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The map label for this gene is mdtA [H]

Identifier: 66043614

GI number: 66043614

Start: 367896

End: 368981

Strand: Direct

Name: mdtA [H]

Synonym: Psyr_0345

Alternate gene names: 66043614

Gene position: 367896-368981 (Clockwise)

Preceding gene: 66043613

Following gene: 66043615

Centisome position: 6.04

GC content: 62.15

Gene sequence:

>1086_bases
ATGAAGCGTCGGTCATGTCTGTTGCTGGGCAGCCTGCTGTTAAGCGGCGTTTTATTGAGTGGCTGTGGCAAGGATGAAGC
ACCTCCCGAGCCGGTGCGTCCCGTCGTGTTTGTCGAAGTCCGGCCTGAGTCGAATCAGGATTTCGGGCGTTTCGCCGGCA
ATATCCAGGCGCGTTATCAAAGTGTGCTGGGCTTTCGTGTCGCGGGGCGCATTGCCCGGCGCGATGTTGACGTAGGCGCT
GAAGTCAAGAAAGGCGACTTGCTGGCAACCCTCGATCCGACCGATCAGCAGAACACGGTGCGTGCCCGGCAGGGCGACCT
GGCCAATGTTCAGGCGCAGTTGATCAACGCCCAGGCCAATGCTCGCCGCCAGCAGGAGCTGTTCGATCGCGGCGTCGGTG
CCCAGGCGCAACTGGACATCGCCCTGACCGACCTGAAGACCGCCAGCTCGTCGCAGGAACAGGCCAAGGCCGCGGCTCAA
CAGGCCCGCGATCAATTGAGTTACAGCGAGCTGCGCAGTGATCACGATGCGGTGGTTACCGAGTGGAAAGTCGAAGCCGG
ACAGGTGGTGACAGCCGGTCAGGAAGTCGTGACCCTGGCGCAGCCGGACATCAAGGAAGCGGTGATCGACCTGCCCGATA
CATTGGCCGACCAGTTACCGTCCGACGTGGTATTCACCGTCGCCAGTCAGCTCAATCCGGAAGTGAACACCACCGCCACC
ATTCGCGAAATCGAGCCCCAGGCCGACCGCACCACACGTACGCGACGTGCGCGTCTGTCGCTGGCGCAAACGCCAGCGGC
GTTCCGGCTGGGCACGGCCATCAGCGTAACGCTCAGCTCGACCATCACGCCGCGCATGCGTCTGCCGATCAATGCCCTGC
AGGAAGTCGATGGCAAACGCCAGGTCTGGATCGTCGACTCGCAGAGCCAGACGGTGAACCCCAGAGCGGTGACTATTGCC
AGCCGTGACAGCGACTCCTTCGTGCTGACCGATGGCGTCAAAGCCGGTGAAAAAGTGGTGAGCGCGGGCGTCAACAGCCT
CAAGCCGGGCCAGAAAGTCAAAGTCGATGAGGAAAGCCCGCGATGA

Upstream 100 bases:

>100_bases
GTGGAGAGAAAGTTGTGGTGGCAGGCGGACAGTTGTTACACCCGGACATGCAGGTCGACATTGCCGAACAGCCCAAACCA
CAGAATGCACAGGTGCAGCC

Downstream 100 bases:

>100_bases
AAGGGAATTTCAATCTGTCCGAGTGGGCCATCAAGCACCAGTCGTTCGTCTGGTACCTGATGTTCGTCGCGCTGTTGATG
GGCGTGTTTTCCTACATGAA

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKRRSCLLLGSLLLSGVLLSGCGKDEAPPEPVRPVVFVEVRPESNQDFGRFAGNIQARYQSVLGFRVAGRIARRDVDVGA
EVKKGDLLATLDPTDQQNTVRARQGDLANVQAQLINAQANARRQQELFDRGVGAQAQLDIALTDLKTASSSQEQAKAAAQ
QARDQLSYSELRSDHDAVVTEWKVEAGQVVTAGQEVVTLAQPDIKEAVIDLPDTLADQLPSDVVFTVASQLNPEVNTTAT
IREIEPQADRTTRTRRARLSLAQTPAAFRLGTAISVTLSSTITPRMRLPINALQEVDGKRQVWIVDSQSQTVNPRAVTIA
SRDSDSFVLTDGVKAGEKVVSAGVNSLKPGQKVKVDEESPR

Sequences:

>Translated_361_residues
MKRRSCLLLGSLLLSGVLLSGCGKDEAPPEPVRPVVFVEVRPESNQDFGRFAGNIQARYQSVLGFRVAGRIARRDVDVGA
EVKKGDLLATLDPTDQQNTVRARQGDLANVQAQLINAQANARRQQELFDRGVGAQAQLDIALTDLKTASSSQEQAKAAAQ
QARDQLSYSELRSDHDAVVTEWKVEAGQVVTAGQEVVTLAQPDIKEAVIDLPDTLADQLPSDVVFTVASQLNPEVNTTAT
IREIEPQADRTTRTRRARLSLAQTPAAFRLGTAISVTLSSTITPRMRLPINALQEVDGKRQVWIVDSQSQTVNPRAVTIA
SRDSDSFVLTDGVKAGEKVVSAGVNSLKPGQKVKVDEESPR
>Mature_361_residues
MKRRSCLLLGSLLLSGVLLSGCGKDEAPPEPVRPVVFVEVRPESNQDFGRFAGNIQARYQSVLGFRVAGRIARRDVDVGA
EVKKGDLLATLDPTDQQNTVRARQGDLANVQAQLINAQANARRQQELFDRGVGAQAQLDIALTDLKTASSSQEQAKAAAQ
QARDQLSYSELRSDHDAVVTEWKVEAGQVVTAGQEVVTLAQPDIKEAVIDLPDTLADQLPSDVVFTVASQLNPEVNTTAT
IREIEPQADRTTRTRRARLSLAQTPAAFRLGTAISVTLSSTITPRMRLPINALQEVDGKRQVWIVDSQSQTVNPRAVTIA
SRDSDSFVLTDGVKAGEKVVSAGVNSLKPGQKVKVDEESPR

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=382, Percent_Identity=25.9162303664921, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082036, Length=347, Percent_Identity=26.2247838616715, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786668, Length=383, Percent_Identity=26.1096605744125, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789665, Length=380, Percent_Identity=22.8947368421053, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39050; Mature: 39050

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRSCLLLGSLLLSGVLLSGCGKDEAPPEPVRPVVFVEVRPESNQDFGRFAGNIQARYQ
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
SVLGFRVAGRIARRDVDVGAEVKKGDLLATLDPTDQQNTVRARQGDLANVQAQLINAQAN
HHHHHHHHHHHHHCCCCCCCEECCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHH
ARRQQELFDRGVGAQAQLDIALTDLKTASSSQEQAKAAAQQARDQLSYSELRSDHDAVVT
HHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
EWKVEAGQVVTAGQEVVTLAQPDIKEAVIDLPDTLADQLPSDVVFTVASQLNPEVNTTAT
EEEECCCCEEECCCEEEEECCCCHHHHHHCCCHHHHHHCCCHHHHHHHHHCCCCCCCEEE
IREIEPQADRTTRTRRARLSLAQTPAAFRLGTAISVTLSSTITPRMRLPINALQEVDGKR
EEECCCCCCHHHHHHHHHHHHHCCCCHHEECCEEEEEECCCCCCCEECCHHHHHHCCCCE
QVWIVDSQSQTVNPRAVTIASRDSDSFVLTDGVKAGEKVVSAGVNSLKPGQKVKVDEESP
EEEEEECCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHCHHHCCCCCEEECCCCCC
R
C
>Mature Secondary Structure
MKRRSCLLLGSLLLSGVLLSGCGKDEAPPEPVRPVVFVEVRPESNQDFGRFAGNIQARYQ
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
SVLGFRVAGRIARRDVDVGAEVKKGDLLATLDPTDQQNTVRARQGDLANVQAQLINAQAN
HHHHHHHHHHHHHCCCCCCCEECCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHH
ARRQQELFDRGVGAQAQLDIALTDLKTASSSQEQAKAAAQQARDQLSYSELRSDHDAVVT
HHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
EWKVEAGQVVTAGQEVVTLAQPDIKEAVIDLPDTLADQLPSDVVFTVASQLNPEVNTTAT
EEEECCCCEEECCCEEEEECCCCHHHHHHCCCHHHHHHCCCHHHHHHHHHCCCCCCCEEE
IREIEPQADRTTRTRRARLSLAQTPAAFRLGTAISVTLSSTITPRMRLPINALQEVDGKR
EEECCCCCCHHHHHHHHHHHHHCCCCHHEECCEEEEEECCCCCCCEECCHHHHHHCCCCE
QVWIVDSQSQTVNPRAVTIASRDSDSFVLTDGVKAGEKVVSAGVNSLKPGQKVKVDEESP
EEEEEECCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHCHHHCCCCCEEECCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]