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The map label for this gene is fabG [H]

Identifier: 66043911

GI number: 66043911

Start: 731340

End: 732695

Strand: Reverse

Name: fabG [H]

Synonym: Psyr_0644

Alternate gene names: 66043911

Gene position: 732695-731340 (Counterclockwise)

Preceding gene: 66043915

Following gene: 66043910

Centisome position: 12.02

GC content: 64.38

Gene sequence:

>1356_bases
ATGCCGTCAGATCGCTATATTGATTTCGCCAACTCCGACATGGGTCGGCGCCTGGTGAAGGCCGTCGGTCTGCCCGCCCC
CACTCACCTGGAGCGCTGGCAGGCCGGACGTCTGCGCCCCGTCGAAGGGACCTTGCTGATCAGCGCAGGACCGCTGGGCG
ATCAGGTCCGCCAGTTCGCCAGCCGTCTGACCGACTCGCTGTACAGCTTCGGCAGCGACATGCCCGGCGCCACGACGTGG
GTGTCCAACCAGGGTCCGCGCCTTAAGGCAGTGGTTTTCGACGCCAGCCAGATCCTGCGCACCGATCAGCTCAGGCAGTT
GCGGGACTTCTTTCAGCCGCTGCTGCGCAATCTCGATCACTGCGCGCATGTGGTCATTCTCGGCAAGGCACCCGAGACAC
TCACTGATCCGCTGGCGGCCAGCACTCAACAGGCCATCGAAGGCTTCAGCCGCTCGCTGGCCAAGGAAGTGCGCAATGGC
GCAACGGTCAAGTTGCTGCAGGTGGATGACGACGCGCAGGATCAACTGGAGGGCGCCCTGCGCTTCTTCCTCACGCCCAA
GGCTGCGTTCATCTCCGGCCAGTTCGTCCACCTCAGTGCCTGCCCGAGCAAGGTGCAGGACTGGACCCGCCCGCTGGCCG
GGCTCAAGGCAGTAGTGACGGGCGCTGCACGCGGCATAGGCGCGTCAATCGCCGAAACCCTGACCCGTGATGGCGCGCAG
GTCATTCTGCTGGATGTACCGCAGACCAAGAACGAGCTGGAAGCACTCGCCTCACGGCTTGGCGGTCAGGCCCTGGCGCT
GGATATCTGCGCGGCGGATGCCCCGGCGCAGTTGCTCGAACACCTGCCCGACGGCGTCGACATACTGGTGCACAACGCCG
GCATCACGCGCGACAAGACGCTGGTCAACATGCCGGAAGATTTCTGGGACTCGGTACTGGCGGTCAACCTCAGTGCGCCG
CAAGTGCTGACTCAAGTACTGCTCGACGCGGGAGCCTTGAAGGATAACGCGCGGATCGTGCTCATGGCCTCGATCAGCGG
TATCGCCGGTAACCGCGGGCAAACCAACTACACCACCAGCAAGGCAGGTCTGATCGGTTTTGCACGGGCCATGGCCCCCG
GGCTCAAGTCACGCGGCATCAGCATCAACGCCGTCGCGCCGGGCTTCATCGAAACGAAAATGACCGCGCACATGCCGTTC
ACCCTGCGTGAAGCCGGGCGGCGCATGAGTTCGCTGGGTCAGGGCGGCTCGCCACAGGACGTTGCCGAAGCGGTGGCGTG
GTTCAGCCAGCCGGGCAGCGGCGCGGTGAGCGGTCAGGTTCTACGTGTATGTGGTCAAAACGTGATCGGGGCTTAA

Upstream 100 bases:

>100_bases
CCCTTTCTTCAAGCGAATGAATGAGCCGTGTCGATCGCAAGAACAAACGTCATGCCACCGTGGTCCATTCCTTTGAACCC
CGACTTCAGGAGAGTGTTCC

Downstream 100 bases:

>100_bases
GCACCCGCATCGAATTCAAGGAGATGGATGATGACGGCTCACTGGCGCTACCTCAATTCCCTGCAGCCCCTGTCCAACCT
GTTCATCCAGGCAGCGCTCA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MPSDRYIDFANSDMGRRLVKAVGLPAPTHLERWQAGRLRPVEGTLLISAGPLGDQVRQFASRLTDSLYSFGSDMPGATTW
VSNQGPRLKAVVFDASQILRTDQLRQLRDFFQPLLRNLDHCAHVVILGKAPETLTDPLAASTQQAIEGFSRSLAKEVRNG
ATVKLLQVDDDAQDQLEGALRFFLTPKAAFISGQFVHLSACPSKVQDWTRPLAGLKAVVTGAARGIGASIAETLTRDGAQ
VILLDVPQTKNELEALASRLGGQALALDICAADAPAQLLEHLPDGVDILVHNAGITRDKTLVNMPEDFWDSVLAVNLSAP
QVLTQVLLDAGALKDNARIVLMASISGIAGNRGQTNYTTSKAGLIGFARAMAPGLKSRGISINAVAPGFIETKMTAHMPF
TLREAGRRMSSLGQGGSPQDVAEAVAWFSQPGSGAVSGQVLRVCGQNVIGA

Sequences:

>Translated_451_residues
MPSDRYIDFANSDMGRRLVKAVGLPAPTHLERWQAGRLRPVEGTLLISAGPLGDQVRQFASRLTDSLYSFGSDMPGATTW
VSNQGPRLKAVVFDASQILRTDQLRQLRDFFQPLLRNLDHCAHVVILGKAPETLTDPLAASTQQAIEGFSRSLAKEVRNG
ATVKLLQVDDDAQDQLEGALRFFLTPKAAFISGQFVHLSACPSKVQDWTRPLAGLKAVVTGAARGIGASIAETLTRDGAQ
VILLDVPQTKNELEALASRLGGQALALDICAADAPAQLLEHLPDGVDILVHNAGITRDKTLVNMPEDFWDSVLAVNLSAP
QVLTQVLLDAGALKDNARIVLMASISGIAGNRGQTNYTTSKAGLIGFARAMAPGLKSRGISINAVAPGFIETKMTAHMPF
TLREAGRRMSSLGQGGSPQDVAEAVAWFSQPGSGAVSGQVLRVCGQNVIGA
>Mature_450_residues
PSDRYIDFANSDMGRRLVKAVGLPAPTHLERWQAGRLRPVEGTLLISAGPLGDQVRQFASRLTDSLYSFGSDMPGATTWV
SNQGPRLKAVVFDASQILRTDQLRQLRDFFQPLLRNLDHCAHVVILGKAPETLTDPLAASTQQAIEGFSRSLAKEVRNGA
TVKLLQVDDDAQDQLEGALRFFLTPKAAFISGQFVHLSACPSKVQDWTRPLAGLKAVVTGAARGIGASIAETLTRDGAQV
ILLDVPQTKNELEALASRLGGQALALDICAADAPAQLLEHLPDGVDILVHNAGITRDKTLVNMPEDFWDSVLAVNLSAPQ
VLTQVLLDAGALKDNARIVLMASISGIAGNRGQTNYTTSKAGLIGFARAMAPGLKSRGISINAVAPGFIETKMTAHMPFT
LREAGRRMSSLGQGGSPQDVAEAVAWFSQPGSGAVSGQVLRVCGQNVIGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=246, Percent_Identity=37.3983739837398, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI40254992, Length=233, Percent_Identity=33.0472103004292, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=28.8617886178862, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI5031737, Length=282, Percent_Identity=30.8510638297872, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI33667109, Length=228, Percent_Identity=32.0175438596491, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4504505, Length=230, Percent_Identity=27.3913043478261, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=27.1794871794872, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=32.1428571428571, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=29.8913043478261, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=213, Percent_Identity=23.943661971831, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI226371731, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=39.662447257384, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=29.4117647058824, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=30.6122448979592, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=26.1410788381743, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=30.1255230125523, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=32.046332046332, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=27.1255060728745, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=24.8, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787526, Length=191, Percent_Identity=30.3664921465969, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=37.7593360995851, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17555706, Length=236, Percent_Identity=35.5932203389831, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=25.5060728744939, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=29.0155440414508, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=187, Percent_Identity=28.3422459893048, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=25.9109311740891, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=209, Percent_Identity=28.2296650717703, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=223, Percent_Identity=31.390134529148, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=35.1239669421488, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI23397609, Length=238, Percent_Identity=31.9327731092437, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21355319, Length=240, Percent_Identity=30, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI18859837, Length=187, Percent_Identity=34.7593582887701, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=29.7619047619048, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=237, Percent_Identity=26.5822784810127, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=30.241935483871, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357041, Length=232, Percent_Identity=30.1724137931034, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584744, Length=191, Percent_Identity=29.3193717277487, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574402, Length=191, Percent_Identity=29.3193717277487, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 47940; Mature: 47809

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSDRYIDFANSDMGRRLVKAVGLPAPTHLERWQAGRLRPVEGTLLISAGPLGDQVRQFA
CCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHH
SRLTDSLYSFGSDMPGATTWVSNQGPRLKAVVFDASQILRTDQLRQLRDFFQPLLRNLDH
HHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
CAHVVILGKAPETLTDPLAASTQQAIEGFSRSLAKEVRNGATVKLLQVDDDAQDQLEGAL
HEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHH
RFFLTPKAAFISGQFVHLSACPSKVQDWTRPLAGLKAVVTGAARGIGASIAETLTRDGAQ
HHHCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCE
VILLDVPQTKNELEALASRLGGQALALDICAADAPAQLLEHLPDGVDILVHNAGITRDKT
EEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCCCCCE
LVNMPEDFWDSVLAVNLSAPQVLTQVLLDAGALKDNARIVLMASISGIAGNRGQTNYTTS
EECCCHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
KAGLIGFARAMAPGLKSRGISINAVAPGFIETKMTAHMPFTLREAGRRMSSLGQGGSPQD
HHHHHHHHHHHCCCHHHCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHH
VAEAVAWFSQPGSGAVSGQVLRVCGQNVIGA
HHHHHHHHCCCCCCCHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
PSDRYIDFANSDMGRRLVKAVGLPAPTHLERWQAGRLRPVEGTLLISAGPLGDQVRQFA
CCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHH
SRLTDSLYSFGSDMPGATTWVSNQGPRLKAVVFDASQILRTDQLRQLRDFFQPLLRNLDH
HHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
CAHVVILGKAPETLTDPLAASTQQAIEGFSRSLAKEVRNGATVKLLQVDDDAQDQLEGAL
HEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHH
RFFLTPKAAFISGQFVHLSACPSKVQDWTRPLAGLKAVVTGAARGIGASIAETLTRDGAQ
HHHCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCE
VILLDVPQTKNELEALASRLGGQALALDICAADAPAQLLEHLPDGVDILVHNAGITRDKT
EEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCCCCCE
LVNMPEDFWDSVLAVNLSAPQVLTQVLLDAGALKDNARIVLMASISGIAGNRGQTNYTTS
EECCCHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
KAGLIGFARAMAPGLKSRGISINAVAPGFIETKMTAHMPFTLREAGRRMSSLGQGGSPQD
HHHHHHHHHHHCCCHHHCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHH
VAEAVAWFSQPGSGAVSGQVLRVCGQNVIGA
HHHHHHHHCCCCCCCHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]