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The map label for this gene is yggW [H]

Identifier: 66043738

GI number: 66043738

Start: 510393

End: 511607

Strand: Reverse

Name: yggW [H]

Synonym: Psyr_0471

Alternate gene names: 66043738

Gene position: 511607-510393 (Counterclockwise)

Preceding gene: 66043739

Following gene: 66043737

Centisome position: 8.4

GC content: 61.15

Gene sequence:

>1215_bases
ATGACCCACGATTCGCCTGCGCAGCCGCTGTTTCTCGGCGAGAGCGGCTTCTCGTCGGAGAGCCCGCGCCCTGCACTGCC
GCACCTGCCGCCGCTGTCGCTGTACATCCATATTCCGTGGTGCGTGCGCAAATGCCCGTACTGCGACTTCAACTCGCACA
CCGCCAGCCCGGTGCTGCCGGAACAGGAATATGTCGACGCCCTGCTCGCCGACCTCGACCTTGACCTGCCGCACGTCTAC
GGCCGCGAGCTGCAATCGATCTTCTTTGGTGGCGGTACGCCGAGCCTGTTCAGCGCCGATGCGCTGGGGCGCCTGCTGCA
AGGCGTCGAACAGCGCATCCGCTTTGCCAGCGACATCGAGATCACCCTGGAAGCCAACCCCGGCACCTTCGAACAGGTCA
AGTTCAGCGCCTATCGCGGCCTGGGCATCAATCGGTTGTCGATCGGCATTCAGAGCTTTCAGGAATCCAAACTCAAGGCG
CTGGGCCGCATTCATAACGGTGACGAAGCGATTCGTGCTGCCGACATGGCGCGCCGGGCCGGTTTCGACAACTTCAACCT
GGACCTGATGCACGGCCTGCCGGATCAATCCCAGGACGAGGCGCTGGCCGATCTGCGCCAGGCCATTGCCCTCGCGCCGA
CCCACCTGTCCTGGTATCAACTGACCCTGGAGCCCAACACGGTGTTCTGGAATCAGCCACCGGTGCTGCCCGAAGACGAC
ATTCTCTGGGACATTCAGGAAACCGGACAGCAGTTGCTGGCCACTCATGGCTACGCGCAATACGAAGTGTCGGCTTATGC
ACAGCCCGGGAAACCGGCGCGGCATAACCTCAACTATTGGGCGTTCGGTGATTTCATCGGCATCGGCGCAGGCGCACACG
GCAAGCTGAGCCACCCGGACGGGCGCATTGTCCGTACTTGGAAAACCCGGCTGCCCAAGGATTACCTGAACCCGGACAAG
CCGTTTCAGGCCGGTTCCAAGCTGTTGCCGCTCGATGAATTGCCGTTCGAATTCCTGATGAACGCACTGCGACTGACAAA
TGGTGTGGACGCTGCGTTATTTCGCGAAAGAACCGGTCTAAGCCTCGATTCGCTGGCCGAGGCGCGTCGACAGGCTGAAC
AAAAGGGCTTGCTGCACCAGGACCCGACACGCCTGATCGCCACGCCACAAGGCCAGCTGTTCCTCAATGACCTGCTGCAA
TACTTTCTGATCTAA

Upstream 100 bases:

>100_bases
AGCGCAACTGCTCGAGCGCCGAACTGGGCCCGACCGAAAAAAACCAGCTCAGCCACCGCGCCCGCGCCATGGTCCTGTTG
CGGCAACGCCTGGGTCTGCA

Downstream 100 bases:

>100_bases
GGACCCTGCATGGATTTCGTACTCGACTTGCTCGCCACCGTTTCGCGCTGGAGTCGCAGCAATCTCTCGGAAATCGCGCT
CGCGCTGGTGGGCTGCCTGC

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTHDSPAQPLFLGESGFSSESPRPALPHLPPLSLYIHIPWCVRKCPYCDFNSHTASPVLPEQEYVDALLADLDLDLPHVY
GRELQSIFFGGGTPSLFSADALGRLLQGVEQRIRFASDIEITLEANPGTFEQVKFSAYRGLGINRLSIGIQSFQESKLKA
LGRIHNGDEAIRAADMARRAGFDNFNLDLMHGLPDQSQDEALADLRQAIALAPTHLSWYQLTLEPNTVFWNQPPVLPEDD
ILWDIQETGQQLLATHGYAQYEVSAYAQPGKPARHNLNYWAFGDFIGIGAGAHGKLSHPDGRIVRTWKTRLPKDYLNPDK
PFQAGSKLLPLDELPFEFLMNALRLTNGVDAALFRERTGLSLDSLAEARRQAEQKGLLHQDPTRLIATPQGQLFLNDLLQ
YFLI

Sequences:

>Translated_404_residues
MTHDSPAQPLFLGESGFSSESPRPALPHLPPLSLYIHIPWCVRKCPYCDFNSHTASPVLPEQEYVDALLADLDLDLPHVY
GRELQSIFFGGGTPSLFSADALGRLLQGVEQRIRFASDIEITLEANPGTFEQVKFSAYRGLGINRLSIGIQSFQESKLKA
LGRIHNGDEAIRAADMARRAGFDNFNLDLMHGLPDQSQDEALADLRQAIALAPTHLSWYQLTLEPNTVFWNQPPVLPEDD
ILWDIQETGQQLLATHGYAQYEVSAYAQPGKPARHNLNYWAFGDFIGIGAGAHGKLSHPDGRIVRTWKTRLPKDYLNPDK
PFQAGSKLLPLDELPFEFLMNALRLTNGVDAALFRERTGLSLDSLAEARRQAEQKGLLHQDPTRLIATPQGQLFLNDLLQ
YFLI
>Mature_403_residues
THDSPAQPLFLGESGFSSESPRPALPHLPPLSLYIHIPWCVRKCPYCDFNSHTASPVLPEQEYVDALLADLDLDLPHVYG
RELQSIFFGGGTPSLFSADALGRLLQGVEQRIRFASDIEITLEANPGTFEQVKFSAYRGLGINRLSIGIQSFQESKLKAL
GRIHNGDEAIRAADMARRAGFDNFNLDLMHGLPDQSQDEALADLRQAIALAPTHLSWYQLTLEPNTVFWNQPPVLPEDDI
LWDIQETGQQLLATHGYAQYEVSAYAQPGKPARHNLNYWAFGDFIGIGAGAHGKLSHPDGRIVRTWKTRLPKDYLNPDKP
FQAGSKLLPLDELPFEFLMNALRLTNGVDAALFRERTGLSLDSLAEARRQAEQKGLLHQDPTRLIATPQGQLFLNDLLQY
FLI

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=312, Percent_Identity=35.2564102564103, Blast_Score=182, Evalue=6e-46,
Organism=Escherichia coli, GI1789325, Length=380, Percent_Identity=56.3157894736842, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI87082341, Length=278, Percent_Identity=28.4172661870504, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 45103; Mature: 44971

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDSPAQPLFLGESGFSSESPRPALPHLPPLSLYIHIPWCVRKCPYCDFNSHTASPVLP
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCC
EQEYVDALLADLDLDLPHVYGRELQSIFFGGGTPSLFSADALGRLLQGVEQRIRFASDIE
CHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
ITLEANPGTFEQVKFSAYRGLGINRLSIGIQSFQESKLKALGRIHNGDEAIRAADMARRA
EEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GFDNFNLDLMHGLPDQSQDEALADLRQAIALAPTHLSWYQLTLEPNTVFWNQPPVLPEDD
CCCCCCEEHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCCCCCCCC
ILWDIQETGQQLLATHGYAQYEVSAYAQPGKPARHNLNYWAFGDFIGIGAGAHGKLSHPD
EEECHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCEEEECCEEEECCCCCCCCCCCC
GRIVRTWKTRLPKDYLNPDKPFQAGSKLLPLDELPFEFLMNALRLTNGVDAALFRERTGL
CCEEEHHHHHCCHHHCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCC
SLDSLAEARRQAEQKGLLHQDPTRLIATPQGQLFLNDLLQYFLI
CHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
THDSPAQPLFLGESGFSSESPRPALPHLPPLSLYIHIPWCVRKCPYCDFNSHTASPVLP
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCC
EQEYVDALLADLDLDLPHVYGRELQSIFFGGGTPSLFSADALGRLLQGVEQRIRFASDIE
CHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
ITLEANPGTFEQVKFSAYRGLGINRLSIGIQSFQESKLKALGRIHNGDEAIRAADMARRA
EEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GFDNFNLDLMHGLPDQSQDEALADLRQAIALAPTHLSWYQLTLEPNTVFWNQPPVLPEDD
CCCCCCEEHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCCCCCCCC
ILWDIQETGQQLLATHGYAQYEVSAYAQPGKPARHNLNYWAFGDFIGIGAGAHGKLSHPD
EEECHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCEEEECCEEEECCCCCCCCCCCC
GRIVRTWKTRLPKDYLNPDKPFQAGSKLLPLDELPFEFLMNALRLTNGVDAALFRERTGL
CCEEEHHHHHCCHHHCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCC
SLDSLAEARRQAEQKGLLHQDPTRLIATPQGQLFLNDLLQYFLI
CHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]