Click here to switch to the map view.

The map label for this gene is znuA [H]

Identifier: 66043545

GI number: 66043545

Start: 293509

End: 294450

Strand: Reverse

Name: znuA [H]

Synonym: Psyr_0275

Alternate gene names: 66043545

Gene position: 294450-293509 (Counterclockwise)

Preceding gene: 66043550

Following gene: 66043544

Centisome position: 4.83

GC content: 63.06

Gene sequence:

>942_bases
GTGCGCCGTCTTTTAAATCTTGCTGCTGTTTTCTGGGTCAGCCTGCTGATCATCTCCCCTGCTCAGGCCGAGGTCCGGGT
GCTGACCAGCATCAAGCCTCTGCAGCTGATTGCGGCGGCTGTACAGGATGGCGTCGGTACACCGGAAGTGCTTCTGCCGC
CGGGTGCCTCACCGCATAACTACGCGCTGCGCCCGTCCGACGTACGGCGTGTACAGGAAGTCGAGTTGCTCTACTGGATC
GGCCCGGACATGGAAACCTTCCTGCCGCGCGTCATTCAGGGCCGCAAACTGCCTGCGGTTGCCGTACAGACACTGCCGGG
CATGCACTTGCGGCACTTTGGCGAAGACAACGCCTCGCATGATGACCACGAGCATGATCACGACAACGACGCAGACGAAC
ATGACCACGACCACCGCCCCGGCAGTCTCGATTCGCACCTGTGGCTGTCGACCGTCAACGCGCGGGTGATCGCCGCAAAA
ATGGCCACTGACCTGAGCGCTGCCGACCCCGCCAACGCAGCCCGCTACGCCAGCAACGCCGAGGCGTTCAGCAAACGTCT
GGATACGCTGGACGCCCGTATCAAGCAGCGTGTCAGCACAGTGGCAGGCAAGCCTTACTTCGTATTCCACGAAGCCTTCG
ATTATTTCGAAGAGGCCTATGGGCTCAAGCATGCCGGGGTATTCGCCATCGCCGCCGAGATCCAGCCCGGCGCCCAGCAC
GTCGCCGCCATGCGCGAACGCCTGAAAGCTGCAGGCAAGACCTGCGTATTCAGCGAACCGCCCCTGCGCCCGCGCCTGGC
CGAAACCCTGAGCGCCGGCCTGCCGGTCAAACTGGCCGAACTGGATGCACTGGGCGGCTACACCCCGGCCACCGCGCAGG
GTTACGAGCAAGTCCTGCAAAAGCTCGCCGACGACCTGGCAGGTTGCCTGAGTAGTCTCTGA

Upstream 100 bases:

>100_bases
ATGGGGGCGACTGGCCAGGGGAGTATTGGGCATGAGCAGCGACGATATTGGCTAGAGACGTTATTATGTTACCCGTTCCT
GGCTGATATGAGTGATTCGA

Downstream 100 bases:

>100_bases
CTGCCACCGCCCACATAGCAGCACTGCTGTGTGACGCGGAGCGTCACGAACTGCATTCCCACGCTGGAGCGTGAGGAACG
ATAGTCGTCAGGGATAACAC

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRRLLNLAAVFWVSLLIISPAQAEVRVLTSIKPLQLIAAAVQDGVGTPEVLLPPGASPHNYALRPSDVRRVQEVELLYWI
GPDMETFLPRVIQGRKLPAVAVQTLPGMHLRHFGEDNASHDDHEHDHDNDADEHDHDHRPGSLDSHLWLSTVNARVIAAK
MATDLSAADPANAARYASNAEAFSKRLDTLDARIKQRVSTVAGKPYFVFHEAFDYFEEAYGLKHAGVFAIAAEIQPGAQH
VAAMRERLKAAGKTCVFSEPPLRPRLAETLSAGLPVKLAELDALGGYTPATAQGYEQVLQKLADDLAGCLSSL

Sequences:

>Translated_313_residues
MRRLLNLAAVFWVSLLIISPAQAEVRVLTSIKPLQLIAAAVQDGVGTPEVLLPPGASPHNYALRPSDVRRVQEVELLYWI
GPDMETFLPRVIQGRKLPAVAVQTLPGMHLRHFGEDNASHDDHEHDHDNDADEHDHDHRPGSLDSHLWLSTVNARVIAAK
MATDLSAADPANAARYASNAEAFSKRLDTLDARIKQRVSTVAGKPYFVFHEAFDYFEEAYGLKHAGVFAIAAEIQPGAQH
VAAMRERLKAAGKTCVFSEPPLRPRLAETLSAGLPVKLAELDALGGYTPATAQGYEQVLQKLADDLAGCLSSL
>Mature_313_residues
MRRLLNLAAVFWVSLLIISPAQAEVRVLTSIKPLQLIAAAVQDGVGTPEVLLPPGASPHNYALRPSDVRRVQEVELLYWI
GPDMETFLPRVIQGRKLPAVAVQTLPGMHLRHFGEDNASHDDHEHDHDNDADEHDHDHRPGSLDSHLWLSTVNARVIAAK
MATDLSAADPANAARYASNAEAFSKRLDTLDARIKQRVSTVAGKPYFVFHEAFDYFEEAYGLKHAGVFAIAAEIQPGAQH
VAAMRERLKAAGKTCVFSEPPLRPRLAETLSAGLPVKLAELDALGGYTPATAQGYEQVLQKLADDLAGCLSSL

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=288, Percent_Identity=37.1527777777778, Blast_Score=195, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34122; Mature: 34122

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLNLAAVFWVSLLIISPAQAEVRVLTSIKPLQLIAAAVQDGVGTPEVLLPPGASPHN
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCCCCCCC
YALRPSDVRRVQEVELLYWIGPDMETFLPRVIQGRKLPAVAVQTLPGMHLRHFGEDNASH
CCCCHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCC
DDHEHDHDNDADEHDHDHRPGSLDSHLWLSTVNARVIAAKMATDLSAADPANAARYASNA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCH
EAFSKRLDTLDARIKQRVSTVAGKPYFVFHEAFDYFEEAYGLKHAGVFAIAAEIQPGAQH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHH
VAAMRERLKAAGKTCVFSEPPLRPRLAETLSAGLPVKLAELDALGGYTPATAQGYEQVLQ
HHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCEEHHHHHHCCCCCCCCHHHHHHHHH
KLADDLAGCLSSL
HHHHHHHHHHHCC
>Mature Secondary Structure
MRRLLNLAAVFWVSLLIISPAQAEVRVLTSIKPLQLIAAAVQDGVGTPEVLLPPGASPHN
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCCCCCCC
YALRPSDVRRVQEVELLYWIGPDMETFLPRVIQGRKLPAVAVQTLPGMHLRHFGEDNASH
CCCCHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCC
DDHEHDHDNDADEHDHDHRPGSLDSHLWLSTVNARVIAAKMATDLSAADPANAARYASNA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCH
EAFSKRLDTLDARIKQRVSTVAGKPYFVFHEAFDYFEEAYGLKHAGVFAIAAEIQPGAQH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHH
VAAMRERLKAAGKTCVFSEPPLRPRLAETLSAGLPVKLAELDALGGYTPATAQGYEQVLQ
HHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCEEHHHHHHCCCCCCCCHHHHHHHHH
KLADDLAGCLSSL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA