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The map label for this gene is zraR [H]

Identifier: 66043348

GI number: 66043348

Start: 82724

End: 84043

Strand: Reverse

Name: zraR [H]

Synonym: Psyr_0077

Alternate gene names: 66043348

Gene position: 84043-82724 (Counterclockwise)

Preceding gene: 66043352

Following gene: 66043345

Centisome position: 1.38

GC content: 64.09

Gene sequence:

>1320_bases
ATGAACCTCATCGCCACCGATTTTCCCGGCAGTCGCATGCAGTCGCTGGTGTCATACCTCGAACACGATCTGCGACCGAC
CATCGTGCTCGACACCGACTACAACATCATTGCCGCCAACACCGCCTACCAGCGCCAGTTCGGCGTCGAAGGCACGCCGC
ATGTGGGCGAGAAGTGTTATCGGGTGTCGCATCAGTTTGCGGTGCCGTGCGATCAGGCCGGTGAGCACTGCCCGATGCGC
AAGGCCCATGAAACACGGCTCCCGGAGCGTCTGCTGCACATTCATCACACGCCGCGCGGCCCCGAGCATGTGGATGTGGA
GCTGCGGCCGATTCTCGACGATCAGGGTGAGGTCATCGCCTATGTCGAGCGGCTGAGCTCGGTGGCGGTGGCCTCCGTCC
AGCCGCAGCAACATGGGCTGGTAGGGCGCTCGGCGGCGTTCAAGGAAGTGCTGAGCGCTCTGCAACGTGCGGCGCCCGCA
CAGATTCCGGTGCTGCTGCAGGGCGAGTCGGGCACCGGCAAGGAATTGTTCGCGCGCGCACTGCACGCCAGCAGCGCCAG
GTCCGCCGGACCGCTGGTGGTGGTCGACTGCACCGGGCTTACCGAAACCCTGCTGGAAAGCGAGCTGTTCGGCTATGAGA
AGGGCGCGTTCACTGGCGCATTGCAGCGCAAGACCGGTCTGGCCGAAGCGGCTCATGGCGGGACGTTGTTCCTTGATGAG
ATCGGTGAAGTGCCGCTGGCCATGCAGGTCAAGCTGTTGCGGCTGATCGAATCGGGCAGTTTTCGTCCGGTGGGCAGCCT
GCGCACGGTGCACTCGGATTTTCGGCTGGTGGTGGCCACCCATAAACCGCTCAGGGAGATGGTCGCCGACGGCAGCTTTC
GTCAGGATTTGTTCTACCGCATCAGCGCCTTTCCGATTCGCCTGCCGGCCCTGCGCGAACGCAGCGACGACCTGCCGCTG
CTGATCGACAGTCTGCTGCAACGCATCGCGCCCGGCGCCGCTCCGCGTGTCGACGCCGAGGCCATGAAGCTGCTGAGTTT
GTACAGTTACCCCGGCAACATTCGCGAGCTGCGCAACATACTCGAGCGAGCCCGTTTATTTACCGACGACGGCGTGATTC
GCGTGCAGGATTTGCCCGCCGAAGTACGCGGGCAGGGCGAAGCGGTTGGCGTGACGTACCGCCAGCAGGACGACGGCCTG
GAAAAACTCGCCCATGCGCTGCGAGTGTTCAACGGCTCGCGCAGCGAACTGGCCAGAGAACTGGGGCTGAGCGAACGCAC
CCTGTACCGACGTTTGCGTGCCCTGGGGATTCCGCGCTGA

Upstream 100 bases:

>100_bases
CACAGGTCGCTGACTGCCACATTCTGGCAGTCATTTGGCAGTCCGCGGCACAAGCTGGCAGGCGAATGGGTTAAGCTGCG
CCCAGCCCACAGGAGCACCC

Downstream 100 bases:

>100_bases
CGCACGGACGCTATGACGCAGAGCGTCACGAACGGCATTCCCACGCTGGAGCATGCGGAACGATAACCTCAACTATCGTG
CGGCGCTCCGCGTCGCATGC

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNLIATDFPGSRMQSLVSYLEHDLRPTIVLDTDYNIIAANTAYQRQFGVEGTPHVGEKCYRVSHQFAVPCDQAGEHCPMR
KAHETRLPERLLHIHHTPRGPEHVDVELRPILDDQGEVIAYVERLSSVAVASVQPQQHGLVGRSAAFKEVLSALQRAAPA
QIPVLLQGESGTGKELFARALHASSARSAGPLVVVDCTGLTETLLESELFGYEKGAFTGALQRKTGLAEAAHGGTLFLDE
IGEVPLAMQVKLLRLIESGSFRPVGSLRTVHSDFRLVVATHKPLREMVADGSFRQDLFYRISAFPIRLPALRERSDDLPL
LIDSLLQRIAPGAAPRVDAEAMKLLSLYSYPGNIRELRNILERARLFTDDGVIRVQDLPAEVRGQGEAVGVTYRQQDDGL
EKLAHALRVFNGSRSELARELGLSERTLYRRLRALGIPR

Sequences:

>Translated_439_residues
MNLIATDFPGSRMQSLVSYLEHDLRPTIVLDTDYNIIAANTAYQRQFGVEGTPHVGEKCYRVSHQFAVPCDQAGEHCPMR
KAHETRLPERLLHIHHTPRGPEHVDVELRPILDDQGEVIAYVERLSSVAVASVQPQQHGLVGRSAAFKEVLSALQRAAPA
QIPVLLQGESGTGKELFARALHASSARSAGPLVVVDCTGLTETLLESELFGYEKGAFTGALQRKTGLAEAAHGGTLFLDE
IGEVPLAMQVKLLRLIESGSFRPVGSLRTVHSDFRLVVATHKPLREMVADGSFRQDLFYRISAFPIRLPALRERSDDLPL
LIDSLLQRIAPGAAPRVDAEAMKLLSLYSYPGNIRELRNILERARLFTDDGVIRVQDLPAEVRGQGEAVGVTYRQQDDGL
EKLAHALRVFNGSRSELARELGLSERTLYRRLRALGIPR
>Mature_439_residues
MNLIATDFPGSRMQSLVSYLEHDLRPTIVLDTDYNIIAANTAYQRQFGVEGTPHVGEKCYRVSHQFAVPCDQAGEHCPMR
KAHETRLPERLLHIHHTPRGPEHVDVELRPILDDQGEVIAYVERLSSVAVASVQPQQHGLVGRSAAFKEVLSALQRAAPA
QIPVLLQGESGTGKELFARALHASSARSAGPLVVVDCTGLTETLLESELFGYEKGAFTGALQRKTGLAEAAHGGTLFLDE
IGEVPLAMQVKLLRLIESGSFRPVGSLRTVHSDFRLVVATHKPLREMVADGSFRQDLFYRISAFPIRLPALRERSDDLPL
LIDSLLQRIAPGAAPRVDAEAMKLLSLYSYPGNIRELRNILERARLFTDDGVIRVQDLPAEVRGQGEAVGVTYRQQDDGL
EKLAHALRVFNGSRSELARELGLSERTLYRRLRALGIPR

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=307, Percent_Identity=45.2768729641694, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1788550, Length=320, Percent_Identity=40.625, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1789087, Length=332, Percent_Identity=39.7590361445783, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1788905, Length=313, Percent_Identity=39.6166134185303, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789233, Length=332, Percent_Identity=40.3614457831325, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI87082117, Length=232, Percent_Identity=45.2586206896552, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1790299, Length=366, Percent_Identity=36.0655737704918, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI87082152, Length=232, Percent_Identity=45.6896551724138, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI1786524, Length=318, Percent_Identity=40.251572327044, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI87081872, Length=232, Percent_Identity=44.3965517241379, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1787583, Length=328, Percent_Identity=35.3658536585366, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789828, Length=400, Percent_Identity=31.5, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87081858, Length=378, Percent_Identity=28.042328042328, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48501; Mature: 48501

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIATDFPGSRMQSLVSYLEHDLRPTIVLDTDYNIIAANTAYQRQFGVEGTPHVGEKCY
CCCEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHCCCCCCCCHHHHHH
RVSHQFAVPCDQAGEHCPMRKAHETRLPERLLHIHHTPRGPEHVDVELRPILDDQGEVIA
HHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHH
YVERLSSVAVASVQPQQHGLVGRSAAFKEVLSALQRAAPAQIPVLLQGESGTGKELFARA
HHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHH
LHASSARSAGPLVVVDCTGLTETLLESELFGYEKGAFTGALQRKTGLAEAAHGGTLFLDE
HHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHCCCCEEEHHH
IGEVPLAMQVKLLRLIESGSFRPVGSLRTVHSDFRLVVATHKPLREMVADGSFRQDLFYR
HCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCHHHHHHHCCCCHHHHHHHH
ISAFPIRLPALRERSDDLPLLIDSLLQRIAPGAAPRVDAEAMKLLSLYSYPGNIRELRNI
HHHCCEECCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
LERARLFTDDGVIRVQDLPAEVRGQGEAVGVTYRQQDDGLEKLAHALRVFNGSRSELARE
HHHHHHCCCCCEEEEECCCHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHH
LGLSERTLYRRLRALGIPR
HCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLIATDFPGSRMQSLVSYLEHDLRPTIVLDTDYNIIAANTAYQRQFGVEGTPHVGEKCY
CCCEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHCCCCCCCCHHHHHH
RVSHQFAVPCDQAGEHCPMRKAHETRLPERLLHIHHTPRGPEHVDVELRPILDDQGEVIA
HHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHH
YVERLSSVAVASVQPQQHGLVGRSAAFKEVLSALQRAAPAQIPVLLQGESGTGKELFARA
HHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHH
LHASSARSAGPLVVVDCTGLTETLLESELFGYEKGAFTGALQRKTGLAEAAHGGTLFLDE
HHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHCCCCEEEHHH
IGEVPLAMQVKLLRLIESGSFRPVGSLRTVHSDFRLVVATHKPLREMVADGSFRQDLFYR
HCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCHHHHHHHCCCCHHHHHHHH
ISAFPIRLPALRERSDDLPLLIDSLLQRIAPGAAPRVDAEAMKLLSLYSYPGNIRELRNI
HHHCCEECCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
LERARLFTDDGVIRVQDLPAEVRGQGEAVGVTYRQQDDGLEKLAHALRVFNGSRSELARE
HHHHHHCCCCCEEEEECCCHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHH
LGLSERTLYRRLRALGIPR
HCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]