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The map label for this gene is cyoB [H]

Identifier: 66044393

GI number: 66044393

Start: 1293302

End: 1295314

Strand: Direct

Name: cyoB [H]

Synonym: Psyr_1142

Alternate gene names: 66044393

Gene position: 1293302-1295314 (Clockwise)

Preceding gene: 66044392

Following gene: 66044394

Centisome position: 21.22

GC content: 57.72

Gene sequence:

>2013_bases
ATGTTTGGCAAATTAAGTCTGGAAGCGGTGCCGTTCCACGAGCCCATAGTCATGGTGACACTTGCCATGATCGCGCTCGG
CGGCATTGCGGTTGTCGGGTTGATCACCTATTTCCGCAAGTGGACGTACTTGTGGTCTGAGTGGCTGACCTCTGTCGACC
ACAAGAAAATCGGCGTGATGTACATCGTCGTTGCCATGGTCATGCTGCTGCGCGGTTTTGCCGACGCGATCATGATGCGT
ACCCAACTGGCGATGGCCCAGAACGGTTCCGAAGGGTTCCTTCCGCCTGAACACTATGACCAGATCTTCACCGCTCACGG
TGTGATCATGATCATCTTCATGGCGATGCCGTTCTTCACGGGTCTGATGAACATCGTTCTGCCTCTGCAGATCGGCGCTC
GCGACGTGGCGTTCCCGTTCCTGAACTCCCTGAGCTTCTGGCTGCTGGTCGCAGGTATGCTGCTGATCAACATCTCCCTG
GGTGTCGGTGAGTTCGCCAAGACCGGCTGGGTCGCGTATCCGCCTCTTTCCGGGTTGCAATACAGTCCTGGCGTAGGGGT
TGACTACTACATCTGGGCGCTACAGTTATCCGGCTTGGGTACGACGCTGACGGGGGTCAACTTCCTCGTGACCGTGCTGA
AGATGCGTACCCCTGGCATGAAACTGATGGACATGCCGATCTTCACCTGGACCTGCACCTGGGCAAACATCCTGATCGTG
GCTTCGTTCCCGATCCTGACCGCTACCCTGGCGTTCCTGACCCTTGACCGCTACCTGGACTTCCACATTTTCACGAACGA
AATGGGCGGTAACCCCATGATGTACGTGAACCTGTTCTGGGCGTGGGGTCACCCTGAGGTGTACATCCTGATCCTGCCGG
CCTTCGGCGTGTTCTCGGAAGTCATCTCGACGTTCTCCGGCAAGCGTCTGTTCGGCCACAAGTCGATGATCTTCGCCTCC
GGTGCGATCTGTATCCTGGGCTTCATGGTCTGGCTGCACCACTTCTTCACCATGGGGGCGGGTGCCAACGTCAACGCCTT
CTTCGGTCTGGCGACGATGCTGATTGCGATCCCGACGGGTGTGAAGCTGTTCAACTGGCTGTTCACCATGTATCAGGGCC
GTCTGCGCTTCACTGCGCCGGTGCTCTGGACCCTGGGCTTCATGGTCACCTTCTCGATCGGCGGCATGACCGGCGTTCTG
TTGGCGATCCCGGGTGCTGACTTCGTGCTGCACAACAGCCTGTTCGTAATCGCTCACTTCCACAACGTCATCATCGGCGG
TGCGGTATTCGGTTACATCGCCGGCTTCGCGTTCTGGTTCCCTAAAGCGTTCGGTTTCACCCTGAACGAGAAGTGGGGCA
AGGCAGCGTTCTGGTTCTGGATCGTCGGCTTCTTCGTCGCATTCATGCCGCTTTACGCGCTGGGCTTCCTGGGCATGACC
CGTCGTCTGAACGCTACCGACATGCCAGAGTGGAACATCTACCTGGACGTCGCGCTGTTCGGCGCCGTGCTGATTGCCAT
GGGTATCGCTTCGCAGCTGATCCAGCTGTTCGTGAGTATCCGTGACCGCGACAACAACCGCGATCTGACCGGTGACCCAT
GGAATGGCCATACCCTGGAATGGTCCACTTCTTCGCCTCCACCGTTCTACAACTTTGCCGAGCTGCCAAAAGCTGACGAC
ATCGATCCGTTCACCGATGCGAAACGTGCCGGTACCGCTTACAAGGTTCCTGCCCGCTACTCGGCGATCCACATGCCTAA
CAACACGGCTACCGGCCTGTACATGGGTATGTTGCTGACGGTCTTCGGCTTCGCATTCATCTGGCACATCTGGTGGCTGG
TAGGCGCAAGCCTGGTCGCGACCATTGCAGTCTTCGTTGCTCACGCTGTCCGTGACGACCAGGGCTACATGGTGCCTGCT
GAAGATGTAGCGCGTATTGAAGGTGAGCATCACAAGGTCCTGGCGGCCAACGGTGCATACACTCCTGTCAAGTCCTCGCT
GGAACAGGTTTAA

Upstream 100 bases:

>100_bases
GAATCCGGGCAAGAAGGTTGTTGCTGGTGAGAAGGAAGTAGCCGGTGAGGCTGGTGCGGAAAAAGGCAAAAATTCAGCTG
CTGGGGCAGAGGAGTAAACG

Downstream 100 bases:

>100_bases
ACAATGTCAAATATTGCAATCAACTCCGGAGCCCACGATCACGGTCACGACCATGATCATGGGCATGACGATCACCACGA
CAGCGGTGGCATGACGGTCT

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MFGKLSLEAVPFHEPIVMVTLAMIALGGIAVVGLITYFRKWTYLWSEWLTSVDHKKIGVMYIVVAMVMLLRGFADAIMMR
TQLAMAQNGSEGFLPPEHYDQIFTAHGVIMIIFMAMPFFTGLMNIVLPLQIGARDVAFPFLNSLSFWLLVAGMLLINISL
GVGEFAKTGWVAYPPLSGLQYSPGVGVDYYIWALQLSGLGTTLTGVNFLVTVLKMRTPGMKLMDMPIFTWTCTWANILIV
ASFPILTATLAFLTLDRYLDFHIFTNEMGGNPMMYVNLFWAWGHPEVYILILPAFGVFSEVISTFSGKRLFGHKSMIFAS
GAICILGFMVWLHHFFTMGAGANVNAFFGLATMLIAIPTGVKLFNWLFTMYQGRLRFTAPVLWTLGFMVTFSIGGMTGVL
LAIPGADFVLHNSLFVIAHFHNVIIGGAVFGYIAGFAFWFPKAFGFTLNEKWGKAAFWFWIVGFFVAFMPLYALGFLGMT
RRLNATDMPEWNIYLDVALFGAVLIAMGIASQLIQLFVSIRDRDNNRDLTGDPWNGHTLEWSTSSPPPFYNFAELPKADD
IDPFTDAKRAGTAYKVPARYSAIHMPNNTATGLYMGMLLTVFGFAFIWHIWWLVGASLVATIAVFVAHAVRDDQGYMVPA
EDVARIEGEHHKVLAANGAYTPVKSSLEQV

Sequences:

>Translated_670_residues
MFGKLSLEAVPFHEPIVMVTLAMIALGGIAVVGLITYFRKWTYLWSEWLTSVDHKKIGVMYIVVAMVMLLRGFADAIMMR
TQLAMAQNGSEGFLPPEHYDQIFTAHGVIMIIFMAMPFFTGLMNIVLPLQIGARDVAFPFLNSLSFWLLVAGMLLINISL
GVGEFAKTGWVAYPPLSGLQYSPGVGVDYYIWALQLSGLGTTLTGVNFLVTVLKMRTPGMKLMDMPIFTWTCTWANILIV
ASFPILTATLAFLTLDRYLDFHIFTNEMGGNPMMYVNLFWAWGHPEVYILILPAFGVFSEVISTFSGKRLFGHKSMIFAS
GAICILGFMVWLHHFFTMGAGANVNAFFGLATMLIAIPTGVKLFNWLFTMYQGRLRFTAPVLWTLGFMVTFSIGGMTGVL
LAIPGADFVLHNSLFVIAHFHNVIIGGAVFGYIAGFAFWFPKAFGFTLNEKWGKAAFWFWIVGFFVAFMPLYALGFLGMT
RRLNATDMPEWNIYLDVALFGAVLIAMGIASQLIQLFVSIRDRDNNRDLTGDPWNGHTLEWSTSSPPPFYNFAELPKADD
IDPFTDAKRAGTAYKVPARYSAIHMPNNTATGLYMGMLLTVFGFAFIWHIWWLVGASLVATIAVFVAHAVRDDQGYMVPA
EDVARIEGEHHKVLAANGAYTPVKSSLEQV
>Mature_670_residues
MFGKLSLEAVPFHEPIVMVTLAMIALGGIAVVGLITYFRKWTYLWSEWLTSVDHKKIGVMYIVVAMVMLLRGFADAIMMR
TQLAMAQNGSEGFLPPEHYDQIFTAHGVIMIIFMAMPFFTGLMNIVLPLQIGARDVAFPFLNSLSFWLLVAGMLLINISL
GVGEFAKTGWVAYPPLSGLQYSPGVGVDYYIWALQLSGLGTTLTGVNFLVTVLKMRTPGMKLMDMPIFTWTCTWANILIV
ASFPILTATLAFLTLDRYLDFHIFTNEMGGNPMMYVNLFWAWGHPEVYILILPAFGVFSEVISTFSGKRLFGHKSMIFAS
GAICILGFMVWLHHFFTMGAGANVNAFFGLATMLIAIPTGVKLFNWLFTMYQGRLRFTAPVLWTLGFMVTFSIGGMTGVL
LAIPGADFVLHNSLFVIAHFHNVIIGGAVFGYIAGFAFWFPKAFGFTLNEKWGKAAFWFWIVGFFVAFMPLYALGFLGMT
RRLNATDMPEWNIYLDVALFGAVLIAMGIASQLIQLFVSIRDRDNNRDLTGDPWNGHTLEWSTSSPPPFYNFAELPKADD
IDPFTDAKRAGTAYKVPARYSAIHMPNNTATGLYMGMLLTVFGFAFIWHIWWLVGASLVATIAVFVAHAVRDDQGYMVPA
EDVARIEGEHHKVLAANGAYTPVKSSLEQV

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=516, Percent_Identity=39.922480620155, Blast_Score=339, Evalue=5e-93,
Organism=Escherichia coli, GI1786634, Length=658, Percent_Identity=68.8449848024316, Blast_Score=955, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=528, Percent_Identity=37.6893939393939, Blast_Score=341, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=42.2839506172839, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=35.7429718875502, Blast_Score=133, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74513; Mature: 74513

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLSLEAVPFHEPIVMVTLAMIALGGIAVVGLITYFRKWTYLWSEWLTSVDHKKIGVM
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YIVVAMVMLLRGFADAIMMRTQLAMAQNGSEGFLPPEHYDQIFTAHGVIMIIFMAMPFFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLMNIVLPLQIGARDVAFPFLNSLSFWLLVAGMLLINISLGVGEFAKTGWVAYPPLSGLQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEECCCCCCCC
YSPGVGVDYYIWALQLSGLGTTLTGVNFLVTVLKMRTPGMKLMDMPIFTWTCTWANILIV
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEEEEHHHHHHHHH
ASFPILTATLAFLTLDRYLDFHIFTNEMGGNPMMYVNLFWAWGHPEVYILILPAFGVFSE
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEEEEECCCEEEEEEECCHHHHHH
VISTFSGKRLFGHKSMIFASGAICILGFMVWLHHFFTMGAGANVNAFFGLATMLIAIPTG
HHHHCCCCEEECCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCH
VKLFNWLFTMYQGRLRFTAPVLWTLGFMVTFSIGGMTGVLLAIPGADFVLHNSLFVIAHF
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHCCEEEEEHH
HNVIIGGAVFGYIAGFAFWFPKAFGFTLNEKWGKAAFWFWIVGFFVAFMPLYALGFLGMT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLNATDMPEWNIYLDVALFGAVLIAMGIASQLIQLFVSIRDRDNNRDLTGDPWNGHTLE
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
WSTSSPPPFYNFAELPKADDIDPFTDAKRAGTAYKVPARYSAIHMPNNTATGLYMGMLLT
ECCCCCCCCCCHHCCCCCCCCCCCCCHHHCCCEEECCCCEEEEECCCCCCHHHHHHHHHH
VFGFAFIWHIWWLVGASLVATIAVFVAHAVRDDQGYMVPAEDVARIEGEHHKVLAANGAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHCCCCCEEEEECCCC
TPVKSSLEQV
CHHHHHHHCC
>Mature Secondary Structure
MFGKLSLEAVPFHEPIVMVTLAMIALGGIAVVGLITYFRKWTYLWSEWLTSVDHKKIGVM
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YIVVAMVMLLRGFADAIMMRTQLAMAQNGSEGFLPPEHYDQIFTAHGVIMIIFMAMPFFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLMNIVLPLQIGARDVAFPFLNSLSFWLLVAGMLLINISLGVGEFAKTGWVAYPPLSGLQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEECCCCCCCC
YSPGVGVDYYIWALQLSGLGTTLTGVNFLVTVLKMRTPGMKLMDMPIFTWTCTWANILIV
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEEEEHHHHHHHHH
ASFPILTATLAFLTLDRYLDFHIFTNEMGGNPMMYVNLFWAWGHPEVYILILPAFGVFSE
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEEEEECCCEEEEEEECCHHHHHH
VISTFSGKRLFGHKSMIFASGAICILGFMVWLHHFFTMGAGANVNAFFGLATMLIAIPTG
HHHHCCCCEEECCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCH
VKLFNWLFTMYQGRLRFTAPVLWTLGFMVTFSIGGMTGVLLAIPGADFVLHNSLFVIAHF
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHCCEEEEEHH
HNVIIGGAVFGYIAGFAFWFPKAFGFTLNEKWGKAAFWFWIVGFFVAFMPLYALGFLGMT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLNATDMPEWNIYLDVALFGAVLIAMGIASQLIQLFVSIRDRDNNRDLTGDPWNGHTLE
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
WSTSSPPPFYNFAELPKADDIDPFTDAKRAGTAYKVPARYSAIHMPNNTATGLYMGMLLT
ECCCCCCCCCCHHCCCCCCCCCCCCCHHHCCCEEECCCCEEEEECCCCCCHHHHHHHHHH
VFGFAFIWHIWWLVGASLVATIAVFVAHAVRDDQGYMVPAEDVARIEGEHHKVLAANGAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHCCCCCEEEEECCCC
TPVKSSLEQV
CHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9868765 [H]