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The map label for this gene is yrhP [H]

Identifier: 66043387

GI number: 66043387

Start: 126577

End: 127209

Strand: Reverse

Name: yrhP [H]

Synonym: Psyr_0116

Alternate gene names: 66043387

Gene position: 127209-126577 (Counterclockwise)

Preceding gene: 66043388

Following gene: 66043384

Centisome position: 2.09

GC content: 53.4

Gene sequence:

>633_bases
ATGAATGTACATCTGTATCTTTCGTTTATCCTCACGAGCCTCATCGTTCTTGTCGTTCCAGGGCCAAGTTTTGCTTATGC
AATCGCCGTCGGAATGCGCAGCTCCCGACAAGTGATCTTGCGCAACGCACTTGGCATGGCGCTCGGTGGGCTTACCATCA
CCATGGCGCTCGCGTTCGGAGTAGCCCAGCTCTTTGCAGCCTATCCGACCGCATTCGTTGCTCTGAAGTTTATCGGGTGT
ACATACCTTGTCGCGCTGGGGATTCGCACATTCTTTACCCGCCCCGAGCCCAAACACGCGTGCAAAATAGAAACGTCAGC
AACACCGCTTTTACAAGGGTTCATAGTCGAAACCGCGAATCCAAAGGCTATCCTGTTTTACGTTTCGCTCGTTCCTCAGT
TCGCTGATCCGGAGCTCGGTCACATGGAAGCCCAATTGCTGATTCTTGGGGCCACCTTCGTTGCTCTACAGGTCACATGG
GACATCGCTTTGATGCTTGGAGTACATCGGCTCGGAGCAATTGCAGGAGGCCTCATGTCCACGAAGTCCCAGCGAATCAT
TAATCGAATAAGCGGGACCACGTTTATCGTGCTGGGCCTGGCCTTACTCACTCAGGAGCGACCCGTTAGCTGA

Upstream 100 bases:

>100_bases
CTTCGCCAAGGCATCGAACGCTACGCCGATGCCTGAGTAAAAAAGCAAATACGGCCCGCATCCTGCGGGCCGAACCGTCG
ACGCATCGAAAACTTACTCA

Downstream 100 bases:

>100_bases
CCGGTAATGTGCTTCCTATAACACCCCGTAAGCGTGGCTTCAGTAACAGGGTCGGAGTCACGTTCGACTCTACGCGCTGT
AAAGGAGCATTCCGATCAGG

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNVHLYLSFILTSLIVLVVPGPSFAYAIAVGMRSSRQVILRNALGMALGGLTITMALAFGVAQLFAAYPTAFVALKFIGC
TYLVALGIRTFFTRPEPKHACKIETSATPLLQGFIVETANPKAILFYVSLVPQFADPELGHMEAQLLILGATFVALQVTW
DIALMLGVHRLGAIAGGLMSTKSQRIINRISGTTFIVLGLALLTQERPVS

Sequences:

>Translated_210_residues
MNVHLYLSFILTSLIVLVVPGPSFAYAIAVGMRSSRQVILRNALGMALGGLTITMALAFGVAQLFAAYPTAFVALKFIGC
TYLVALGIRTFFTRPEPKHACKIETSATPLLQGFIVETANPKAILFYVSLVPQFADPELGHMEAQLLILGATFVALQVTW
DIALMLGVHRLGAIAGGLMSTKSQRIINRISGTTFIVLGLALLTQERPVS
>Mature_210_residues
MNVHLYLSFILTSLIVLVVPGPSFAYAIAVGMRSSRQVILRNALGMALGGLTITMALAFGVAQLFAAYPTAFVALKFIGC
TYLVALGIRTFFTRPEPKHACKIETSATPLLQGFIVETANPKAILFYVSLVPQFADPELGHMEAQLLILGATFVALQVTW
DIALMLGVHRLGAIAGGLMSTKSQRIINRISGTTFIVLGLALLTQERPVS

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=210, Percent_Identity=26.1904761904762, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22550; Mature: 22550

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVHLYLSFILTSLIVLVVPGPSFAYAIAVGMRSSRQVILRNALGMALGGLTITMALAFG
CCEEEEHHHHHHHHHEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VAQLFAAYPTAFVALKFIGCTYLVALGIRTFFTRPEPKHACKIETSATPLLQGFIVETAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHEEECCC
PKAILFYVSLVPQFADPELGHMEAQLLILGATFVALQVTWDIALMLGVHRLGAIAGGLMS
CCEEEEEEECCCCCCCCCCCCHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKSQRIINRISGTTFIVLGLALLTQERPVS
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNVHLYLSFILTSLIVLVVPGPSFAYAIAVGMRSSRQVILRNALGMALGGLTITMALAFG
CCEEEEHHHHHHHHHEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VAQLFAAYPTAFVALKFIGCTYLVALGIRTFFTRPEPKHACKIETSATPLLQGFIVETAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHEEECCC
PKAILFYVSLVPQFADPELGHMEAQLLILGATFVALQVTWDIALMLGVHRLGAIAGGLMS
CCEEEEEEECCCCCCCCCCCCHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKSQRIINRISGTTFIVLGLALLTQERPVS
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]