Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 66043613

GI number: 66043613

Start: 366781

End: 367899

Strand: Direct

Name: mdtA [H]

Synonym: Psyr_0344

Alternate gene names: 66043613

Gene position: 366781-367899 (Clockwise)

Preceding gene: 66043612

Following gene: 66043614

Centisome position: 6.02

GC content: 62.47

Gene sequence:

>1119_bases
ATGCCCGTTCGTATTTCAAGACTGGTTACGTTCGGTCTGGCCGCTGCCTTGGCGGCGCTGGCGGGCTGTGGCGAGGAAAA
ACCGGCGGCGCCCGAACTGCCCAGGGTTTACGTGCAGACGGTAAAAAGTGCCGACTTCGCCGCCAGTGTCGCCCTGACCG
GTGATGTTCAGGCGCGGGTGCAGACCCGCCTGTCTTTCCGGGTCAATGGCAAGATCATTCAGCGTAACGTCGATGTGGGC
GACCGGGTCACTGCCCGGCAGGTGCTGGCGCGGCTCGATCCGAAGGATCTGCAGACCAATGTCGATTCGGCCGCTGCTGC
TGTGGCGGCCGAACAGGCCCGCGTGAGCCAGTCCCGCGCTGCGTTTGTCCGTCAGCAAAAGCTGCTGCCCAAGGGTTATA
CCAGTCGCAGCGAATATGACTCGGCCCAGGCCGCCGTGCGTGGCAGCGAGAGTTCGTTGAAAGCGGCGCAGGCGCAACTG
GCCAATGCTCGCGAGCAACTGGGTTATACCGCTCTGGTCGCTGACGCGCCGGGTGTGATCACCGCGCGTCAGGCTGAAGT
CGGGCAAGTGGTGCAGGCCACCATGCCGATTTTCGATCTGGCGCGCGACGGTGATCGCGATGCGGTGTTCAATGTCTACG
AGTCGCTGTTCGTTCAGCCGCCGACCAATCAGGCCGTGCAGGTCACGTTGCTCGATAACCCGAACATCAAGGTCAGCGGC
AAAGTGCGCGAAGTAACCCCGGCGGTGTCGGCGCAGACCGGTACCTTGCAGATCAAGATTGCCCTGGACCCGCTGCCTGA
AGGCATGGACCTGGGCTCGGTGGTCAGCGTGGCGCTGAGCGCACCGGCCAACGCCAGTGTCGAGTTGCCATGGGCGGCGC
TGACCAAGGACCTCGGCGAACAGTTGGGCAAGCCTGCCGTATGGGTGGTGGACGAGCAGGGCAAGGTCAATCTGCGCAAG
GTCACCGTTACCCGTTACCTGACGTCCAAAGTCATCATTGGCGACGGGCTCAAGAGTGGAGAGAAAGTTGTGGTGGCAGG
CGGACAGTTGTTACACCCGGACATGCAGGTCGACATTGCCGAACAGCCCAAACCACAGAATGCACAGGTGCAGCCATGA

Upstream 100 bases:

>100_bases
GCGCCCCCCAATGAACCCTCCCTCTCGCACACAGTCGCATACTCACGCTATTCTCTCGCCCTGATCACGTCCGCATCCGG
CAGTCGCACAAGGAGTCTGC

Downstream 100 bases:

>100_bases
AGCGTCGGTCATGTCTGTTGCTGGGCAGCCTGCTGTTAAGCGGCGTTTTATTGAGTGGCTGTGGCAAGGATGAAGCACCT
CCCGAGCCGGTGCGTCCCGT

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MPVRISRLVTFGLAAALAALAGCGEEKPAAPELPRVYVQTVKSADFAASVALTGDVQARVQTRLSFRVNGKIIQRNVDVG
DRVTARQVLARLDPKDLQTNVDSAAAAVAAEQARVSQSRAAFVRQQKLLPKGYTSRSEYDSAQAAVRGSESSLKAAQAQL
ANAREQLGYTALVADAPGVITARQAEVGQVVQATMPIFDLARDGDRDAVFNVYESLFVQPPTNQAVQVTLLDNPNIKVSG
KVREVTPAVSAQTGTLQIKIALDPLPEGMDLGSVVSVALSAPANASVELPWAALTKDLGEQLGKPAVWVVDEQGKVNLRK
VTVTRYLTSKVIIGDGLKSGEKVVVAGGQLLHPDMQVDIAEQPKPQNAQVQP

Sequences:

>Translated_372_residues
MPVRISRLVTFGLAAALAALAGCGEEKPAAPELPRVYVQTVKSADFAASVALTGDVQARVQTRLSFRVNGKIIQRNVDVG
DRVTARQVLARLDPKDLQTNVDSAAAAVAAEQARVSQSRAAFVRQQKLLPKGYTSRSEYDSAQAAVRGSESSLKAAQAQL
ANAREQLGYTALVADAPGVITARQAEVGQVVQATMPIFDLARDGDRDAVFNVYESLFVQPPTNQAVQVTLLDNPNIKVSG
KVREVTPAVSAQTGTLQIKIALDPLPEGMDLGSVVSVALSAPANASVELPWAALTKDLGEQLGKPAVWVVDEQGKVNLRK
VTVTRYLTSKVIIGDGLKSGEKVVVAGGQLLHPDMQVDIAEQPKPQNAQVQP
>Mature_371_residues
PVRISRLVTFGLAAALAALAGCGEEKPAAPELPRVYVQTVKSADFAASVALTGDVQARVQTRLSFRVNGKIIQRNVDVGD
RVTARQVLARLDPKDLQTNVDSAAAAVAAEQARVSQSRAAFVRQQKLLPKGYTSRSEYDSAQAAVRGSESSLKAAQAQLA
NAREQLGYTALVADAPGVITARQAEVGQVVQATMPIFDLARDGDRDAVFNVYESLFVQPPTNQAVQVTLLDNPNIKVSGK
VREVTPAVSAQTGTLQIKIALDPLPEGMDLGSVVSVALSAPANASVELPWAALTKDLGEQLGKPAVWVVDEQGKVNLRKV
TVTRYLTSKVIIGDGLKSGEKVVVAGGQLLHPDMQVDIAEQPKPQNAQVQP

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=363, Percent_Identity=26.7217630853994, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082036, Length=307, Percent_Identity=27.6872964169381, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789665, Length=376, Percent_Identity=26.8617021276596, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786668, Length=379, Percent_Identity=27.4406332453826, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081796, Length=334, Percent_Identity=24.251497005988, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39424; Mature: 39293

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRISRLVTFGLAAALAALAGCGEEKPAAPELPRVYVQTVKSADFAASVALTGDVQARV
CCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCHHEEE
QTRLSFRVNGKIIQRNVDVGDRVTARQVLARLDPKDLQTNVDSAAAAVAAEQARVSQSRA
EEEEEEEECCEEEEECCCCCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
AFVRQQKLLPKGYTSRSEYDSAQAAVRGSESSLKAAQAQLANAREQLGYTALVADAPGVI
HHHHHHHCCCCCCCCCCHHCHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCE
TARQAEVGQVVQATMPIFDLARDGDRDAVFNVYESLFVQPPTNQAVQVTLLDNPNIKVSG
EECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCEEEEEEECCCCEEEEC
KVREVTPAVSAQTGTLQIKIALDPLPEGMDLGSVVSVALSAPANASVELPWAALTKDLGE
CEEEECCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEECCHHHHHHHHHH
QLGKPAVWVVDEQGKVNLRKVTVTRYLTSKVIIGDGLKSGEKVVVAGGQLLHPDMQVDIA
HHCCCEEEEECCCCCEEEEEEEEEHHHHHEEEEECCCCCCCEEEEECCEEECCCCEEEEC
EQPKPQNAQVQP
CCCCCCCCCCCC
>Mature Secondary Structure 
PVRISRLVTFGLAAALAALAGCGEEKPAAPELPRVYVQTVKSADFAASVALTGDVQARV
CEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCHHEEE
QTRLSFRVNGKIIQRNVDVGDRVTARQVLARLDPKDLQTNVDSAAAAVAAEQARVSQSRA
EEEEEEEECCEEEEECCCCCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
AFVRQQKLLPKGYTSRSEYDSAQAAVRGSESSLKAAQAQLANAREQLGYTALVADAPGVI
HHHHHHHCCCCCCCCCCHHCHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCE
TARQAEVGQVVQATMPIFDLARDGDRDAVFNVYESLFVQPPTNQAVQVTLLDNPNIKVSG
EECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCEEEEEEECCCCEEEEC
KVREVTPAVSAQTGTLQIKIALDPLPEGMDLGSVVSVALSAPANASVELPWAALTKDLGE
CEEEECCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEECCHHHHHHHHHH
QLGKPAVWVVDEQGKVNLRKVTVTRYLTSKVIIGDGLKSGEKVVVAGGQLLHPDMQVDIA
HHCCCEEEEECCCCCEEEEEEEEEHHHHHEEEEECCCCCCCEEEEECCEEECCCCEEEEC
EQPKPQNAQVQP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]