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The map label for this gene is trpB [H]

Identifier: 66043305

GI number: 66043305

Start: 37998

End: 39227

Strand: Reverse

Name: trpB [H]

Synonym: Psyr_0034

Alternate gene names: 66043305

Gene position: 39227-37998 (Counterclockwise)

Preceding gene: 66043307

Following gene: 66043304

Centisome position: 0.64

GC content: 61.95

Gene sequence:

>1230_bases
ATGACCCAGACCAATTTCCGCAGCGGCCCCGACGCCAACGGCCTGTTCGGCTCATTCGGCGGCCGCTACGTGGCTGAAAC
CCTGATGCCGCTGGTGTTAGACCTCAACCGCGAGTACGAAGCGGCCAAGGCCGACCCGGAATTCATCAAAGAAATGGCTT
ACTTTCAGCGCGATTACGTGGGCCGTCCCAACCCGCTGTACTTCGCCGAACGCCTGACCGAATTCTGCGGCGGCGCGAAG
ATCTACTTCAAGCGCGAAGAGCTCAATCACACCGGCGCGCACAAGATCAACAACTGCATCGGCCAGGTACTGCTGGCCAA
GCGCATGGGCAAAAAACGCCTGATCGCGGAAACCGGCGCCGGCATGCACGGCGTTGCCACTGCTACCGTTGCTGCACGTT
TCGGTCTGCCTTGCGTGATCTACATGGGCGCTACCGACATCGAGCGTCAGCAGGCCAACGTGTTCCGCATGAGGCTGCTG
GGCGCTGAAATCGTTCCGGTCACCTCCGGCACCGGCACCCTGAAAGATGCGATGAACGAAGCGCTGCGTGACTGGGTGAC
CAACGTCGACGACACTTTCTACCTGATCGGCACCGTGGCAGGCCCGCACCCTTACCCGGCGATGGTCCGTGACTTCCAGG
CCATCATCGGCAAGGAAACCAAAGAGCAGATGCTGGAGAAGGAAGGTCGTCTGCCGGACAGCCTGGTTGCCTGTGTCGGT
GGTGGTTCCAACGCCATGGGCCTGTTTCATCCGTTCCTGGATGACGCCAGCGTGGAAATCATCGGCGTCGAGGCGGGCGG
TCATGGTGTCAGCACCGACAAGCACGCGGCCAGCCTGAACGGCGGCGTACCGGGCGTGCTGCACGGCAACCGCACTTACC
TGCTGCAGGACGGCGACGGGCAGATCACTGATGCACACTCGATCTCTGCCGGCCTGGACTACCCCGGCATCGGCCCGGAA
CACGCATTCCTGCACGAAGTGAAGCGCGTCGAATACGTCAGCATCACCGATGACGAAGCGCTGGACGCTTTCCATCAGTG
CTGCCTGCTCGAAGGCATCATCCCGGCGCTGGAAACCGCTCACGCCCTGGCCGAAGCCATGAAGCGCGCGACCAACCTGC
GCGATGATCACCTGATGGTCGTGTGCCTGTCCGGGCGCGGCGACAAAGACATGCAAACCGTCATGAACCACATGGCCGCC
GCCGAACACACTCAGGAGCAGCTGGTATGA

Upstream 100 bases:

>100_bases
AGCGATCTTATCGGTTTTCATCCGGCCTTGCGCTGGTTAAAGTGGACCCATTGCCAATACGGCTCAACCTATTCGCCCAA
TACTGCAACTGGAGCACTTC

Downstream 100 bases:

>100_bases
GCCGTCTAGAACATCGTTTCGCCCAGCTTAAAACCGAAGGTCGTGCGGCGCTGGTCACCTTCATCACCGCCGGTGACCCT
GGCTACGACACCTCGCTGAA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTQTNFRSGPDANGLFGSFGGRYVAETLMPLVLDLNREYEAAKADPEFIKEMAYFQRDYVGRPNPLYFAERLTEFCGGAK
IYFKREELNHTGAHKINNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMRLL
GAEIVPVTSGTGTLKDAMNEALRDWVTNVDDTFYLIGTVAGPHPYPAMVRDFQAIIGKETKEQMLEKEGRLPDSLVACVG
GGSNAMGLFHPFLDDASVEIIGVEAGGHGVSTDKHAASLNGGVPGVLHGNRTYLLQDGDGQITDAHSISAGLDYPGIGPE
HAFLHEVKRVEYVSITDDEALDAFHQCCLLEGIIPALETAHALAEAMKRATNLRDDHLMVVCLSGRGDKDMQTVMNHMAA
AEHTQEQLV

Sequences:

>Translated_409_residues
MTQTNFRSGPDANGLFGSFGGRYVAETLMPLVLDLNREYEAAKADPEFIKEMAYFQRDYVGRPNPLYFAERLTEFCGGAK
IYFKREELNHTGAHKINNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMRLL
GAEIVPVTSGTGTLKDAMNEALRDWVTNVDDTFYLIGTVAGPHPYPAMVRDFQAIIGKETKEQMLEKEGRLPDSLVACVG
GGSNAMGLFHPFLDDASVEIIGVEAGGHGVSTDKHAASLNGGVPGVLHGNRTYLLQDGDGQITDAHSISAGLDYPGIGPE
HAFLHEVKRVEYVSITDDEALDAFHQCCLLEGIIPALETAHALAEAMKRATNLRDDHLMVVCLSGRGDKDMQTVMNHMAA
AEHTQEQLV
>Mature_408_residues
TQTNFRSGPDANGLFGSFGGRYVAETLMPLVLDLNREYEAAKADPEFIKEMAYFQRDYVGRPNPLYFAERLTEFCGGAKI
YFKREELNHTGAHKINNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMRLLG
AEIVPVTSGTGTLKDAMNEALRDWVTNVDDTFYLIGTVAGPHPYPAMVRDFQAIIGKETKEQMLEKEGRLPDSLVACVGG
GSNAMGLFHPFLDDASVEIIGVEAGGHGVSTDKHAASLNGGVPGVLHGNRTYLLQDGDGQITDAHSISAGLDYPGIGPEH
AFLHEVKRVEYVSITDDEALDAFHQCCLLEGIIPALETAHALAEAMKRATNLRDDHLMVVCLSGRGDKDMQTVMNHMAAA
EHTQEQLV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=389, Percent_Identity=54.7557840616967, Blast_Score=437, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=380, Percent_Identity=56.3157894736842, Blast_Score=458, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44452; Mature: 44321

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTNFRSGPDANGLFGSFGGRYVAETLMPLVLDLNREYEAAKADPEFIKEMAYFQRDYV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC
GRPNPLYFAERLTEFCGGAKIYFKREELNHTGAHKINNCIGQVLLAKRMGKKRLIAETGA
CCCCCHHHHHHHHHHHCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCC
GMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMRLLGAEIVPVTSGTGTLKDAMNE
CCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHH
ALRDWVTNVDDTFYLIGTVAGPHPYPAMVRDFQAIIGKETKEQMLEKEGRLPDSLVACVG
HHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHEEEC
GGSNAMGLFHPFLDDASVEIIGVEAGGHGVSTDKHAASLNGGVPGVLHGNRTYLLQDGDG
CCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEECCEEEEEECCCC
QITDAHSISAGLDYPGIGPEHAFLHEVKRVEYVSITDDEALDAFHQCCLLEGIIPALETA
CEECCCCCCCCCCCCCCCCHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
HALAEAMKRATNLRDDHLMVVCLSGRGDKDMQTVMNHMAAAEHTQEQLV
HHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQTNFRSGPDANGLFGSFGGRYVAETLMPLVLDLNREYEAAKADPEFIKEMAYFQRDYV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC
GRPNPLYFAERLTEFCGGAKIYFKREELNHTGAHKINNCIGQVLLAKRMGKKRLIAETGA
CCCCCHHHHHHHHHHHCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCC
GMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMRLLGAEIVPVTSGTGTLKDAMNE
CCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHH
ALRDWVTNVDDTFYLIGTVAGPHPYPAMVRDFQAIIGKETKEQMLEKEGRLPDSLVACVG
HHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHEEEC
GGSNAMGLFHPFLDDASVEIIGVEAGGHGVSTDKHAASLNGGVPGVLHGNRTYLLQDGDG
CCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEECCEEEEEECCCC
QITDAHSISAGLDYPGIGPEHAFLHEVKRVEYVSITDDEALDAFHQCCLLEGIIPALETA
CEECCCCCCCCCCCCCCCCHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
HALAEAMKRATNLRDDHLMVVCLSGRGDKDMQTVMNHMAAAEHTQEQLV
HHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA