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI4758504, Length=193, Percent_Identity=34.7150259067358, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=34.9462365591398, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=34.4444444444444, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI224922801, Length=191, Percent_Identity=33.5078534031414, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=32.6693227091633, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=27.8225806451613, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI20149619, Length=205, Percent_Identity=28.780487804878, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI40254986, Length=203, Percent_Identity=30.5418719211823, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=31.9672131147541, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=28.6885245901639, Blast_Score=97, Evalue=2e-21, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=28.1746031746032, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=33.6032388663968, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=29.0983606557377, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=30.952380952381, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=33.0612244897959, Blast_Score=86, Evalue=4e-18, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=28.4584980237154, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=30.6201550387597, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=28.5140562248996, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=28.1853281853282, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787891, Length=240, Percent_Identity=27.5, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1788891, Length=197, Percent_Identity=32.48730964467, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=27.2357723577236, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787526, Length=241, Percent_Identity=25.3112033195021, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=31.1284046692607, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=30.2788844621514, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=30.7116104868914, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.5660377358491, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.0395256916996, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=28.6821705426357, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=29.6153846153846, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=28.0155642023346, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=30.9236947791165, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=31.9672131147541, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=30.3149606299213, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28.8, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=29.2307692307692, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=29.7709923664122, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=26.4591439688716, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560220, Length=257, Percent_Identity=27.2373540856031, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=27.6923076923077, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17555706, Length=267, Percent_Identity=30.3370786516854, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=30.3501945525292, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=27.2030651340996, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=26.0536398467433, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=29.2592592592593, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=26.8939393939394, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=32.6612903225806, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=28.6821705426357, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=28.6792452830189, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=28.6274509803922, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71982365, Length=138, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=31.2252964426877, Blast_Score=94, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6322227, Length=195, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6322226, Length=186, Percent_Identity=26.3440860215054, Blast_Score=65, Evalue=8e-12, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=35.0597609561753, Blast_Score=119, Evalue=1e-27, Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=35.3909465020576, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=34.5528455284553, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=30.7377049180328, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=32.7935222672065, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.9236947791165, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI17737361, Length=191, Percent_Identity=31.413612565445, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24644337, Length=176, Percent_Identity=36.9318181818182, Blast_Score=81, Evalue=8e-16, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24665243, Length=170, Percent_Identity=30.5882352941176, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI221331218, Length=170, Percent_Identity=30.5882352941176, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 28626; Mature: 28495
Theoretical pI: Translated: 6.09; Mature: 6.09
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSEASNPASGKPGEEWALKFASVHNGRVALVTGAARGIGLGIAAWLIAEGWQVVLTDLD CCCCCCCCCCCCCCHHHHHHHEEECCCEEEEEECCCCCHHHHHHHHHHHCCHHEEEEHHH RARGSKVAGALGENALFIAMDVASEEQVAAGVAEVLRQFGRLDALVCNAAIADPHNTTLE HHCCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHH SLELSHWNRVLAVNLGGPMLLAKHCAPYLRAHCGSIVNLTSTRSRQSEADTEAYAASKGG HHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCC LMALTHALAISLGPEIRVNAVSPGWIDARDPSLRRAEPLSETDHAQHPAGRVGTVEDVAA HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH MVAWLLSRNAGFVTGQEFVVDGGMTRKMVYAE HHHHHHHCCCCCCCCCEEEEECCCCCEEEECC >Mature Secondary Structure SSEASNPASGKPGEEWALKFASVHNGRVALVTGAARGIGLGIAAWLIAEGWQVVLTDLD CCCCCCCCCCCCCHHHHHHHEEECCCEEEEEECCCCCHHHHHHHHHHHCCHHEEEEHHH RARGSKVAGALGENALFIAMDVASEEQVAAGVAEVLRQFGRLDALVCNAAIADPHNTTLE HHCCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHH SLELSHWNRVLAVNLGGPMLLAKHCAPYLRAHCGSIVNLTSTRSRQSEADTEAYAASKGG HHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCC LMALTHALAISLGPEIRVNAVSPGWIDARDPSLRRAEPLSETDHAQHPAGRVGTVEDVAA HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH MVAWLLSRNAGFVTGQEFVVDGGMTRKMVYAE HHHHHHHCCCCCCCCCEEEEECCCCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7934833; 10984043 [H]