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The map label for this gene is algR [H]

Identifier: 66043334

GI number: 66043334

Start: 62645

End: 63391

Strand: Reverse

Name: algR [H]

Synonym: Psyr_0063

Alternate gene names: 66043334

Gene position: 63391-62645 (Counterclockwise)

Preceding gene: 66043335

Following gene: 66043333

Centisome position: 1.04

GC content: 61.85

Gene sequence:

>747_bases
ATGAATGTCCTGATCGTTGATGACGAACCCCTGGCCCGCGAGCGATTGAGCCGCATGGTCAATGAAATCGAGGGTTATCG
AGTACTGGAACCCAGCGCGTCCAATGGCGAAGAAGCCTTGGCGCTGATCGAGGCCCACAAACCGGACGTAGTGCTGCTCG
ATATCCGCATGCCGGGCCTCGATGGCCTCCAGGTCGCAGCGCGGCTGTGCGAGCGGGAAGCACCGCCCGCAGTGGTCTTT
TGCACAGCCCATGATGAGTTCGCCCTGGAAGCTTTCCAGGTCAGTGCGGTGGGCTATCTGGTCAAGCCCGTGCGTTCCGA
GCACCTTGTCGAAGCGTTGCGCAAAGCCGAGCGGCCGAACCGTGTGCAACTGGCGGCGTTGACCCGCCCGGCTGCCGAAA
GCGGATCAGGGCCACGCAGCCATATCAGCGCGCGTACCCGCAAAGGCATCGAGCTGATTCCGCTGGATCAGGTGATCTAC
TTTATCGCCGATCACAAGTACGTGACCTTGCGCCACGAGGGCGGCGAAGTGCTGCTGGACGAACCGCTCAAGGCACTGGA
AGACGAATTCGGTGACCGTTTCGTGCGCATCCACCGCAATGCGCTGGTGGCCCGCGAGCGAATAGAACGGTTGCAGCGCA
CCCCGCTGGGGCATTTCCAGCTGTTCCTCAGAGGCCTCAATGGCGATGCGTTGATCGTCAGCCGCCGCCACGTCGCCGGT
GTCCGCAAAATGATGCAGCAGCTCTAG

Upstream 100 bases:

>100_bases
TTGGCCCGCACGCCAGTCTGAGCGTGGAGCGCCGTGACGGTCGTCACTACACCTGTCTACGCTATCCTTGTGCGAGACTC
ACGCAGGAAGCCAGAGCTAT

Downstream 100 bases:

>100_bases
CGCTTCGCCGCTCTGGAGCCTCTGCGCGCAGGCCGATTCATGGAACGGGGGGCAATCCCGGATTCATGTGTTTTTCGGCT
GGCCCGCGGGCAGCCTTCCT

Product: response regulator receiver:LytTr DNA-binding region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNVLIVDDEPLARERLSRMVNEIEGYRVLEPSASNGEEALALIEAHKPDVVLLDIRMPGLDGLQVAARLCEREAPPAVVF
CTAHDEFALEAFQVSAVGYLVKPVRSEHLVEALRKAERPNRVQLAALTRPAAESGSGPRSHISARTRKGIELIPLDQVIY
FIADHKYVTLRHEGGEVLLDEPLKALEDEFGDRFVRIHRNALVARERIERLQRTPLGHFQLFLRGLNGDALIVSRRHVAG
VRKMMQQL

Sequences:

>Translated_248_residues
MNVLIVDDEPLARERLSRMVNEIEGYRVLEPSASNGEEALALIEAHKPDVVLLDIRMPGLDGLQVAARLCEREAPPAVVF
CTAHDEFALEAFQVSAVGYLVKPVRSEHLVEALRKAERPNRVQLAALTRPAAESGSGPRSHISARTRKGIELIPLDQVIY
FIADHKYVTLRHEGGEVLLDEPLKALEDEFGDRFVRIHRNALVARERIERLQRTPLGHFQLFLRGLNGDALIVSRRHVAG
VRKMMQQL
>Mature_248_residues
MNVLIVDDEPLARERLSRMVNEIEGYRVLEPSASNGEEALALIEAHKPDVVLLDIRMPGLDGLQVAARLCEREAPPAVVF
CTAHDEFALEAFQVSAVGYLVKPVRSEHLVEALRKAERPNRVQLAALTRPAAESGSGPRSHISARTRKGIELIPLDQVIY
FIADHKYVTLRHEGGEVLLDEPLKALEDEFGDRFVRIHRNALVARERIERLQRTPLGHFQLFLRGLNGDALIVSRRHVAG
VRKMMQQL

Specific function: Positive regulator of the algD gene, which codes for a GDP-mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=248, Percent_Identity=32.258064516129, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788724, Length=250, Percent_Identity=28, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788222, Length=173, Percent_Identity=30.635838150289, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=135, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=38.8349514563107, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27851; Mature: 27851

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIVDDEPLARERLSRMVNEIEGYRVLEPSASNGEEALALIEAHKPDVVLLDIRMPGL
CEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHEEEEECCCCCEEEEEEECCCC
DGLQVAARLCEREAPPAVVFCTAHDEFALEAFQVSAVGYLVKPVRSEHLVEALRKAERPN
CHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
RVQLAALTRPAAESGSGPRSHISARTRKGIELIPLDQVIYFIADHKYVTLRHEGGEVLLD
CEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHEECCEEEEEEECCCCEEHH
EPLKALEDEFGDRFVRIHRNALVARERIERLQRTPLGHFQLFLRGLNGDALIVSRRHVAG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEHHHHHH
VRKMMQQL
HHHHHHHC
>Mature Secondary Structure
MNVLIVDDEPLARERLSRMVNEIEGYRVLEPSASNGEEALALIEAHKPDVVLLDIRMPGL
CEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHEEEEECCCCCEEEEEEECCCC
DGLQVAARLCEREAPPAVVFCTAHDEFALEAFQVSAVGYLVKPVRSEHLVEALRKAERPN
CHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
RVQLAALTRPAAESGSGPRSHISARTRKGIELIPLDQVIYFIADHKYVTLRHEGGEVLLD
CEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHEECCEEEEEEECCCCEEHH
EPLKALEDEFGDRFVRIHRNALVARERIERLQRTPLGHFQLFLRGLNGDALIVSRRHVAG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEHHHHHH
VRKMMQQL
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493441; 10984043; 2544550; 8159168 [H]