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The map label for this gene is eda [H]

Identifier: 66044373

GI number: 66044373

Start: 1271448

End: 1272122

Strand: Direct

Name: eda [H]

Synonym: Psyr_1122

Alternate gene names: 66044373

Gene position: 1271448-1272122 (Clockwise)

Preceding gene: 66044372

Following gene: 66044375

Centisome position: 20.86

GC content: 62.52

Gene sequence:

>675_bases
ATGACACAGAACGAAAATAATCAGCCGCTGACCAGCATGGCGAACAAGATTGCCCAGATCGACGAACTCTGCGCCAAGGC
GAAGATTCTGCCGGTGATCACCATCGCCCGTGACCAGGACGTACTGCCGCTGGCCGATGCACTGGCCGCTGGCGGCATGA
CTGCGCTGGAAGTGACCCTGCGCTCGGCGTTCGGCCTGAGCGCCATTCGTATCCTGCGTGAACAGCGCCCCGAGTTGTGT
GTGGGCGCGGGGACGATCCTGGACCGCAAGATGCTGGCCGACGCCGAAGCGGCCGGTTCGCAGTTCATCGTGACGCCCGG
CAGCACGCAGGAACTCTTGCAGGCGGCGCTCGACAGCCCGCTGCCTTTGCTACCCGGCATCAGCAGTGCCTCGGAAATCA
TGATCGGCTACGCCATGGGCTATCGCCGTTTCAAGCTGTTTCCGGCCGAGATCAGCGGCGGTGTGGCAGCGATCAAAGCC
CTTGGCGGGCCGTTCAACGAGGTGCGTTTCTGCCCCACTGGCGGCGTTAATGAGCAGAACCTCAAGAGCTACATGGCCCT
GCCCAACGTCATGTGCGTGGGCGGCACCTGGATGATCGATAACGCCTGGGTCAAGAATGGCGACTGGGGGCGTATCCAGG
AAGCGACTGCGCAGGCCATGGCGCTGTTTGACTGA

Upstream 100 bases:

>100_bases
CCTCGCCGAAATGCCGGTGCGTGCCTTTCTCAACCCGTCTCTCGAGATTTACTGGTGCCCATAAGCCCCGATAAGCCCCA
CAAACAAAGGAACCGTCGCC

Downstream 100 bases:

>100_bases
TTTTCAGGATTTCGGCGTCAGCCCCTTGCGGCTGATTCCGACAAGGAAGTTGTTGTTGGTTGTATGGCTTTTCGGTGCTC
CCTGGTCCGGAGCACCGTTT

Product: keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase

Products: NA

Alternate protein names: KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTQNENNQPLTSMANKIAQIDELCAKAKILPVITIARDQDVLPLADALAAGGMTALEVTLRSAFGLSAIRILREQRPELC
VGAGTILDRKMLADAEAAGSQFIVTPGSTQELLQAALDSPLPLLPGISSASEIMIGYAMGYRRFKLFPAEISGGVAAIKA
LGGPFNEVRFCPTGGVNEQNLKSYMALPNVMCVGGTWMIDNAWVKNGDWGRIQEATAQAMALFD

Sequences:

>Translated_224_residues
MTQNENNQPLTSMANKIAQIDELCAKAKILPVITIARDQDVLPLADALAAGGMTALEVTLRSAFGLSAIRILREQRPELC
VGAGTILDRKMLADAEAAGSQFIVTPGSTQELLQAALDSPLPLLPGISSASEIMIGYAMGYRRFKLFPAEISGGVAAIKA
LGGPFNEVRFCPTGGVNEQNLKSYMALPNVMCVGGTWMIDNAWVKNGDWGRIQEATAQAMALFD
>Mature_223_residues
TQNENNQPLTSMANKIAQIDELCAKAKILPVITIARDQDVLPLADALAAGGMTALEVTLRSAFGLSAIRILREQRPELCV
GAGTILDRKMLADAEAAGSQFIVTPGSTQELLQAALDSPLPLLPGISSASEIMIGYAMGYRRFKLFPAEISGGVAAIKAL
GGPFNEVRFCPTGGVNEQNLKSYMALPNVMCVGGTWMIDNAWVKNGDWGRIQEATAQAMALFD

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=182, Percent_Identity=46.1538461538462, Blast_Score=186, Evalue=8e-49,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.14 [H]

Molecular weight: Translated: 23856; Mature: 23725

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1 ; PS00160 ALDOLASE_KDPG_KHG_2 ; PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNENNQPLTSMANKIAQIDELCAKAKILPVITIARDQDVLPLADALAAGGMTALEVTL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHH
RSAFGLSAIRILREQRPELCVGAGTILDRKMLADAEAAGSQFIVTPGSTQELLQAALDSP
HHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCC
LPLLPGISSASEIMIGYAMGYRRFKLFPAEISGGVAAIKALGGPFNEVRFCPTGGVNEQN
CCCCCCCCCHHHHHHHHHHCCEEEEEEHHHHCCHHHHHHHHCCCHHHEEECCCCCCCHHH
LKSYMALPNVMCVGGTWMIDNAWVKNGDWGRIQEATAQAMALFD
HHHHHHCCCEEEECCEEEECCCEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQNENNQPLTSMANKIAQIDELCAKAKILPVITIARDQDVLPLADALAAGGMTALEVTL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHH
RSAFGLSAIRILREQRPELCVGAGTILDRKMLADAEAAGSQFIVTPGSTQELLQAALDSP
HHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCC
LPLLPGISSASEIMIGYAMGYRRFKLFPAEISGGVAAIKALGGPFNEVRFCPTGGVNEQN
CCCCCCCCCHHHHHHHHHHCCEEEEEEHHHHCCHHHHHHHHCCCHHHEEECCCCCCCHHH
LKSYMALPNVMCVGGTWMIDNAWVKNGDWGRIQEATAQAMALFD
HHHHHHCCCEEEECCEEEECCCEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6988426; 7161801; 974067 [H]