Click here to switch to the map view.

The map label for this gene is ptrB [H]

Identifier: 66044819

GI number: 66044819

Start: 1768583

End: 1770643

Strand: Reverse

Name: ptrB [H]

Synonym: Psyr_1574

Alternate gene names: 66044819

Gene position: 1770643-1768583 (Counterclockwise)

Preceding gene: 66044823

Following gene: 66044818

Centisome position: 29.06

GC content: 63.17

Gene sequence:

>2061_bases
ATGTCCTTCCCGAATGCAACCTCCAGCGCCCCGATCGCTCGCAAGGCCGACGGTTCCGACCCCTACGCCTGGCTGCAGAA
CCGCGACACCGACGAAGTGCTCGACTACCTCAAAGCCGAAAACGCCTGGCAGGAGCAGCAACTGGCAGAGCAGACCGGGT
TGCGCGAAAGCCTGTTCGAGGAAATCAAGGGCCGCATCCTCGAAACCGACCTGTCGCTGCCCTCCCCCTGGGGCCCTTAC
CTTTATTACACCCGCACCACACAAGGCGATGAATACGCCCGGCACTACCGCTGCCCGCGCCCGGCCGACGACAGCAACAC
AGTGGACGAAAGCGCTGAGGAATTGTTGCTCGACCCTAACGAGATGGCCGATGGCGGCTTTTTCTCGCTGGGCGCGTTCA
GCATCAGTCCCGACCACCAGCGCCTGGCCTACAGCCTGGACACCAGTGGCGACGAGGTGTACGCGCTTTACGTCAAGGAG
CTGAGCACCGGCCAGATCAGCAGCCTGCCCTTTGAAAACTGCGACGGCAGCATGACCTGGGCCAACGACAGCCAGACCCT
GTTTTTCGGCGAGCTGGACGAAACCCATCGCCCGGGCAGGCTGCATCGCCATACCCTGGGCACGGCATCAGCCGAGCTGG
TGTTCGACGAGCCGGACGGCCGCTTCTTCCTGCACTGTTTCCGCAGCAGCTCCGAGCGCCAACTGATCATTCTGCTCAAC
AGCAAAACCACTAGCGAAGCCTGGGTGCTGGACGCCGATCATCCACAACAGGCCTTCACCTGCCTCGCACCGCGCAGCGA
AGGTCACGAATATTACCCGGACCACGGGCTGCTCGACGGCGTCTGGACCTGGTTCATCCGCAGCAATCAGAGCGGCATCA
ACTTCGCGCTGTATCAGGCTGCGCAACAGGACAGTGGCGTACCGGTGCGCGAGGACTGGCAGACGCTGGTCGCGCACAAC
GACAAGGTCATGCTCGAAGGCGTCAGCCTCAACGCCAAAGGCATCAGCCTGAGCCTGCGCGAGGGCGGCCTGCCGATCAT
CGAAGTACGTCCGCAAGCGCTGCCGACCTATCGCGTGCAGCTGCCTGACGCCGCCTACAGCCTGTATGTGCAGGACACGC
TGGAATTCGACAGCGACAAAATCCGCCTGCGCTACCAGTCGCTGAACCGTCCGGCCCAGGTCCGTCAACTGACCCTGGCC
AGCGGCGAGCAAGTGGTGCTCAAGGAAACGCCGGTACTGGGCACCTTCGACGCCGATGCCTACGTCAGCCAGCGTTTGTG
GGCCACGGCCAGCGATGGCACCCAGGTGCCGATCAGCCTGGTGGTCAAGCGCGAACTGGCCGGACAGGCCACCCCGCTGT
ACCTGTACGGCTACGGCGCCTACGGCGAGAGCCTCGACCCGTGGTTTTCCCACGCGCGCCTGAGCCTGCTCGACCGTGGC
GTGGCGTTCGCCATCGCCCATGTGCGCGGCGGCGGCGAGCTGGGCGAGGCCTGGTATCGCAACGGCAAGCAGGAGCACAA
ACAGAACACTTTCGGCGATTTCATTGCCTGCGCCGAACACCTTGTTGCCCAGGGCCTGACCAGCGCCGGACAACTGGTGA
TCAGCGGTGGCAGCGCCGGTGGCCTGCTGATCGGTGCGGTGCTCAACCAACGGCCCGAGCTGTTCAAGGCAGCGATTGCC
GAAGTGCCGTTCGTCGATGTACTGAACACCATGCTCGACCCGGACCTGCCGCTGACCGTCACCGAATACGACGAATGGGG
CAACCCGCAGGAGCCGGAGGTCTACGCGCGTATCAAGGCCTACGCGCCCTACGAAAACGTCACGGCTCAGGCCTATCCGG
CCATGCTGGTCATCGCCGGTTACAACGACAGCCGTGTGCAGTATTGGGAAGCCGCCAAATGGGTGGCTAAATTGCGCGCC
ACCAAGACCGACGATAATCCGTTGCTGCTCAAGACCGAACTGGGCGCCGGGCACGGTGGCATGAGCGGTCGCTATCAGGG
CTTGCGTGACGTGGCGCTGGAGTACGCATTTATCTTCAAGGTATTGCAGATCGCTGAATGA

Upstream 100 bases:

>100_bases
TATGATAACGGCTTTTGCCTGACGCGGCTTGCCTCGCTTCAGTATTCGGTTCAGCGTGTACCGATATTTTCCTGATTGAT
GCCTTAACAGAGAGCCCAGC

Downstream 100 bases:

>100_bases
ACTTGGTGTGAAACACCTGTCTTACTAGGATCGGGGGCAGCGGAGTTGCCCCTTTGTCAGGATTACCAGACCTAACATGT
CAGAACCACTGTCCAACCTG

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MSFPNATSSAPIARKADGSDPYAWLQNRDTDEVLDYLKAENAWQEQQLAEQTGLRESLFEEIKGRILETDLSLPSPWGPY
LYYTRTTQGDEYARHYRCPRPADDSNTVDESAEELLLDPNEMADGGFFSLGAFSISPDHQRLAYSLDTSGDEVYALYVKE
LSTGQISSLPFENCDGSMTWANDSQTLFFGELDETHRPGRLHRHTLGTASAELVFDEPDGRFFLHCFRSSSERQLIILLN
SKTTSEAWVLDADHPQQAFTCLAPRSEGHEYYPDHGLLDGVWTWFIRSNQSGINFALYQAAQQDSGVPVREDWQTLVAHN
DKVMLEGVSLNAKGISLSLREGGLPIIEVRPQALPTYRVQLPDAAYSLYVQDTLEFDSDKIRLRYQSLNRPAQVRQLTLA
SGEQVVLKETPVLGTFDADAYVSQRLWATASDGTQVPISLVVKRELAGQATPLYLYGYGAYGESLDPWFSHARLSLLDRG
VAFAIAHVRGGGELGEAWYRNGKQEHKQNTFGDFIACAEHLVAQGLTSAGQLVISGGSAGGLLIGAVLNQRPELFKAAIA
EVPFVDVLNTMLDPDLPLTVTEYDEWGNPQEPEVYARIKAYAPYENVTAQAYPAMLVIAGYNDSRVQYWEAAKWVAKLRA
TKTDDNPLLLKTELGAGHGGMSGRYQGLRDVALEYAFIFKVLQIAE

Sequences:

>Translated_686_residues
MSFPNATSSAPIARKADGSDPYAWLQNRDTDEVLDYLKAENAWQEQQLAEQTGLRESLFEEIKGRILETDLSLPSPWGPY
LYYTRTTQGDEYARHYRCPRPADDSNTVDESAEELLLDPNEMADGGFFSLGAFSISPDHQRLAYSLDTSGDEVYALYVKE
LSTGQISSLPFENCDGSMTWANDSQTLFFGELDETHRPGRLHRHTLGTASAELVFDEPDGRFFLHCFRSSSERQLIILLN
SKTTSEAWVLDADHPQQAFTCLAPRSEGHEYYPDHGLLDGVWTWFIRSNQSGINFALYQAAQQDSGVPVREDWQTLVAHN
DKVMLEGVSLNAKGISLSLREGGLPIIEVRPQALPTYRVQLPDAAYSLYVQDTLEFDSDKIRLRYQSLNRPAQVRQLTLA
SGEQVVLKETPVLGTFDADAYVSQRLWATASDGTQVPISLVVKRELAGQATPLYLYGYGAYGESLDPWFSHARLSLLDRG
VAFAIAHVRGGGELGEAWYRNGKQEHKQNTFGDFIACAEHLVAQGLTSAGQLVISGGSAGGLLIGAVLNQRPELFKAAIA
EVPFVDVLNTMLDPDLPLTVTEYDEWGNPQEPEVYARIKAYAPYENVTAQAYPAMLVIAGYNDSRVQYWEAAKWVAKLRA
TKTDDNPLLLKTELGAGHGGMSGRYQGLRDVALEYAFIFKVLQIAE
>Mature_685_residues
SFPNATSSAPIARKADGSDPYAWLQNRDTDEVLDYLKAENAWQEQQLAEQTGLRESLFEEIKGRILETDLSLPSPWGPYL
YYTRTTQGDEYARHYRCPRPADDSNTVDESAEELLLDPNEMADGGFFSLGAFSISPDHQRLAYSLDTSGDEVYALYVKEL
STGQISSLPFENCDGSMTWANDSQTLFFGELDETHRPGRLHRHTLGTASAELVFDEPDGRFFLHCFRSSSERQLIILLNS
KTTSEAWVLDADHPQQAFTCLAPRSEGHEYYPDHGLLDGVWTWFIRSNQSGINFALYQAAQQDSGVPVREDWQTLVAHND
KVMLEGVSLNAKGISLSLREGGLPIIEVRPQALPTYRVQLPDAAYSLYVQDTLEFDSDKIRLRYQSLNRPAQVRQLTLAS
GEQVVLKETPVLGTFDADAYVSQRLWATASDGTQVPISLVVKRELAGQATPLYLYGYGAYGESLDPWFSHARLSLLDRGV
AFAIAHVRGGGELGEAWYRNGKQEHKQNTFGDFIACAEHLVAQGLTSAGQLVISGGSAGGLLIGAVLNQRPELFKAAIAE
VPFVDVLNTMLDPDLPLTVTEYDEWGNPQEPEVYARIKAYAPYENVTAQAYPAMLVIAGYNDSRVQYWEAAKWVAKLRAT
KTDDNPLLLKTELGAGHGGMSGRYQGLRDVALEYAFIFKVLQIAE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=721, Percent_Identity=27.7392510402219, Blast_Score=206, Evalue=6e-53,
Organism=Homo sapiens, GI284172438, Length=541, Percent_Identity=29.7597042513863, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI284172431, Length=541, Percent_Identity=29.7597042513863, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI284172420, Length=541, Percent_Identity=29.7597042513863, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI284172413, Length=541, Percent_Identity=29.7597042513863, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI70778815, Length=541, Percent_Identity=29.7597042513863, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI108860686, Length=217, Percent_Identity=41.9354838709677, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI108860692, Length=213, Percent_Identity=41.3145539906103, Blast_Score=150, Evalue=3e-36,
Organism=Escherichia coli, GI1788150, Length=672, Percent_Identity=39.8809523809524, Blast_Score=469, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24583414, Length=720, Percent_Identity=25.5555555555556, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI221510989, Length=685, Percent_Identity=25.6934306569343, Blast_Score=179, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 76244; Mature: 76113

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPNATSSAPIARKADGSDPYAWLQNRDTDEVLDYLKAENAWQEQQLAEQTGLRESLFE
CCCCCCCCCCCCEECCCCCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHH
EIKGRILETDLSLPSPWGPYLYYTRTTQGDEYARHYRCPRPADDSNTVDESAEELLLDPN
HHCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCH
EMADGGFFSLGAFSISPDHQRLAYSLDTSGDEVYALYVKELSTGQISSLPFENCDGSMTW
HHCCCCEEEEEEEEECCCHHEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEE
ANDSQTLFFGELDETHRPGRLHRHTLGTASAELVFDEPDGRFFLHCFRSSSERQLIILLN
CCCCCEEEEECCCCCCCCCCHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEEEE
SKTTSEAWVLDADHPQQAFTCLAPRSEGHEYYPDHGLLDGVWTWFIRSNQSGINFALYQA
CCCCCCEEEEECCCCHHHEEEECCCCCCCCCCCCCCCHHHEEEEEEECCCCCCEEEEEEH
AQQDSGVPVREDWQTLVAHNDKVMLEGVSLNAKGISLSLREGGLPIIEVRPQALPTYRVQ
HHCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCCCCCEEEECCCCCCEEEEE
LPDAAYSLYVQDTLEFDSDKIRLRYQSLNRPAQVRQLTLASGEQVVLKETPVLGTFDADA
CCCCEEEEEEEEECCCCCCEEEEEEECCCCCHHHHEEEECCCCEEEEECCCEEEECCCHH
YVSQRLWATASDGTQVPISLVVKRELAGQATPLYLYGYGAYGESLDPWFSHARLSLLDRG
HHHHHHEEECCCCCCCCHHEEEEHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
VAFAIAHVRGGGELGEAWYRNGKQEHKQNTFGDFIACAEHLVAQGLTSAGQLVISGGSAG
CEEEEEEECCCCHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
GLLIGAVLNQRPELFKAAIAEVPFVDVLNTMLDPDLPLTVTEYDEWGNPQEPEVYARIKA
CHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEE
YAPYENVTAQAYPAMLVIAGYNDSRVQYWEAAKWVAKLRATKTDDNPLLLKTELGAGHGG
ECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
MSGRYQGLRDVALEYAFIFKVLQIAE
CCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFPNATSSAPIARKADGSDPYAWLQNRDTDEVLDYLKAENAWQEQQLAEQTGLRESLFE
CCCCCCCCCCCEECCCCCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHH
EIKGRILETDLSLPSPWGPYLYYTRTTQGDEYARHYRCPRPADDSNTVDESAEELLLDPN
HHCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCH
EMADGGFFSLGAFSISPDHQRLAYSLDTSGDEVYALYVKELSTGQISSLPFENCDGSMTW
HHCCCCEEEEEEEEECCCHHEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEE
ANDSQTLFFGELDETHRPGRLHRHTLGTASAELVFDEPDGRFFLHCFRSSSERQLIILLN
CCCCCEEEEECCCCCCCCCCHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEEEE
SKTTSEAWVLDADHPQQAFTCLAPRSEGHEYYPDHGLLDGVWTWFIRSNQSGINFALYQA
CCCCCCEEEEECCCCHHHEEEECCCCCCCCCCCCCCCHHHEEEEEEECCCCCCEEEEEEH
AQQDSGVPVREDWQTLVAHNDKVMLEGVSLNAKGISLSLREGGLPIIEVRPQALPTYRVQ
HHCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCCCCCEEEECCCCCCEEEEE
LPDAAYSLYVQDTLEFDSDKIRLRYQSLNRPAQVRQLTLASGEQVVLKETPVLGTFDADA
CCCCEEEEEEEEECCCCCCEEEEEEECCCCCHHHHEEEECCCCEEEEECCCEEEECCCHH
YVSQRLWATASDGTQVPISLVVKRELAGQATPLYLYGYGAYGESLDPWFSHARLSLLDRG
HHHHHHEEECCCCCCCCHHEEEEHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
VAFAIAHVRGGGELGEAWYRNGKQEHKQNTFGDFIACAEHLVAQGLTSAGQLVISGGSAG
CEEEEEEECCCCHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
GLLIGAVLNQRPELFKAAIAEVPFVDVLNTMLDPDLPLTVTEYDEWGNPQEPEVYARIKA
CHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEE
YAPYENVTAQAYPAMLVIAGYNDSRVQYWEAAKWVAKLRATKTDDNPLLLKTELGAGHGG
ECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
MSGRYQGLRDVALEYAFIFKVLQIAE
CCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]