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The map label for this gene is recG [H]

Identifier: 66043471

GI number: 66043471

Start: 215460

End: 217535

Strand: Reverse

Name: recG [H]

Synonym: Psyr_0201

Alternate gene names: 66043471

Gene position: 217535-215460 (Counterclockwise)

Preceding gene: 66043472

Following gene: 66043470

Centisome position: 3.57

GC content: 63.73

Gene sequence:

>2076_bases
ATGAGCGAGCTTTCCAGGGTCTCGGTCACGGCGCTCAAGGGTGTCGGCGAAGCGATGGCAGAAAAGCTGGCCAAGGTCGG
CCTGGAAACACTGCAGGACGTGCTGTTCCATCTGCCGCTGCGTTATCAGGATCGCACGCGCATCGTACCGATCGGTGCGC
TGCGTCCCGGTCAGGATGCCGTTATCGAAGGCGTGGTCAGCGGTGCCGATGTGGTGATGGGCAAGCGTCGCAGCCTGCTG
GTGCGGCTGGGCGACGGCACCGGGGTCGTCAGCCTGCGCTTCTACCATTTCAGCAACGCCCAGAAAGAAAGCATGAAGCG
TGGCACGCACCTGCGTTGCTTCGGCGAAGCGCGCCCGGGTGCTTCCGGACTGGAGATCTATCACCCGGAATATCGGGCGA
TTACCGGTGATGAGCCCGCGCCCGTCGAACAGACCCTCACGCCGATCTACCCGACGACCGAAGGCCTGACCCAACAGCGT
CTGCGCCAGCTGTGCCAGCAAAGCCTGGCGATGCTCGGCCCCAAAAGTCTGCCGGACTGGCTGCCTGAAGAGCTGGCCCG
CGATTATCAGCTGGCCCCGCTGGATGATGCGATCCGTTACCTGCATCACCCGCCGGCCGATGCCGACGTGGAGGAGCTGG
CCCTCGGGCATCATTGGGCGCAGCACCGACTGGCTTTCGAAGAACTGCTGACTCACCAGCTTTCCCAGCAACGCCTGCGT
GAAAGCCTGCGGTCACAGCGCGCACCGGCATTGCCCGTTGCGAAAAAACTGCCGAAACAGTTTCTCGCCAACCTCGGCTT
TGCCCCCACCGGCGCGCAGCAGCGTGTCGGCAAGGAAGTCGCCTATGACCTGAGTCAGCCTGAGCCGATGCTGCGGCTGA
TTCAGGGCGACGTAGGGTCGGGCAAGACCGTGGTTGCTGCGCTGGCTGCATTGCAGGCACTGGAAGCGGGTTATCAAGTG
GCGCTGATGGCGCCCACCGAGATTCTCGCCGAGCAGCACTACATCAACTTCCAGCGCTGGCTTGAGCCCCTGGGCGTGGG
TGTGGCATGGCTGGCGGGCAAGCTCAAAGGCAAGGCGCGCGTCGCGTCTCTGGAGCAGATCGCCGGCGGCACACCCATGG
TGGTCGGCACCCATGCGCTGTTTCAGGACGAAGTGCAGTTCAAGAACCTGGCACTGGTGATCATCGACGAGCAGCACCGG
TTCGGCGTTCAGCAACGCCTGGCGCTGCGCAAAAAGGGCGTTGGCGGTCTGATGTGCCCGCATCAGTTGATCATGACCGC
CACACCGATCCCGCGCACGCTGGCCATGAGTGCCTACGCCGACCTGGACACTTCGATCCTCGACGAACTGCCGCCGGGGC
GGACGCCAGTCAATACCGTGCTGGTTGCCGACAGTCGCCGCCTGGAAGTCGTGGAGCGGGTGCGCGCCGCCTGCGCAGAA
GGGCGCCAGGCCTACTGGGTGTGCACGCTGATCGAAGAATCCGAAGAGCTGACCTGCAAGGCCGCTGAAACCACCTACGA
AGAGTTGAGCAGCGCGTTGGGTGACGTGCGCGTCGGGCTGATTCACGGGCGCATGAAGCCTGCAGAAAAGGCCGCGATCA
TGGCCGAGTTCAAGCAAGGTGCGCTGCAATTGTTGGTGGCAACGACGGTCATCGAAGTCGGTGTCGACGTGCCGAACTCC
AGTCTGATGATCATCGAGAACCCCGAGCGCCTCGGCCTGGCGCAATTGCACCAGTTGCGCGGCCGCGTCGGGCGCGGCAG
CGCGGTGAGTCATTGTGTGCTGCTCTACCATCCGCCGCTTTCACAGATCGGACGGCAGCGCCTGGGCATCATGCGCGAAA
CCAACGATGGTTTCGTCATCGCCGAAAAAGACCTTGAACTGCGTGGCCCCGGCGAAATGCTCGGCACCCGACAAACGGGC
CTTCTGCAATTCAAGGTCGCCGACCTGATGCGCGACGCAGACCTGCTACCGGCCGTACGCGACGCGGCTCAGGCCTTGTT
GGAGCGCTGGCCGCAACACGTCAGCCCACTGCTCGACAGGTGGCTGCGTCATGGCCAGCAGTATGGCCAGGTGTGA

Upstream 100 bases:

>100_bases
CAAGCTTCCCGAGACCCAAAGCCATCGAAATCCTCGCTGACTCTGCACGTCTGTGCTCGGTGGCACGTCCGAAAACAGTC
GCTAGCTAGGCAGAACAGAA

Downstream 100 bases:

>100_bases
TGCAGACTATGCTTTGCAAACCGCGTGCGACCCAAATCGAATAACGTGGTTATACTTCAGAAAATGTAGGAATTTGGACA
TAGCTCATGACAGAAGTCGC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MSELSRVSVTALKGVGEAMAEKLAKVGLETLQDVLFHLPLRYQDRTRIVPIGALRPGQDAVIEGVVSGADVVMGKRRSLL
VRLGDGTGVVSLRFYHFSNAQKESMKRGTHLRCFGEARPGASGLEIYHPEYRAITGDEPAPVEQTLTPIYPTTEGLTQQR
LRQLCQQSLAMLGPKSLPDWLPEELARDYQLAPLDDAIRYLHHPPADADVEELALGHHWAQHRLAFEELLTHQLSQQRLR
ESLRSQRAPALPVAKKLPKQFLANLGFAPTGAQQRVGKEVAYDLSQPEPMLRLIQGDVGSGKTVVAALAALQALEAGYQV
ALMAPTEILAEQHYINFQRWLEPLGVGVAWLAGKLKGKARVASLEQIAGGTPMVVGTHALFQDEVQFKNLALVIIDEQHR
FGVQQRLALRKKGVGGLMCPHQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVADSRRLEVVERVRAACAE
GRQAYWVCTLIEESEELTCKAAETTYEELSSALGDVRVGLIHGRMKPAEKAAIMAEFKQGALQLLVATTVIEVGVDVPNS
SLMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPLSQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTG
LLQFKVADLMRDADLLPAVRDAAQALLERWPQHVSPLLDRWLRHGQQYGQV

Sequences:

>Translated_691_residues
MSELSRVSVTALKGVGEAMAEKLAKVGLETLQDVLFHLPLRYQDRTRIVPIGALRPGQDAVIEGVVSGADVVMGKRRSLL
VRLGDGTGVVSLRFYHFSNAQKESMKRGTHLRCFGEARPGASGLEIYHPEYRAITGDEPAPVEQTLTPIYPTTEGLTQQR
LRQLCQQSLAMLGPKSLPDWLPEELARDYQLAPLDDAIRYLHHPPADADVEELALGHHWAQHRLAFEELLTHQLSQQRLR
ESLRSQRAPALPVAKKLPKQFLANLGFAPTGAQQRVGKEVAYDLSQPEPMLRLIQGDVGSGKTVVAALAALQALEAGYQV
ALMAPTEILAEQHYINFQRWLEPLGVGVAWLAGKLKGKARVASLEQIAGGTPMVVGTHALFQDEVQFKNLALVIIDEQHR
FGVQQRLALRKKGVGGLMCPHQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVADSRRLEVVERVRAACAE
GRQAYWVCTLIEESEELTCKAAETTYEELSSALGDVRVGLIHGRMKPAEKAAIMAEFKQGALQLLVATTVIEVGVDVPNS
SLMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPLSQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTG
LLQFKVADLMRDADLLPAVRDAAQALLERWPQHVSPLLDRWLRHGQQYGQV
>Mature_690_residues
SELSRVSVTALKGVGEAMAEKLAKVGLETLQDVLFHLPLRYQDRTRIVPIGALRPGQDAVIEGVVSGADVVMGKRRSLLV
RLGDGTGVVSLRFYHFSNAQKESMKRGTHLRCFGEARPGASGLEIYHPEYRAITGDEPAPVEQTLTPIYPTTEGLTQQRL
RQLCQQSLAMLGPKSLPDWLPEELARDYQLAPLDDAIRYLHHPPADADVEELALGHHWAQHRLAFEELLTHQLSQQRLRE
SLRSQRAPALPVAKKLPKQFLANLGFAPTGAQQRVGKEVAYDLSQPEPMLRLIQGDVGSGKTVVAALAALQALEAGYQVA
LMAPTEILAEQHYINFQRWLEPLGVGVAWLAGKLKGKARVASLEQIAGGTPMVVGTHALFQDEVQFKNLALVIIDEQHRF
GVQQRLALRKKGVGGLMCPHQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVADSRRLEVVERVRAACAEG
RQAYWVCTLIEESEELTCKAAETTYEELSSALGDVRVGLIHGRMKPAEKAAIMAEFKQGALQLLVATTVIEVGVDVPNSS
LMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPLSQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTGL
LQFKVADLMRDADLLPAVRDAAQALLERWPQHVSPLLDRWLRHGQQYGQV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=690, Percent_Identity=57.9710144927536, Blast_Score=769, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=391, Percent_Identity=36.5728900255754, Blast_Score=222, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76045; Mature: 75914

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELSRVSVTALKGVGEAMAEKLAKVGLETLQDVLFHLPLRYQDRTRIVPIGALRPGQDA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHH
VIEGVVSGADVVMGKRRSLLVRLGDGTGVVSLRFYHFSNAQKESMKRGTHLRCFGEARPG
HHHHHHCCHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHCCCEEEEEECCCCC
ASGLEIYHPEYRAITGDEPAPVEQTLTPIYPTTEGLTQQRLRQLCQQSLAMLGPKSLPDW
CCCCEEECCCCEEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
LPEELARDYQLAPLDDAIRYLHHPPADADVEELALGHHWAQHRLAFEELLTHQLSQQRLR
CHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLRSQRAPALPVAKKLPKQFLANLGFAPTGAQQRVGKEVAYDLSQPEPMLRLIQGDVGS
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
GKTVVAALAALQALEAGYQVALMAPTEILAEQHYINFQRWLEPLGVGVAWLAGKLKGKAR
CHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
VASLEQIAGGTPMVVGTHALFQDEVQFKNLALVIIDEQHRFGVQQRLALRKKGVGGLMCP
HHHHHHHCCCCCEEEECHHHHHHHHHHCCEEEEEEECHHHHCHHHHHHHHHCCCCCCCCC
HQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVADSRRLEVVERVRAACAE
HHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
GRQAYWVCTLIEESEELTCKAAETTYEELSSALGDVRVGLIHGRMKPAEKAAIMAEFKQG
CCCEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHH
ALQLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPL
HHHHHHHHHHHHHCCCCCCCCEEEEECCHHCCHHHHHHHHCCCCCCCHHHEEEEEECCCH
SQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTGLLQFKVADLMRDADLLPAVR
HHHHHHHHCCEEECCCCEEEEECCCCCCCCHHHHCCCCCCEEEHHHHHHHHCHHHHHHHH
DAAQALLERWPQHVSPLLDRWLRHGQQYGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SELSRVSVTALKGVGEAMAEKLAKVGLETLQDVLFHLPLRYQDRTRIVPIGALRPGQDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHH
VIEGVVSGADVVMGKRRSLLVRLGDGTGVVSLRFYHFSNAQKESMKRGTHLRCFGEARPG
HHHHHHCCHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHCCCEEEEEECCCCC
ASGLEIYHPEYRAITGDEPAPVEQTLTPIYPTTEGLTQQRLRQLCQQSLAMLGPKSLPDW
CCCCEEECCCCEEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
LPEELARDYQLAPLDDAIRYLHHPPADADVEELALGHHWAQHRLAFEELLTHQLSQQRLR
CHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLRSQRAPALPVAKKLPKQFLANLGFAPTGAQQRVGKEVAYDLSQPEPMLRLIQGDVGS
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
GKTVVAALAALQALEAGYQVALMAPTEILAEQHYINFQRWLEPLGVGVAWLAGKLKGKAR
CHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
VASLEQIAGGTPMVVGTHALFQDEVQFKNLALVIIDEQHRFGVQQRLALRKKGVGGLMCP
HHHHHHHCCCCCEEEECHHHHHHHHHHCCEEEEEEECHHHHCHHHHHHHHHCCCCCCCCC
HQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVADSRRLEVVERVRAACAE
HHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
GRQAYWVCTLIEESEELTCKAAETTYEELSSALGDVRVGLIHGRMKPAEKAAIMAEFKQG
CCCEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHH
ALQLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGSAVSHCVLLYHPPL
HHHHHHHHHHHHHCCCCCCCCEEEEECCHHCCHHHHHHHHCCCCCCCHHHEEEEEECCCH
SQIGRQRLGIMRETNDGFVIAEKDLELRGPGEMLGTRQTGLLQFKVADLMRDADLLPAVR
HHHHHHHHCCEEECCCCEEEEECCCCCCCCHHHHCCCCCCEEEHHHHHHHHCHHHHHHHH
DAAQALLERWPQHVSPLLDRWLRHGQQYGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]