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The map label for this gene is pyrR [H]

Identifier: 66043750

GI number: 66043750

Start: 521492

End: 522004

Strand: Reverse

Name: pyrR [H]

Synonym: Psyr_0483

Alternate gene names: 66043750

Gene position: 522004-521492 (Counterclockwise)

Preceding gene: 66043751

Following gene: 66043749

Centisome position: 8.57

GC content: 63.55

Gene sequence:

>513_bases
ATGAGCCTGCCCGATCCCGCCGAACTGATTCGTCAGATGGCCACTGACCTGAACGCTCACCTGAGCAAGCGCGGCATCAG
CGACCCTCGTTTCATCGGCATCCGCACTGGCGGTGTCTGGGTTGCCCAGGCGCTGCTCAAGGCACTGAACAACCCCGCTC
CGCTGGGCACCCTGGACGTTTCGTTCTATCGCGATGATTTCAGCCAGAACGGCCTGCACCCGCAAGTGCGCCCTTCTGAA
CTGCCGTTCGAGATCGAAGGCCAGCACCTGGTGCTGATCGATGACGTGCTGATGAGCGGCCGTACCGTCCGCGCTGCACT
CAACGAACTGTTCGATTACGGCCGCCCGGCCAGTGTCACGCTGGTCTGCCTGCTGGACCTGGACGCCGGTGAACTGCCGG
TACGTCCGAACGTGGTCGGCGCCACCCTGTCGCTGGCACCGGATGAACGCATCAAGCTGTCCGGCCCCGAGCCGCTGGCG
CTCGAACTTCAAGACCTCTCCACCGCCCTTTAA

Upstream 100 bases:

>100_bases
GACTTTTTCTGCCTTTATCGCTTCGAGATACCCGGATTCCACGTTATCGCTTGAGCATCGCGCCACGGACCGACGCTGCC
CGAGCCTCTAAGGAGCAACC

Downstream 100 bases:

>100_bases
GAGTCCATTGCGATGACGCCTCTCGACGCCAAGCGCCCGCTGCAGCTCAACCACCTGGGCCAGCTGCGCCATTTCCTGTC
TCTGGACGGCTTGCCCCGCG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSLPDPAELIRQMATDLNAHLSKRGISDPRFIGIRTGGVWVAQALLKALNNPAPLGTLDVSFYRDDFSQNGLHPQVRPSE
LPFEIEGQHLVLIDDVLMSGRTVRAALNELFDYGRPASVTLVCLLDLDAGELPVRPNVVGATLSLAPDERIKLSGPEPLA
LELQDLSTAL

Sequences:

>Translated_170_residues
MSLPDPAELIRQMATDLNAHLSKRGISDPRFIGIRTGGVWVAQALLKALNNPAPLGTLDVSFYRDDFSQNGLHPQVRPSE
LPFEIEGQHLVLIDDVLMSGRTVRAALNELFDYGRPASVTLVCLLDLDAGELPVRPNVVGATLSLAPDERIKLSGPEPLA
LELQDLSTAL
>Mature_169_residues
SLPDPAELIRQMATDLNAHLSKRGISDPRFIGIRTGGVWVAQALLKALNNPAPLGTLDVSFYRDDFSQNGLHPQVRPSEL
PFEIEGQHLVLIDDVLMSGRTVRAALNELFDYGRPASVTLVCLLDLDAGELPVRPNVVGATLSLAPDERIKLSGPEPLAL
ELQDLSTAL

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 18428; Mature: 18297

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPDPAELIRQMATDLNAHLSKRGISDPRFIGIRTGGVWVAQALLKALNNPAPLGTLDV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEH
SFYRDDFSQNGLHPQVRPSELPFEIEGQHLVLIDDVLMSGRTVRAALNELFDYGRPASVT
HEECCCCCCCCCCCCCCCCCCCEEECCCEEEEEEHHHHCCCHHHHHHHHHHHCCCCCCEE
LVCLLDLDAGELPVRPNVVGATLSLAPDERIKLSGPEPLALELQDLSTAL
EEEEEECCCCCCCCCCCEEEEEEEECCCCEEEECCCCCEEEEHHHHHCCC
>Mature Secondary Structure 
SLPDPAELIRQMATDLNAHLSKRGISDPRFIGIRTGGVWVAQALLKALNNPAPLGTLDV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEH
SFYRDDFSQNGLHPQVRPSELPFEIEGQHLVLIDDVLMSGRTVRAALNELFDYGRPASVT
HEECCCCCCCCCCCCCCCCCCCEEECCCEEEEEEHHHHCCCHHHHHHHHHHHCCCCCCEE
LVCLLDLDAGELPVRPNVVGATLSLAPDERIKLSGPEPLALELQDLSTAL
EEEEEECCCCCCCCCCCEEEEEEEECCCCEEEECCCCCEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA