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The map label for this gene is hlyB [H]

Identifier: 66043646

GI number: 66043646

Start: 408100

End: 410043

Strand: Reverse

Name: hlyB [H]

Synonym: Psyr_0379

Alternate gene names: 66043646

Gene position: 410043-408100 (Counterclockwise)

Preceding gene: 66043647

Following gene: 66043641

Centisome position: 6.73

GC content: 60.13

Gene sequence:

>1944_bases
ATGTTCCGACTGATCAATCAAGCGCTCGGCAACATGAACGTCAGATTCAAACTGTCCCTGGGTTTCGGCCTGGTGCTGTT
ATTGACGCTGATCATCACACTGACGGGCTGGCATGGCCTGTACACCATGATCGACCGCTCGGAGTCGCTCTCGGACATCG
CCCAGCTCAACGGTCTGACCAAAGATCTGCGCGCCGAGCGAATCACCGACCGCGTCCAGAAAACGCCGGAGAGTACGGCG
CTGGTTACAGAAAAGCTCAATGAAATGAAAGCCCAGCTCACCCTGCTGCACAAGCAGAGTGACGAGGAGGCAACCATCAA
GCTGCTCAACGGGCAGTTCGAGACGCTGAACAGGATCGAAAAGACCTTCGCGGACGTTCGCGACAACCGACAGACCCGCA
ACCAGATACGCACGCGCCTGGAGCAGACCTCGGAACAGGCCTTGCAGGCCATCGCGCAGGTTGAGGTAGAAGTGCTCAAA
AGCGTCAGCCAGGAACAGGACAGCAGCGAGCGGATGGAGGAATTCACCAATATTTCCCAACTGAGGCAGCAGGTCCAGAC
CGCTCGTTATCAAGTGCAGACGTATACCTTCACCACCCGCGACGCCGATGAAAGCGCAGCCATTGCGGCCATCGACGAAG
CGCTCAAGGAAATCGGGCAGATCGCTCAGGATCAGGGCAACGAAAGCCTTCAGGGCCTGACACCGGCGACCGCAGCCCTG
CAGAGTTATCGCGAACGGCTTGGCGAGTTCAAGCAGATACAGACCAAGGCCGAAGCGGATCAGGAAATCATGGAAGGCCT
TGGCGAAACGCTGCTGGACTCCGTCGGCGCGCTGAATCACCTGCAGACTGCACAGCGCGACAGCGAGGCGGCTAATTCCA
GCGCCATGCTGAGCAGTGTTGCAGGTCTGGCTCTGCTGATCGGATTGCTTGCCGCCTGGATCATGACCCGACAGATCACC
GTGCCGTTGCAGCAGACACTCAGTGCCGCAGCGCGCATCGCTCAGGGCGATCTGAGCCGGGACATATCGGTCACACGCCG
TGACGAAATGGGTCAGTTACAAGGCAGCATGCAGACCATGACCGTCAGCCTGCGCGAACTGGTTGGCGGCATCAGCGAGG
GCGTGTCGCAGATCGCCAGCGCGGCCGAACAGTTATCCGCGGTGACCAAACAGACCTGCATCGGAGTCACCAGCCAAAAA
GACGAAACCGACCAGGTGGCCACGGCCATGAATGAAATGGCCGCGACCGTGCAGGAAGTCGCGCGCAATGCGCAAGAAGC
TTCGCAGGCAGCCGCTCAGGCGGATCAACAGGCGCGCAGCGGCGATGAAGTGGTCGGGCAGGCGATCACACAGATCGAGC
AACTGGCTCGCGAAGTGCTGAACTCCACGCAGTCGATGAGCGCGCTCAAGCAGGAAAGCAACAAGATCGTCGGCGTTCTT
GACGTGATCAAGTCTGTTTCACAGCAGACCAATCTGCTGGCTCTCAATGCGGCGATTGAAGCAGCCCGCGCGGGAGAGGC
CGGGCGCGGCTTCGCGGTGGTTGCCGATGAAGTGCGTGGTCTGGCGCAGCGCACGCAAAAGTCCACCGAGGAAATCGAAG
AGCTGATCGCCGCCCTGCAAACCGGCACACAACAGGTCGCGACCACTCTGGACAGCAGCCGCACCCTGACTGACAACACG
GTTGAACTGAGCCGTCGTGCCGGTGGCGCACTGGAGCAGATCACCCGCACCGTGGCGACGATCCAGCACATGAACGAACA
GATCGCTACCGCCAGCGAGGAACAGAGCGTGGTCGCCGAACAGATCAACCGTAACGTCATCAGCGTACGCGACATCTCCG
AACAAACCGCCGCAGCCAGCGAGCAAACCGCCGCCTCCAGCGTCGAACTCGCCAGACTGGGAACCCACCTGCAGACACTG
GTGGGGAAATTCAGGGTGGGTTGA

Upstream 100 bases:

>100_bases
CTTCTCAGGTCACGCAATGAATCGCCACGCCGATGCGCTCACAACGCATGTCCCGACGGGTTCGGAACGTGCTTTTGTTC
GCTCATTGCAGGAGATTCCA

Downstream 100 bases:

>100_bases
TAGATCTGCGACGCAAGGATTCCGACGCTGGAGCGCTTGGCGTTATACACCAGCCTGCTTTTGATTCTGCCCAACGGGCG
TAGGAGCGGACTTGTCCGCG

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MFRLINQALGNMNVRFKLSLGFGLVLLLTLIITLTGWHGLYTMIDRSESLSDIAQLNGLTKDLRAERITDRVQKTPESTA
LVTEKLNEMKAQLTLLHKQSDEEATIKLLNGQFETLNRIEKTFADVRDNRQTRNQIRTRLEQTSEQALQAIAQVEVEVLK
SVSQEQDSSERMEEFTNISQLRQQVQTARYQVQTYTFTTRDADESAAIAAIDEALKEIGQIAQDQGNESLQGLTPATAAL
QSYRERLGEFKQIQTKAEADQEIMEGLGETLLDSVGALNHLQTAQRDSEAANSSAMLSSVAGLALLIGLLAAWIMTRQIT
VPLQQTLSAAARIAQGDLSRDISVTRRDEMGQLQGSMQTMTVSLRELVGGISEGVSQIASAAEQLSAVTKQTCIGVTSQK
DETDQVATAMNEMAATVQEVARNAQEASQAAAQADQQARSGDEVVGQAITQIEQLAREVLNSTQSMSALKQESNKIVGVL
DVIKSVSQQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEELIAALQTGTQQVATTLDSSRTLTDNT
VELSRRAGGALEQITRTVATIQHMNEQIATASEEQSVVAEQINRNVISVRDISEQTAAASEQTAASSVELARLGTHLQTL
VGKFRVG

Sequences:

>Translated_647_residues
MFRLINQALGNMNVRFKLSLGFGLVLLLTLIITLTGWHGLYTMIDRSESLSDIAQLNGLTKDLRAERITDRVQKTPESTA
LVTEKLNEMKAQLTLLHKQSDEEATIKLLNGQFETLNRIEKTFADVRDNRQTRNQIRTRLEQTSEQALQAIAQVEVEVLK
SVSQEQDSSERMEEFTNISQLRQQVQTARYQVQTYTFTTRDADESAAIAAIDEALKEIGQIAQDQGNESLQGLTPATAAL
QSYRERLGEFKQIQTKAEADQEIMEGLGETLLDSVGALNHLQTAQRDSEAANSSAMLSSVAGLALLIGLLAAWIMTRQIT
VPLQQTLSAAARIAQGDLSRDISVTRRDEMGQLQGSMQTMTVSLRELVGGISEGVSQIASAAEQLSAVTKQTCIGVTSQK
DETDQVATAMNEMAATVQEVARNAQEASQAAAQADQQARSGDEVVGQAITQIEQLAREVLNSTQSMSALKQESNKIVGVL
DVIKSVSQQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEELIAALQTGTQQVATTLDSSRTLTDNT
VELSRRAGGALEQITRTVATIQHMNEQIATASEEQSVVAEQINRNVISVRDISEQTAAASEQTAASSVELARLGTHLQTL
VGKFRVG
>Mature_647_residues
MFRLINQALGNMNVRFKLSLGFGLVLLLTLIITLTGWHGLYTMIDRSESLSDIAQLNGLTKDLRAERITDRVQKTPESTA
LVTEKLNEMKAQLTLLHKQSDEEATIKLLNGQFETLNRIEKTFADVRDNRQTRNQIRTRLEQTSEQALQAIAQVEVEVLK
SVSQEQDSSERMEEFTNISQLRQQVQTARYQVQTYTFTTRDADESAAIAAIDEALKEIGQIAQDQGNESLQGLTPATAAL
QSYRERLGEFKQIQTKAEADQEIMEGLGETLLDSVGALNHLQTAQRDSEAANSSAMLSSVAGLALLIGLLAAWIMTRQIT
VPLQQTLSAAARIAQGDLSRDISVTRRDEMGQLQGSMQTMTVSLRELVGGISEGVSQIASAAEQLSAVTKQTCIGVTSQK
DETDQVATAMNEMAATVQEVARNAQEASQAAAQADQQARSGDEVVGQAITQIEQLAREVLNSTQSMSALKQESNKIVGVL
DVIKSVSQQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEELIAALQTGTQQVATTLDSSRTLTDNT
VELSRRAGGALEQITRTVATIQHMNEQIATASEEQSVVAEQINRNVISVRDISEQTAAASEQTAASSVELARLGTHLQTL
VGKFRVG

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=348, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI2367378, Length=362, Percent_Identity=32.8729281767956, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788194, Length=341, Percent_Identity=32.5513196480938, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788195, Length=307, Percent_Identity=31.9218241042345, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1789453, Length=341, Percent_Identity=29.9120234604106, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70239; Mature: 70239

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRLINQALGNMNVRFKLSLGFGLVLLLTLIITLTGWHGLYTMIDRSESLSDIAQLNGLT
CHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHCCCH
KDLRAERITDRVQKTPESTALVTEKLNEMKAQLTLLHKQSDEEATIKLLNGQFETLNRIE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHH
KTFADVRDNRQTRNQIRTRLEQTSEQALQAIAQVEVEVLKSVSQEQDSSERMEEFTNISQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LRQQVQTARYQVQTYTFTTRDADESAAIAAIDEALKEIGQIAQDQGNESLQGLTPATAAL
HHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
QSYRERLGEFKQIQTKAEADQEIMEGLGETLLDSVGALNHLQTAQRDSEAANSSAMLSSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLALLIGLLAAWIMTRQITVPLQQTLSAAARIAQGDLSRDISVTRRDEMGQLQGSMQTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TVSLRELVGGISEGVSQIASAAEQLSAVTKQTCIGVTSQKDETDQVATAMNEMAATVQEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ARNAQEASQAAAQADQQARSGDEVVGQAITQIEQLAREVLNSTQSMSALKQESNKIVGVL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DVIKSVSQQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEELIAALQ
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGTQQVATTLDSSRTLTDNTVELSRRAGGALEQITRTVATIQHMNEQIATASEEQSVVAE
HHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QINRNVISVRDISEQTAAASEQTAASSVELARLGTHLQTLVGKFRVG
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFRLINQALGNMNVRFKLSLGFGLVLLLTLIITLTGWHGLYTMIDRSESLSDIAQLNGLT
CHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHCCCH
KDLRAERITDRVQKTPESTALVTEKLNEMKAQLTLLHKQSDEEATIKLLNGQFETLNRIE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHH
KTFADVRDNRQTRNQIRTRLEQTSEQALQAIAQVEVEVLKSVSQEQDSSERMEEFTNISQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LRQQVQTARYQVQTYTFTTRDADESAAIAAIDEALKEIGQIAQDQGNESLQGLTPATAAL
HHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
QSYRERLGEFKQIQTKAEADQEIMEGLGETLLDSVGALNHLQTAQRDSEAANSSAMLSSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLALLIGLLAAWIMTRQITVPLQQTLSAAARIAQGDLSRDISVTRRDEMGQLQGSMQTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TVSLRELVGGISEGVSQIASAAEQLSAVTKQTCIGVTSQKDETDQVATAMNEMAATVQEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ARNAQEASQAAAQADQQARSGDEVVGQAITQIEQLAREVLNSTQSMSALKQESNKIVGVL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DVIKSVSQQTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEELIAALQ
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGTQQVATTLDSSRTLTDNTVELSRRAGGALEQITRTVATIQHMNEQIATASEEQSVVAE
HHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QINRNVISVRDISEQTAAASEQTAASSVELARLGTHLQTLVGKFRVG
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]