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The map label for this gene is lytS [H]

Identifier: 66043335

GI number: 66043335

Start: 63388

End: 64470

Strand: Reverse

Name: lytS [H]

Synonym: Psyr_0064

Alternate gene names: 66043335

Gene position: 64470-63388 (Counterclockwise)

Preceding gene: 66043338

Following gene: 66043334

Centisome position: 1.06

GC content: 58.54

Gene sequence:

>1083_bases
ATGCGAATCGAACCTGTGAAACACGACGCCCGGCCCGCGCCCGGCAAAGACTTTTTCCTCCCTGAACTGTGCCTGCCGCA
GGCATTGCTGGTGCTCGTCGTGCTGGCGGAGCTGCTGGTGCTGGTTCTGGTGCTGGTGGAACCGATGCGCAGCGGCTTCG
ACTGGGTACGCCTGGCGTTGATGTCGCTGTTCGTGCAATGGATCGTGCTACTGTCCGCGGCGCTGCTGTGCGGCTTGCGG
CCCTGGCTGGCGCGATTGACGCCGGGGCTGGCAGGCATGCTCAGTTGCCTTCTGGTGGTCGGCCTGACGCTGTTGTGCAC
AGCCGTCACCGATGTCTGTCAGCTTACCGGGCGGATTTCGGTCAGCGGCATGGTCGAGCGTTATCTGCGCTACTCGACGA
TTGCCCTGATCATGTCGGCCCTGATGCTGCGCTATTTCTATCTGCAGAGTCAGTGGCGCAAGCAGCAACAGGGCGAACTG
CGCGCCAGAATCGAATCGCTGCAAGCGCGCATCCGCCCGCATTTCCTCTTCAACACACTCAACAGTATCGCCAGTCTGGT
GGCCAGCAACCCGGTCAAGGCCGAGCAGGCGGTGCTCGATCTTTCGGACCTGTTTCGCGCCAGTCTGGCCAAGCCGGGCA
GCCTGGTGACATGGGGTGAAGAGCTGGCATTGGCAAAACGATATTTATCGATTGAGCAATATCGTCTTGGCGAGCGTCTA
CAGTTGGACTGGAGGGTGAGCGCAATTCCCGATGACTTGCCAATCCCCCAGCTAACCTTGCAGCCATTACTTGAAAACGC
TTTGATTTATGGCATTGCTCCGCGGGTCGAAGGGGGCGTTGTAACAGTCGAAGCGAACTATGAAGGGGGAGAGTTCATAT
TGAGCGTCAGCAATCCCTATGAAGAAGTTGCCAATCGGCAGACTTCCAACGGTACTCAGCAAGCTCTGACGAATATAGGC
GCACGAATTGCGGCACTTTTTGGCCCGCACGCCAGTCTGAGCGTGGAGCGCCGTGACGGTCGTCACTACACCTGTCTACG
CTATCCTTGTGCGAGACTCACGCAGGAAGCCAGAGCTATATGA

Upstream 100 bases:

>100_bases
CCGATACCTGGCACAAGAACGAACGCGATGATAACAGGGTTGATGCATATTTATCCCCGGACAGCTTGCCGCTGACGAGG
CCAGGGCAGAGACTGGAGTC

Downstream 100 bases:

>100_bases
ATGTCCTGATCGTTGATGACGAACCCCTGGCCCGCGAGCGATTGAGCCGCATGGTCAATGAAATCGAGGGTTATCGAGTA
CTGGAACCCAGCGCGTCCAA

Product: histidine kinase internal region

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRIEPVKHDARPAPGKDFFLPELCLPQALLVLVVLAELLVLVLVLVEPMRSGFDWVRLALMSLFVQWIVLLSAALLCGLR
PWLARLTPGLAGMLSCLLVVGLTLLCTAVTDVCQLTGRISVSGMVERYLRYSTIALIMSALMLRYFYLQSQWRKQQQGEL
RARIESLQARIRPHFLFNTLNSIASLVASNPVKAEQAVLDLSDLFRASLAKPGSLVTWGEELALAKRYLSIEQYRLGERL
QLDWRVSAIPDDLPIPQLTLQPLLENALIYGIAPRVEGGVVTVEANYEGGEFILSVSNPYEEVANRQTSNGTQQALTNIG
ARIAALFGPHASLSVERRDGRHYTCLRYPCARLTQEARAI

Sequences:

>Translated_360_residues
MRIEPVKHDARPAPGKDFFLPELCLPQALLVLVVLAELLVLVLVLVEPMRSGFDWVRLALMSLFVQWIVLLSAALLCGLR
PWLARLTPGLAGMLSCLLVVGLTLLCTAVTDVCQLTGRISVSGMVERYLRYSTIALIMSALMLRYFYLQSQWRKQQQGEL
RARIESLQARIRPHFLFNTLNSIASLVASNPVKAEQAVLDLSDLFRASLAKPGSLVTWGEELALAKRYLSIEQYRLGERL
QLDWRVSAIPDDLPIPQLTLQPLLENALIYGIAPRVEGGVVTVEANYEGGEFILSVSNPYEEVANRQTSNGTQQALTNIG
ARIAALFGPHASLSVERRDGRHYTCLRYPCARLTQEARAI
>Mature_360_residues
MRIEPVKHDARPAPGKDFFLPELCLPQALLVLVVLAELLVLVLVLVEPMRSGFDWVRLALMSLFVQWIVLLSAALLCGLR
PWLARLTPGLAGMLSCLLVVGLTLLCTAVTDVCQLTGRISVSGMVERYLRYSTIALIMSALMLRYFYLQSQWRKQQQGEL
RARIESLQARIRPHFLFNTLNSIASLVASNPVKAEQAVLDLSDLFRASLAKPGSLVTWGEELALAKRYLSIEQYRLGERL
QLDWRVSAIPDDLPIPQLTLQPLLENALIYGIAPRVEGGVVTVEANYEGGEFILSVSNPYEEVANRQTSNGTQQALTNIG
ARIAALFGPHASLSVERRDGRHYTCLRYPCARLTQEARAI

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=194, Percent_Identity=31.9587628865979, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788723, Length=186, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40064; Mature: 40064

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEPVKHDARPAPGKDFFLPELCLPQALLVLVVLAELLVLVLVLVEPMRSGFDWVRLAL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MSLFVQWIVLLSAALLCGLRPWLARLTPGLAGMLSCLLVVGLTLLCTAVTDVCQLTGRIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VSGMVERYLRYSTIALIMSALMLRYFYLQSQWRKQQQGELRARIESLQARIRPHFLFNTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSIASLVASNPVKAEQAVLDLSDLFRASLAKPGSLVTWGEELALAKRYLSIEQYRLGERL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHCCCCE
QLDWRVSAIPDDLPIPQLTLQPLLENALIYGIAPRVEGGVVTVEANYEGGEFILSVSNPY
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCHH
EEVANRQTSNGTQQALTNIGARIAALFGPHASLSVERRDGRHYTCLRYPCARLTQEARAI
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MRIEPVKHDARPAPGKDFFLPELCLPQALLVLVVLAELLVLVLVLVEPMRSGFDWVRLAL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MSLFVQWIVLLSAALLCGLRPWLARLTPGLAGMLSCLLVVGLTLLCTAVTDVCQLTGRIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VSGMVERYLRYSTIALIMSALMLRYFYLQSQWRKQQQGELRARIESLQARIRPHFLFNTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSIASLVASNPVKAEQAVLDLSDLFRASLAKPGSLVTWGEELALAKRYLSIEQYRLGERL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHCCCCE
QLDWRVSAIPDDLPIPQLTLQPLLENALIYGIAPRVEGGVVTVEANYEGGEFILSVSNPY
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCHH
EEVANRQTSNGTQQALTNIGARIAALFGPHASLSVERRDGRHYTCLRYPCARLTQEARAI
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA