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The map label for this gene is yggV [C]

Identifier: 66043739

GI number: 66043739

Start: 511604

End: 512197

Strand: Reverse

Name: yggV [C]

Synonym: Psyr_0472

Alternate gene names: 66043739

Gene position: 512197-511604 (Counterclockwise)

Preceding gene: 66043740

Following gene: 66043738

Centisome position: 8.41

GC content: 64.65

Gene sequence:

>594_bases
ATGAACCTCACACAACTCGTACTGGCCAGCCACAATGGCGGCAAACTCAAGGAACTCCAGGCCATGCTCGGCGACAGCGT
AACGCTGCGCTCGGTCAGCGAGTTCAGTCTGGTGGAGCCGGAAGAAACCGGCCTGTCCTTCGTCGAGAATGCGATCCTCA
AGGCACGCAACGCCGCGCGCCTGTCCGGCCTGCCTGCGCTGGCCGACGACTCGGGGCTGGCAGTGGACTTTCTCGGCGGT
GCGCCGGGTATCTATTCAGCACGCTACGCCGATGGCCAGGGCGATGCCGCCAACAACGCCAAGCTGCTGGAGGCGCTTAA
AGACGTGCCGGACGAACAGCGTGGTGCGCAGTTCGTGTGCGTATTGGCACTGGTACGCCACGCCGACGACCCATTGCCGA
TCCTCTGTGAAGGACTGTGGCACGGGCGCATCCTGCACGCCGCCAGCGGCGAACACGGCTTCGGCTATGACCCGCTGTTC
TGGGTGCCGGAGCGCAACTGCTCGAGCGCCGAACTGGGCCCGACCGAAAAAAACCAGCTCAGCCACCGCGCCCGCGCCAT
GGTCCTGTTGCGGCAACGCCTGGGTCTGCAATGA

Upstream 100 bases:

>100_bases
GCTCGGCGAGATCGGCATCTATCGCGTCACAAGCCCCGGGCTGACGGACCACAGGATTGCCGTTTAATCGACCGTTTCCA
AGCACCACGACAGGCCAACC

Downstream 100 bases:

>100_bases
CCCACGATTCGCCTGCGCAGCCGCTGTTTCTCGGCGAGAGCGGCTTCTCGTCGGAGAGCCCGCGCCCTGCACTGCCGCAC
CTGCCGCCGCTGTCGCTGTA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MNLTQLVLASHNGGKLKELQAMLGDSVTLRSVSEFSLVEPEETGLSFVENAILKARNAARLSGLPALADDSGLAVDFLGG
APGIYSARYADGQGDAANNAKLLEALKDVPDEQRGAQFVCVLALVRHADDPLPILCEGLWHGRILHAASGEHGFGYDPLF
WVPERNCSSAELGPTEKNQLSHRARAMVLLRQRLGLQ

Sequences:

>Translated_197_residues
MNLTQLVLASHNGGKLKELQAMLGDSVTLRSVSEFSLVEPEETGLSFVENAILKARNAARLSGLPALADDSGLAVDFLGG
APGIYSARYADGQGDAANNAKLLEALKDVPDEQRGAQFVCVLALVRHADDPLPILCEGLWHGRILHAASGEHGFGYDPLF
WVPERNCSSAELGPTEKNQLSHRARAMVLLRQRLGLQ
>Mature_197_residues
MNLTQLVLASHNGGKLKELQAMLGDSVTLRSVSEFSLVEPEETGLSFVENAILKARNAARLSGLPALADDSGLAVDFLGG
APGIYSARYADGQGDAANNAKLLEALKDVPDEQRGAQFVCVLALVRHADDPLPILCEGLWHGRILHAASGEHGFGYDPLF
WVPERNCSSAELGPTEKNQLSHRARAMVLLRQRLGLQ

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=190, Percent_Identity=52.6315789473684, Blast_Score=202, Evalue=1e-53,
Organism=Drosophila melanogaster, GI19920712, Length=192, Percent_Identity=32.2916666666667, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21165; Mature: 21165

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTQLVLASHNGGKLKELQAMLGDSVTLRSVSEFSLVEPEETGLSFVENAILKARNAAR
CCHHEEEEECCCCCHHHHHHHHHCCCEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHH
LSGLPALADDSGLAVDFLGGAPGIYSARYADGQGDAANNAKLLEALKDVPDEQRGAQFVC
HCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
VLALVRHADDPLPILCEGLWHGRILHAASGEHGFGYDPLFWVPERNCSSAELGPTEKNQL
HHHHHHHCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHH
SHRARAMVLLRQRLGLQ
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLTQLVLASHNGGKLKELQAMLGDSVTLRSVSEFSLVEPEETGLSFVENAILKARNAAR
CCHHEEEEECCCCCHHHHHHHHHCCCEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHH
LSGLPALADDSGLAVDFLGGAPGIYSARYADGQGDAANNAKLLEALKDVPDEQRGAQFVC
HCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
VLALVRHADDPLPILCEGLWHGRILHAASGEHGFGYDPLFWVPERNCSSAELGPTEKNQL
HHHHHHHCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHH
SHRARAMVLLRQRLGLQ
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]