Click here to switch to the map view.

The map label for this gene is kinB [H]

Identifier: 66043534

GI number: 66043534

Start: 280205

End: 281992

Strand: Direct

Name: kinB [H]

Synonym: Psyr_0264

Alternate gene names: 66043534

Gene position: 280205-281992 (Clockwise)

Preceding gene: 66043533

Following gene: 66043539

Centisome position: 4.6

GC content: 61.3

Gene sequence:

>1788_bases
ATGAAGCTGGCCATGAAGTTGCGCACCCGCCTCTTTCTGAGCATTTCGGCGCTTATCACGGTCGCTTTGCTTGGATTGCT
GCTGGGGCTCGTCAGTGTCATGCAGATGGCTCGTACTCAGGAATCACTGATTCAGCATAACTTCGCCATCCTCGATCTGG
GCTTGAAGCTGCGCCAGAACATGGGCGATCAGTTGGTGTTGATGACCGGTTCCAGTCGCAATGAGCCTGAGCTGCAAAGA
ATGCAGAAGCAGTTTGAAGAGCTGCTGGAGGAAGGATCGGCGCAGGACACCCAGCAAAATGTGCGCAACGGTTTTGAAAA
GACCCGAGGCGATTATCAGCGATTCATCGCCACCTGGCAGCAATACGGCAATGATCCGCGAGGCATACGCGGCAACTCGC
AATTGAGCGAAAGTTTCGACACGCTGCGTAACGGTCTGATGGATGTGCATCGCAAGGCGTTGGAGAACATCAGCAACGCC
GAGATCAATTCCAGGGATCGAGCATTGTGGATCGCCGGCTTGCTGGGCCTGGTCGGGCTGGCGGTGCTGTGCATCGGTTT
TGTCACCGCGCACGGCATCGCCCGCCGTTTCGGTGCGCCGATCGAGGCGCTGGCCAAGGCCGCCGATCGCATTGGCGAGG
GTGATTACGAGGTCACGCTGCCCATTTCCTCGGCTGCCGAAATGAACCTGCTGACCCGGCGCTTCGGCATCATGGCCGAA
GCCCTGCGTCAGCATCAGGCGACCAACGTCGATGAGCTTCTGGCGGGCCAGCAGCGCCTGCAGGCGGTCCTCGACAGTAT
TGACGATGGCCTGCTGATGATCGATCGGCAAGGCCACCTGGAGCACCTCAACCCTGTTGCGCAGCGTCAGCTCGGATGGG
ACGAGAGTCGCCTCGGGCACAGTCTCGGTGAGGCGTTGGGCCGTCCCGAGCTGGATGAGCAATTGCATCTGGTGCTGCGG
GGCGGAACGCTGGAGCGCGCGCCGGAAGACCTGGCCATCGAAATCGACGGCGAGTCGCGACTGCTGACCTACAGCATGAC
ACCGGTCAGCCACACCAAGGGCCACATCCTGGGTGCGGTGATGGTGCTGCACGACGTGACCGAGCAGCGTGCTTTCGAGC
GGGTACGCAGCGAGTTCGTCCTGCGCGCCTCGCATGAGTTGCGCACCCCGGTCACGGGCATGCACATGGCGTTCGGCCTT
CTTCAGGAGCGTTTGCATTTCGCTCCCGAGTCCCGCGAGGCCGACCTGCTCAATACGGTCACCGAAGAAATGCAGCGCCT
GATGCAGCTCATCAACGACCTGCTGAATTTCTCGCGTTACCAGAACGGTCTGCAGAAGCTCAAACTCGCGCCGTGCTCCA
TCGAAACGTTGCTGCAGGAAGCCAAGGCGCGCTTCGAGGATCAGGCCCAGGAGCAGGATATTGTGCTGATGCTGGATATG
CAGGAGCCGATGCCGCGCCTGCATGCCGATCAGTCTCAGCTGGAGCGGGTACTGGACAATCTGCTGGACAACGCGTTGCG
GCACACGCCGCCGAACGGCCTGATTCGCTTGCAGGCCAGGCGCCACGGCGAGCGGGCGATCATCAGTGTCGAAGACAACG
GCGAGGGCATTGCCTATGGGCAGCAGGGGCGGATCTTCGAGCCCTTCGTCCAGGTCGGCCGCAAGAAAGGCGGCGCCGGG
CTCGGGCTGGCGCTGTGCAAGGAGATTGTCCAGCTGCACGGCGGACGCATGGGCGTTTATTCACGGCCGGGGCAGGGCAC
GCAGTTCTATATGGCGTTACCGCTCTGA

Upstream 100 bases:

>100_bases
GCAACCAGTGAAACCCTTGATCAGGCCGCCAAGACCCTGGGTATCGATGCTTCGACGCTTTACCGCAAACGAAAACAGTA
CAACCTATGAAATACCTCAA

Downstream 100 bases:

>100_bases
GGGCTTGAGCACCAGGCCCTCATCGGTTGACTGAGTATCAGCCTTCACACGTTTCAATTCGAGTGATTGAGCACCTGCAG
GATGGCCGCGCTCTGTGCGT

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MKLAMKLRTRLFLSISALITVALLGLLLGLVSVMQMARTQESLIQHNFAILDLGLKLRQNMGDQLVLMTGSSRNEPELQR
MQKQFEELLEEGSAQDTQQNVRNGFEKTRGDYQRFIATWQQYGNDPRGIRGNSQLSESFDTLRNGLMDVHRKALENISNA
EINSRDRALWIAGLLGLVGLAVLCIGFVTAHGIARRFGAPIEALAKAADRIGEGDYEVTLPISSAAEMNLLTRRFGIMAE
ALRQHQATNVDELLAGQQRLQAVLDSIDDGLLMIDRQGHLEHLNPVAQRQLGWDESRLGHSLGEALGRPELDEQLHLVLR
GGTLERAPEDLAIEIDGESRLLTYSMTPVSHTKGHILGAVMVLHDVTEQRAFERVRSEFVLRASHELRTPVTGMHMAFGL
LQERLHFAPESREADLLNTVTEEMQRLMQLINDLLNFSRYQNGLQKLKLAPCSIETLLQEAKARFEDQAQEQDIVLMLDM
QEPMPRLHADQSQLERVLDNLLDNALRHTPPNGLIRLQARRHGERAIISVEDNGEGIAYGQQGRIFEPFVQVGRKKGGAG
LGLALCKEIVQLHGGRMGVYSRPGQGTQFYMALPL

Sequences:

>Translated_595_residues
MKLAMKLRTRLFLSISALITVALLGLLLGLVSVMQMARTQESLIQHNFAILDLGLKLRQNMGDQLVLMTGSSRNEPELQR
MQKQFEELLEEGSAQDTQQNVRNGFEKTRGDYQRFIATWQQYGNDPRGIRGNSQLSESFDTLRNGLMDVHRKALENISNA
EINSRDRALWIAGLLGLVGLAVLCIGFVTAHGIARRFGAPIEALAKAADRIGEGDYEVTLPISSAAEMNLLTRRFGIMAE
ALRQHQATNVDELLAGQQRLQAVLDSIDDGLLMIDRQGHLEHLNPVAQRQLGWDESRLGHSLGEALGRPELDEQLHLVLR
GGTLERAPEDLAIEIDGESRLLTYSMTPVSHTKGHILGAVMVLHDVTEQRAFERVRSEFVLRASHELRTPVTGMHMAFGL
LQERLHFAPESREADLLNTVTEEMQRLMQLINDLLNFSRYQNGLQKLKLAPCSIETLLQEAKARFEDQAQEQDIVLMLDM
QEPMPRLHADQSQLERVLDNLLDNALRHTPPNGLIRLQARRHGERAIISVEDNGEGIAYGQQGRIFEPFVQVGRKKGGAG
LGLALCKEIVQLHGGRMGVYSRPGQGTQFYMALPL
>Mature_595_residues
MKLAMKLRTRLFLSISALITVALLGLLLGLVSVMQMARTQESLIQHNFAILDLGLKLRQNMGDQLVLMTGSSRNEPELQR
MQKQFEELLEEGSAQDTQQNVRNGFEKTRGDYQRFIATWQQYGNDPRGIRGNSQLSESFDTLRNGLMDVHRKALENISNA
EINSRDRALWIAGLLGLVGLAVLCIGFVTAHGIARRFGAPIEALAKAADRIGEGDYEVTLPISSAAEMNLLTRRFGIMAE
ALRQHQATNVDELLAGQQRLQAVLDSIDDGLLMIDRQGHLEHLNPVAQRQLGWDESRLGHSLGEALGRPELDEQLHLVLR
GGTLERAPEDLAIEIDGESRLLTYSMTPVSHTKGHILGAVMVLHDVTEQRAFERVRSEFVLRASHELRTPVTGMHMAFGL
LQERLHFAPESREADLLNTVTEEMQRLMQLINDLLNFSRYQNGLQKLKLAPCSIETLLQEAKARFEDQAQEQDIVLMLDM
QEPMPRLHADQSQLERVLDNLLDNALRHTPPNGLIRLQARRHGERAIISVEDNGEGIAYGQQGRIFEPFVQVGRKKGGAG
LGLALCKEIVQLHGGRMGVYSRPGQGTQFYMALPL

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=419, Percent_Identity=26.491646778043, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081816, Length=231, Percent_Identity=32.4675324675325, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=30.1652892561983, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1786600, Length=343, Percent_Identity=27.9883381924198, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=31.858407079646, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=31.0077519379845, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=31.924882629108, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=26.9372693726937, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=364, Percent_Identity=26.3736263736264, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1790300, Length=356, Percent_Identity=28.6516853932584, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=32.4200913242009, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=30.0847457627119, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI48994928, Length=272, Percent_Identity=25.3676470588235, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787894, Length=216, Percent_Identity=30.5555555555556, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=202, Percent_Identity=30.1980198019802, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790567, Length=352, Percent_Identity=28.6931818181818, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=30.1724137931034, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790551, Length=218, Percent_Identity=30.7339449541284, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789808, Length=216, Percent_Identity=28.2407407407407, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788279, Length=230, Percent_Identity=25.2173913043478, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66558; Mature: 66558

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAMKLRTRLFLSISALITVALLGLLLGLVSVMQMARTQESLIQHNFAILDLGLKLRQN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
MGDQLVLMTGSSRNEPELQRMQKQFEELLEEGSAQDTQQNVRNGFEKTRGDYQRFIATWQ
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYGNDPRGIRGNSQLSESFDTLRNGLMDVHRKALENISNAEINSRDRALWIAGLLGLVGL
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
AVLCIGFVTAHGIARRFGAPIEALAKAADRIGEGDYEVTLPISSAAEMNLLTRRFGIMAE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
ALRQHQATNVDELLAGQQRLQAVLDSIDDGLLMIDRQGHLEHLNPVAQRQLGWDESRLGH
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHCCHHHHHHCCCCHHHHHH
SLGEALGRPELDEQLHLVLRGGTLERAPEDLAIEIDGESRLLTYSMTPVSHTKGHILGAV
HHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHH
MVLHDVTEQRAFERVRSEFVLRASHELRTPVTGMHMAFGLLQERLHFAPESREADLLNTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
TEEMQRLMQLINDLLNFSRYQNGLQKLKLAPCSIETLLQEAKARFEDQAQEQDIVLMLDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC
QEPMPRLHADQSQLERVLDNLLDNALRHTPPNGLIRLQARRHGERAIISVEDNGEGIAYG
CCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCEEEEC
QQGRIFEPFVQVGRKKGGAGLGLALCKEIVQLHGGRMGVYSRPGQGTQFYMALPL
CCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MKLAMKLRTRLFLSISALITVALLGLLLGLVSVMQMARTQESLIQHNFAILDLGLKLRQN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
MGDQLVLMTGSSRNEPELQRMQKQFEELLEEGSAQDTQQNVRNGFEKTRGDYQRFIATWQ
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYGNDPRGIRGNSQLSESFDTLRNGLMDVHRKALENISNAEINSRDRALWIAGLLGLVGL
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
AVLCIGFVTAHGIARRFGAPIEALAKAADRIGEGDYEVTLPISSAAEMNLLTRRFGIMAE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
ALRQHQATNVDELLAGQQRLQAVLDSIDDGLLMIDRQGHLEHLNPVAQRQLGWDESRLGH
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHCCHHHHHHCCCCHHHHHH
SLGEALGRPELDEQLHLVLRGGTLERAPEDLAIEIDGESRLLTYSMTPVSHTKGHILGAV
HHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHH
MVLHDVTEQRAFERVRSEFVLRASHELRTPVTGMHMAFGLLQERLHFAPESREADLLNTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
TEEMQRLMQLINDLLNFSRYQNGLQKLKLAPCSIETLLQEAKARFEDQAQEQDIVLMLDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC
QEPMPRLHADQSQLERVLDNLLDNALRHTPPNGLIRLQARRHGERAIISVEDNGEGIAYG
CCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCEEEEC
QQGRIFEPFVQVGRKKGGAGLGLALCKEIVQLHGGRMGVYSRPGQGTQFYMALPL
CCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]