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The map label for this gene is hlyB [H]

Identifier: 66043413

GI number: 66043413

Start: 155026

End: 156546

Strand: Reverse

Name: hlyB [H]

Synonym: Psyr_0143

Alternate gene names: 66043413

Gene position: 156546-155026 (Counterclockwise)

Preceding gene: 66043414

Following gene: 66043403

Centisome position: 2.57

GC content: 62.66

Gene sequence:

>1521_bases
ATGGATTTCAAAAGGATGTGTTCGATGCCCGTAGCCCCTCGTTTCCTGGACCATTACCGCAAGGCCGACCGGATCATGCT
GGGTCTGATCTGGCTGTTGTTCATCTACGCGCTCGGGTTGGCGTTCTGGTTCGACACCTTCACCCAGGCCGTCGTCGTCG
GTGGTGGCACCGCGGTGGTGCTGACCGGGCTGTATCGGGCCATCGGCGGCACCCGATTGATGCGTTGCTGTTTCGGTGTA
GGCCTGATGGTCATGACCGCGCTGCACATCAATCAGACCCACGGGCAGGTCGAGATACATTTCGGCATCTTTGTCCTGCT
CGCTGTGCTGACCTTCTACCGCGACTGGCTGCCGATTCTGGTCGCTGCCGTCACCATCGCGCTCCACCACATCGGTTTCC
ATGCCCTGCAGCATTCCGGCTTCCCGGTGTACGTCATGCACCACGGCTTCGGCTGGAGCATGGTGCTTGTGCATGCGGTG
TATGTGGTGGTTGAAAGCGCGATTCTGGTGTACCTGGCGGTGCAGAATCAGGCCGAGGCGGTCGAGAATCAGGACATGCT
GGACCGGATGCTGGCCACCACCAACCAGTTCTCTACCGATGGCCAGTCCAGCCAGCAGTCGGGCAAACATGTCTCGCTGG
CGCAGCGTTTCGAACAGTTCCTGGCGCAGATCACCGGCCTGGTCGATGGCGTAGTGCGTGACACTCGCGGGCTTGGCGAG
CTGGGTCATGACCTCGCCAAGGCCAGCGGTACGCTGGAAACCGGTGCACAGCATCAGCTCAGTGAAATCGCCCGCATGAC
CGGCGCGATGCAGCGCATGGGCGATGCCATGAACGATATCTCCAGCCACGTCGCGCAAGCCGTGCAGCGGGCCGGTGACG
CCAGCGATCAGGTCGCTCATGGGCGCGACAGTGTCGACCGCGCGCAGAGCGAAATCACTCAGCTTGCCGCACGCATCACG
ACCACCGATGAAACCGTGCAGGCCCTGGCCAACCAGTCAGAACAGATTGGCAAGGTGCTGGACGTGATCGGCAGCATTGC
CGAGCAGACCAACCTGCTGGCCCTCAACGCTGCAATCGAAGCCGCCCGCGCCGGTGAGCAGGGCCGAGGCTTTGCGGTGG
TGGCCGATGAGGTACGCAACCTGGCGCAGCGCACAGCAGCCTCGACCAAGGAAATCCAGACCATCATCGAAGACCTGCAA
AAAGGCAGCCGTCAGGCCGCTACGGCCATGAGCGACAGCCTGCAGGGTGTCGGGCGTTGTGTCGAGGACAGCCAGCGGGC
TTCGCAATCCCTGCGCGCCGTCGGCGAAGGCATCGGCCATATCACCCAGCTCAACGGCCTGATTGCCACGACGACCGAAC
AGCAGTCCGCCGTCAGCCGGGAAATGGCCGATCAGTTGCGCTCGGTGCAGACCATCGCCGAACACACCGCCGCCAATATC
GGTGTGCTGGCGACCAGCAGCCAGAGCCTGTCGCCACTGGCCATTCGCCTGGAAGCGCTGGGCAAGAGCTTTCACGCGTA
G

Upstream 100 bases:

>100_bases
AGGTATGTCTGAAATTCTGGCATAGCGCTACTATCCGGACGGCACTTTGGCCGGGCTTTTGCTCGTGCAGATTTGAAAAC
CGGCAGGAGCTCCTGTCGCC

Downstream 100 bases:

>100_bases
TTTTCGGGCTCAGGCGAACACCAGCCCCGACGAACGCAGCAGTTCCTGAGTGTAGGCCTGCTGCGGTGCGGCGAAGATCT
CGCGGGACGGACCCTGCTCG

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDFKRMCSMPVAPRFLDHYRKADRIMLGLIWLLFIYALGLAFWFDTFTQAVVVGGGTAVVLTGLYRAIGGTRLMRCCFGV
GLMVMTALHINQTHGQVEIHFGIFVLLAVLTFYRDWLPILVAAVTIALHHIGFHALQHSGFPVYVMHHGFGWSMVLVHAV
YVVVESAILVYLAVQNQAEAVENQDMLDRMLATTNQFSTDGQSSQQSGKHVSLAQRFEQFLAQITGLVDGVVRDTRGLGE
LGHDLAKASGTLETGAQHQLSEIARMTGAMQRMGDAMNDISSHVAQAVQRAGDASDQVAHGRDSVDRAQSEITQLAARIT
TTDETVQALANQSEQIGKVLDVIGSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAQRTAASTKEIQTIIEDLQ
KGSRQAATAMSDSLQGVGRCVEDSQRASQSLRAVGEGIGHITQLNGLIATTTEQQSAVSREMADQLRSVQTIAEHTAANI
GVLATSSQSLSPLAIRLEALGKSFHA

Sequences:

>Translated_506_residues
MDFKRMCSMPVAPRFLDHYRKADRIMLGLIWLLFIYALGLAFWFDTFTQAVVVGGGTAVVLTGLYRAIGGTRLMRCCFGV
GLMVMTALHINQTHGQVEIHFGIFVLLAVLTFYRDWLPILVAAVTIALHHIGFHALQHSGFPVYVMHHGFGWSMVLVHAV
YVVVESAILVYLAVQNQAEAVENQDMLDRMLATTNQFSTDGQSSQQSGKHVSLAQRFEQFLAQITGLVDGVVRDTRGLGE
LGHDLAKASGTLETGAQHQLSEIARMTGAMQRMGDAMNDISSHVAQAVQRAGDASDQVAHGRDSVDRAQSEITQLAARIT
TTDETVQALANQSEQIGKVLDVIGSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAQRTAASTKEIQTIIEDLQ
KGSRQAATAMSDSLQGVGRCVEDSQRASQSLRAVGEGIGHITQLNGLIATTTEQQSAVSREMADQLRSVQTIAEHTAANI
GVLATSSQSLSPLAIRLEALGKSFHA
>Mature_506_residues
MDFKRMCSMPVAPRFLDHYRKADRIMLGLIWLLFIYALGLAFWFDTFTQAVVVGGGTAVVLTGLYRAIGGTRLMRCCFGV
GLMVMTALHINQTHGQVEIHFGIFVLLAVLTFYRDWLPILVAAVTIALHHIGFHALQHSGFPVYVMHHGFGWSMVLVHAV
YVVVESAILVYLAVQNQAEAVENQDMLDRMLATTNQFSTDGQSSQQSGKHVSLAQRFEQFLAQITGLVDGVVRDTRGLGE
LGHDLAKASGTLETGAQHQLSEIARMTGAMQRMGDAMNDISSHVAQAVQRAGDASDQVAHGRDSVDRAQSEITQLAARIT
TTDETVQALANQSEQIGKVLDVIGSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAQRTAASTKEIQTIIEDLQ
KGSRQAATAMSDSLQGVGRCVEDSQRASQSLRAVGEGIGHITQLNGLIATTTEQQSAVSREMADQLRSVQTIAEHTAANI
GVLATSSQSLSPLAIRLEALGKSFHA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=272, Percent_Identity=30.1470588235294, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788195, Length=262, Percent_Identity=32.0610687022901, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI2367378, Length=213, Percent_Identity=32.3943661971831, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787690, Length=262, Percent_Identity=35.1145038167939, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=31.7073170731707, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54571; Mature: 54571

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKRMCSMPVAPRFLDHYRKADRIMLGLIWLLFIYALGLAFWFDTFTQAVVVGGGTAVV
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LTGLYRAIGGTRLMRCCFGVGLMVMTALHINQTHGQVEIHFGIFVLLAVLTFYRDWLPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
VAAVTIALHHIGFHALQHSGFPVYVMHHGFGWSMVLVHAVYVVVESAILVYLAVQNQAEA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VENQDMLDRMLATTNQFSTDGQSSQQSGKHVSLAQRFEQFLAQITGLVDGVVRDTRGLGE
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHDLAKASGTLETGAQHQLSEIARMTGAMQRMGDAMNDISSHVAQAVQRAGDASDQVAH
HHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHC
GRDSVDRAQSEITQLAARITTTDETVQALANQSEQIGKVLDVIGSIAEQTNLLALNAAIE
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARAGEQGRGFAVVADEVRNLAQRTAASTKEIQTIIEDLQKGSRQAATAMSDSLQGVGRC
HHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VEDSQRASQSLRAVGEGIGHITQLNGLIATTTEQQSAVSREMADQLRSVQTIAEHTAANI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVLATSSQSLSPLAIRLEALGKSFHA
CEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure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CEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]