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The map label for this gene is ygbM [C]

Identifier: 66043729

GI number: 66043729

Start: 500492

End: 501277

Strand: Reverse

Name: ygbM [C]

Synonym: Psyr_0462

Alternate gene names: 66043729

Gene position: 501277-500492 (Counterclockwise)

Preceding gene: 66043730

Following gene: 66043727

Centisome position: 8.23

GC content: 61.58

Gene sequence:

>786_bases
ATGCCTCGTTTTGCCGCCAACCTCAGCATGCTGTACCCGCAGCATGATTTTCTTGAGCGCTTTGCCGCAGCCGCTGCCGA
CGGTTTCGGCGCGGTCGAGTACCTGTTTCCTTATGCTTACACGCCGCAGGAGCTCAAGCAGCGCCTGAGCGACAACGGTC
TGGTGCAGGCGCTGTTCAACGCTCCACCGGGCGACTGGGACGCGTGCGAGCGAGGCATTGCCACCCTGCCGGGCCGTGAA
GCGGAATTTCGCAGCGGTATCGAGCGGGCACTGGAATATGCGCAGGTGCTGGGCAATGACCGTGTGCATGTCATGGCCGG
TCTATTGCCTAACGAAGGGTTGCGTGAGCGTCATCAGGCGGTCTATCTGGAGAACCTGGCGTTCGCGGCTGAGCAAGCCA
AGAGCGCAGGCGTCACGATCCTGATCGAGCCGATCAACACCCGCGACATGCCGGGCTTCTTCCTCAACCGCCAGGATCAG
GCGCAGGACATCTGCAAGCTGGTGGGCGCCGACAACCTGAAAGTGCAGTTCGACTGCTACCACTGCCAGATCGTCGAAGG
CGACCTGACGACCAAGCTGCGTCGTGACTTTGCAGGCATCGGCCACATCCAGATCGCCGGGGTGCCGGATCGCAACGAAC
CGGACCTGGGCGAACTGAACTACGAGCACCTGTTCAACGTCATCGACGAACTGGGCTACAGCGGCTGGATCGGTTGCGAA
TATCGCCCGAAAGGCGATACCAGCGAAGGTCTGGCATGGTTGCGCGCGTTGCAGGCCAAGGGCTGA

Upstream 100 bases:

>100_bases
CGCACCTGGACCGTACTGGTCACGCTGCTCGGCACACTGGGCTTTGTGATCACCCTGCTGCTTTGGCCATTCGTCTGACC
CTTTGAAGACTGGAGTTAAC

Downstream 100 bases:

>100_bases
ACCCTGCTTTTATGGATGACGCGGAGCGTCATGAAAGGCATTCCCACGCGGAGCGTGAGGAACGATCATTCTGTAACTGT
CGTGCCCAGGCACGGCAGGT

Product: hydroxypyruvate isomerase

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MPRFAANLSMLYPQHDFLERFAAAAADGFGAVEYLFPYAYTPQELKQRLSDNGLVQALFNAPPGDWDACERGIATLPGRE
AEFRSGIERALEYAQVLGNDRVHVMAGLLPNEGLRERHQAVYLENLAFAAEQAKSAGVTILIEPINTRDMPGFFLNRQDQ
AQDICKLVGADNLKVQFDCYHCQIVEGDLTTKLRRDFAGIGHIQIAGVPDRNEPDLGELNYEHLFNVIDELGYSGWIGCE
YRPKGDTSEGLAWLRALQAKG

Sequences:

>Translated_261_residues
MPRFAANLSMLYPQHDFLERFAAAAADGFGAVEYLFPYAYTPQELKQRLSDNGLVQALFNAPPGDWDACERGIATLPGRE
AEFRSGIERALEYAQVLGNDRVHVMAGLLPNEGLRERHQAVYLENLAFAAEQAKSAGVTILIEPINTRDMPGFFLNRQDQ
AQDICKLVGADNLKVQFDCYHCQIVEGDLTTKLRRDFAGIGHIQIAGVPDRNEPDLGELNYEHLFNVIDELGYSGWIGCE
YRPKGDTSEGLAWLRALQAKG
>Mature_260_residues
PRFAANLSMLYPQHDFLERFAAAAADGFGAVEYLFPYAYTPQELKQRLSDNGLVQALFNAPPGDWDACERGIATLPGREA
EFRSGIERALEYAQVLGNDRVHVMAGLLPNEGLRERHQAVYLENLAFAAEQAKSAGVTILIEPINTRDMPGFFLNRQDQA
QDICKLVGADNLKVQFDCYHCQIVEGDLTTKLRRDFAGIGHIQIAGVPDRNEPDLGELNYEHLFNVIDELGYSGWIGCEY
RPKGDTSEGLAWLRALQAKG

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=261, Percent_Identity=45.2107279693487, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=43.2098765432099, Blast_Score=188, Evalue=4e-48,
Organism=Escherichia coli, GI1789095, Length=257, Percent_Identity=49.8054474708171, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1786718, Length=254, Percent_Identity=48.0314960629921, Blast_Score=247, Evalue=6e-67,
Organism=Caenorhabditis elegans, GI17552022, Length=257, Percent_Identity=38.5214007782101, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17530883, Length=259, Percent_Identity=37.0656370656371, Blast_Score=171, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 29063; Mature: 28932

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLSMLYPQHDFLERFAAAAADGFGAVEYLFPYAYTPQELKQRLSDNGLVQALFN
CCCHHCCHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHCCCCCEEHHHC
APPGDWDACERGIATLPGREAEFRSGIERALEYAQVLGNDRVHVMAGLLPNEGLRERHQA
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
VYLENLAFAAEQAKSAGVTILIEPINTRDMPGFFLNRQDQAQDICKLVGADNLKVQFDCY
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHCCCCHHHHHHHHHHCCCCEEEEEEEE
HCQIVEGDLTTKLRRDFAGIGHIQIAGVPDRNEPDLGELNYEHLFNVIDELGYSGWIGCE
EEEEECCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCE
YRPKGDTSEGLAWLRALQAKG
ECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PRFAANLSMLYPQHDFLERFAAAAADGFGAVEYLFPYAYTPQELKQRLSDNGLVQALFN
CCHHCCHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHCCCCCEEHHHC
APPGDWDACERGIATLPGREAEFRSGIERALEYAQVLGNDRVHVMAGLLPNEGLRERHQA
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
VYLENLAFAAEQAKSAGVTILIEPINTRDMPGFFLNRQDQAQDICKLVGADNLKVQFDCY
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHCCCCHHHHHHHHHHCCCCEEEEEEEE
HCQIVEGDLTTKLRRDFAGIGHIQIAGVPDRNEPDLGELNYEHLFNVIDELGYSGWIGCE
EEEEECCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCE
YRPKGDTSEGLAWLRALQAKG
ECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]