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The map label for this gene is hlyB [H]

Identifier: 66043647

GI number: 66043647

Start: 410246

End: 412162

Strand: Reverse

Name: hlyB [H]

Synonym: Psyr_0380

Alternate gene names: 66043647

Gene position: 412162-410246 (Counterclockwise)

Preceding gene: 66043648

Following gene: 66043646

Centisome position: 6.76

GC content: 60.15

Gene sequence:

>1917_bases
ATGTCTCGTGGGTTATCCAAAAGCCTCGCCAATGCGAGTGTCAGCCTCAAATTGGCGATCGGCTTTGGTCTGGTGCTGTT
GATGACGCTGATGATTTCAGCCACCGGCTGGTTCAGCAATCAGGCCCTGATCGATCGTGGGGACCGTGTCACTGCGATTG
CAGAGGTCAATGAGCTGACCCTTCAGTTGCGCATCAACCGTATGAGCTACGAGGTGCTGTACAACGCAGAGACTGCAGCG
AAGGTCAGAAGTACACTCGATGAGCTCGACGCCGCACTGCAAACCGCCAGAAACCTGCTGCGATCCCCCGAGAACCTGCA
GTTGCTGGATGTCCAGATTCAGGCCACTCGCGACTATCGCCAGTCGTTCGAGGACATGAGCAAGGCAATCGATACCCGCG
AAGCCAGCCGCAGCCAGATGGGCGAAAACGCCGACAAGGCAGTGGATCAGGCCAACAGGATCGAAGCCGAACTGCTCAAG
GAAGATAACATCCTCGCCTTCAATGGCATCGTCGGCGTCAGCAAGCTGATTCAGCAGGCGCGCTTTCAGGTACGTGGTTA
CACCTACAGCGGCCGTCCCGATTTCGAAAAGGACGCCAATAAAGCCATCGATGATGCTGTGACCGGAATCAACACGCTGG
CTGGCGACATTTCTTCCACTTATTCGCCCATGCTGCAACAGGCCATCGCCGGGCTGAATGGCTACCGCGCGGCTGTGGGC
AAATACCGCGATGCCCAGGCCGCCTCCAAGGCCGCACTGGATAAAATGACCACGCTGGGCGTCAGCATGCTCGCCACCAG
CAACGACCTGATTACCCGACAGAACAAGAGCCGCGACGCAGACAGCGCCAAGTCGGTCCAGATGATCATCGCCGCGACTG
CGCTGGCAATGGTGCTTGGCATCCTCGCGGCCTGGGTCATCACTCGCCAGATCACCACCCCGCTACAGGAGACACTCGAA
GTAGTGGAGCGGGTCGCCTCGGGTGACCTGAGCCGCAACCTCAACGTTGATCGCAAGGACGAGCTGGGCAAGCTGCAGGC
CACGATTCAGCGCATGACGGTCAGTCTGCGCGAACTGGTCGGCGGGATTCGCGATGGTGTCACCCAGATTGCCAGCGCAG
CGGAAGAGCTGTCGGCGGTTACCGAGCAGACCAGTGCCGGGGTCAACAGCCAGAAGGTCGAGACCGATCAGGTCGCTACT
GCCATGCATGAAATGACGGCGACCGTTCAGGAGGTCGCGCGCAATGCCGAGGAAGCCTCGGAAGCAGCAGTGGCGGCAGA
CCGTCAGGCCCGTGATGGCGAACGGGTGGTCAACGAGGCCATTGCGCAAATCGAACGTCTCGCTTCTGCGGTGGGCAACT
CCAGCGAAGCGATGGGCGCGCTGAAACAGGAAAGCGACAAGATCGGCAGCGTGCTGGACGTCATCAAATCGGTCGCCGAA
CAGACCAACCTGCTGGCGTTGAACGCCGCTATCGAGGCAGCACGCGCCGGTGAGGCCGGTCGGGGCTTTGCGGTGGTTGC
CGATGAAGTGCGCAGCCTGGCGCAACGCACGCAAAAATCCACTGAAGAAATCGAAGCGCTTATTGCCCGCCTGCAAAGCG
GCACACAACAGGCCACCACCGTCATGGACAGCAGCCGCGAGCTGAGCACCAGCAGCGTGGAACTGACCCGCAGGGCCGGT
GGATCGCTGGCGAACATCACCAAAACCGTCTCGTCGATCCAGGCCATGAACCAGCAGATTGCGGCTGCCGCCGAAGAACA
GAGCGCGACCGCCGAAGAGATCAACCGCAGCATCATCAATGTCCGTGACGTGTCCGAACAGACCTCTGCAGCCAGTGAAG
AAACCGCGGCGTCCAGTGTAGAACTGGCGAGACTGGGCAATCACCTTCAGGTGCTGGTGAGCCGCTTCACCGTCTGA

Upstream 100 bases:

>100_bases
CGCTTGTTCTAAGCTGTCAGTGTCGACTAAATCGCTTCAGTTAACCGATAACTGGCCGATGCAGTCGGATACTTAGGACA
AAAGATGTCAAGGAGTGATC

Downstream 100 bases:

>100_bases
CCTGTCAGGACACAGCCCGCGTCAGCACTCGGCGCGGGCCATTTTTCCCGACAAAATGTGACACCTTTCACCCCTCCTCC
CTGCTCGGAAATCTCCTACG

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MSRGLSKSLANASVSLKLAIGFGLVLLMTLMISATGWFSNQALIDRGDRVTAIAEVNELTLQLRINRMSYEVLYNAETAA
KVRSTLDELDAALQTARNLLRSPENLQLLDVQIQATRDYRQSFEDMSKAIDTREASRSQMGENADKAVDQANRIEAELLK
EDNILAFNGIVGVSKLIQQARFQVRGYTYSGRPDFEKDANKAIDDAVTGINTLAGDISSTYSPMLQQAIAGLNGYRAAVG
KYRDAQAASKAALDKMTTLGVSMLATSNDLITRQNKSRDADSAKSVQMIIAATALAMVLGILAAWVITRQITTPLQETLE
VVERVASGDLSRNLNVDRKDELGKLQATIQRMTVSLRELVGGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVAT
AMHEMTATVQEVARNAEEASEAAVAADRQARDGERVVNEAIAQIERLASAVGNSSEAMGALKQESDKIGSVLDVIKSVAE
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEALIARLQSGTQQATTVMDSSRELSTSSVELTRRAG
GSLANITKTVSSIQAMNQQIAAAAEEQSATAEEINRSIINVRDVSEQTSAASEETAASSVELARLGNHLQVLVSRFTV

Sequences:

>Translated_638_residues
MSRGLSKSLANASVSLKLAIGFGLVLLMTLMISATGWFSNQALIDRGDRVTAIAEVNELTLQLRINRMSYEVLYNAETAA
KVRSTLDELDAALQTARNLLRSPENLQLLDVQIQATRDYRQSFEDMSKAIDTREASRSQMGENADKAVDQANRIEAELLK
EDNILAFNGIVGVSKLIQQARFQVRGYTYSGRPDFEKDANKAIDDAVTGINTLAGDISSTYSPMLQQAIAGLNGYRAAVG
KYRDAQAASKAALDKMTTLGVSMLATSNDLITRQNKSRDADSAKSVQMIIAATALAMVLGILAAWVITRQITTPLQETLE
VVERVASGDLSRNLNVDRKDELGKLQATIQRMTVSLRELVGGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVAT
AMHEMTATVQEVARNAEEASEAAVAADRQARDGERVVNEAIAQIERLASAVGNSSEAMGALKQESDKIGSVLDVIKSVAE
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEALIARLQSGTQQATTVMDSSRELSTSSVELTRRAG
GSLANITKTVSSIQAMNQQIAAAAEEQSATAEEINRSIINVRDVSEQTSAASEETAASSVELARLGNHLQVLVSRFTV
>Mature_637_residues
SRGLSKSLANASVSLKLAIGFGLVLLMTLMISATGWFSNQALIDRGDRVTAIAEVNELTLQLRINRMSYEVLYNAETAAK
VRSTLDELDAALQTARNLLRSPENLQLLDVQIQATRDYRQSFEDMSKAIDTREASRSQMGENADKAVDQANRIEAELLKE
DNILAFNGIVGVSKLIQQARFQVRGYTYSGRPDFEKDANKAIDDAVTGINTLAGDISSTYSPMLQQAIAGLNGYRAAVGK
YRDAQAASKAALDKMTTLGVSMLATSNDLITRQNKSRDADSAKSVQMIIAATALAMVLGILAAWVITRQITTPLQETLEV
VERVASGDLSRNLNVDRKDELGKLQATIQRMTVSLRELVGGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVATA
MHEMTATVQEVARNAEEASEAAVAADRQARDGERVVNEAIAQIERLASAVGNSSEAMGALKQESDKIGSVLDVIKSVAEQ
TNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEALIARLQSGTQQATTVMDSSRELSTSSVELTRRAGG
SLANITKTVSSIQAMNQQIAAAAEEQSATAEEINRSIINVRDVSEQTSAASEETAASSVELARLGNHLQVLVSRFTV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=335, Percent_Identity=36.4179104477612, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI2367378, Length=331, Percent_Identity=32.9305135951662, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788195, Length=307, Percent_Identity=33.5504885993485, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788194, Length=343, Percent_Identity=32.0699708454811, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1789453, Length=344, Percent_Identity=27.0348837209302, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68344; Mature: 68212

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGLSKSLANASVSLKLAIGFGLVLLMTLMISATGWFSNQALIDRGDRVTAIAEVNELT
CCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEHHHHHHH
LQLRINRMSYEVLYNAETAAKVRSTLDELDAALQTARNLLRSPENLQLLDVQIQATRDYR
EEEEEEHHHEEHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHH
QSFEDMSKAIDTREASRSQMGENADKAVDQANRIEAELLKEDNILAFNGIVGVSKLIQQA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
RFQVRGYTYSGRPDFEKDANKAIDDAVTGINTLAGDISSTYSPMLQQAIAGLNGYRAAVG
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KYRDAQAASKAALDKMTTLGVSMLATSNDLITRQNKSRDADSAKSVQMIIAATALAMVLG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILAAWVITRQITTPLQETLEVVERVASGDLSRNLNVDRKDELGKLQATIQRMTVSLRELV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVATAMHEMTATVQEVARNAEEAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAVAADRQARDGERVVNEAIAQIERLASAVGNSSEAMGALKQESDKIGSVLDVIKSVAE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEALIARLQSGTQQATT
HHCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VMDSSRELSTSSVELTRRAGGSLANITKTVSSIQAMNQQIAAAAEEQSATAEEINRSIIN
HHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VRDVSEQTSAASEETAASSVELARLGNHLQVLVSRFTV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRGLSKSLANASVSLKLAIGFGLVLLMTLMISATGWFSNQALIDRGDRVTAIAEVNELT
CCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEHHHHHHH
LQLRINRMSYEVLYNAETAAKVRSTLDELDAALQTARNLLRSPENLQLLDVQIQATRDYR
EEEEEEHHHEEHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHH
QSFEDMSKAIDTREASRSQMGENADKAVDQANRIEAELLKEDNILAFNGIVGVSKLIQQA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
RFQVRGYTYSGRPDFEKDANKAIDDAVTGINTLAGDISSTYSPMLQQAIAGLNGYRAAVG
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KYRDAQAASKAALDKMTTLGVSMLATSNDLITRQNKSRDADSAKSVQMIIAATALAMVLG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILAAWVITRQITTPLQETLEVVERVASGDLSRNLNVDRKDELGKLQATIQRMTVSLRELV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GGIRDGVTQIASAAEELSAVTEQTSAGVNSQKVETDQVATAMHEMTATVQEVARNAEEAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAVAADRQARDGERVVNEAIAQIERLASAVGNSSEAMGALKQESDKIGSVLDVIKSVAE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEALIARLQSGTQQATT
HHCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VMDSSRELSTSSVELTRRAGGSLANITKTVSSIQAMNQQIAAAAEEQSATAEEINRSIIN
HHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VRDVSEQTSAASEETAASSVELARLGNHLQVLVSRFTV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]