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The map label for this gene is pgl [H]

Identifier: 66044372

GI number: 66044372

Start: 1270698

End: 1271411

Strand: Direct

Name: pgl [H]

Synonym: Psyr_1121

Alternate gene names: 66044372

Gene position: 1270698-1271411 (Clockwise)

Preceding gene: 66044371

Following gene: 66044373

Centisome position: 20.85

GC content: 65.13

Gene sequence:

>714_bases
ATGGCGACATGTGACCTCAAGCTGCCAGCAGGGCTGGTAGCACACGATTTCGACACGGCGCAGCAACTGGCCGATGCACT
GGCCGAAAAGGTCGCCGAGCGCCTGAAGCAGGCGATCAGCGAGAACGGTCTGGCGACGCTGGTGGTGTCCGGTGGACGCA
GCCCGGTCGCCTTCTTCCAGAGTCTGGCGACACAACCGCTGGAGTGGTCGAAGGTCGTCATCAGTCTGGCGGACGAGCGC
TTCGTGCCGACCGAACATGCCGACAGCAATGCCGGCCTGCTGCAGCGCCACTTGCTGCAGGGGCCTGTGGCGAAGGCCAG
GTTTCTCGGCCTGTACAGCGTTGCGAGCAGTGTCGAGGAAGCCGCGCAGGCTGCCGATCAGGCCTTGGCCGAGCTGCCAC
CCATAGATGTACTGATTCTGGGCATGGGCGACGACGGGCATACCGCATCGCTATTCCCCAACAGCCCGAATCTGAGCGAA
GCCCTTGATCTGCAAGGCGAGCGCCGCTGCCTGCCCATGCTCGCACCGAGCGTGCCGCACCAGCGCCTGACCCTGACCCG
CCGCCTGCTGGCGTCGGCGCGCTCACCGATTCTGTCGGTGTCCGGTCAGGCCAAGCTCGACACCCTGCGCGCCGCGCTGG
CAGGCGATGACCTCGCCGAAATGCCGGTGCGTGCCTTTCTCAACCCGTCTCTCGAGATTTACTGGTGCCCATAA

Upstream 100 bases:

>100_bases
GGCTGGAAGAAGGCGGGCGATGCGCCCAAGCCTTACCCGGCCGGAACCTGGGGGCCGATGAGCTCCATTGCCCTGATTAC
TCGCGACGGGAGATCCTGGT

Downstream 100 bases:

>100_bases
GCCCCGATAAGCCCCACAAACAAAGGAACCGTCGCCATGACACAGAACGAAAATAATCAGCCGCTGACCAGCATGGCGAA
CAAGATTGCCCAGATCGACG

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MATCDLKLPAGLVAHDFDTAQQLADALAEKVAERLKQAISENGLATLVVSGGRSPVAFFQSLATQPLEWSKVVISLADER
FVPTEHADSNAGLLQRHLLQGPVAKARFLGLYSVASSVEEAAQAADQALAELPPIDVLILGMGDDGHTASLFPNSPNLSE
ALDLQGERRCLPMLAPSVPHQRLTLTRRLLASARSPILSVSGQAKLDTLRAALAGDDLAEMPVRAFLNPSLEIYWCP

Sequences:

>Translated_237_residues
MATCDLKLPAGLVAHDFDTAQQLADALAEKVAERLKQAISENGLATLVVSGGRSPVAFFQSLATQPLEWSKVVISLADER
FVPTEHADSNAGLLQRHLLQGPVAKARFLGLYSVASSVEEAAQAADQALAELPPIDVLILGMGDDGHTASLFPNSPNLSE
ALDLQGERRCLPMLAPSVPHQRLTLTRRLLASARSPILSVSGQAKLDTLRAALAGDDLAEMPVRAFLNPSLEIYWCP
>Mature_236_residues
ATCDLKLPAGLVAHDFDTAQQLADALAEKVAERLKQAISENGLATLVVSGGRSPVAFFQSLATQPLEWSKVVISLADERF
VPTEHADSNAGLLQRHLLQGPVAKARFLGLYSVASSVEEAAQAADQALAELPPIDVLILGMGDDGHTASLFPNSPNLSEA
LDLQGERRCLPMLAPSVPHQRLTLTRRLLASARSPILSVSGQAKLDTLRAALAGDDLAEMPVRAFLNPSLEIYWCP

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=228, Percent_Identity=32.8947368421053, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI6912586, Length=224, Percent_Identity=32.5892857142857, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115533058, Length=205, Percent_Identity=27.8048780487805, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115533060, Length=205, Percent_Identity=27.8048780487805, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321687, Length=209, Percent_Identity=29.1866028708134, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321957, Length=204, Percent_Identity=27.9411764705882, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641119, Length=216, Percent_Identity=28.2407407407407, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25278; Mature: 25147

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATCDLKLPAGLVAHDFDTAQQLADALAEKVAERLKQAISENGLATLVVSGGRSPVAFFQ
CCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
SLATQPLEWSKVVISLADERFVPTEHADSNAGLLQRHLLQGPVAKARFLGLYSVASSVEE
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AAQAADQALAELPPIDVLILGMGDDGHTASLFPNSPNLSEALDLQGERRCLPMLAPSVPH
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCHHHHHCCCCCCCCHHHHCCCCCH
QRLTLTRRLLASARSPILSVSGQAKLDTLRAALAGDDLAEMPVRAFLNPSLEIYWCP
HHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure 
ATCDLKLPAGLVAHDFDTAQQLADALAEKVAERLKQAISENGLATLVVSGGRSPVAFFQ
CCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
SLATQPLEWSKVVISLADERFVPTEHADSNAGLLQRHLLQGPVAKARFLGLYSVASSVEE
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AAQAADQALAELPPIDVLILGMGDDGHTASLFPNSPNLSEALDLQGERRCLPMLAPSVPH
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCHHHHHCCCCCCCCHHHHCCCCCH
QRLTLTRRLLASARSPILSVSGQAKLDTLRAALAGDDLAEMPVRAFLNPSLEIYWCP
HHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA