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The map label for this gene is yafC [H]

Identifier: 66044685

GI number: 66044685

Start: 1626243

End: 1627124

Strand: Direct

Name: yafC [H]

Synonym: Psyr_1437

Alternate gene names: 66044685

Gene position: 1626243-1627124 (Clockwise)

Preceding gene: 66044684

Following gene: 66044686

Centisome position: 26.69

GC content: 52.95

Gene sequence:

>882_bases
ATGGATATTCAAGCGCTGAACCTGTTTGTCAGATCCATGGAAATGGGAAACATCACCGCTGCTGGGGCGGAGTTAGGGCT
GGTGCCTTCGGTAGCGAGTCAAAAACTCGCCAAGCTCGAGAAGTCATTGGGCATGCGGTTGCTGCATCGCACGACAAGGC
AGGTGACCCTTACAGAGGACGGTGCGCTTTTCCTGCCTCATGCTTCTCGTATCATAGCCGCTGTGGACGAAGCTTATTTT
ACGACTGTGAAGAGCCAGGAGACGCCTAAACGCGTATTGCGTATCTCAGCCCCCGGCTCTTTCGCCAGGGTCTGTTTGAT
GCCTGCGGTGACTCGCTTTCTACGAAGCCATCCCAATCTGAAAATAGACCTGGTGCTTTCGGATGAAGTGCAAAACTTAA
CGGAGATCGGCATTGATGTGGCCATTCGCATCGCCGCACTGAAGGACTCAACACATGTGGCGCGCAAGCTTGGAAACGAC
ACCCGTATTCTTTGCGCGTCCCCGGCCTACCTTGAACAAAAAGGTAAGCCGGGAGAGCCCGAAGATTTGAGCCGCCACGA
TTGCATTACATTGGGAGAAGAGAATCGCTGGCACTTCGCGGGTAACGCACGCAATCCATTTTCTATAATTAACGGCTCTT
TTAGAGTCAACTGCGGGGAAGCTGCTCGAATAGCGGCTGTAGAAGGGCTGGGGATCGCTTCCATATCGCTATGGAATGCC
CGAGCGTCCTTGAGTAAAGGGGATCTGGTCGAAGTCCTTTCCTCTTTTGCTCTCGAACAAAGCCGCGCTGTCTGGGCTAT
TTATCCCAGCTCCCGGCAAATCTCCTCCAAAGCACGCGCGTTTGTCGATTTCCTCAGCCAAGAATTTGTTGACGGATTCT
GA

Upstream 100 bases:

>100_bases
GGGATTTCATGGTGGCAAAGATTTACGAGAAAAACCCTACAGTTTGATGCGAGTGAAGATCAACGCAACACCGGTGCAGA
CACGCTGAACGGGGCCAGCC

Downstream 100 bases:

>100_bases
GCGGATCATGACCGCCGAGCAGCTATACCCCAGAATTGACTACTGCTCAAGGTGCGTCATTTAAGTCCCCGCTTATGCGG
CAGCAAGTGATCGATCTCAC

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDIQALNLFVRSMEMGNITAAGAELGLVPSVASQKLAKLEKSLGMRLLHRTTRQVTLTEDGALFLPHASRIIAAVDEAYF
TTVKSQETPKRVLRISAPGSFARVCLMPAVTRFLRSHPNLKIDLVLSDEVQNLTEIGIDVAIRIAALKDSTHVARKLGND
TRILCASPAYLEQKGKPGEPEDLSRHDCITLGEENRWHFAGNARNPFSIINGSFRVNCGEAARIAAVEGLGIASISLWNA
RASLSKGDLVEVLSSFALEQSRAVWAIYPSSRQISSKARAFVDFLSQEFVDGF

Sequences:

>Translated_293_residues
MDIQALNLFVRSMEMGNITAAGAELGLVPSVASQKLAKLEKSLGMRLLHRTTRQVTLTEDGALFLPHASRIIAAVDEAYF
TTVKSQETPKRVLRISAPGSFARVCLMPAVTRFLRSHPNLKIDLVLSDEVQNLTEIGIDVAIRIAALKDSTHVARKLGND
TRILCASPAYLEQKGKPGEPEDLSRHDCITLGEENRWHFAGNARNPFSIINGSFRVNCGEAARIAAVEGLGIASISLWNA
RASLSKGDLVEVLSSFALEQSRAVWAIYPSSRQISSKARAFVDFLSQEFVDGF
>Mature_293_residues
MDIQALNLFVRSMEMGNITAAGAELGLVPSVASQKLAKLEKSLGMRLLHRTTRQVTLTEDGALFLPHASRIIAAVDEAYF
TTVKSQETPKRVLRISAPGSFARVCLMPAVTRFLRSHPNLKIDLVLSDEVQNLTEIGIDVAIRIAALKDSTHVARKLGND
TRILCASPAYLEQKGKPGEPEDLSRHDCITLGEENRWHFAGNARNPFSIINGSFRVNCGEAARIAAVEGLGIASISLWNA
RASLSKGDLVEVLSSFALEQSRAVWAIYPSSRQISSKARAFVDFLSQEFVDGF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=34.4947735191638, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=32.9824561403509, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=33.1058020477816, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=30.5647840531561, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=29.4520547945205, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787128, Length=274, Percent_Identity=29.1970802919708, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=27.9310344827586, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786448, Length=279, Percent_Identity=27.5985663082437, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788706, Length=288, Percent_Identity=25, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=24, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32005; Mature: 32005

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQALNLFVRSMEMGNITAAGAELGLVPSVASQKLAKLEKSLGMRLLHRTTRQVTLTED
CCHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECC
GALFLPHASRIIAAVDEAYFTTVKSQETPKRVLRISAPGSFARVCLMPAVTRFLRSHPNL
CEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCE
KIDLVLSDEVQNLTEIGIDVAIRIAALKDSTHVARKLGNDTRILCASPAYLEQKGKPGEP
EEEEEECHHHHHHHHHCCEEEEEEEEECCHHHHHHHCCCCCEEEEECCHHHHCCCCCCCC
EDLSRHDCITLGEENRWHFAGNARNPFSIINGSFRVNCGEAARIAAVEGLGIASISLWNA
CCCCCCCEEEECCCCCEEEECCCCCCCEEECCEEEEECCCCCEEEEECCCCEEEEEEECC
RASLSKGDLVEVLSSFALEQSRAVWAIYPSSRQISSKARAFVDFLSQEFVDGF
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIQALNLFVRSMEMGNITAAGAELGLVPSVASQKLAKLEKSLGMRLLHRTTRQVTLTED
CCHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECC
GALFLPHASRIIAAVDEAYFTTVKSQETPKRVLRISAPGSFARVCLMPAVTRFLRSHPNL
CEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCE
KIDLVLSDEVQNLTEIGIDVAIRIAALKDSTHVARKLGNDTRILCASPAYLEQKGKPGEP
EEEEEECHHHHHHHHHCCEEEEEEEEECCHHHHHHHCCCCCEEEEECCHHHHCCCCCCCC
EDLSRHDCITLGEENRWHFAGNARNPFSIINGSFRVNCGEAARIAAVEGLGIASISLWNA
CCCCCCCEEEECCCCCEEEECCCCCCCEEECCEEEEECCCCCEEEEECCCCEEEEEEECC
RASLSKGDLVEVLSSFALEQSRAVWAIYPSSRQISSKARAFVDFLSQEFVDGF
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]