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The map label for this gene is fbp [H]

Identifier: 66043639

GI number: 66043639

Start: 393957

End: 394967

Strand: Reverse

Name: fbp [H]

Synonym: Psyr_0370

Alternate gene names: 66043639

Gene position: 394967-393957 (Counterclockwise)

Preceding gene: 66043640

Following gene: 66043638

Centisome position: 6.48

GC content: 60.93

Gene sequence:

>1011_bases
ATGTCCCGCGTCACACTAAGTCGTTACTTGATTGAGCAGACTCGCAGCAACAACACCCCTGCCGATCTGCGCTTCCTGAT
CGAAGTTGTGGCGCGCGCATGCAAGGAAATCAGCCACGCCGTCTCCAAAGGCGCGCTGGGCGGCGTACTGGGCAGCATGG
GCACCGAAAACGTGCAGGGCGAAGTGCAGAAAAAGCTCGATGTGATCTCCAACGAGATTCTGCTCGAAGCCAACGAATGG
GGCGGTCACCTGGCCGGCATGGCGTCCGAAGAAATGGACAACGCCTACCAGATCCCGGGCAAATACCCGAAGGGTGCCTA
CCTGCTGGTTTTCGACCCGCTGGACGGCTCGTCGAACATCGACATCAACGCACCGGTCGGCACCATCTTCTCGGTACTGC
GCTGCCCGAACGAATACCTGAGCCAGAACGAAGCGCTGAATGAAAAGGCCTTCCTGCAGCCAGGCACCGAACAGGTCGCC
GCCGGTTACGCCATCTACGGCCCGCAAACCATGCTGGTCCTGACCCTGGGCGATGGCGTGAAAGGCTTCACCCTGGACCG
TGAAATGGGCAGCTTCGTGCTGACCCACGAAGACATCACCATCCCGGAGTCCACTCAGGAGTTCGCGGTCAACATGTCCA
ACCAGCGCCACTGGGAAGCCCCGGTACAGCGCTACGTGAGCGAGCTGCTGGCCGGTGAAGACGGTCCGCTGAAAAAGAAC
TACAACATGCGCTGGGTCGCGGCGATGGTGGCCGACGTGCACCGTATCCTGACCCGTGGCGGCCTGTTCATGTACCCGCG
CGACAGCCGCGAGCCTTCCAAGCCGGGTAAACTGCGCCTGATGTACGAAGCCAACCCGATGTCCTTCCTGGTCGAACAGG
CTGGCGGCGCGTCCACTGATGGCCATCAGCGCATTCTCGACATTCAGCCCGAAGGCCTGCACCAGCGCGTAGCGGTGTAC
CTGGGTTCCAAGGAAGAAGTCGAACGCGCCACCGCGTATCACAAGGCGTAA

Upstream 100 bases:

>100_bases
TCTGAACTGAAACAGTCTTAAGCCAGTCTCATAGCAGTATTACGTCGCCACTCGCGTTAAACTGCGCAGGTTTTCATACC
CCCTATTTTCGGAGCTATCC

Downstream 100 bases:

>100_bases
GACGTCTTCTGCACCGCTGGTGATCGGGCCATGCCCGATCACCAGCGCGTGAGCCGATTCTTGAAAAAACGAGCAGTCCG
CCCTTCTGTCAGCCCCTTCT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVISNEILLEANEW
GGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEYLSQNEALNEKAFLQPGTEQVA
AGYAIYGPQTMLVLTLGDGVKGFTLDREMGSFVLTHEDITIPESTQEFAVNMSNQRHWEAPVQRYVSELLAGEDGPLKKN
YNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVY
LGSKEEVERATAYHKA

Sequences:

>Translated_336_residues
MSRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVISNEILLEANEW
GGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEYLSQNEALNEKAFLQPGTEQVA
AGYAIYGPQTMLVLTLGDGVKGFTLDREMGSFVLTHEDITIPESTQEFAVNMSNQRHWEAPVQRYVSELLAGEDGPLKKN
YNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVY
LGSKEEVERATAYHKA
>Mature_335_residues
SRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVISNEILLEANEWG
GHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEYLSQNEALNEKAFLQPGTEQVAA
GYAIYGPQTMLVLTLGDGVKGFTLDREMGSFVLTHEDITIPESTQEFAVNMSNQRHWEAPVQRYVSELLAGEDGPLKKNY
NMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVYL
GSKEEVERATAYHKA

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=325, Percent_Identity=41.5384615384615, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI189083692, Length=324, Percent_Identity=39.8148148148148, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI16579888, Length=324, Percent_Identity=39.8148148148148, Blast_Score=224, Evalue=7e-59,
Organism=Escherichia coli, GI1790679, Length=329, Percent_Identity=42.5531914893617, Blast_Score=257, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI17508131, Length=331, Percent_Identity=41.3897280966767, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6323409, Length=329, Percent_Identity=39.8176291793313, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI19921562, Length=333, Percent_Identity=42.3423423423423, Blast_Score=237, Evalue=7e-63,
Organism=Drosophila melanogaster, GI45550998, Length=333, Percent_Identity=42.3423423423423, Blast_Score=237, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37063; Mature: 36931

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
EVQKKLDVISNEILLEANEWGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNI
HHHHHHHHHCCCEEEEECCCCCHHCCCCHHHCCCEEECCCCCCCCEEEEEEECCCCCCCE
DINAPVGTIFSVLRCPNEYLSQNEALNEKAFLQPGTEQVAAGYAIYGPQTMLVLTLGDGV
EEECCHHHHHHHHHCCHHHHHCCCCCCCHHHCCCCHHHHHCCEEEECCCEEEEEEECCCC
KGFTLDREMGSFVLTHEDITIPESTQEFAVNMSNQRHWEAPVQRYVSELLAGEDGPLKKN
CCEEECCCCCCEEEEECCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCCCCC
YNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTD
CCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCC
GHQRILDIQPEGLHQRVAVYLGSKEEVERATAYHKA
CCCEEEECCCCCHHHEEHEEECCHHHHHHHHHHCCC
>Mature Secondary Structure 
SRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQG
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
EVQKKLDVISNEILLEANEWGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNI
HHHHHHHHHCCCEEEEECCCCCHHCCCCHHHCCCEEECCCCCCCCEEEEEEECCCCCCCE
DINAPVGTIFSVLRCPNEYLSQNEALNEKAFLQPGTEQVAAGYAIYGPQTMLVLTLGDGV
EEECCHHHHHHHHHCCHHHHHCCCCCCCHHHCCCCHHHHHCCEEEECCCEEEEEEECCCC
KGFTLDREMGSFVLTHEDITIPESTQEFAVNMSNQRHWEAPVQRYVSELLAGEDGPLKKN
CCEEECCCCCCEEEEECCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCCCCC
YNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTD
CCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCC
GHQRILDIQPEGLHQRVAVYLGSKEEVERATAYHKA
CCCEEEECCCCCHHHEEHEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA